Transcallosal white matter degradation detected with quantitative fiber tracking in alcoholic men and women: Selective relations to dissociable Functions

Alcoholism: Clinical and Experimental Research

Volumn 34, Issue 7, 2010, Pages 1201-1211

  Pfefferbaum, Adolf ^a,b   Rosenbloom, Margaret J ^a,b   Fama, Rosemary ^a,b   Sassoon, Stephanie A ^a   Sullivan, Edith V ^b  

^a SRI INTERNATIONAL   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alcoholism; Ataxia; Corpus Callosum; Digit Symbol Test; Fiber Tracking; Sex

Indexed keywords

ADULT; ALCOHOL CONSUMPTION; ALCOHOLISM; ARTICLE; BRAIN FUNCTION; CONTROLLED STUDY; CORPUS CALLOSUM; DIFFUSION TENSOR IMAGING; FEMALE; FRACTIONAL ANISOTROPY; HUMAN; IMAGE PROCESSING; MAJOR CLINICAL STUDY; MALE; NEUROLOGIC DISEASE; NEUROPSYCHOLOGY; PRIORITY JOURNAL; PSYCHOMOTOR PERFORMANCE; SEX DIFFERENCE; STATE DEPENDENT LEARNING; WHITE MATTER DEGRADATION;

ADULT; ALCOHOLISM; ANISOTROPY; CORPUS CALLOSUM; DIFFUSION TENSOR IMAGING; FEMALE; HUMANS; MALE; MIDDLE AGED; NERVE FIBERS, MYELINATED; NEURAL PATHWAYS; PROSPECTIVE STUDIES; PSYCHOMOTOR PERFORMANCE; SEX CHARACTERISTICS;

EID: 77954077387     PISSN: 01456008     EISSN: 15300277     Source Type: Journal    
DOI: 10.1111/j.1530-0277.2010.01197.x     Document Type: Article

References (92)

