Fragmented coronoid process in the dog: A heritable disease

Veterinary Journal

Volumn 185, Issue 2, 2010, Pages 123-129

  Temwichitr, Jedee ^a   Leegwater, Peter A J ^a   Hazewinkel, Herman A W ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Dog; Fragmented coronoid process; Genetics; Osteoarthritis; Pathogenesis

Indexed keywords

COLLAGEN;

BIOMECHANICS; BONE MALFORMATION; DISEASE ASSOCIATION; DOG; DOG DISEASE; ELBOW DISEASE; ELBOW JOINT DEVELOPMENT; ENCHONDRAL OSSIFICATION; FRAGMENTED CORONOID PROCESS; GENE EXPRESSION; GENE FUNCTION; GENE LOCATION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; HAPLOTYPE; HERITABILITY; INCIDENCE; LIMB DEVELOPMENT; LINKAGE ANALYSIS; LOAD CARRYING CAPACITY; MICROSATELLITE MARKER; MUSCULOSKELETAL FUNCTION; MUTATIONAL ANALYSIS; NONHUMAN; OSTEOSCLEROSIS; PATHOGENESIS; PHENOTYPE; PRESSURE MEASUREMENT; REVIEW; SHEAR STRESS; SINGLE NUCLEOTIDE POLYMORPHISM; ANIMAL; ANIMAL LAMENESS; ARTHROPATHY; FEMALE; FORELIMB; GENETIC LINKAGE; GENETICS; JOINT; MALE; OSTEOARTHRITIS; PATHOPHYSIOLOGY; PEDIGREE; VETERINARY;

ANIMALS; DOG DISEASES; DOGS; FEMALE; FORELIMB; JOINT DISEASES; JOINTS; LAMENESS, ANIMAL; LINKAGE (GENETICS); MALE; OSTEOARTHRITIS; PEDIGREE; GENETIC LINKAGE;

CANIS FAMILIARIS;

EID: 77954033927     PISSN: 10900233     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tvjl.2009.06.022     Document Type: Review

References (67)

