메뉴 건너뛰기




Volumn 139, Issue 1, 2010, Pages

Inhibitor of κB Kinase Beta Regulates Gastric Carcinogenesis via Interleukin-1α Expression

Author keywords

Gastric Cancer; IKK ; Inflammation; NF B

Indexed keywords

DNA FRAGMENT; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; METHYLNITROSOUREA; PROTEIN BCL 2; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR ALPHA; I KAPPA B KINASE; INTERLEUKIN 1 RECEPTOR;

EID: 77953908026     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2010.03.047     Document Type: Article
Times cited : (49)

References (35)
  • 1
    • 43649109029 scopus 로고    scopus 로고
    • Inflammation and cancer: Role of nuclear factor-kappaB activation
    • Maeda S., and Omata M. Inflammation and cancer: Role of nuclear factor-kappaB activation. Cancer Sci 99 (2008) 836-842
    • (2008) Cancer Sci , vol.99 , pp. 836-842
    • Maeda, S.1    Omata, M.2
  • 2
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • Coussens L.M., and Werb Z. Inflammation and cancer. Nature 420 (2002) 860-867
    • (2002) Nature , vol.420 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 3
    • 0036546501 scopus 로고    scopus 로고
    • NF-kappaB in cancer: from innocent bystander to major culprit
    • Karin M., Cao Y., Greten F.R., et al. NF-kappaB in cancer: from innocent bystander to major culprit. Nat Rev Cancer 2 (2002) 301-310
    • (2002) Nat Rev Cancer , vol.2 , pp. 301-310
    • Karin, M.1    Cao, Y.2    Greten, F.R.3
  • 4
    • 0036234459 scopus 로고    scopus 로고
    • Missing pieces in the NF-kappaB puzzle
    • Ghosh S., and Karin M. Missing pieces in the NF-kappaB puzzle. Cell 109 Suppl (2002) S81-S96
    • (2002) Cell , vol.109 , Issue.SUPPL
    • Ghosh, S.1    Karin, M.2
  • 5
    • 0033532386 scopus 로고    scopus 로고
    • The IKKb subunit of IkB kinase (IKK) is essential for NF-kB activation and prevention of apoptosis
    • Li Z.-W., Chu W., Hu Y., et al. The IKKb subunit of IkB kinase (IKK) is essential for NF-kB activation and prevention of apoptosis. J Exp Med 189 (1999) 1839-1845
    • (1999) J Exp Med , vol.189 , pp. 1839-1845
    • Li, Z.-W.1    Chu, W.2    Hu, Y.3
  • 6
    • 4043088499 scopus 로고    scopus 로고
    • IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
    • Greten F.R., Eckmann L., Greten T.F., et al. IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell 118 (2004) 285-296
    • (2004) Cell , vol.118 , pp. 285-296
    • Greten, F.R.1    Eckmann, L.2    Greten, T.F.3
  • 7
    • 4644324186 scopus 로고    scopus 로고
    • NF-kappaB functions as a tumour promoter in inflammation-associated cancer
    • Pikarsky E., Porat R.M., Stein I., et al. NF-kappaB functions as a tumour promoter in inflammation-associated cancer. Nature 431 (2004) 461-466
    • (2004) Nature , vol.431 , pp. 461-466
    • Pikarsky, E.1    Porat, R.M.2    Stein, I.3
  • 8
    • 21244472975 scopus 로고    scopus 로고
    • IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis
    • Maeda S., Kamata H., Luo J.L., et al. IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis. Cell 121 (2005) 977-990
    • (2005) Cell , vol.121 , pp. 977-990
    • Maeda, S.1    Kamata, H.2    Luo, J.L.3
  • 9
    • 0037421484 scopus 로고    scopus 로고
    • NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia
    • Dajee M., Lazarov M., Zhang J.Y., et al. NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia. Nature 421 (2003) 639-643
    • (2003) Nature , vol.421 , pp. 639-643
    • Dajee, M.1    Lazarov, M.2    Zhang, J.Y.3
  • 10
    • 34250722637 scopus 로고    scopus 로고
