Endogenous versus exogenous exposure to N-nitroso compounds and gastric cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST) study

Carcinogenesis

Volumn 27, Issue 7, 2006, Pages 1497-1501

  Jakszyn, Paula ^ad   Bingham, Sheila ^a   Pera, Guillem ^ad   Agudo, Antonio ^ad   Luben, Robert ^b   Welch, Ailsa ^b   Boeing, Heiner ^c   del Giudice, Giuseppe ^d   Palli, Domenico ^e   Saieva, Calogero ^e   Krogh, Vittorio ^f   Sacerdote, Carlotta ^g   Tumino, Rosario ^h   Panico, Salvatore ⁱ   Berglund, Göran ^j   Simán, Henrik ^j   Hallmans, Göran ^k   Sanchez, María José ^l   Larrañaga, Nerea ^m   Barricarte, Aurelio ⁿ   Chirlaque, María Dolores ^o   Quirós, José R ^p   Key, Timothy J ^q   Allen, Naomi ^q   Lund, Eiliv ^r   Carneiro, Fátima ^s   Linseisen, Jakob ^t   Nagel, Gabriele ^t   Overvad, Kim ^u   Tjonneland, Anne ^v   Olsen, Anja ^v   Bueno de Mesquita, H Bas ^w   Ocké, Marga O ^w   Peeters, Petra H M ^x   Numans, Mattijs E ^x   Clavel Chapelon, Françoise ^y   Trichopoulou, Antonia ^z   Fenger, Claus ^aa   Stenling, Roger ^k   Ferrari, Pietro ^ab   Jenab, Mazda ^ab   Norat, Teresa ^ab   Riboli, Elio ^ab,ac   Gonzalez, Carlos A ^ad   more..

^a WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

^d CHIRON VACCINES   (Italy)

^e CANCER RESEARCH AND PREVENTION INSTITUTE ISPO   (Italy)

^f NATIONAL CANCER INSTITUTE   (Italy)

^g UNIVERSITY OF TURIN   (Italy)

^h CIVILE M P AREZZO HOSPITAL   (Italy)

ⁱ UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^j LUND UNIVERSITY HOSPITAL   (Sweden)

^k UMEÅ UNIVERSITY   (Sweden)

^l ANDALUSIAN SCHOOL OF PUBLIC HEALTH   (Spain)

^m Department of Public Health of Guipuzkoa ^*  (Spain)

ⁿ INSTITUTO DE SALUD PÚBLICA DE NAVARRA   (Spain)

^o DEPARTMENT OF EPIDEMIOLOGY   (Spain)

^p Public Health and Health Planning Directorate   (Spain)

^q UNIVERSITY OF OXFORD   (United Kingdom)

^r UNIVERSITY OF TROMSØ   (Norway)

^s University of Porto   (Portugal)

^t GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^u AALBORG UNIVERSITY HOSPITAL   (Denmark)

^v INSTITUTE OF CANCER EPIDEMIOLOGY   (Denmark)

^w NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^x UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^y INSTITUT GUSTAVE ROUSSY   (France)

^z UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^aa UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^ab INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

^ac IMPERIAL COLLEGE LONDON   (United Kingdom)

^ad CATALAN INSTITUTE OF ONCOLOGY   (Spain)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ASCORBIC ACID; BACTERIUM ANTIBODY; DIMETHYLNITROSAMINE; IRON; NITROSO DERIVATIVE;

ADULT; ARTICLE; CANCER RISK; CARDIA; CASE CONTROL STUDY; CONFIDENCE INTERVAL; CONTROLLED STUDY; CORRELATION ANALYSIS; DIETARY INTAKE; DISEASE ASSOCIATION; EXPOSURE; FECES LEVEL; FEMALE; FOLLOW UP; FOOD PROCESSING; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; MAJOR CLINICAL STUDY; MALE; MEAT; MEDICAL RESEARCH; PRIORITY JOURNAL; PUBLISHING; RISK ASSESSMENT; STATISTICAL SIGNIFICANCE; STOMACH CANCER; TISSUE LEVEL; VITAMIN BLOOD LEVEL;

ADENOCARCINOMA; ANIMALS; ASCORBIC ACID; CASE-CONTROL STUDIES; CATTLE; DIET; DIMETHYLNITROSAMINE; EUROPE; FEMALE; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; IRON; MALE; MEAT; MIDDLE AGED; NITROSAMINES; PROSPECTIVE STUDIES; RISK FACTORS; STOMACH NEOPLASMS;

EID: 33745596410     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgl019     Document Type: Article

References (23)

