Exposure-response of 1,2:3,4-diepoxybutane-specific N-terminal valine adducts in mice and rats after inhalation exposure to 1,3-butadiene

Toxicological Sciences

Volumn 115, Issue 2, 2010, Pages 322-329

  Georgieva, Nadia I ^a   Boysen, Gunnar ^a,b   Bordeerat, Narisa ^a   Walker, Vernon E ^c,d   Swenberg, James A ^a,b  

^a IL   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^c Lovelace Resp Research Institute   (Mexico)

^d UNIVERSITY OF VERMONT   (United States)

Author keywords

Butadiene diepoxide; Molecular dosimetry; N terminal valine adducts

Indexed keywords

1,3 BUTADIENE; BUTADIENE DIEPOXIDE; VALINE;

ANIMAL EXPERIMENT; ARTICLE; CARCINOGENICITY; CELL SURVIVAL; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; ERYTHROCYTE LIFESPAN; FEMALE; GENE MUTATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; RAT; TANDEM MASS SPECTROMETRY;

ANIMALS; BUTADIENES; CARCINOGENS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA ADDUCTS; EPOXY COMPOUNDS; FEMALE; INHALATION EXPOSURE; MALE; MICE; MICE, INBRED STRAINS; PYRROLIDINES; RATS; RATS, INBRED F344; SPECIES SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY; VALINE;

MUS; RATTUS; RODENTIA;

EID: 77954058701     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfq060     Document Type: Article

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