    • Diet and the risk of gastric cancer: review of epidemiological evidence
    • Tsugane S., and Sasazuki S. Diet and the risk of gastric cancer: review of epidemiological evidence. Gastric Cancer 10 (2007) 75-83
    • (2007) Gastric Cancer , vol.10 , pp. 75-83
    • Tsugane, S.1    Sasazuki, S.2
  • 11
    • 33745596410 scopus 로고    scopus 로고
    • Endogenous versus exogenous exposure to N-nitroso compounds and gastric cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST) study
    • Jakszyn P., Bingham S., Pera G., et al. Endogenous versus exogenous exposure to N-nitroso compounds and gastric cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST) study. Carcinogenesis 27 (2006) 1497-1501
    • (2006) Carcinogenesis , vol.27 , pp. 1497-1501
    • Jakszyn, P.1    Bingham, S.2    Pera, G.3
  • 12
    • 0028230879 scopus 로고
    • Helicobacter pylori infection and gastric lymphoma
    • Parsonnet J., Hansen S., Rodriguez L., et al. Helicobacter pylori infection and gastric lymphoma. N Engl J Med 330 (1994) 1267-1271
    • (1994) N Engl J Med , vol.330 , pp. 1267-1271
    • Parsonnet, J.1    Hansen, S.2    Rodriguez, L.3
  • 13
    • 0035856021 scopus 로고    scopus 로고
    • Helicobacter pylori infection and the development of gastric cancer
    • Uemura N., Okamoto S., Yamamoto S., et al. Helicobacter pylori infection and the development of gastric cancer. N Engl J Med 345 (2001) 784-789
    • (2001) N Engl J Med , vol.345 , pp. 784-789
    • Uemura, N.1    Okamoto, S.2    Yamamoto, S.3
  • 14
    • 0034235373 scopus 로고    scopus 로고
    • H. pylori activates NF-kappaB through a signaling pathway involving IkappaB kinases, NF-kappaB-inducing kinase, TRAF2, and TRAF6 in gastric cancer cells
    • Maeda S., Yoshida H., Ogura K., et al. H. pylori activates NF-kappaB through a signaling pathway involving IkappaB kinases, NF-kappaB-inducing kinase, TRAF2, and TRAF6 in gastric cancer cells. Gastroenterology 119 (2000) 97-108
    • (2000) Gastroenterology , vol.119 , pp. 97-108
    • Maeda, S.1    Yoshida, H.2    Ogura, K.3
  • 15
    • 0030772159 scopus 로고    scopus 로고
    • Helicobacter pylori infection activates NF-kappa B in gastric epithelial cells
    • Keates S., Hitti Y.S., Upton M., et al. Helicobacter pylori infection activates NF-kappa B in gastric epithelial cells. Gastroenterology 113 (1997) 1099-1109
    • (1997) Gastroenterology , vol.113 , pp. 1099-1109
    • Keates, S.1    Hitti, Y.S.2    Upton, M.3
  • 16
    • 0242416989 scopus 로고    scopus 로고
    • IKK beta is required for peripheral B cell survival and proliferation
    • Li Z.W., Omori S.A., Labuda T., et al. IKK beta is required for peripheral B cell survival and proliferation. J Immunol 170 (2003) 4630-4637
    • (2003) J Immunol , vol.170 , pp. 4630-4637
    • Li, Z.W.1    Omori, S.A.2    Labuda, T.3
  • 17
    • 12944336527 scopus 로고    scopus 로고
    • Foxa2 is required for the differentiation of pancreatic alpha-cells
    • Lee C.S., Sund N.J., Behr R., et al. Foxa2 is required for the differentiation of pancreatic alpha-cells. Dev Biol 278 (2005) 484-495
    • (2005) Dev Biol , vol.278 , pp. 484-495
    • Lee, C.S.1    Sund, N.J.2    Behr, R.3
  • 18
    • 0031959559 scopus 로고    scopus 로고
    • N-methyl-N-nitrosourea concentration-dependent, rather than total intake-dependent, induction of adenocarcinomas in the glandular stomach of BALB/c mice
    • Yamachika T., Nakanishi H., Inada K., et al. N-methyl-N-nitrosourea concentration-dependent, rather than total intake-dependent, induction of adenocarcinomas in the glandular stomach of BALB/c mice. Jpn J Cancer Res 89 (1998) 385-391