1. Agartz I, Momenan R, Rawlings RR, Kerich MJ, Hommer DW (1999) Hippocampal volume in patients with alcohol dependence. Arch Gen Psychiatry 56 : 356 363.
2. Alling C, Bostrom K (1980) Demyelination of the mamillary bodies in alcoholism. A combined morphological and biochemical study. Acta Neuropathol (Berl) 50 : 77 80.
3. Badsberg-Jensen G, Pakkenberg B (1993) Do alcoholics drink their neurons away? Lancet 342 : 1201 1204.
4. Basser PJ, Pierpaoli C (1996) Microstructural and physiological features of tissues elucidated by quantitative diffusion tensor MRI. J Magn Reson B 111 : 209 219.
5. Beck AT, Steer RA, Brown GK (1996) Manual for the Beck Depression Inventory-II. Psychological Corporation
6. Cardenas VA, Studholme C, Meyerhoff DJ, Song E, Weiner MW (2005) Chronic active heavy drinking and family history of problem drinking modulate regional brain tissue volumes. Psychiatry Res 138 : 115 130.
7. Chanraud S, Martelli C, Delain F, Kostogianni N, Douaud G, Aubin HJ, Reynaud M, Martinot JL (2007) Brain morphometry and cognitive performance in detoxified alcohol-dependents with preserved psychosocial functioning. Neuropsychopharmacology 32 : 429 438.
8. Courville CB (1955) Effects of Alcohol on the Nervous System of Man. San Lucas Press
9. Crovitz HF, Zener KA (1962) Group test for assessing hand and eye dominance. Am J Psychol 75 : 271 276.
10. De la Monte SM (1988) Disproportionate atrophy of cerebral white matter in chronic alcoholics. Arch Neurol 45 : 990 992.
11. Durazzo TC, Cardenas VA, Studholme C, Weiner MW, Meyerhoff DJ (2007) Non-treatment-seeking heavy drinkers: effects of chronic cigarette smoking on brain structure. Drug Alcohol Depend 87 : 76 82.
12. Endicott J, Spitzer RL, Fleiss JL, Cohen J (1976) The global assessment scale. A procedure for measuring overall severity of psychiatric disturbance. Arch Gen Psychiatry 33 : 766 771.
13. Estruch R, Nicolas JM, Salamero M, Aragon C, Sacanella E, Fernandez-Sola J, Urbano-Marquez A (1997) Atrophy of the corpus callosum in chronic alcoholism. J Neurol Sci 146 : 145 151.
14. Fama R, Eisen JC, Rosenbloom MJ, Sassoon SA, Kemper CA, Deresinski S, Pfefferbaum A, Sullivan EV (2007) Upper and lower limb motor impairments in alcoholism, HIV infection, and their comorbidity. Alcohol Clin Exp Res 31 : 1038 1044.
15. Fama R, Rosenbloom MJ, Nichols BN, Pfefferbaum A, Sullivan EV (2009) Working and episodic memory in HIV infection, alcoholism, and their comorbidity: baseline and 1-year follow-up examinations. Alcohol Clin Exp Res 33 : 1815 1824.
16. Fein G, Di SclafaniV, Cardenas VA, Goldmann H, Tolou-Shams M, Meyerhoff DJ (2002) Cortical gray matter loss in treatment-naive alcohol dependent individuals. Alcohol Clin Exp Res 26 : 558 564.
17. Fein G, Torres J, Price LJ, Di Sclafani V (2006) Cognitive performance in long-term abstinent alcoholic individuals. Alcohol Clin Exp Res 30 : 1538 1544.
18. First MB, Spitzer RL, Gibbon M, Williams JBW (1998) Structured Clinical Interview for DSM-IV Axis I Disorders (SCID) Version 2.0. Biometrics Research Department
19. Fregly AR, Graybiel A, Smith MS (1972) Walk on floor eyes closed (WOFEC): a new addition to an ataxia test battery. Aerosp Med 43 : 395 399.
20. Gazdzinski S, Durazzo TC, Studholme C, Song E, Banys P, Meyerhoff DJ (2005) Quantitative brain MRI in alcohol dependence: preliminary evidence for effects of concurrent chronic cigarette smoking on regional brain volumes. Alcohol Clin Exp Res 29 : 1484 1495.
21. Gerig G, Corouge I, Vachet C, Krishnan KR, MacFall JR (2005) Quantitative analysis of diffusion properties of white matter fiber tracts: a validation study. Paper presented at the 13th Proceedings of the International Society for Magnetic Resonance in Medicine, Miami, FL.
22. Glosser G, Butters N, Kaplan E (1977) Visuoperceptual processes in brain damaged patients on the digit symbol substitution test. Int J Neurosci 7 : 59 66.
23. Harper C, Dixon G, Sheedy D, Garrick T (2003) Neuropathological alterations in alcoholic brains. Studies arising from the New South Wales Tissue Resource Centre. Prog Neuropsychopharmacol Biol Psychiatry 27 : 951 961.
24. Harper C, Kril J (1991) If you drink your brain will shrink: neuropathological considerations. Alcohol Alcohol Suppl 1 : 375 380.
25. Harper CG, Kril JJ (1993) Neuropathological changes in alcoholics, in Alcohol Induced Brain Damage: NIAAA Research Monograph No. 22 (Hunt WA, Nixon SJ eds pp. 39 69. National Institute of Health
