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Volumn 47, Issue 3, 2010, Pages 289-298

Toxicities of the Thrombopoietic Growth Factors

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; AZACITIDINE; ELTROMBOPAG; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN; LENALIDOMIDE; NEUTRALIZING ANTIBODY; PLACEBO; RECOMBINANT MEGAKARYOCYTE GROWTH AND DEVELOPMENT FACTOR; RECOMBINANT THROMBOPOIETIN; ROMIPLOSTIM; THROMBOPOIETIN;

EID: 77953889162     PISSN: 00371963     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.seminhematol.2010.03.002     Document Type: Article
Times cited : (45)

References (53)
  • 1
    • 33750035507 scopus 로고    scopus 로고
    • AMG 531, a thrombopoiesis-stimulating protein, for chronic ITP
    • Bussel J.B., Kuter D.J., George J.N., et al. AMG 531, a thrombopoiesis-stimulating protein, for chronic ITP. N Engl J Med 2006, 355:1672-1681.
    • (2006) N Engl J Med , vol.355 , pp. 1672-1681
    • Bussel, J.B.1    Kuter, D.J.2    George, J.N.3
  • 2
    • 38649120593 scopus 로고    scopus 로고
    • Efficacy of romiplostim in patients with chronic immune thrombocytopenic purpura: a double-blind randomised controlled trial
    • Kuter D.J., Bussel J.B., Lyons R.M., et al. Efficacy of romiplostim in patients with chronic immune thrombocytopenic purpura: a double-blind randomised controlled trial. Lancet 2008, 371:395-403.
    • (2008) Lancet , vol.371 , pp. 395-403
    • Kuter, D.J.1    Bussel, J.B.2    Lyons, R.M.3
  • 3
    • 77953888347 scopus 로고    scopus 로고
    • Comparison of splenectomy and treatment failure incidence in nonsplenectomized patients with immune thrombocytopenia (ITP) receiving romiplostim or medical standard of care: 1-year treatment and 6-month safety follow-up [abstract]
    • Kuter D.J., Rummel M.J., Boccia R.V., et al. Comparison of splenectomy and treatment failure incidence in nonsplenectomized patients with immune thrombocytopenia (ITP) receiving romiplostim or medical standard of care: 1-year treatment and 6-month safety follow-up [abstract]. ASH Annual Meeting Abstracts 2009, 114:679.
    • (2009) ASH Annual Meeting Abstracts , vol.114 , pp. 679
    • Kuter, D.J.1    Rummel, M.J.2    Boccia, R.V.3
  • 4
    • 77953903071 scopus 로고    scopus 로고
    • Six month treatment of low dose eltrombopag is efficacious in Japanese patients with refractory chronic immune thrombocytopenic purpura (ITP) [abstract]
    • Tomiyama Y., Miyakawa Y., Okamoto S., et al. Six month treatment of low dose eltrombopag is efficacious in Japanese patients with refractory chronic immune thrombocytopenic purpura (ITP) [abstract]. ASH Annual Meeting Abstracts 2009, 114:1324.
    • (2009) ASH Annual Meeting Abstracts , vol.114 , pp. 1324
    • Tomiyama, Y.1    Miyakawa, Y.2    Okamoto, S.3
  • 5
    • 36549001698 scopus 로고    scopus 로고
    • Eltrombopag for the treatment of chronic idiopathic thrombocytopenic purpura
    • Bussel J.B., Cheng G., Saleh M.N., et al. Eltrombopag for the treatment of chronic idiopathic thrombocytopenic purpura. N Engl J Med 2007, 357:2237-2247.
