Extraesophageal manifestations of gastroesophageal reflux disease: Real or imagined?

Current Opinion in Gastroenterology

Volumn 26, Issue 4, 2010, Pages 389-394

  Moore, John M ^a   Vaezi, Michael F ^a  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Asthma; Chronic cough; Chronic laryngitis; Extraesophageal reflux syndrome; Reflux

Indexed keywords

ESOMEPRAZOLE; OMEPRAZOLE; PLACEBO; PROTON PUMP INHIBITOR; RANITIDINE;

ASTHMA; CLINICAL TRIAL; COUGHING; DISEASE ASSOCIATION; ESOPHAGEAL PH MONITORING; GASTROESOPHAGEAL REFLUX; HUMAN; LARYNGITIS; LARYNGOPHARYNGEAL REFLUX; OUTCOME ASSESSMENT; REVIEW; RISK FACTOR; STOMACH FUNDOPLICATION; COMPLICATION; COUGH;

ASTHMA; COUGH; ESOPHAGEAL PH MONITORING; GASTROESOPHAGEAL REFLUX; HUMANS; LARYNGITIS; PROTON PUMP INHIBITORS; RISK FACTORS;

EID: 77954143635     PISSN: 02671379     EISSN: None     Source Type: Journal    
DOI: 10.1097/MOG.0b013e32833adc8d     Document Type: Review

References (58)

