메뉴 건너뛰기




Volumn 55, Issue 1, 2003, Pages 6-13

Pharmacokinetics of oral betaine in healthy subjects and patients with homocystinuria

Author keywords

Betaine; Homocysteine; Homocystinuria; Pharmacokinetics

Indexed keywords

BETAINE; DIMETHYLGLYCINE; DRUG METABOLITE;

EID: 0037241172     PISSN: 03065251     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2125.2003.01717.x     Document Type: Article
Times cited : (98)

References (22)
  • 1
    • 0025270591 scopus 로고
    • Molecular cloning of a plant betaine-aldehyde dehydrogenase, an enzyme implicated in adaptation to salinity and drought
    • Weretilnyk EA, Hanson AD. Molecular cloning of a plant betaine-aldehyde dehydrogenase, an enzyme implicated in adaptation to salinity and drought. Proc Natl Acad Sci USA 1990; 87: 2745-2749.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 2745-2749
    • Weretilnyk, E.A.1    Hanson, A.D.2
  • 4
    • 0033387845 scopus 로고    scopus 로고
    • Evidence for mitochondrial localization of betaine aldehyde dehydrogenase in rat liver: Purification, characterization, and comparison with human cytoplasmic E3 isozyme
    • Chern MK, Pietruszko R. Evidence for mitochondrial localization of betaine aldehyde dehydrogenase in rat liver: Purification, characterization, and comparison with human cytoplasmic E3 isozyme. Biochem Cell Biol 1999; 77: 179-187.
    • (1999) Biochem Cell Biol , vol.77 , pp. 179-187
    • Chern, M.K.1    Pietruszko, R.2
  • 5
    • 0028894492 scopus 로고
    • Molecular basis of osmotic regulation
    • Burg M. Molecular basis of osmotic regulation. Am J Physiol 1995; 268: F983-F996.
    • (1995) Am J Physiol , vol.268
    • Burg, M.1
  • 7
    • 0029995347 scopus 로고    scopus 로고
    • Treatment of hyperhomocystinemia: Physiological basis
    • Kang SS. Treatment of hyperhomocystinemia: Physiological basis. J Nutr 1996; 126: 1273S-5S.
    • (1996) J Nutr , vol.126
    • Kang, S.S.1
  • 8
    • 0035552975 scopus 로고    scopus 로고
    • Polymorphisms in the methylenetetrahydrofolate reductase gene. Clinical consequences
    • Schwahn B, Rozen R. Polymorphisms in the methylenetetrahydrofolate reductase gene. Clinical consequences. Am J Pharmacogenomics 2001; 1: 189-201.
    • (2001) Am J Pharmacogenomics , vol.1 , pp. 189-201
    • Schwahn, B.1    Rozen, R.2
  • 9
    • 0001439796 scopus 로고
    • Results of betaine treatment of atherosclerosis
    • Morrison LM. Results of betaine treatment of atherosclerosis. Am J Dig Dis 1952; 19: 381-384.
    • (1952) Am J Dig Dis , vol.19 , pp. 381-384
    • Morrison, L.M.1
  • 10
    • 0021267379 scopus 로고
    • Betaine in the treatment of homocystinuria due to 5,10-methylenetetrahydrofolate reductase deficiency
    • Wendel U, Bremer HJ. Betaine in the treatment of homocystinuria due to 5,10-methylenetetrahydrofolate reductase deficiency. Eur J Pediatr 1984; 142: 147-150.
    • (1984) Eur J Pediatr , vol.142 , pp. 147-150
    • Wendel, U.1    Bremer, H.J.2
  • 12
    • 0006302863 scopus 로고
    • The dietary treatment of homocystinuria
    • eds Carson NAJ, Raine DN. Edinburgh, London: Churchill Livingstone
    • Komrower GM, Sardharwalla IB. The dietary treatment of homocystinuria. In Inherited Disorders Of Sulfur Metabolism, eds Carson NAJ, Raine DN. Edinburgh, London: Churchill Livingstone, 1971; 234-263.
