Rolipram and sp600125 suppress the early increase in ptp1b expression during cerulein-induced pancreatitis in rats

Pancreas

Volumn 39, Issue 5, 2010, Pages 639-645

  Sarmiento, Nancy ^a   Sánchez Bernal, Carmen ^a   Pérez, Nieves ^a   Sardina, José L ^a   Mangas, Arturo ^a   Calvo, José J ^a   Sánchez Yagüe, Jesús ^a  

^a UNIVERSITY OF SALAMANCA   (Spain)

Author keywords

acute pancreatitis; cerulein; PTP1B; rolipram; SP600125

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CERULETIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; PHOSPHODIESTERASE IV; PROTEIN TYROSINE PHOSPHATASE 1B; ROLIPRAM; STRESS ACTIVATED PROTEIN KINASE; VINBLASTINE SULFATE; ANTHRA(1,9-CD)PYRAZOL-6(2H)-ONE; ANTHRACENE DERIVATIVE; CYCLIC AMP; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHODIESTERASE INHIBITOR; PROTEIN KINASE INHIBITOR; PTPN1 PROTEIN, RAT; VINBLASTINE;

ACUTE PANCREATITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; DRUG EFFECT; ENZYME INHIBITION; MALE; NEUTROPENIA; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; RAT; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; CHEMICALLY INDUCED; DISEASE MODEL; ENZYMOLOGY; METABOLISM; PANCREATITIS; WISTAR RAT;

ANIMALS; ANTHRACENES; CAERULEIN; CYCLIC AMP; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 4; DISEASE MODELS, ANIMAL; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NEUTROPENIA; PANCREATITIS; PHOSPHODIESTERASE INHIBITORS; PROTEIN KINASE INHIBITORS; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1; RATS; RATS, WISTAR; ROLIPRAM; VINBLASTINE; CERULETIDE;

EID: 77954137522     PISSN: 08853177     EISSN: None     Source Type: Journal    
DOI: 10.1097/MPA.0b013e3181c314b3     Document Type: Article

References (30)

