Mechanistic studies of amide bond scission during acidolytic deprotection of Pip containing peptide

Journal of Peptide Science

Volumn 14, Issue 8, 2008, Pages 989-997

  Rubini, Chiara ^a   Osler, Alessio ^a   Calderan, Andrea ^a   Guiotto, Andrea ^a   Ruzza, Paolo ^a  

^a CNR   (Italy)

Author keywords

Peptide degradation; Pipecolic acid; SH3 domain; TFA cleavage

Indexed keywords

AMIDE; OXAZOLINE DERIVATIVE; PEPTIDE DERIVATIVE; PIPECOLIC ACID; TRIFLUOROACETIC ACID;

ARTICLE; CHEMICAL BINDING; DEGRADATION; ELECTROSPRAY MASS SPECTROMETRY; HYDROLYSIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PEPTIDE SYNTHESIS; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN STRUCTURE;

AMIDES; BINDING SITES; CHEMISTRY, PHYSICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEUTERIUM EXCHANGE MEASUREMENT; HYDROLYSIS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR CONFORMATION; PEPTIDES; PIPECOLIC ACIDS; REFERENCE STANDARDS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STEREOISOMERISM; TRIFLUOROACETIC ACID;

EID: 50449104527     PISSN: 10752617     EISSN: 10991387     Source Type: Journal    
DOI: 10.1002/psc.1032     Document Type: Article

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