    • (1998) Jpn J Cancer Res , vol.89 , pp. 385-391
    • Yamachika, T.1    Nakanishi, H.2    Inada, K.3
  • 19
    • 33749249590 scopus 로고    scopus 로고
    • NF-kappaB activation by double-strand breaks
    • Habraken Y., and Piette J. NF-kappaB activation by double-strand breaks. Biochem Pharmacol 72 (2006) 1132-1141
    • (2006) Biochem Pharmacol , vol.72 , pp. 1132-1141
    • Habraken, Y.1    Piette, J.2
  • 20
    • 48549093239 scopus 로고    scopus 로고
    • c-Jun NH2-terminal kinase 1 is a critical regulator for the development of gastric cancer in mice
    • Shibata W., Maeda S., Hikiba Y., et al. c-Jun NH2-terminal kinase 1 is a critical regulator for the development of gastric cancer in mice. Cancer Res 68 (2008) 5031-5039
    • (2008) Cancer Res , vol.68 , pp. 5031-5039
    • Shibata, W.1    Maeda, S.2    Hikiba, Y.3
  • 21
    • 0035889252 scopus 로고    scopus 로고
    • Induction of gadd45beta by NF-kappaB downregulates pro-apoptotic JNK signalling
    • De Smaele E., Zazzeroni F., Papa S., et al. Induction of gadd45beta by NF-kappaB downregulates pro-apoptotic JNK signalling. Nature 414 (2001) 308-313
    • (2001) Nature , vol.414 , pp. 308-313
    • De Smaele, E.1    Zazzeroni, F.2    Papa, S.3
  • 22
    • 14844327760 scopus 로고    scopus 로고
    • Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases
    • Kamata H., Honda S., Maeda S., et al. Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases. Cell 120 (2005) 649-661
    • (2005) Cell , vol.120 , pp. 649-661
    • Kamata, H.1    Honda, S.2    Maeda, S.3
  • 23
    • 0027056713 scopus 로고
    • Potent inhibition of gastric acid secretion and ulcer formation by centrally and peripherally administered interleukin-1
    • Tache Y., and Saperas E. Potent inhibition of gastric acid secretion and ulcer formation by centrally and peripherally administered interleukin-1. Ann N Y Acad Sci 664 (1992) 353-368
    • (1992) Ann N Y Acad Sci , vol.664 , pp. 353-368
    • Tache, Y.1    Saperas, E.2
  • 24
    • 0027313598 scopus 로고
    • Interleukin 1 alpha acts as an autocrine growth stimulator for human gastric carcinoma cells
    • Ito R., Kitadai Y., Kyo E., et al. Interleukin 1 alpha acts as an autocrine growth stimulator for human gastric carcinoma cells. Cancer Res 53 (1993) 4102-4106
    • (1993) Cancer Res , vol.53 , pp. 4102-4106
    • Ito, R.1    Kitadai, Y.2    Kyo, E.3
  • 25
    • 0034704880 scopus 로고    scopus 로고
    • Interleukin-1 polymorphisms associated with increased risk of gastric cancer
    • El-Omar E.M., Carrington M., Chow W.H., et al. Interleukin-1 polymorphisms associated with increased risk of gastric cancer. Nature 404 (2000) 398-402
    • (2000) Nature , vol.404 , pp. 398-402
    • El-Omar, E.M.1    Carrington, M.2    Chow, W.H.3
  • 26
    • 0037079615 scopus 로고    scopus 로고
    • Interleukin-1alpha up-regulation in vivo by a potent carcinogen 7,12-dimethylbenz(a)anthracene (DMBA) and control of DMBA-induced inflammatory responses
    • Li X., Eckard J., Shah R., et al. Interleukin-1alpha up-regulation in vivo by a potent carcinogen 7,12-dimethylbenz(a)anthracene (DMBA) and control of DMBA-induced inflammatory responses. Cancer Res 62 (2002) 417-423
    • (2002) Cancer Res , vol.62 , pp. 417-423
    • Li, X.1    Eckard, J.2    Shah, R.3
  • 27
    • 54549089856 scopus 로고    scopus 로고
    • Overexpression of interleukin-1beta induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice
    • Tu S., Bhagat G., Cui G., et al. Overexpression of interleukin-1beta induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice. Cancer Cell 14 (2008) 408-419