1. Anderson A.C. Skeletal system chapter 9. The Beagle as an Experimental Dog 1970, 149-158. Iowa State University Press, Ames, Iowa, USA. A.C. Andersen (Ed.).
2. Beckman J.S., Weber J.L. Survey of human and rat microsatellites. Genomics 1992, 12:627-631.
3. Breit S., Künzel W., Seiler S. Variation in the ossification process of the anconeal and medial coronoid processes of the canine ulna. Research in Veterinary Sciences 2004, 77:9-16.
4. Burton N.J., Comerford E.J., Bailey M., Pead M.J., Owen M.R. Digital analysis of ulnar trochlear notch sclerosis in Labrador retrievers. Journal of Small Animal Practice 2007, 48:220-224.
5. Burton N.J., Dobney J.A., Owen M.R., Colborne G.R. Joint angle, moment and power compensations in dogs with fragmented medial coronoid process. Veterinary and Comparative Orthopaedics and Traumatology 2008, 21:110-118.
6. Carpenter L.G., Schwarz P.D., Lowry J.E., Park R.D., Steyn P.F. Comparison of radiographic imaging techniques for diagnosis of fragmented medial coronoid process of the cubital joint in dogs. Journal of the American Veterinary Medical Association 1993, 203:78-83.
7. Collins K.E., Cross A.R., Lewis D.D., Zapata J.L., Goett S.D., Newell S.M., Rapoff A.J. Comparison of the radius of curvature of the ulnar trochlear notch of Rottweilers and Greyhounds. American Journal of Veterinary Research 2001, 62:968-973.
8. Coopman F., Verhoeven G., Saunders J., Duchateau L., van Bree H. Prevalence of hip dysplasia, elbow dysplasia and humeral head osteochondrosis in dog breeds in Belgium. Veterinary Record 2008, 163:654-658.
9. Danielson K.C., Fitzpatrick N., Muir P., Manley P.A. Histomorphometry of fragmented medial coronoid process in dogs: a comparison of affected and normal coronoid process. Veterinary Surgery 2006, 35:501-509.
10. Dequeker J., Mokassa L., Aerssens J. Bone density and osteoarthritis. Journal of Rheumatology 1995, 43:93-100.
11. Eckstein F., Merz B., Schön M., Jacobs C.R., Putz R. Tension and bending, but not compression alone determine the functional adaptation of subchondral bone in incongruous joints. Anatomy and Embryology 1999, 199:85-97.
12. Ekman S., Carlson C.S. The pathophysiology of osteochondrosis. Veterinary Clinics of North America: Small Animal Practice 1998, 28:17-32.
13. Ellegren H. Microsatellites: simple sequences with complex evolution. Nature Review Genetics 2004, 5:435-445.
14. Evan R.B., Gordon-Evans W.J., Conzemius M.G. Comparison of three methods for the management of fragmented medial coronoid process in the dogs. A systematic review and meta-analysis. Veterinary Comparative Orthopaedics and Traumatology 2008, 21:106-109.
15. Everts, R.E., Meusissen, T.E., Ubbink, G.J., Hazewinkel, H.W., Wolvekamp, W.C., Rothuizen, J., van Oost, B.A., 2000. The inheritance of fragment coronoid process (FCP) in a Dutch population of Labrador Retriever dogs. In: Everts, R.E. (Ed.), Molecular Genetic Studies in the Dog: Application to Fragmented Coronoid Process (FCP) in the Labrador retriever. PhD Dissertation, Utrecht University, The Netherlands, pp. 31-42 (ISBN 90-6464-0262).
16. Eyre D.R. Collagen of articular cartilage. Arthritis Research 2002, 4:30-35.
17. Fitzpatrick N., Smith T.J., Evans R.B., Yeadon R. Radiographic and arthroscopic findings in the elbow joints of 263 dogs with medial coronoid disease. Veterinary Surgery 2009, 38:213-223.
18. Grøndalen J. Arthrosis in the elbow joint of young rapidly growing dogs. III. Ununited medical coronoid process of the ulna and osteochondritis dissecans of the humeral condyle. Surgical procedure for correction and postoperative investigation. Nordisk Veterinaermedicin 1979, 31:520-527.
19. Grøndalen J., Grøndalen T. Arthrosis in the elbow joint of young rapidly growing dogs. Nordisk Veterinaermedicin 1981, 33:1-16.
20. Grøndalen J., Lingaas F. Arthrosis in the elbow joint of young rapidly growing dogs: a genetic investigation. Journal of Small Animal Practice 1991, 32:460-464.
21. Guthrie S., Pidduck H.G. Heritability of elbow osteochondrosis within a closed population of dogs. Journal of Small Animal Practice 1990, 31:93-96.
22. Guthrie S., Plummer J.M., Vaughan L.C. Post natal development of the canine elbow joint: a light and electron microscopical study. Research in Veterinary Science 1992, 52:67-71.
23. Guthrie S., Plummer J.M., Vaughan L.C. Aetiopathogenesis of canine elbow osteochondrosis: a study of loose fragments removed at arthrotomy. Research in Veterinary Science 1992, 52:284-291.
