A single nucleotide polymorphism in the E-cadherin gene promoter -160 C/A is associated with risk of nasopharyngeal cancer

Clinica Chimica Acta

Volumn 411, Issue 17-18, 2010, Pages 1253-1257

  Ben Nasr, Hela ^a   Hamrita, Bechr ^a   Batbout, Mariem ^a   Gabbouj, Sallouha ^a   Bouaouina, Noureddine ^a,b   Chouchane, Lotfi ^a,c   Chahed, Karim ^a,d  

^a UNIVERSITY OF MONASTIR   (Tunisia)

^b FARHAT HACHED HOSPITAL   (Tunisia)

^c WEILL CORNELL MEDICAL COLLEGE   (Qatar)

^d UNIVERSITY OF SFAX   (Tunisia)

Author keywords

E cadherin; Nasopharyngeal carcinoma; Polymorphism; Prognosis; Susceptibility

Indexed keywords

UVOMORULIN; CADHERIN; PRIMER DNA;

ADULT; ALLELE; ARTICLE; CANCER RISK; CANCER STAGING; CANCER SURVIVAL; CONTROLLED STUDY; DISEASE FREE SURVIVAL; FEMALE; GENETIC ASSOCIATION; GENETIC MARKER; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; MALE; NASOPHARYNX CANCER; ONSET AGE; OVERALL SURVIVAL; POLYMERASE CHAIN REACTION; POPULATION RESEARCH; PRIORITY JOURNAL; PROGNOSIS; PROMOTER REGION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SINGLE NUCLEOTIDE POLYMORPHISM; TRANSCRIPTION INITIATION SITE; TUMOR VOLUME; TUNISIA; GENETIC PREDISPOSITION; GENETICS; NASOPHARYNX TUMOR; NUCLEOTIDE SEQUENCE; RISK FACTOR;

BASE SEQUENCE; CADHERINS; DNA PRIMERS; GENETIC PREDISPOSITION TO DISEASE; HUMANS; NASOPHARYNGEAL NEOPLASMS; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; RISK FACTORS;

EID: 77954142392     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cca.2010.05.001     Document Type: Article

References (24)

1. Wei W.I., Shum J.S.T. Nasopharyngeal carcinoma. Lancet 2005, 365:2041-2054.
2. Zheng Z., Pan J., Chu B., Wong Y.C., Cheung A.L., Tsao S.W. Downregulation and abnormal expression of E-cadherin and beta-catenin in nasopharyngeal carcinoma: close association with advanced disease stage and lymph node metastasis. Hum Pathol 1999, 30:458-466.
3. Takeichi M. Cadherin cell adhesion receptors as a morphogenetic regulator. Science 1991, 22:1451-1455.
4. Vleminckx K., Vakaet L., Mareel M., Fiers W., van Roy F. Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role. Cell 1991, 66:107-119.
5. Pignatelli M., Ansari T.W., Gunter P., et al. Loss of membranous E-cadherin expression in pancreatic cancer: correlation with lymph node metastasis, high grade, and advanced stage. J Pathol 1994, 174:243-248.
6. Schipper J.H., Frixen U.H., Behrens J., Unger A., Jahnke K., Birchmeier W. E-cadherin expression in squamous cell carcinomas of head and neck: inverse correlation with tumor dedifferentiation and lymph node metastasis. Cancer Res 1991, 51:6328-6337.
7. Li L.C., Chui R.M., Sasaki M., et al. A single nucleotide polymorphism in the E-cadherin gene promoter alters transcriptional activities. Cancer Res 2000, 60:873-876.
8. Verhage B.A., van Houwelingen K., Ruijter T.E., Kiemeney L.A., Schalken J.A. Single-nucleotide polymorphism in the E-cadherin gene promoter modifies the risk of prostate cancer. Int J Cancer 2002, 100:683-685.
9. Olerup O., Zetterquist H. HLA-DR typing by PCR amplification with sequence specific primers (PCR-SSP) in 2 hours: an alternative to serological DR typing in clinical practice including donor-recipient matching in cadaveric transplantation. Tissue Antigens 1992, 39:225-235.
10. Kamoto T., Isogawa Y., Shimizu Y., et al. Association of a genetic polymorphism of the E-cadherin gene with prostate cancer in a Japanese population. Jpn J Clin Oncol 2005, 35:158-161.
11. Conacci-Sorrell M., Zhurinsky J., Ben-Ze'ev A. The cadherin-catenin adhesion system in signaling and cancer. J Clin Invest 2002, 109:987-991.
12. Ribeiro-Filho L.A., Franks J., Sasaki M., et al. CpG hypermethylation of promoter region and inactivation of E-cadherin gene in human bladder cancer. Mol Carcinog 2002, 34:187-198.
13. Scarpulla R.C. Nuclear activators and coactivators in mammalian mitochondrial biogenesis. Biochim Biophys Acta 2002, 1576:1-14.
14. Morrish F., Giedt C., Hockenbery D. c-MYC apoptotic function is mediated by NRF-1 target genes. Genes Dev 2003, 17:240-255.
15. Tsukino H., Kuroda Y., Imai H., et al. Lack of evidence for the association of E-cadherin gene polymorphism with increased risk or progression of prostate cancer. Urol Int 2004, 72:203-207.
16. Porter T.R., Richards F.M., Houlston R.S., et al. Contribution of cyclin d1 (CCND1) and E-cadherin (CDH1) polymorphisms to familial and sporadic colorectal cancer. Oncogene 2002, 21:1928-1933.
17. Tsukino H., Kuroda Y., Nakao H., et al. E-cadherin gene polymorphism and risk of urothelial cancer. Cancer Lett 2003, 195:53-58.
18. Wang G.Y., Lu C.Q., Zhang R.M., Hu X.H., Luo Z.W. The E-cadherin gene polymorphism -160 C-A and cancer risk: A HuGE review and meta-analysis of 26 case-control studies. Am J Epidemiol 2008, 167:7-14.
19. Stiller C.A. International variations in the incidence of childhood carcinomas. Cancer Epidemiol Biomark Prev 1994, 3:305-310.
20. Ben Nasr H., Chahed K., Remadi S., Zakhama A., Chouchane L. Expression and clinical sig.nificance of latent membrane protein-1, matrix metalloproteinase-1 and Ets-1 transcription factor in tunisian nasopharyngeal carcinoma patients. Arch Med Res 2009, 40:196-203.
21. Tsai C.N., Tsai C.L., Tse K.P., Chang H.Y., Chang Y.S. The Epstein-Barr virus oncogene product, latent membrane protein 1, induces the downregulation of E-cadherin gene expression via activation of DNA methyltransferases. Proc Natl Acad Sci USA 2002, 99:10084-10089.
22. Sarrió D., Moreno-Bueno G., Hardisson D., et al. Epigenetic and genetic alterations of APC and CDH1 genes in lobular breast cancer: relationships with abnormal E-cadherin and catenin expression and microsatellite instability. Int J Cancer 2003, 106:208-215.
23. Li Z., Ren Y., Lin S.X., Liang Y.J., Liang H.Z. Association of E-cadherin and beta-catenin with metastasis in nasopharyngeal carcinoma. Chin Med J 2004, 117:1232-1239.
24. Niemhom S., Kitazawa S., Kitazawa R., Maeda S., Leopairat J. Hypermethylation of epithelial-cadherin gene promoter is associated with Epstein-Barr virus in nasopharyngeal carcinoma. Cancer Detect Prev 2008, 32:127-134.