    • (2008) Cancer Cell , vol.14 , pp. 408-419
    • Tu, S.1    Bhagat, G.2    Cui, G.3
  • 28
    • 48649109203 scopus 로고    scopus 로고
    • Hepatocyte necrosis induced by oxidative stress and IL-1 alpha release mediate carcinogen-induced compensatory proliferation and liver tumorigenesis
    • Sakurai T., He G., Matsuzawa A., et al. Hepatocyte necrosis induced by oxidative stress and IL-1 alpha release mediate carcinogen-induced compensatory proliferation and liver tumorigenesis. Cancer Cell 14 (2008) 156-165
    • (2008) Cancer Cell , vol.14 , pp. 156-165
    • Sakurai, T.1    He, G.2    Matsuzawa, A.3
  • 29
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D., and Weinberg R.A. The hallmarks of cancer. Cell 100 (2000) 57-70
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 30
    • 0034304668 scopus 로고    scopus 로고
    • The Toll/interleukin-1 receptor domain: a molecular switch for inflammation and host defence
    • O'Neill L. The Toll/interleukin-1 receptor domain: a molecular switch for inflammation and host defence. Biochem Soc Trans 28 (2000) 557-563
    • (2000) Biochem Soc Trans , vol.28 , pp. 557-563
    • O'Neill, L.1
  • 31
    • 0034606275 scopus 로고    scopus 로고
    • Virulence factors of Helicobacter pylori responsible for gastric diseases in Mongolian gerbil
    • Ogura K., Maeda S., Nakao M., et al. Virulence factors of Helicobacter pylori responsible for gastric diseases in Mongolian gerbil. J Exp Med 192 (2000) 1601-1610
    • (2000) J Exp Med , vol.192 , pp. 1601-1610
    • Ogura, K.1    Maeda, S.2    Nakao, M.3
  • 32
    • 39149108151 scopus 로고    scopus 로고
    • Activation of IkappaB kinase and NF-kappaB is essential for Helicobacter pylori-induced chronic gastritis in Mongolian gerbils
    • Yanai A., Maeda S., Shibata W., et al. Activation of IkappaB kinase and NF-kappaB is essential for Helicobacter pylori-induced chronic gastritis in Mongolian gerbils. Infect Immun 76 (2008) 781-787
    • (2008) Infect Immun , vol.76 , pp. 781-787
    • Yanai, A.1    Maeda, S.2    Shibata, W.3
  • 33
    • 12644302230 scopus 로고    scopus 로고
    • Helicobacter pylori induces proinflammatory cytokines and major histocompatibility complex class II antigen in mouse gastric epithelial cells
    • Maekawa T., Kinoshita Y., Matsushima Y., et al. Helicobacter pylori induces proinflammatory cytokines and major histocompatibility complex class II antigen in mouse gastric epithelial cells. J Lab Clin Med 130 (1997) 442-449
    • (1997) J Lab Clin Med , vol.130 , pp. 442-449
    • Maekawa, T.1    Kinoshita, Y.2    Matsushima, Y.3
  • 34
    • 39149133212 scopus 로고    scopus 로고
    • NF-kappaB activation during acute Helicobacter pylori infection in mice
    • Ferrero R.L., Ave P., Ndiaye D., et al. NF-kappaB activation during acute Helicobacter pylori infection in mice. Infect Immun 76 (2008) 551-561
    • (2008) Infect Immun , vol.76 , pp. 551-561
    • Ferrero, R.L.1    Ave, P.2    Ndiaye, D.3
  • 35
    • 77449146686 scopus 로고    scopus 로고
    • Conditional deletion of IkappaB-kinase-beta accelerates Helicobacter-dependent gastric apoptosis, proliferation, and preneoplasia
    • Shibata W., Takaishi S., Muthupalani S., et al. Conditional deletion of IkappaB-kinase-beta accelerates Helicobacter-dependent gastric apoptosis, proliferation, and preneoplasia. Gastroenterology 138 (2010) 1022-1034
    • (2010) Gastroenterology , vol.138 , pp. 1022-1034
    • Shibata, W.1    Takaishi, S.2    Muthupalani, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.