    • (1971) Inherited Disorders Of Sulfur Metabolism , pp. 234-263
    • Komrower, G.M.1    Sardharwalla, I.B.2
  • 13
    • 0019406681 scopus 로고
    • The use of betaine for the treatment of homocystinuria
    • Smolin LA, Benevenga NJ, Berlow S. The use of betaine for the treatment of homocystinuria. J Pediatr 1981; 99: 467-472.
    • (1981) J Pediatr , vol.99 , pp. 467-472
    • Smolin, L.A.1    Benevenga, N.J.2    Berlow, S.3
  • 14
    • 0031985357 scopus 로고    scopus 로고
    • Betaine dose and treatment intervals in therapy for homocystinuria due to 5,10-methylenetetrahydrofolate reductase deficiency
    • Sakura N, Ono H, Nomura S, Ueda H, Fujita N. Betaine dose and treatment intervals in therapy for homocystinuria due to 5,10-methylenetetrahydrofolate reductase deficiency. J Inher Metab Dis 1998; 21: 84-85.
    • (1998) J Inher Metab Dis , vol.21 , pp. 84-85
    • Sakura, N.1    Ono, H.2    Nomura, S.3    Ueda, H.4    Fujita, N.5
  • 16
    • 0031721546 scopus 로고    scopus 로고
    • Simple method for the routine determination of betaine and N.N-dimethylglycine in blood and urine
    • Laryea MD, Steinhagen F, Pawliczek S, Wendel U. Simple method for the routine determination of betaine and N.N-dimethylglycine in blood and urine. Clin Chem 1998; 44: 1937-1941.
    • (1998) Clin Chem , vol.44 , pp. 1937-1941
    • Laryea, M.D.1    Steinhagen, F.2    Pawliczek, S.3    Wendel, U.4
  • 17
    • 0027515431 scopus 로고
    • Serum betaine, N,N-dimethylglycine and N-methylglycine levels in patients with cobalamin and folate deficiency and related inborn errors of metabolism
    • Allen RH, Stabler SP, Lindenbaum J. Serum betaine, N,N-dimethylglycine and N-methylglycine levels in patients with cobalamin and folate deficiency and related inborn errors of metabolism. Metabolism 1993; 42: 1448-1460.
    • (1993) Metabolism , vol.42 , pp. 1448-1460
    • Allen, R.H.1    Stabler, S.P.2    Lindenbaum, J.3
  • 19
    • 0032772214 scopus 로고    scopus 로고
    • Identification of the second tonicity-responsive enhancer for the betaine transporter (BGT1) gene
    • Miyakawa H, Rim JS, Handler JS, Kwon HM. Identification of the second tonicity-responsive enhancer for the betaine transporter (BGT1) gene. Biochim Biophys Acta 1999; 1446: 359-364.
    • (1999) Biochim Biophys Acta , vol.1446 , pp. 359-364
    • Miyakawa, H.1    Rim, J.S.2    Handler, J.S.3    Kwon, H.M.4
  • 20
    • 0033583210 scopus 로고    scopus 로고
    • Interaction between dietary methionine and methyl donor intake on rat liver betaine-homocysteine methyltransferase gene expression and organization of the human gene
    • Park EI, Garrow TA. Interaction between dietary methionine and methyl donor intake on rat liver betaine-homocysteine methyltransferase gene expression and organization of the human gene. J Biol Chem 1999; 274: 7816-7824.
    • (1999) J Biol Chem , vol.274 , pp. 7816-7824
    • Park, E.I.1    Garrow, T.A.2
  • 21
    • 0032147170 scopus 로고    scopus 로고
    • Human betaine-homocysteine methyltransferase is a zinc metalloenzyme
    • Millian NS, Garrow TA. Human betaine-homocysteine methyltransferase is a zinc metalloenzyme. Arch Biochem Biophys 1998; 356: 93-98.
    • (1998) Arch Biochem Biophys , vol.356 , pp. 93-98
    • Millian, N.S.1    Garrow, T.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.