1. Vakil N, van Zanten SV, Kahrilas P, et al. The Montreal definition and classification of gastroesophageal reflux disease. Am J Gastroenterol 2006; 101:1900-1920.
2. Field SK, Evans JA, Price LM. The effects of acid perfusion of the esophagus on ventilation and respiratory sensation. Am J Respir Crit Care Med 1998; 157:1058-1062.
3. Ing AJ, Ngu MC, Breslin AB. Pathogenesis of chronic persistent cough associated with gastro-esophageal reflux. Am J Respir Crit Care Med 1994; 149:160-167.
4. Adhami T, Goldblum JR, Richter JE, et al. The role of gastric and duodenal agents in the laryngeal injury: an experimental canine model. Am J Gastro-enterol 2004; 99:2098-2106.
5. Tuchman DN, Boyle JT, Pack Al, et al. Comparison of airway responses following tracheal or esophageal acidification in the cat. Gastroenterology 1984; 87:872-881.
6. Delahunty JE, Cherry J. Experimentally produced vocal cord granulomas. Laryngoscope 1968; 78:1941-1947.
7. Little FB, Koufman JA, Kohut RI, et al. Effect of gastric acid on the pathogen-esis of subglottic stenosis. Ann Otol Rhinol Laryngol 1985; 94:516-519.
8. Vaezi MF. Sensitivity and specificity of reflux-attributed laryngeal lesions: experimental and clinical evidence. Am J Med 2003; suppl 3A:97S-104S.
9. Kahrilas PJ, Shaheen NJ, Vaezi MF. American Gastroenterological Associa-tion Institute technical review of the management of gastroesophageal reflux disease. Gastroenterology 2008; 135:1383-1413.
10. Kenneth R, Devault DOC. Updated guidelines for the diagnosis and treatment of gastroesophageal reflux disease. Am J Gastroenterol 2005; 100:190-200.
11. Koufman JA. The otolaryngologic manifestations of gastroesophageal reflux disease (GERD): a clinical investigation of 225 patients using ambulatory 24-h pH monitoring and an experimental investigation of the role of acid pepsin in the development of laryngeal injury. Laryngoscope 1991; 101 (Suppl 53):1-78.
12. Park W, Hicks DM, Khandwala F, et al. Laryngopharyngeal reflux: prospective cohort study evaluating optimal dose of proton-pump inhibitor therapy and pretherapy predictors of response. Laryngoscope 2005; 115:1230-1238.
13. Hanson DG, Kamel PL, Kahrilas PJ. Outcomes of antireflux therapy for the treatment of chronic laryngitis. Ann Otol Rhinol Laryngol 1995; 104:550-555.
14. Kamel PL, Hanson DG, Kahrilas PJ. Omeprazole for the treatment of posterior laryngitis. Am J Med 1994; 96:321-326.
15. Vaezi MF, Hicks DM, Abelson TI, et al. Laryngeal signs and symptoms and gastroesophageal reflux disease: a critical assessment of cause and effect association. Clin Gastroenterol Hepatol 2003; 1:333-344.
16. Qadeer MA, Phillips CO, Lopez AR, et al. Proton pump inhibitor therapy for suspected GERD-related laryngitis: a meta-analysis of randomized controlled trials. Am J Gastroenterol 2006; 101:2646-2654.
17. Baldi F, Cappiello R, Cavoli C, et al. Proton pump inhibitor treatment of patients with gastroesophageal reflux-related chronic cough: a comparison between two different daily doses of lansoprazole. World J Gastroenterol 2006; 12:82-88.
18. Vaezi MF, Schroeder PL, Richter JE. Reproducibility of proximal probe pH parameters in 24-h ambulatory esophageal pH monitoring. Am J Gastroenterol 1997; 92:825-829.
19. Jacob P, Kahrilas PJ, Herzon G. Proximal esophageal pH-metry in patients with 'reflux laryngitis'. Gastroenterology 1991; 100:305-310.
20. Cool M, Poelmans J, Feenstra L, et al. Characteristics and clinical relevance of proximal esophageal pH monitoring. Am J Gastroenterol 1997; 92:825-829.
21. Ikuo J, Richter JE. ACG practice guidelines: esophageal reflux testing. Am J Gastroenterol 2007; 102:668-685.
22. Sun G, Muddana S, Slaughter JC, et al. A new pH catheter for laryn-gopharyngeal reflux: normal values. Laryngoscope 2009; 119:1639 - 1643.
23. Pritchett JM, Aslam M, Slaughter JC, et al. Efficacy of esophageal impedance/ pH monitoring in patients with refractory gastroesophageal reflux disease, on and off therapy. Clin Gastroenterol Hepatol 2009; 7:743-748.
24. Ing AJ, Ngu MC, Breslin AB. Pathogenesis of chronic persistent cough associated with gastroesophageal reflux. Am J Respir Crit Care 1994; 149:160-167.
25. Smith J, Woodcock A. New developments in the objective assessment of cough. Lung 2008; 186 (Suppl 1):S48-S54.
26. Everett CF, Morice AH. Clinical history in gastroesophageal cough. Respir Med 2007; 101:345-348.
27. McGarvey LP, Heaney LG, Lawson JT, et al. Evaluation and outcome of patients with chronic nonproductive cough using a comprehensive diagnostic protocol. Thorax 1998; 53:738-743.
28. Irwin RS, Curley FJ, French CL. Chronic cough: the spectrum and frequency of causes, key components of the diagnostic evaluation and outcome of specific therapy. Am Rev Respir Dis 1990; 141:640-647.
29. Irwin RS, French CL, Curley FJ, et al. Chronic cough due to gastroesophageal reflux: clinical, diagnostic, and pathogenetic aspects. Chest 1993; 104: 1511-1517.
30. Chandra KMD, Harding SM. Therapy insight: treatment of gastroesophageal reflux in adults with chronic cough. Nat Clin Pract Gastroenterol Hepatol 2007; 4:604-613.
