A new highly versatile handle for chemistry on a solid support: The pipecolic linker

Chemistry - A European Journal

Volumn 16, Issue 25, 2010, Pages 7547-7553

  Zajdel, Paweł ^a,b   Nomezine, Gaël ^a   Masurier, Nicolas ^a   Amblard, Muriel ^a   Pawłowski, Maciej ^b   Martinez, Jean ^a   Subra, Gilles ^a  

^a UNIVERSITÉ DE MONTPELLIER   (France)

^b JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

Author keywords

Amino acids; C terminal modification; Hydrazides; Pipecolic linkers; Solid phase synthesis

Indexed keywords

ACIDIC TREATMENT; AROMATIC AMINES; C TERMINUS; HIGH PURITY; HYDRAZIDES; PEPTIDE CHEMISTRIES; PEPTIDOMIMETICS; POTENTIAL APPLICATIONS; SMALL ORGANIC MOLECULES; SOLID PHASE SYNTHESIS; SOLID SUPPORTS; TERMINAL MODIFICATIONS;

AMINES; AMINO ACIDS; ORGANIC ACIDS; PEPTIDES; PHENOLS; RESINS;

AMINATION;

AMINE; HYDRAZINE DERIVATIVE; PEPTIDE; PIPECOLIC ACID DERIVATIVE;

ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; MOLECULAR GENETICS; X RAY CRYSTALLOGRAPHY;

AMINES; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; HYDRAZINES; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; PEPTIDES; PIPECOLIC ACIDS;

EID: 77954047156     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.201000313     Document Type: Article

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31. 4% of hydrazone formed with acetone was detected by LC/MS.
32. Other curves are presented in the Supporting Information.