Long-term alcohol self-administration and alcohol withdrawal differentially modulate microtubule-associated protein 2 (MAP2) gene expression in the rat brain

Molecular Brain Research

Volumn 62, Issue 2, 1998, Pages 196-205

  Putzke, Jörg ^a,d   De Beun, René ^c   Schreiber, Rudy ^b   De Vry, Jean ^b   Tölle, Thomas R ^e   Zieglgänsberger, Walter ^a   Spanagel, Rainer ^a  

^a MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

^b MEDA Manufacturing GmbH   (Germany)

^c NOVO NORDISK A S   (Denmark)

^d OTTO VON GUERICKE UNIVERSITY   (Germany)

^e NONE

Author keywords

Alcohol; Dot blot hybridization; Ethanol; Extrapyramidal system; HMW MAP2; In situ hybridization; Neurotoxicity; Northern; Withdrawal

Indexed keywords

MESSENGER RNA; MICROTUBULE ASSOCIATED PROTEIN 2;

ALCOHOL ABUSE; ALCOHOL CONSUMPTION; ALCOHOL INTOXICATION; ALCOHOL WITHDRAWAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CAUDATE NUCLEUS; CONTROLLED STUDY; GLOBUS PALLIDUS; IN SITU HYBRIDIZATION; MALE; NEUROTOXICITY; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN DETERMINATION; PUTAMEN; RAT; RNA ANALYSIS; SUBSTANTIA NIGRA;

ALCOHOL WITHDRAWAL DELIRIUM; ALCOHOLISM; ANIMALS; BRAIN; BRAIN CHEMISTRY; CYTOSKELETON; ETHANOL; GENE EXPRESSION REGULATION; IN SITU HYBRIDIZATION; MALE; MICROTUBULE-ASSOCIATED PROTEINS; MOTOR CORTEX; NERVE TISSUE PROTEINS; NEURONS; ORGAN SPECIFICITY; RATS; RATS, WISTAR; RNA, MESSENGER; SUBSTANCE WITHDRAWAL SYNDROME;

EID: 0032569937     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(98)00253-8     Document Type: Article

References (43)