1. Tricker,A.R. (1997) N-nitroso compounds and man: Sources of exposure, endogenous formation and occurrence in body fluids. Eur. J. Cancer Prev., 6, 226-268.
2. World Cancer Research Fund. (1997) Food, Nutrition and the Prevention of Cancer: A Global Perspective. American Institute for Cancer Research, Washington, DC.
3. Gonzalez,C.A., Jakszyn,P., Pera,G. et al. (2006) Meat intake and risk of stomach and esophageal adenocarcinoma within the European Prospective Investigation into Cancer and Nutrition (EPIC). J. Natl. Cancer Inst., 98, 345-354.
4. Bingham,S.A., Pignatelli,B., Pollock,J.R., Ellul,A., Malaveille,C., Gross,G., Runswick,S., Cummings,J.H. and O'Neill,I.K. (1996) Does increased endogenous formation of N-nitroso compounds in the human colon explain the association between red meat and colon cancer? Carcinogenesis, 17, 515-523.
5. Cross,A.J., Pollock,J.R. and Bingham,S.A. (2003) Haem, not protein or inorganic iron, is responsible for endogenous intestinal N-nitrosation arising from red meat. Cancer Res., 63, 2358-2360.
6. Bonnett,R., Holleyhead,R., Johnson,B.L. and Randall,E.W. (1975) Reaction of acidified nitrite solutions with peptide derivatives: Evidence for nitrosamine and thionitrite formation from 15N NMR studies. J. Chem. Soc. [Perkin 1],, 22, 2261-2271.
7. Wade,R.S. and Castro,C.E. (1990) Redox reactivity of iron(III) porphyrins and heme proteins with nitric oxide. Nitrosyl transfer to carbon, oxygen, nitrogen, and sulfur. Chem. Res. Toxicol., 3, 289-291.
8. Hirst,J. and Goodin,D.B. (2000) Unusual oxidative chemistry of N-(omega)-hydroxyarginine and N-hydroxyguanidine catalyzed at an engineered cavity in a heme peroxidase. J. Biol. Chem., 275, 8582-8591.
9. Lunn,J., Pollock,J. and Bingham,S. (2004) The effect of increased red and processed meat on endogenous formation of N-nitroso compounds and DNA strand breaks in ileostomists. Cancer Epidemiol. Biomarkers Prev., 13 ((Suppl. 11) Abstract), A 95-1852.
10. Riboli,E., Hunt,K.J., Slimani,N. et al. (2002) European Prospective Investigation into Cancer and Nutrition (EPIC): Study populations and data collection. Public Health Nutr., 5, 1113-1124.
11. World Health Organization. (1992) International Statistical Classification of Diseases and Related Health Problems.10th version, WHO, Geneva.
12. Jakszyn,P., Agudo,A., Ibanez,R., Garcia-Closas,R., Pera,G., Amiano,P. and Gonzalez,C.A. (2004) Development of a food database of nitrosamines, heterocyclic amines, and polycyclic aromatic hydrocarbons. J. Nutr, 134, 2011-2014.
13. Hughes,R., Cross,A.J., Pollock,J.R. and Bingham,S. Dose-dependent effect of dietary meat on endogenous colonic N-nitrosation. [Erratum in: Carcinogenesis 2001 22, 685.] Carcinogenesis, 22, 199-202.
14. Silvester,K.R., Bingham,S.A., Pollock,J.R., Cummings,J.H. and O'Neill,I.K. (1997) Effect of meat and resistant starch on fecal excretion of apparent N-nitroso compounds and ammonia from the human large bowel. Nutr. Cancer, 29, 13-23.
15. Food Standards Agency. (2002) McCance and Widdowson's The Composition of Foods. Sixth summary edition. Royal Society of Chemistry, Cambridge.
16. Knekt,P., Jarvinen,R., Dich,J. and Hakulinen,T. (1999) Risk of colorectal and other gastro-intestinal cancers after exposure to nitrate, nitrite and N-nitroso compounds: A follow-up study. Int. J. Cancer, 80, 852-856.
17. Ministry of Agriculture, Fisheries and Food. (1992) Nitrate, Nitrite and N-Nitrosocompounds in Foods. Second Report. Food surveillance Paper No. 23. HMSO, London.
18. Carpenter,C.E. and Clark,E. (1995) Evaluation of methods used in meat iron analysis and iron content of raw and cooked meats. J. Agric. Food Chem., 43, 1824-1827.
19. International Agency for Research on Cancer. (2002) IARC Monogaphs. Tobacco smoking and tobacco smoke. IARC, Lyon.
20. Gonzalez,C.A., Pera,G., Agudo,A. et al. (2003) Smoking and the risk of gastric cancer in the European Prospective Investigation Into Cancer and Nutrition (EPIC). Int. J. Cancer, 107, 629-634.
21. Helicobacter and Cancer Collaborative Group. (2001) Gastric cancer and Helicobacter pylori: A combined analysis of 12 case control studies nested within prospective cohorts. Gut, 49, 347-353.
22. Pignatelli,B., Bancel,B., Esteve,J., Malaveille,C., Calmels,S., Correa,P., Patricot,L.M., Laval,M., Lyandrat,N. and Ohshima,H. (1998) Inducible nitric oxide synthase, anti-oxidant enzymes and Helicobacter pylori infection in gastritis and gastric precancerous lesions in humans. Eur. J. Cancer Prev., 7, 439-447.
23. Zhang,Z.W. and Farthing,M.J. (2005) The roles of vitamin C in Helicobacter pylori associated gastric carcinogenesis. Chin. J. Dig. Dis., 6, 53-58.