26. Hollingshead AB, Redlich FC (1958) Social Class and Mental Illness. John Wiley and Sons
27. Hommer DW, Momenan R, Kaiser E, Rawlings RR (2001) Evidence for a gender-related effect of alcoholism on brain volumes. Am J Psychiatry 158 : 198 204.
28. Hommer D, Momenan R, Rawlings R, Ragan P, Williams W, Rio D, Eckardt M (1996) Decreased corpus callosum size among alcoholic women. Arch Neurol 53 : 359 363.
29. Jernigan TL, Butters N, DiTraglia G, Schafer K, Smith T, Irwin M, Grant I, Schuckit M, Cermak L (1991) Reduced cerebral grey matter observed in alcoholics using magnetic resonance imaging. Alcohol Clin Exp Res 15 : 418 427.
30. Joy S, Fein D, Kaplan E (2003) Decoding digit symbol: speed, memory, and visual scanning. Assessment 10 : 56 65.
31. Kril JJ, Halliday GM, Svoboda MD, Cartwright H (1997) The cerebral cortex is damaged in chronic alcoholics. Neuroscience 79 : 983 998.
32. Lancaster FE (1993) Ethanol and white matter damage in the brain, in Alcohol-Induced Brain Damage: NIAAA Research Monograph No. 22 (Hunt WA, Nixon SJ eds pp. 387 399. National Institute of Health
33. Learned-Miller EG (2006) Data driven image models through continuous joint alignment. IEEE Trans Pattern Anal Mach Intell 28 : 236 250.
34. Lehericy S, Ducros M, Van de Moortele PF, Francois C, Thivard L, Poupon C, Swindale N, Ugurbil K, Kim DS (2004) Diffusion tensor fiber tracking shows distinct corticostriatal circuits in humans. Ann Neurol 55 : 522 529. (Pubitemid 38391969)
35. Lewohl J, Wang L, Miles M, Zhang L, Dodd P, Harris R (2000) Gene expression in human alcoholism: microarray analysis of frontal cortex. Alcohol Clin Exp Res 24 : 1873 1882.
36. Ma N, Li L, Shu N, Liu J, Gong G, He Z, Li Z, Tan L, Stone WS, Zhang Z, Xu L, Jiang T (2007) White matter abnormalities in first-episode, treatment-naive young adults with major depressive disorder. Am J Psychiatry 164 : 823 826. (Pubitemid 46808539)
37. Mann KF, Ackermann K, Croissan B, Mundle G, Diehl A (2005) Neuroimaging of gender differences in alcoholism: are women more vulnerable? Alcohol Clin Exp Res 29 : 896 901.
38. Mayfield RD, Lewohl JM, Dodd PR, Herlihy A, Liu J, Harris RA (2002) Patterns of gene expression are altered in the frontal and motor cortices of human alcoholics. J Neurochem 81 : 802 813.
39. Mori S, Crain BJ, Chacko VP, van ZijlPC (1999) Three-dimensional tracking of axonal projections in the brain by magnetic resonance imaging. Ann Neurol 45 : 265 269.
40. Neeman M, Freyer JP, Sillerud LO (1991) A simple method for obtaining cross-term-free images for diffusion anisotropy studies in NMR microimaging. Magn Reson Med 21 : 138 143.
41. Nixon SJ, Tivis R, Ceballos N, Varner JL, Rohrbaugh J (2002) Neurophysiological efficiency in male and female alcoholics. Prog Neuropsychopharmacol Biol Psychiatry 26 : 919 927.
42. Oscar-Berman M, Marinkovic K (2007) Alcohol: effects on neurobehavioral functions and the brain. Neuropsychol Rev 17 : 239 257.
43. Pandya DN, Seltzer B (1986) The topography of commissural fibers, in Two Hemispheres-One Brain: Functions of the Corpus Callosum (Lepore F, Ptito M, Jasper HH eds pp. 47 74. Alan R. Liss
44. Paula-Barbosa MM, Tavares MA (1985) Long term alcohol consumption induces microtubular changes in the adult rat cerebellar cortex. Brain Res 339 : 195 199.
45. Pfefferbaum A, Adalsteinsson E, Sullivan EV (2003) Replicability of diffusion tensor imaging measurements of fractional anisotropy and trace in brain. J Magn Reson Imaging 18 : 427 433.
46. Pfefferbaum A, Adalsteinsson E, Sullivan EV (2006a) Dysmorphology and microstructural degradation of the corpus callosum: interaction of age and alcoholism. Neurobiol Aging 27 : 994 1009.
47. Pfefferbaum A, Adalsteinsson E, Sullivan EV (2006b) Supratentorial profile of white matter microstructural integrity in recovering alcoholic men and women. Biol Psychiatry 59 : 364 372.
48. Pfefferbaum A, Lim KO, Desmond JE, Sullivan EV (1996) Thinning of the corpus callosum in older alcoholic men: a magnetic resonance imaging study. Alcohol Clin Exp Res 20 : 752 757.
49. Pfefferbaum A, Lim KO, Zipursky RB, Mathalon DH, Rosenbloom MJ, Lane B, Ha CN, Sullivan EV (1992) Brain gray and white matter volume loss accelerates with aging in chronic alcoholics: a quantitative MRI study. Alcohol Clin Exp Res 16 : 1078 1089.