1. Arias C., Sharma N., Davies P., Shafit-Zagardo B. Okadaic acid induces early changes in microtubule-associated protein 2 and phosphorylation prior to neurodegeneration in cultured cortical neurons. J. Neurochem. 61:1993;673-682.
2. Chauhan N.B., Spencer P.S., Sabri M.I. Acrylamide-induced depletion of microtubule-associated proteins (MAP1 and MAP2) in the rat extrapyramidal system. Brain Res. 602:1993;111-118.
3. De Beun R., Schneider R., Klein A., Lohmann A., Schreiber R., De Vry J. The calcium channel agonist BAY K 8644 reduces ethanol intake and preference in alcohol-preferring AA rats. Psychopharmacology. 127:1996;302-310.
4. Eriksson K. Genetic selection for voluntary alcohol consumption in the albino rat. Science. 159:1968;739-741.
5. Fifkova E., Eason H., Bueltman K., Joo J., Morales M. Changes in brain actin and tubulin following chronic ethanol treatment. Soc. Neurosci. Abstr. 21:1995;1242.
6. Froehlich J.C., Li T.K. Opioid involvement in alcohol drinking. Ann. NY Acad. Sci. 343:1995;156-167.
7. Garner C.C., Matus A. Different forms of microtubule-associated protein 2 are encoded by separate mRNA transcripts. J. Cell Biol. 106:1988;779-783.
8. Garner C.C., Tucker R.P., Matus A. Selective localization of messenger RNA for cytoskeletal protein MAP2 in dendrites. Nature. 336:1988;674-677.
9. Geddes J.W., Bondada V., Keller J.N. Effects of intrahippocampal colchicine administration on the levels and localization of microtubule-associated proteins, tau and MAP2. Brain Res. 633:1994;1-8.
10. Goedert M., Crowther R.A., Garner C.C. Molecular characterization of microtubule-associated proteins tau and MAP2. Trends in Neurosci. 14:1991;193-199.
11. Guitart X., Lumeng L., Li T.K., Nestler E.J. Alcohol-preferring and nonpreferring rats display different levels of neurofilament proteins in the ventral tegmental area. Alcohol. Clin. Exp. Res. 17:1993;580-586.
12. S.M. Hölter, M. Engelmann, C. Kirschke, G. Liebsch, R. Landgraf, R. Spanagel, Long-term ethanol self-administration with repeated ethanol deprivation episodes changes ethanol drinking pattern and increases anxiety-related behavior during ethanol deprivation in rats, Behav. Pharmcol., 9, 1998 in press.
13. Izant J.G., McIntosh J.R. Microtubule-associated proteins: a monoclonal antibody to MAP2 binds to differentiated neurons. Proc. Natl. Acad. Sci. USA. 77:1980;4741-4745.
14. Johnston H.M., Morris B.J. NMDA and nitric oxide increase microtubule-associated protein 2 gene expression in hippocampal granule cells. J. Neurochem. 63:1994;379-382.
15. Kikuchi S., Kim S.U. Glutamate neurotoxicity in mesencephalic dopaminergic neurons in culture. J. Neurosci. Res. 36:1993;558-569.
16. Kindler S., Schwanke B., Schulz B., Garner C.C. Complete cDNA sequence encoding rat high and low molecular weight MAP2. Nucl. Acid. Res. 18:1990;222-228.
17. Kindler S., Schulz B., Goedert M., Garner C.C. Molecular structure of microtubule-associated protein 2b and 2c from rat brain. J. Biol. Chem. 265:1990;19679-19684.
18. Kitagawa K., Matsumoto M., Niinobe M., Mikoshiba K., Hata R., Ueda H., Handa N., Fukunaga R., Isaka Y., Kimura K., Kamada T. Microtubule-associated protein 2 as a sensitive marker for cerebral ischemic damage - immunohistochemical investigation of dendritic damage. Neuroscience. 31:1989;401-411.
19. Kwei S., Jiang C., Haddad G.G. Acute anoxia-induced alterations in MAP2 immunoreactivity and neuronal morphology in rat hippocampus. Brain Res. 620:1993;203-210.
20. Lang D., Fifkova E., Beno M. Dendritic microtubules in the dentate fascia are affected by chronic ethanol exposure. Soc. Neurosci. Abstr. 21:1995;1242.
21. Mackler S.A., Eberwine J.H. The molecular biology of addictive drugs. Mol. Neurobiol. 5:1991;45-48.
22. Matus A. Stiff microtubules and neuronal morphology. Trends in Neurosci. 17:1994;19-22.
23. Mazumdar M., Parrack P.K., Mukhopadhyay K., Bhattacharyya B. Bis-ANS as a specific inhibitor for microtubule-associated protein induced assembly of tubulin. Biochemistry. 31:1992;6470-6474.
24. McLane J.A. Decreased axonal transport in rat nerve following acute and chronic ethanol exposure. Alcohol. 4:1987;385-389.
25. Nevo I., Hamon M. Neurotransmitter and neuromodulatory mechanisms involved in alcohol abuse and alcoholism. Neurochem. Int. 26:1995;305-336.
26. Opitz K. The effect of clonidine and related substances on voluntary ethanol consumption in rats. Drug Alcohol Depend. 25:1990;43-48.
27. Ortiz J., Fitzgerald L.W., Charlton M., Lane S., Trevisan L., Guitart X., Shoemaker W., Duman R.S., Nestler E.J. Biochemical actions of chronic ethanol exposure in the mesolimbic dopamine system. Synapse. 21:1995;289-298.
28. Papandrikopoulou A., Doll T., Tucker R.P., Garner C.C., Matus A. Embryonic MAP2 lacks the crosslinking sidearm sequences and dendritic targeting signal of adult MAP2. Nature. 340:1989;650-652.
29. G. Paxinos, C. Watson, The Rat Brain in Stereotaxic Coordinates, 2nd edn., Academic Press, Sydney, 1986.
30. Putzke J., Spanagel R., Tölle T.R., Zieglgänsberger W. The anti-craving drug acamprosate reduces c-fos expression in rats undergoing ethanol withdrawal. Eur. J. Pharmacol. 317:1996;39-48.
31. Riley J.N., Walker D. Morphological alterations in hippocampus after long-term alcohol consumption in mice. Science. 201:1978;646-648.
32. Schreiber R., Opitz K., Glaser T., De Vry J. Ipsapirone and 8-OH-DPAT reduce ethanol preference in rats: involvement of presynaptic 5-HT1A receptors. Psychopharmacology. 112:1993;100-110.
33. Spanagel R., Hölter S.M., Allingham K., Landgraf R., Zieglgänsberger W. Acamprosate and alcohol: I. Effects on alcohol intake following alcohol deprivation in the rat. Eur. J. Pharmacol. 305:1996;39-44.
34. Stratton K.R., Worley P.F., Litz J.S., Parsons S.J., Huganir R.L., Baraban J.M. Electroconvulsive treatment induces a rapid and transient increase in tyrosine phosphorylation of a 40-kilodalton protein associated with microtubule-associated protein 2 kinase activity. J. Neurochem. 56:1991;147-152.
35. Taft W.C., Yang K., Dixon C.E., Hayes R.L. Microtubule-associated protein 2 levels decrease in hippocampus following traumatic brain injury. J. Neurotrauma. 9:1992;281-290.
36. Tucker R.P. The roles of microtubule-associated proteins in brain morphogenesis: a review. Brain Res. Rev. 15:1990;101-120.
37. Tucker R.P., Garner C.C., Matus A. In situ localization of microtubule-associated protein mRNA in the developing and adult rat brain. Neuron. 2:1989;1245-1256.
38. Tuma D.J., Smith S.L., Sorrell M.F. Acetaldehyde and microtubules. Ann. NY Acad. Sci. 625:1991;786-792.
39. Vanicky I., Balchen T., Diemer N.H. Alterations in MAP2 immuno-stainability after prolonged complete brain ischaemia in the rat. NeuroReport. 7:1995;161-164.
40. Viereck C., Tucker R.P., Matus A. The adult rat olfactory system expresses microtubule-associated proteins found in the developing brain. J. Neurosci. 9:1989;3547-3557.
41. Weisshaar B., Matus A. Microtubule-associated protein 2 and the organization of cellular microtubules. J. Neurocyt. 22:1992;727-734.
42. Whitaker-Azmitia P.M., Borella A., Raio N. Serotonin depletion in the adult rat causes loss of the dentritic marker MAP-2. Neuropsychopharmacology. 12:1995;269-272.
43. Yanagihara T., Brengman J.M., Mushynski W.E. Differential vulnerability of microtubule components in cerebral ischemia. Acta Neuropathol. 80:1990;499-505.