    • (2007) N Engl J Med , vol.357 , pp. 2237-2247
    • Bussel, J.B.1    Cheng, G.2    Saleh, M.N.3
  • 6
    • 60249099882 scopus 로고    scopus 로고
    • Effect of eltrombopag on platelet counts and bleeding during treatment of chronic idiopathic thrombocytopenic purpura: a randomized, double-blind, placebo-controlled trial
    • Bussel J.B., Provan D., Shamsi T., et al. Effect of eltrombopag on platelet counts and bleeding during treatment of chronic idiopathic thrombocytopenic purpura: a randomized, double-blind, placebo-controlled trial. Lancet 2009, 373:641-648.
    • (2009) Lancet , vol.373 , pp. 641-648
    • Bussel, J.B.1    Provan, D.2    Shamsi, T.3
  • 7
    • 60249095603 scopus 로고    scopus 로고
    • Oral eltrombopag for the long-term treatment of patients with chronic idiopathic thrombocytopenic purpura: results of a phase III double-blind, placebo-controlled study (RAISE) [abstract]
    • Cheng G., Saleh M.N., Bussel J.B., et al. Oral eltrombopag for the long-term treatment of patients with chronic idiopathic thrombocytopenic purpura: results of a phase III double-blind, placebo-controlled study (RAISE) [abstract]. ASH Annual Meeting Abstracts 2008, 112:400.
    • (2008) ASH Annual Meeting Abstracts , vol.112 , pp. 400
    • Cheng, G.1    Saleh, M.N.2    Bussel, J.B.3
  • 8
    • 77953437158 scopus 로고    scopus 로고
    • Long-term efficacy and safety of romiplostim for the treatment of patients with chronic immune thrombocytopenia (ITP): 5-year update from an open-label extension study [abstract]
    • Bussel J.B., Kuter D.J., Newland A., et al. Long-term efficacy and safety of romiplostim for the treatment of patients with chronic immune thrombocytopenia (ITP): 5-year update from an open-label extension study [abstract]. ASH Annual Meeting Abstracts 2009, 114:681.
    • (2009) ASH Annual Meeting Abstracts , vol.114 , pp. 681
    • Bussel, J.B.1    Kuter, D.J.2    Newland, A.3
  • 9
    • 77953437158 scopus 로고    scopus 로고
    • Long-term treatment of chronic immune thrombocytopenic purpura with oral eltrombopag: results from the EXTEND study [abstract]
    • Saleh M.N., Bussel J.B., Cheng G., et al. Long-term treatment of chronic immune thrombocytopenic purpura with oral eltrombopag: results from the EXTEND study [abstract]. ASH Annual Meeting Abstracts 2009, 114:682.
    • (2009) ASH Annual Meeting Abstracts , vol.114 , pp. 682
    • Saleh, M.N.1    Bussel, J.B.2    Cheng, G.3
  • 10
    • 34848876335 scopus 로고    scopus 로고
    • Bone marrow fibrosis: physiology and clinical significance of increased bone marrow stromal fibres
    • Kuter D.J., Bain B., Mufti G., Bagg A., Hasserjian R.P. Bone marrow fibrosis: physiology and clinical significance of increased bone marrow stromal fibres. Br J Haematol 2007, 139:351-362.
    • (2007) Br J Haematol , vol.139 , pp. 351-362
    • Kuter, D.J.1    Bain, B.2    Mufti, G.3    Bagg, A.4    Hasserjian, R.P.5
  • 11
    • 0015090542 scopus 로고
    • Quantitation of bone marrow reticulin-a normal change
    • Bauermeister D.E. Quantitation of bone marrow reticulin-a normal change. Am J Clin Pathol 1971, 56:24-31.
    • (1971) Am J Clin Pathol , vol.56 , pp. 24-31
    • Bauermeister, D.E.1
  • 12
    • 0025605489 scopus 로고
    • Normal reticulin level in iliac bone marrow
    • Beckman E.N., Brown A.W. Normal reticulin level in iliac bone marrow. Arch Pathol Lab Med 1990, 114:1241-1243.
