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Volumn 823, Issue 2, 2005, Pages 195-202
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Stereoselective analysis of metoprolol and its metabolites in rat plasma with application to oxidative metabolism
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Author keywords
CYP2D6; Enantiomers; Metabolism; Metoprolol; Pharmacokinetics; Rats
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Indexed keywords
BLOOD;
FLUORESCENCE;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
ISOMERS;
LIVING SYSTEMS STUDIES;
METABOLISM;
METABOLITES;
PHARMACOKINETICS;
CYP 2D6;
ENANTIOMERS;
METOPROLOL;
RATS;
DRUG PRODUCTS;
ALPHA HYDROXYMETOPROLOL;
DRUG METABOLITE;
METOPROLOL;
O NORMETOPROLOL;
UNCLASSIFIED DRUG;
AEROBIC METABOLISM;
ANIMAL EXPERIMENT;
AREA UNDER THE CURVE;
ARTICLE;
BLOOD SAMPLING;
CHIRAL CHROMATOGRAPHY;
CONFIDENCE INTERVAL;
CONTROLLED STUDY;
DRUG METABOLISM;
ENANTIOMER;
FLUORESCENCE;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
ISOMER;
KINETICS;
NONHUMAN;
PARAMETER;
PLASMA;
PRIORITY JOURNAL;
RAT;
STEREOCHEMISTRY;
TIME;
ADRENERGIC BETA-ANTAGONISTS;
ANIMALS;
AREA UNDER CURVE;
CALIBRATION;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
CIRCULAR DICHROISM;
HALF-LIFE;
MALE;
METOPROLOL;
RATS;
RATS, WISTAR;
REPRODUCIBILITY OF RESULTS;
STEREOISOMERISM;
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EID: 23644452118
PISSN: 15700232
EISSN: None
Source Type: Journal
DOI: 10.1016/j.jchromb.2005.06.038 Document Type: Article |
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Times cited : (34)
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References (20)
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