How does influenza virus a escape from amantadine?

Journal of Physical Chemistry B

Volumn 114, Issue 25, 2010, Pages 8487-8493

  Qin, Guangrong ^a   Yu, Kunqian ^a   Shi, Ting ^a   Luo, Cheng ^a   Li, Guohui ^b   Zhu, Weiliang ^a,c   Jiang, Hualiang ^a,c  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b DALIAN INSTITUTE OF CHEMICAL PHYSICS   (China)

^c EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; BINDING ENERGY; BIOCHEMISTRY; MOLECULAR DYNAMICS; PROTEINS; VIRUSES; WIRE;

AMANTADINE; BINDING MODES; CHANNEL BLOCKING; CHANNEL FUNCTIONS; DRUG BINDING; DRUG RESISTANCE; INFLUENZA A VIRUS; INFLUENZA VIRUS; M2 CHANNEL; MD SIMULATION; MOLECULAR DYNAMICS SIMULATIONS; QM/MM CALCULATIONS; TRANS-MEMBRANE DOMAINS; WILD-TYPE PROTEINS;

BINDING SITES;

AMANTADINE; ANTIVIRUS AGENT; M2 PROTEIN, INFLUENZA A VIRUS; MATRIX PROTEIN;

AMINO ACID SUBSTITUTION; BINDING SITE; CHEMICAL PHENOMENA; CHEMISTRY; GENETICS; INFLUENZA VIRUS A; METABOLISM; MOLECULAR DYNAMICS; MUTATION; PROTEIN TERTIARY STRUCTURE; QUANTUM THEORY;

AMANTADINE; AMINO ACID SUBSTITUTION; ANTIVIRAL AGENTS; BINDING SITES; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; INFLUENZA A VIRUS; MOLECULAR DYNAMICS SIMULATION; MUTATION; PROTEIN STRUCTURE, TERTIARY; QUANTUM THEORY; VIRAL MATRIX PROTEINS;

EID: 77954025043     PISSN: 15206106     EISSN: 15205207     Source Type: Journal    
DOI: 10.1021/jp911588y     Document Type: Article

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