1. Alonso R, Montero A, Arévalo M, et al. Platelet-activating factor mediates pancreatic function derangement in caerulein-induced pancreatitis in rats. Clin Sci. 1994;87:85-90.
2. Pescador R, Manso MA, Revollo AJ, et al. Effect of chronic administration of hydrocortisone on the induction and evolution of acute pancreatitis induced by cerulean. Pancreas. 1995;11:165-172.
3. Yönetçi N, Orucł N, Ozütemiz AO, et al. Effects of mast-cell stabilization in caerulein-induced acute pancreatitis in rats. Int J Pancreatol. 2001; 29:163-171.
4. Zhao M, Xue DB, Zheng B, et al. Induction of apoptosis by artemisin relieving the severity of inflammation in caerulein-induced acute pancreatitis. World J Gastroenterol. 2007;14:5612-5617.
5. Ji B, Chen X, Misek DE, et al. Pancreatic gene expression during the initiation of acute pancreatitis: identification of EGR-1 as a key regulator. Physiol Genomics. 2003;14:59-72.
6. Rivard N, Rydzewska G, Lods J-S, et al. Pancreas growth, tyrosine kinase, PtdIns 3-kinase, and PLD involve high-affinity CCK-receptor occupation. Am J Physiol. 1994;266:G62-G70.
7. Rivard N, Rydzewska G, Lods JS, et al. Novel model of integration of signalling pathways in rat pancreatic acinar cells. Am J Physiol. 1995;269:G352-G362.
8. Widmann C, Gibson S, Jarpe MB, et al. Mitogen activated protein kinases: conservation of a three kinase module from yeast to human. Physiol Rev. 1999;79:143-180.
9. Minutoli L, Altavilla D, Marini H, et al. Protective effects of SP600125 a new inhibitor of c-Jun N-terminal kinase (JNK) and extracellular-regulated kinase (ERK1/2) in an experimental model of cerulein-induced pancreatitis. Life Sci. 2004;75:2853-2866.
10. Satoh A, Shimosegawa T, Satoh K, et al. Activation of A1-receptor pathway induces edema formation in the pancreas of rats. Gastroenterology. 2000;119:829-836.
11. Sato T, Otaka M, Odashima M, et al. Specific type IV phosphodiesterase inhibitor ameliorates cerulein-induced pancreatitis in rats. Biochem Biophys Res Commun. 2006;346:339-344.
12. Feick P, Gilhaus S, Blum IR, et al. Inhibition of amylase secretion from differentiated AR4-2J pancreatic acinar cells by an actin cytoskeleton controlled protein tyrosine phosphatase activity. FEBS Lett. 1999;451:269-274.
13. Hernández-Hernández A, Garabatos MN, Rodríguez MC, et al. Structural characteristics of a lipid peroxidation product, trans-2-nonenal, that favour inhibition of membrane associated phosphotyrosine phosphatase activity. Biochim Biophys Acta. 2005;1726:317-325.
14. Sánchez-Bernal C, García-Morales OH, Domínguez C, et al. Nitric oxide protects against pancreatic subcellular damage in acute pancreatitis. Pancreas. 2004;28:e9-e15.
15. Bourdeau A, Dubé N, Tremblay ML. Cytoplasmic protein tyrosine phosphatases, regulation and function: the roles of PTP1B and TC-PTP. Curr Opin Cell Biol. 2005;17:203-209.
16. Yu J-H, Kim K-H, Kim H. SOCS 3 and PPAR-F ligands inhibit the expression of IL-6 and TGF-A1 by regulating JAK2/STAT3 signalling in pancreas. Int J Biochem Cell Biol. 2008;40:677-688.
17. Case RM. Synthesis, intracellular transport and discharge of exportable proteins in the pancreatic acinar cell and other cells. Biol Rev Camb Philos Soc. 1978;53:211-354.
18. Kubish CH, Sans MD, Arumugan T, et al. Early activation of endoplasmic reticulum stress is associated with arginine-induced acute pancreatitis. Am J Physiol Gastrointest Liver Physiol. 2006;291: G238-G245.
19. Suyama K, Ohmuraya M, Hirota M, et al. C/EBP homologous protein is crucial for the acceleration of experimental pancreatitis. Biochem Biophys Res Commun. 2008;267:176-182.
20. Sarmiento N, Sánchez-Bernal C, Ayra M, et al. Changes in the expression and dynamics of SHP-1 and SHP-2 during cerulein-induced acute pancreatitis in rats. Biochim Biophys Acta. 2008;1782:271-279.
21. Wimmer M, Tag C, Schreimer D, et al. Protein tyrosine phosphatase 1B is located with glucagon vesicles, and its concentration is inversely correlated with the rate of glucagon secretion of INR1G9 cells. J Endocrinol. 2004;181:437-447.
22. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976;72:248-254.
23. Clemons AP, Holstein DM, Galli A, et al. Cerulein-induced acute pancreatitis in the rat is significantly ameliorated by treatment with MEK1/2 inhibitors U0126 and PD98059. Pancreas. 2002;25:251-259.
24. Hernández-Hernández A, Llanillo M, Rodríguez MC, et al. Amphiphilic and hydrophilic nature of sheep and human platelet phosphotyrosine phosphatase forms. Biochim Biophys Acta. 1999; 1419:195-206.
25. Hernández-Hernández A, Rodríguez MC, López-Revuelta A, et al. Alterations in erythrocyte membrane protein composition in advanced non-small cell lung cancer. Blood Cell Mol Dis. 2006;36:355-363.
26. Mayerle J, Schnekenburger J, Kruger B, et al. Extracellular cleavage of E-cadherin by leukocyte elastase during acute experimental pancreatitis in rats. Gastroenterology. 2005;129:1251-1267.
27. Semmler J, Wachtel H, Endres S. The specific type IV phosphodiesterase inhibitor rolipram suppresses tumor necrosis factor-α production by human mononuclear cells. Int J Immunopharmacol. 1993;15:409-413.
28. Gukovskaya AS, Gukovsky I, Zaninovic V, et al. Pancreatic acinar cells produce, release, and respond to tumor necrosis factor-alpha. Role in regulating cell death and pancreatitis. J Clin Invest. 1997;100: 1853-1862.
29. Hofken T, Keller N, Fleischer F, et al. Map kinase phosphatases (MKPs) are early responsive genes during induction of cerulein hyperstimulation pancreatitis. Biochem Biophys Res Commun. 2000; 276:680-685.
30. Boucher MJ, Duchesne C, Lainé J, et al. cAMP protection of pancreatic cancer cells against apoptosis induced by ERK inhibition. Biochem Biophys Res Commun. 2001;285:207-216.