50. Pfefferbaum A, Rosenbloom MJ, Adalsteinsson E, Sullivan EV (2007) Diffusion tensor imaging with quantitative fiber tracking in HIV infection and alcoholism comorbidity: synergistic white matter damage. Brain 130 : 48 64.
51. Pfefferbaum A, Rosenbloom MJ, Deshmukh A, Sullivan EV (2001) Sex differences in the effects of alcohol on brain structure. Am J Psychiatry 158 : 188 197.
52. Pfefferbaum A, Rosenbloom MJ, Rohlfing T, Adalsteinsson E, Kemper CA, Deresinski S, Sullivan EV (2006c) Contribution of alcoholism to brain dysmorphology in HIV infection: effects on the ventricles and corpus callosum. Neuroimage 33 : 239 251.
53. Pfefferbaum A, Rosenbloom MJ, Rohlfing T, Sullivan EV (2009) Degradation of association and projection white matter systems in alcoholism detected with quantitative fiber tracking. Biol Psychiatry 65 : 680 690.
54. Pfefferbaum A, Rosenbloom M, Serventi KL, Sullivan EV (2002) Corpus callosum, pons, and cortical white matter in alcoholic women. Alcohol Clin Exp Res 26 : 400 406.
55. Pfefferbaum A, Sullivan EV (2002) Microstructural but not macrostructural disruption of white matter in women with chronic alcoholism. Neuroimage 15 : 708 718.
56. Pfefferbaum A, Sullivan EV (2003) Increased brain white matter diffusivity in normal adult aging: relationship to anisotropy and partial voluming. Magn Reson Med 49 : 953 961.
57. Pfefferbaum A, Sullivan EV (2005) Disruption of brain white matter microstructure by excessive intracellular and extracellular fluid in alcoholism: evidence from diffusion tensor imaging. Neuropsychopharmacology 30 : 423 432.
58. Pfefferbaum A, Sullivan EV, Hedehus M, Adalsteinsson E, Lim KO, Moseley M (2000) In vivo detection and functional correlates of white matter microstructural disruption in chronic alcoholism. Alcohol Clin Exp Res 24 : 1214 1221.
59. Pierpaoli C, Barnett A, Pajevic S, Chen R, Penix L, Virta A, Basser PJ (2001) Water diffusion changes in Wallerian degeneration and their dependence on white matter architecture. Neuroimage 13 : 1174 1185.
60. Putzke J, De BeunR, Schreiber R, De Vry J, Tolle T, Zieglgansberger W, Spanagel R (1998) Long-term alcohol self-administration and alcohol withdrawal differentially modulate microtubule-associated protein 2 (MAP2) gene expression in the rat brain. Brain Res Mol Brain Res 62 : 196 205.
61. Rohlfing T, Brandt R, Maurer CR Jr., Menzel R (2001) Bee brains, B-splines and computational democracy: generating an average shape atlas, in IEEE Workshop on Mathematical Methods in Biomedical Image Analysis (Staib L, Kauai HI 187 194. IEEE Computer Society
62. Rohlfing T, Maurer CR (2003) Nonrigid image registration in shared-memory multiprocessor environments with application to brains, breasts, and bees. IEEE Trans Inf Technol Biomed 7 : 16 25.
63. Rosenbloom MJ, O'Reilly A, Sassoon SA, Sullivan EV, Pfefferbaum A (2005) Persistent cognitive deficits in community-treated alcoholic men and women volunteering for research: limited contribution from psychiatric comorbidity. J Stud Alcohol 66 : 254 265.
64. Rosenbloom MJ, Sassoon SA, Pfefferbaum A, Sullivan EV (2009) Contribution of regional white matter integrity to visuospatial construction accuracy, organizational strategy, and memory for a complex figure in abstinent alcoholics. Brain Imaging Behav 3 : 379 390.
65. Rosenbloom MJ, Sullivan EV, Sassoon SA, O'Reilly A, Fama R, Kemper CA, Deresinski SC, Pfefferbaum A (2007) Alcoholism, HIV infection and their comorbidity: factors affecting self-rated health-related quality of life. J Stud Alcohol Drugs 68 : 115 125.
66. Rueckert D, Sonoda LI, Hayes C, Hill DL, Leach MO, Hawkes DJ (1999) Nonrigid registration using free-form deformations: application to breast MR images. IEEE Trans Med Imaging 18 : 712 721. (Pubitemid 32262025)
67. Sassoon SA, Fama R, Rosenbloom MJ, O'Reilly A, Pfefferbaum A, Sullivan EV (2007) Component cognitive and motor processes of the digit symbol test: differential deficits in alcoholism, HIV infection, and their comorbidity. Alcohol Clin Exp Res 31 : 1315 1324.
68. Schulte T, Müller-Oehring EM, Pfefferbaum A, Sullivan EV (2008) Callosal compromise differentially affects conflict processing and attentional allocation in alcoholism, HIV infection, and their comorbidity. Brain Imaging Behav 2 : 27 38.
