Light-induced isomerization of apoptolidin a leads to inversion of C2-C3 double bond geometry

Organic Letters

Volumn 12, Issue 13, 2010, Pages 2944-2947

  Bachmann, Brian O ^a   McNees, Ruth ^a   Melancon, Bruce J ^a   Ghidu, Victor P ^a   Clark, Rachel ^a   Crews, Brenda C ^a   Deguire, Sean M ^a   Marnett, Lawrence J ^a   Sulikowski, Gary A ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOLIDIN A; APOPTOLIDIN G; MACROLIDE; PYRONE DERIVATIVE;

ARTICLE; CELL SURVIVAL; CHEMISTRY; CONFORMATION; DOSE RESPONSE; DRUG EFFECT; DRUG SCREENING; HUMAN; ISOLATION AND PURIFICATION; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE; ULTRAVIOLET RADIATION;

CELL LINE, TUMOR; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MACROLIDES; MOLECULAR CONFORMATION; PYRONES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; ULTRAVIOLET RAYS;

EID: 77954118920     PISSN: 15237060     EISSN: 15237052     Source Type: Journal    
DOI: 10.1021/ol1009398     Document Type: Article

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