24. Hazewinkel, H.A., Ubbink, G.J., 1999. Elbow dysplasia (ED) in the Dutch Bernese mountain dog population. In: Proceeding of the Thirteenth International Elbow Working Group, Orlando, Florida, USA.
25. Hazewinkel H.A., Voorhout G. Examination and treatment of a loose medial coronoid process in dogs. Tijdschrift voor Diergeneeskunde 1986, 111:1234-1245.
26. Hazewinkel H.A., Kantor A., Meij B., Voorhout G. Fragmented coronoid process and osteochondritis dissecans of the medial humeral condyle. Tijdschrift voor Diergeneeskunde 1988, 113:41S-46S.
27. Hirschhorn J.N., Daly M.J. Genome wide-association studies for common diseases and complex traits. Nature Reviews Genetics 2005, 6:95-109.
28. Houlton J.F. Osteochondrosis of the shoulder and elbow joints in dogs. Journal of Small Animal Practice 1984, 25:399-413.
29. Janutta V., Hamann H., Klein S., Tellhelm B., Distl O. Genetic analysis of three different classification protocols for the evaluation of elbow dysplasia in German shepherd dogs. Journal of Small Animal Practice 2006, 47:75-82.
30. Kirberger R.M., Stander N. Incidence of canine elbow dysplasia in South Africa. Journal of the South African Veterinary Association 2007, 78:59-62.
31. Kirkness E.F., Bafna V., Halpern A.L., Levy S., Remington K., Rusch D.B., Delcher A.L., Pop M., Wang W., Fraser C.M., Venter J.C. The dog genome: survey sequencing and comparative analysis. Science 2003, 301:1898-1903.
32. Kruglyak L., Daly M.J., Reeve-Daly M.P., Lander E.S. Parametric and nonparametric linkage analysis: a unified multipoint approach. American Journal of Human Genetics 1996, 58:1347-1363.
33. Künzel W., Breit S., Probst A. The subchondral split line patterns of the medial coronoid process in canine ulnae. Anatomia, Histologia, Embryologia 2004, 33:339-343.
34. LaFond E., Beur G.J., Austin C.C. Breed susceptibility for developmental orthopedic disease in dogs. Journal of the American Animal Hospital Association 2002, 38:467-477.
35. Mäki K., Janss L.L., Groen A.F., Liinamo A.E., Ojala M. An indication of major genes affecting hip and elbow dysplasia in four Finnish dog population. Heredity 2004, 92:402-408.
36. Malm S., Strandberg E., Danell B., Audell L., Swenson L., Hedhammar A. Impact of sedation method on the diagnosis of hip and elbow dysplasia in Swedish dogs. Preventive Veterinary Medicine 2007, 78:196-209.
37. Mason T.A., Lavelle R.B., Skipper S.C., Wrigley W.R. Osteochondrosis of the elbow joint in young dogs. Journal of Small Animal Practice 1980, 21:641-656.
38. Mason D.R., Schulz K.S., Fujita Y., Kass P.H., Stover S.M. In vitro force mapping of normal canine humeroradial and humeroulnar joints. American Journal of Veterinary Research 2005, 66:132-135.
39. Moores A.P., Benigni L., Lamb C.R. Computed tomography versus arthroscopy for detection of canine elbow dysplasia lesions. Veterinary Surgery 2008, 37:390-398.
40. Olsson S.-E. Osteochondrosis in the dog. Current Veterinary Therapy VI: Small Animal Practice 1977, 880-886. W.B. Saunders Co., Philadelphia. R.W. Kirk (Ed.).
41. Olsson D.E., Ekman S. Morphology and physiology of the growth cartilage under normal and pathological conditions. Bone in Clinical Orthopedics 2002, 117-155. Thieme, Stuttgart. G. Sumner-Smith (Ed.).
42. Parker H.G., Kim L.V., Sutter N.B., Carlson S., Lorentzen T.D., Malek T.B., Johnson G.S., DeFrance H.B., Ostrander E.A., Kruglyak L. Genetic structure of the purebred domestic dog. Science 2004, 304:1160-1164.
43. Patterson D.F. Companion animal medicine in the age of medical genetics. Journal of Veterinary Internal Medicine 2000, 14:1-9.
44. Presnel K.R. Surgery for fragmented medial coronoid process. Current Techniques in Small Animal Surgery 1990, 774-778. Lea & Febiger, Philadelphia. third ed. M.J. Bojrab (Ed.).
45. Preston C.A., Schulz K.S., Kass P.H. In vitro determination of contact areas in the normal elbow joint of dogs. American Journal of Veterinary Research 2000, 61:1315-1321.
46. Preston C.A., Schulz K.S., Taylor K.T. In vitro experiment study of the effect of radial shortening and ulnar ostectomy on contact patterns in the elbow joint of dogs. American Journal of Veterinary Research 2001, 62:1548-1556.
47. Remy D., Neuhart L., Fau D., Genevois J.P. Canine elbow dysplasia and primary lesions in German shepherd dogs in France. Journal of Small Animal Practice 2004, 45:244-248.