69. Schulte T, Müller-Oehring EM, Rosenbloom MJ, Pfefferbaum A, Sullivan EV (2005a) Differential effect of HIV infection and alcoholism on conflict processing, attentional allocation, and perceptual load: evidence from a Stroop match-to-sample task. Biol Psychiatry 57 : 67 75.
70. Schulte T, Sullivan EV, Müller-Oehring EM, Adalsteinsson E, Pfefferbaum A (2005b) Corpus callosal microstructural integrity influences interhemispheric processing: a diffusion tensor imaging study. Cereb Cortex 15 : 1384 1392.
71. Skinner HA (1982) Development and Validation of a Lifetime Alcohol Consumption Assessment Procedure. Addiction Research Foundation
72. Skinner HA, Sheu WJ (1982) Reliability of alcohol use indices: the lifetime drinking history and the MAST. J Stud Alcohol 43 : 1157 1170.
73. Smith S (2002) Fast robust automated brain extraction. Hum Brain Mapp 17 : 143 155.
74. Song SK, Sun SW, Ramsbottom MJ, Chang C, Russell J, Cross AH (2002) Dysmyelination revealed through MRI as increased radial (but unchanged axial) diffusion of water. Neuroimage 17 : 1429 1436.
75. Song SK, Yoshino J, Le TQ, Lin SJ, Sun SW, Cross AH, Armstrong RC (2005) Demyelination increases radial diffusivity in corpus callosum of mouse brain. Neuroimage 26 : 132 140.
76. Stieltjes B, Kaufmann WE, van Zijl PC, Fredericksen K, Pearlson GD, Solaiyappan M, Mori S (2001) Diffusion tensor imaging and axonal tracking in the human brainstem. Neuroimage 14 : 723 735.
77. Sullivan EV, Adalsteinsson E, Pfefferbaum A (2006) Selective age-related degradation of anterior callosal fiber bundles quantified in vivo with fiber tracking. Cereb Cortex 16 : 1030 1039.
78. Sullivan EV, Deshmukh A, Desmond JE, Lim KO, Pfefferbaum A (2000a) Cerebellar volume decline in normal aging, alcoholism, and Korsakoff's syndrome: relation to ataxia. Neuropsychology 14 : 341 352.
79. Sullivan EV, Fama R, Rosenbloom MJ, Pfefferbaum A (2002) A profile of neuropsychological deficits in alcoholic women. Neuropsychology 16 : 74 83.
80. Sullivan EV, Rohlfing T, Pfefferbaum A (2010a) Longitudinal study of callosal microstructure in the normal adult aging brain using quantitative DTI fiber tracking. Dev Neuropsychol (in press).
81. Sullivan EV, Rohlfing T, Pfefferbaum A (2010b) Pontocerebellar volume deficits and ataxia in alcoholic men and women: no evidence for "telescoping". Psychopharmacology 208 : 279 290.
82. Sullivan EV, Rohlfing T, Pfefferbaum A (2010c) Quantitative fiber tracking of lateral and interhemispheric white matter systems in normal aging: relations to timed performance. Neurobiol Aging 31 : 464 481.
83. Sullivan EV, Rosenbloom MJ, Pfefferbaum A (2000b) Pattern of motor and cognitive deficits in detoxified alcoholic men. Alcohol Clin Exp Res 24 : 611 621.
84. Sun SW, Liang HF, Le TQ, Armstrong RC, Cross AH, Song SK (2006a) Differential sensitivity of in vivo and ex vivo diffusion tensor imaging to evolving optic nerve injury in mice with retinal ischemia. Neuroimage 32 : 1195 1204.
85. Sun SW, Liang HF, Trinkaus K, Cross AH, Armstrong RC, Song SK (2006b) Noninvasive detection of cuprizone induced axonal damage and demyelination in the mouse corpus callosum. Magn Reson Med 55 : 302 308.
86. Tarnowska-Dziduszko E, Bertrand E, Szpak G (1995) Morphological changes in the corpus callosum in chronic alcoholism. Folia Neuropathol 33 : 25 29.
87. Wang JJ, Durazzo TC, Gazdzinski S, Yeh PH, Mon A, Meyerhoff DJ (2009) MRSI and DTI: a multimodal approach for improved detection of white matter abnormalities in alcohol and nicotine dependence. NMR Biomed 22 : 516 522.
88. Wechsler D (1981) Wechsler Adult Intelligence Scale - Revised. The Psychological Corporation
89. Wiggins RC, Gorman A, Rolsten C, Samorajski T, Ballinger WE, Freund G (1988) Effects of aging and alcohol on the biochemical composition of histologically normal human brain. Metab Brain Dis 3 : 67 80.
90. Woods RP, Grafton ST, Holmes CJ, Cherry SR, Mazziotta JC (1998) Automated image registration: I. General methods and intrasubject, intramodality validation. J Comput Assist Tomogr 22 : 139 152.
91. Xu D, Mori S, Solaiyappan M, van Zijl PC, Davatzikos C (2002) A framework for callosal fiber distribution analysis. Neuroimage 17 : 1131 1143.
92. Zanetti MV, Jackowski MP, Versace A, Almeida JR, Hassel S, Duran FL, Busatto GF, Kupfer DJ, Phillips ML (2009) State-dependent microstructural white matter changes in bipolar I depression. Eur Arch Psychiatry Clin Neurosci 259 : 316 328.