    • (1990) Arch Pathol Lab Med , vol.114 , pp. 1241-1243
    • Beckman, E.N.1    Brown, A.W.2
  • 14
    • 0024419833 scopus 로고
    • Transforming growth factor-beta regulates growth as well as collagen and fibronectin synthesis of human marrow fibroblasts
    • Kimura A., Katoh O., Hyodo H., Kuramoto A. Transforming growth factor-beta regulates growth as well as collagen and fibronectin synthesis of human marrow fibroblasts. Br J Haematol 1989, 72:486-491.
    • (1989) Br J Haematol , vol.72 , pp. 486-491
    • Kimura, A.1    Katoh, O.2    Hyodo, H.3    Kuramoto, A.4
  • 15
    • 0025232370 scopus 로고
    • The production of transforming growth factor-beta in acute megakaryoblastic leukemia and its possible implications in myelofibrosis
    • Terui T., Niitsu Y., Mahara K., et al. The production of transforming growth factor-beta in acute megakaryoblastic leukemia and its possible implications in myelofibrosis. Blood 1990, 75:1540-1548.
    • (1990) Blood , vol.75 , pp. 1540-1548
    • Terui, T.1    Niitsu, Y.2    Mahara, K.3
  • 16
    • 0029897491 scopus 로고    scopus 로고
    • Systemic hematologic effects of PEG-rHuMGDF-induced megakaryocyte hyperplasia in mice
    • Ulich T.R., del Castillo J., Senaldi G., et al. Systemic hematologic effects of PEG-rHuMGDF-induced megakaryocyte hyperplasia in mice. Blood 1996, 87:5006-5015.
    • (1996) Blood , vol.87 , pp. 5006-5015
    • Ulich, T.R.1    del Castillo, J.2    Senaldi, G.3
  • 17
    • 6844250789 scopus 로고    scopus 로고
    • The role of transforming growth factor-beta in PEG-rHuMGDF-induced reversible myelofibrosis in rats
    • Yanagida M., Ide Y., Imai A., et al. The role of transforming growth factor-beta in PEG-rHuMGDF-induced reversible myelofibrosis in rats. Br J Haematol 1997, 99:739-745.
    • (1997) Br J Haematol , vol.99 , pp. 739-745
    • Yanagida, M.1    Ide, Y.2    Imai, A.3
  • 18
    • 70449704426 scopus 로고    scopus 로고
    • Evaluation of bone marrow reticulin formation in chronic immune thrombocytopenia patients treated with romiplostim
    • Kuter D.J., Mufti G., Bain B.J., Hasserjian R., Davis W., Rutstein M. Evaluation of bone marrow reticulin formation in chronic immune thrombocytopenia patients treated with romiplostim. Blood 2009, 114:3748-3756.
    • (2009) Blood , vol.114 , pp. 3748-3756
    • Kuter, D.J.1    Mufti, G.2    Bain, B.J.3    Hasserjian, R.4    Davis, W.5    Rutstein, M.6
  • 19
    • 0028843848 scopus 로고
    • Chronic exposure to retroviral vector encoded MGDF (mpl-ligand) induces lineage-specific growth and differentiation of megakaryocytes in mice
    • Yan X.Q., Lacey D., Fletcher F., et al. Chronic exposure to retroviral vector encoded MGDF (mpl-ligand) induces lineage-specific growth and differentiation of megakaryocytes in mice. Blood 1995, 86:4025-4033.
    • (1995) Blood , vol.86 , pp. 4025-4033
    • Yan, X.Q.1    Lacey, D.2    Fletcher, F.3
  • 20
    • 0036263664 scopus 로고    scopus 로고
    • Thrombopoietin administered during induction chemotherapy to patients with acute myeloid leukemia induces transient morphologic changes that may resemble chronic myeloproliferative disorders
    • Douglas V.K., Tallman M.S., Cripe L.D., Peterson L.C. Thrombopoietin administered during induction chemotherapy to patients with acute myeloid leukemia induces transient morphologic changes that may resemble chronic myeloproliferative disorders. Am J Clin Pathol 2002, 117:844-850.