31. Irwin RS. Chronic cough to gastroesophageal reflux disease: ACCP evidence-based clinically practice guidelines. Chest 2006; 129 (1 Suppl):80S-94S.
32. Tokayer AZ. Gastroesophageal reflux disease and chronic cough. Lung 2008; 186 (Supp l):S29-S34.
33. Patterson WG, Murat BW. Combined ambulatory esophageal manometry and dual-probe pH-metry in evaluation of patients with chronic unexplained cough. Dig Dis Sci 1994; 39:1117-1125.
34. Irwin RS, Zawacki JK, Wilson MM, et al. Chronic cough due to gastroesophageal reflux disease: failure to resolve despite total/near-total elimination of esophageal acid. Chest 2002; 121:1132-1140.
35. Blondeau K, Dupont LJ, Mertens V, et al. Improved diagnosis of gastro-oesophageal reflux in patients with unexplained chronic cough. Ailment Pharmacol Ther 2007; 25:723-732.
36. Shay S, Tutuian R, Sifrim D, et al. Twenty-four hour ambulatory simultaneous impedance and pH monitoring: a multicenter report of normal values from 60 healthy volunteers. Am J Gastroenterol 2004; 99:1037-1043.
37. Zerbib F, des Varannes SB, Roman S, et al. Normal values and day-to-day variability of 24-h ambulatory oesophageal impedance-pH monitoring in a Belgian-French cohort of healthy subjects. Ailment Pharmacol Ther 2005; 22:1011-1021.
38. Tutian R, Mainie I, Agarawal A, et al. Nonacid reflux in patients with chronic cough on acid-suppressive therapy. Chest 2006; 130:386-391.
39. Patterson N, Mainie I, Rafferty G, et al. Nonacid reflux episodes reaching the pharynx are important factors associated with cough. J Clin Gastroenterol 2009; 43:414-419.
40. Sifrim D, Dupont L, Blondeau K, et al. Weakly acidic reflux in patients with chronic unexplained cough during 24 h pressure, pH, and impedance monitoring. Gut 2005; 54:449-454.
41. Decalmer S, Kelsall A, Jones H, et al. Temporal relationships between reflux and cough. Am J Respir Crit Care Med 2009; 179:A5765.
42. Vaezi MF, Richter JE. Twenty-four hour ambulatory esophageal pH monitoring in the diagnosis of acid reflux-related chronic cough. South Med J 1997; 90:305-311.
43. Waring JP, Lacyo L, Hunter J, et al. Chronic cough and hoarseness in patients with severe gastroesophageal reflux disease. Diagnosis and response to therapy. Dig Dis Sci 1995; 40:1093-1097.
44. Chang AB, Lasserman TJ, Kiljander TO, et al. Systematic review and metaanalysis of randomised controlled trials of gastro-oesophageal reflux interventions for chronic cough associated with gastro-oesophageal reflux. BMJ 2006; 332:11-17.
45. Parsons JP, Mastronade JG. Gastroesophageal reflux disease and asthma. Curr Opin Pulm Med 2010; 16:60-63.
46. Mastronade JG, Anthonisen NR, Castro M, et al. Efficacy of esomeprazole for treatment of poorly controlled asthma. N Engl J Med 2009; 360:1487-1499.
47. Gastal OL, Castell JA, Castell DO. Frequency and site of gastroesophageal reflux in patients with chest symptoms. Studies using proximal and distal pH monitoring. Chest 1994; 106:1793-1796.
48. Kiljander TO, Salomaa EM, Hietanen EK, et al. Gastroesophageal reflux in asthmatics: a double blind, placebo-controlled crossover study with omeprazole. Chest 1999; 116:1257-1264.
49. Sontag SJ, O'Connell S, Kandelwal S, et al. Asthmatic with gastroesophageal reflux: long term results of a randomized trial of medical and surgical antireflux therapies. Am J Gastroenterol 2003; 98:987-999.
50. Kiljander TO, Harding SM, Field SK, et al. Effects of esomeprazole 40 mg twice daily on asthma: a randomized placebo-controlled trial. Am J Respir Crit Care Med 2006; 173:1091-1097.
51. Littner MR, Leung FW, Ballard ED, et al. Effects of 24 weeks of lansoprazole therapy on asthma symptoms, exacerbations, quality of life, and pulmonary function in adult asthmatic patients with acid reflux symptoms. Chest 2005; 128:1128-1135.
52. The American Lung Association Asthma Clinical Research Centers. Efficacy of esomeprazole for treatment of poorly controlled asthma. N Engl J Med 2009; 360:1487-1499.
53. National Asthma Education and Prevention Program. Expert Panel Report 3 (EPR3): guidelines for the diagnosis and management of asthma: full report. Bethesda, MD: National Heart, Lung, and Blood Institute; 2007. http://www.nhlbi.nih.gov/guidelines/asthma/asthgldln.htm. [Accessed 27 December 2009].
54. Hicks DM, Ours TM, Alelson TI, et al. The prevalence of hypopharynx findings associated with gastroesophageal reflux in normal volunteers. J Voice 2002; 16:564-579.
55. Joniau S, Bradshaw A, Esterman A, et al. Reflux laryngitis: a systematic review. Otolaryngol Head Neck Surg 2007; 136:686-692.
56. Kotby MN, Hassan O, El-Makhzangy AM, et al. Gastroesophageal reflux/ laryngopharyngeal reflux disease: a critical analysis of the literature. Eur Arch Otorhinolaryngol 2010; 267:171-179.
57. Qadeer Ma, Swoger J, Milstein C, et al. Correlation between symptoms and laryngeal signs in laryngopharyngeal reflux. Laryngoscope 2005; 115:1947-1952.
58. Vaezi MF, Richter JE, Stasney CR, et al. Treatment of chronic posterior laryngitis with esomeprazole. Laryngoscope 2006; 116:254-260.