48. Roughley P.J. Age-associated changes in cartilage matrix: implications for tissue repair. Clinical Orthopaedics and Related Research 2001, 391:S153-S160.
49. Salg K.G., Temwitchitr J., Imholz S., Hazewinkel H.A., Leegwater P.A. Assessment of collagen genes involved in fragmented medial coronoid process development in Labrador Retrievers as determined by affected sibling-pair analysis. American Journal of Veterinary Research 2006, 67:1713-1718.
50. Samoy Y., Van Ryssen B., Gielen I., Walschot N., van Bree H. Review of the literature: elbow incongruity in the dog. Veterinary and Comparative Orthopaedics and Traumatology 2006, 19:1-8.
51. Snaps F.R., Balligand M.H., Saunders J.H., Park R.D., Dondelinger R.F. Comparison of radiography, magnetic resonance imaging, and surgical findings in dogs with elbow dysplasia. American Journal of Veterinary Research 1997, 58:1367-1370.
52. Studdert V.P., Lavelle R.B., Beiharz R.G., Mason T.A. Clinical features and heritability of osteochondrosis of the elbow in Labrador retrievers. Journal of Small Animal Practice 1991, 32:557-563.
53. Summerlee A.J. Bone formation and development. Bone in Clinical Orthopedics 2002, 1-5. Thieme, Stuttgart. G. Sumner-Smith (Ed.).
54. Swenson L., Audell L., Hedhammar A. Prevalence and inheritance of and selection for elbow arthrosis in Bernese Mountain dogs and Rottweilers in Sweden and benefit: cost analysis of a screening and control program. Journal of the American Veterinary Medical Association 1997, 210:215-221.
55. Temwichitr J., Hazewinkel H.A., van Hagen M.A., Leegwater P.A. Polymorphic microsatellite markers for genetic analysis of collagen genes in suspected collagenopathies in dogs. Journal of Veterinary Medicine A, Physiology, Pathology, Clinical medicine 2007, 54:522-526.
56. Theyse L.F., Hazewinkel H.A., Van den Brom W.E. Force plate analyses before and after surgical treatment of unilateral fragmented coronoid process. Veterinary and Comparative Orthopaedics and Traumatology 2000, 13:135-140.
57. Tirgari M. Clinical radiographical and pathological aspects of arthritis of the elbow joint in dogs. Journal of Small Animal Practice 1974, 15:671-679.
58. Tromblee T.C., Jones J.C., Bahr A.M., Shires P.K., Aref S. Effect of computed tomography display window and image plane on diagnostic certainty for characteristics of dysplastic elbow joints in dogs. American Journal of Veterinary Research 2007, 68:858-871.
59. Ubbink G.J., van de Broek J., Hazewinkel H.A., Rothuizen J. Cluster analysis of the genetic heterogeneity and disease distribution in purebred dog populations. Veterinary Record 1998, 142:209-213.
60. Ubbink G.J., Hazewinkel H.A., van de Broek J., Rothuizen J. Familial clustering and risk analysis for fragmented coronoid process and elbow joint incongruity in Bernese Mountain dogs in The Netherlands. American Journal of Veterinary Research 1999, 60:1082-1087.
61. Ubbink G., van de Broek J., Hazewinkel H.A., Wolvekamp W.T., Rothuizen J. Prediction of the genetic risk for fragmented coronoid process in Labrador Retrievers. Veterinary Record 2000, 147:149-152.
62. Van Ryssen B., van Bree H. Arthroscopic findings in 100 dogs with elbow lameness. Veterinary Record 1997, 140:360-362.
63. Voorhout G., Hazewinkel H.A. Radiographic evaluation of the canine elbow joint with special reference to the medial humeral condyle and the medial coronoid process. Veterinary Radiology 1987, 28:158-165.
64. Wind A.P., Packard M.E. Elbow incongruity and developmental elbow diseases in the dog: Part II. Journal of the American Animal Hospital Association 1986, 22:725-730.
65. Wolschrijn C.F., Weijs W.A. Development of the trabecular structure within the ulnar medial coronoid process of young dogs. The Anatomical Record-Part A Discoveries in Molecular, Cellular, and Evolutionary Biology 2004, 278:514-519.
66. Wosar M.A., Lewis D.D., Neuwirth L., Parker R.B., Spencer C.P., Kubilis P.S., Stubbs W.P., Murphy S.T., Shiroma J.T., Stallings J.T., Bertrand S.G. Radiographic evaluation of elbow joints before and after surgery in dogs with possible fragmented medial coronoid process. Journal of the American Veterinary Medical Association 1999, 214:52-58.
67. Xu X., Weinstein M., Li C., Chu-Xia Deng C. Fibroblast growth factor receptors (FGFRs) and their roles in limb development. Cell and Tissue Research 1999, 296:33-43.