    • (2002) Am J Clin Pathol , vol.117 , pp. 844-850
    • Douglas, V.K.1    Tallman, M.S.2    Cripe, L.D.3    Peterson, L.C.4
  • 22
    • 77953900802 scopus 로고    scopus 로고
    • Results of bone marrow examinations in patients with chronic immune thrombocytopenic purpura treated with eltrombopag [abstract]
    • Saleh M.N., Bussel J.B., Meyer O., et al. Results of bone marrow examinations in patients with chronic immune thrombocytopenic purpura treated with eltrombopag [abstract]. ASH Annual Meeting Abstracts 2009, 114:1326.
    • (2009) ASH Annual Meeting Abstracts , vol.114 , pp. 1326
    • Saleh, M.N.1    Bussel, J.B.2    Meyer, O.3
  • 23
    • 77950845568 scopus 로고    scopus 로고
    • Safety of the thrombopoiesis stimulating agents for the treatment of immune thrombocytopenia
    • Cuker A., Chiang E.Y., Cines D.B. Safety of the thrombopoiesis stimulating agents for the treatment of immune thrombocytopenia. Curr Drug Saf 2010, 5:171-181.
    • (2010) Curr Drug Saf , vol.5 , pp. 171-181
    • Cuker, A.1    Chiang, E.Y.2    Cines, D.B.3
  • 24
    • 3042637761 scopus 로고    scopus 로고
    • Prospective screening of 205 patients with ITP, including diagnosis, serological markers, and the relationship between platelet counts, endogenous thrombopoietin, and circulating antithrombopoietin antibodies
    • Aledort L.M., Hayward C.P., Chen M.G., Nichol J.L., Bussel J. Prospective screening of 205 patients with ITP, including diagnosis, serological markers, and the relationship between platelet counts, endogenous thrombopoietin, and circulating antithrombopoietin antibodies. Am J Hematol 2004, 76:205-213.
    • (2004) Am J Hematol , vol.76 , pp. 205-213
    • Aledort, L.M.1    Hayward, C.P.2    Chen, M.G.3    Nichol, J.L.4    Bussel, J.5
  • 25
    • 80051590648 scopus 로고    scopus 로고
    • Risk of thromboembolic events among patients with chronic idiopathic thrombocytopenic purpura (ITP) [abstract]
    • s
    • Bennett I., Forssen U., Enger C., Nelson J. Risk of thromboembolic events among patients with chronic idiopathic thrombocytopenic purpura (ITP) [abstract]. EHA Annual Meeting Abstracts 2008, 93(s1):307.
    • (2008) EHA Annual Meeting Abstracts , vol.93 , Issue.1 , pp. 307
    • Bennett, I.1    Forssen, U.2    Enger, C.3    Nelson, J.4
  • 26
    • 20444471583 scopus 로고    scopus 로고
    • Thromboembolic events as an emerging adverse effect during high-dose intravenous immunoglobulin therapy in elderly patients: a case report and discussion of the relevant literature
    • Hefer D., Jaloudi M. Thromboembolic events as an emerging adverse effect during high-dose intravenous immunoglobulin therapy in elderly patients: a case report and discussion of the relevant literature. Ann Hematol 2005, 84:411-415.
    • (2005) Ann Hematol , vol.84 , pp. 411-415
    • Hefer, D.1    Jaloudi, M.2
  • 27
    • 2542551270 scopus 로고    scopus 로고
    • Thromboembolic complications after splenectomy for hematologic diseases
    • Mohren M., Markmann I., Dworschak U., et al. Thromboembolic complications after splenectomy for hematologic diseases. Am J Hematol 2004, 76:143-147.
