Quantifying the relative amount of mouse and human DNA in cancer xenografts using species-specific variation in gene length

BioTechniques

Volumn 48, Issue 3, 2010, Pages 351-355

  Lin, Ming Tseh ^a   Tseng, Li Hui ^a,b   Kamiyama, Hirohiko ^a   Kamiyama, Mihoko ^a   Lim, Phillip ^a   Hidalgo, Manuel ^a   Wheelan, Sarah ^a   Eshleman, James R ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Capillary gel electrophoresis; Chimerism; Quantification; Species specific length variation; Xenograft

Indexed keywords

ARTICLE; CANCER CELL CULTURE; CAPILLARY ELECTROPHORESIS; CHROMOSOME 10; CHROMOSOME 9; CONTAMINATION; DNA SEQUENCE; GENE DELETION; GENE INSERTION; GENE LENGTH; GENE LOCUS; GENETIC VARIABILITY; GENOME ANALYSIS; HUMAN; HUMAN CELL; MOUSE; MULTIPLEX POLYMERASE CHAIN REACTION; NONHUMAN; PANCREAS CANCER; PARAMETER; QUANTITATIVE ASSAY; SPECIES DIFFERENCE; TUMOR XENOGRAFT; ANIMAL; CANCER TRANSPLANTATION; CHROMOSOME MAP; GENETIC POLYMORPHISM; GENETICS; GENOME; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PANCREAS TUMOR; PATHOLOGY; POLYMERASE CHAIN REACTION; REPRODUCIBILITY; XENOGRAFT;

MUS;

DNA;

ANIMALS; BASE SEQUENCE; CHROMOSOME MAPPING; DNA; ELECTROPHORESIS, CAPILLARY; GENOME; HUMANS; MICE; MOLECULAR SEQUENCE DATA; NEOPLASM TRANSPLANTATION; PANCREATIC NEOPLASMS; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; REPRODUCIBILITY OF RESULTS; SEQUENCE ANALYSIS, DNA; SPECIES SPECIFICITY; TRANSPLANTATION, HETEROLOGOUS;

EID: 77954064103     PISSN: 07366205     EISSN: None     Source Type: Journal    
DOI: 10.2144/000113363     Document Type: Article

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