    • (2004) Am J Hematol , vol.76 , pp. 143-147
    • Mohren, M.1    Markmann, I.2    Dworschak, U.3
  • 28
    • 0030068687 scopus 로고    scopus 로고
    • Regulation of platelet production and function by megakaryocyte growth and development factor in nonhuman primates
    • Harker L.A., Hunt P., Marzec U.M., et al. Regulation of platelet production and function by megakaryocyte growth and development factor in nonhuman primates. Blood 1996, 87:1833-1844.
    • (1996) Blood , vol.87 , pp. 1833-1844
    • Harker, L.A.1    Hunt, P.2    Marzec, U.M.3
  • 29
    • 0029943307 scopus 로고    scopus 로고
    • Dose-response effects of pegylated human megakaryocyte growth and development factor on platelet production and function in nonhuman primates
    • Harker L.A., Marzec U.M., Hunt P., et al. Dose-response effects of pegylated human megakaryocyte growth and development factor on platelet production and function in nonhuman primates. Blood 1996, 88:511-521.
    • (1996) Blood , vol.88 , pp. 511-521
    • Harker, L.A.1    Marzec, U.M.2    Hunt, P.3
  • 30
    • 0029923645 scopus 로고    scopus 로고
    • Relative reactivity of platelets from thrombopoietin- and interleukin-6-treated dogs
    • Peng J., Friese P., Wolf R.F., et al. Relative reactivity of platelets from thrombopoietin- and interleukin-6-treated dogs. Blood 1996, 87:4158-4163.
    • (1996) Blood , vol.87 , pp. 4158-4163
    • Peng, J.1    Friese, P.2    Wolf, R.F.3
  • 31
    • 68549092703 scopus 로고    scopus 로고
    • Comparative analyses of the small molecule thrombopoietin receptor agonist eltrombopag and thrombopoietin on in vitro platelet function
    • Erhardt J.A., Erickson-Miller C.L., Aivado M., Abboud M., Pillarisetti K., Toomey J.R. Comparative analyses of the small molecule thrombopoietin receptor agonist eltrombopag and thrombopoietin on in vitro platelet function. Exp Hematol 2009, 37:1030-1037.
    • (2009) Exp Hematol , vol.37 , pp. 1030-1037
    • Erhardt, J.A.1    Erickson-Miller, C.L.2    Aivado, M.3    Abboud, M.4    Pillarisetti, K.5    Toomey, J.R.6
  • 32
    • 0030966361 scopus 로고    scopus 로고
    • Stimulation of megakaryocyte and platelet production by a single dose of recombinant human thrombopoietin in patients with cancer
    • Vadhan-Raj S., Murray L.J., Bueso-Ramos C., et al. Stimulation of megakaryocyte and platelet production by a single dose of recombinant human thrombopoietin in patients with cancer. Ann Intern Med 1997, 126:673-681.
    • (1997) Ann Intern Med , vol.126 , pp. 673-681
    • Vadhan-Raj, S.1    Murray, L.J.2    Bueso-Ramos, C.3
  • 33
    • 0031049879 scopus 로고    scopus 로고
    • Effects of polyethylene glycol-conjugated recombinant human megakaryocyte growth and development factor on platelet counts after chemotherapy for lung cancer
    • Fanucchi M., Glaspy J., Crawford J., et al. Effects of polyethylene glycol-conjugated recombinant human megakaryocyte growth and development factor on platelet counts after chemotherapy for lung cancer. N Engl J Med 1997, 336:404-409.
    • (1997) N Engl J Med , vol.336 , pp. 404-409
    • Fanucchi, M.1    Glaspy, J.2    Crawford, J.3
  • 34
    • 0033861984 scopus 로고    scopus 로고
    • Enhancement of platelet recovery after myelosuppressive chemotherapy by recombinant human megakaryocyte growth and development factor in patients with advanced cancer
    • Basser R.L., Underhill C., Davis I., et al. Enhancement of platelet recovery after myelosuppressive chemotherapy by recombinant human megakaryocyte growth and development factor in patients with advanced cancer. J Clin Oncol 2000, 18:2852-2861.
    • (2000) J Clin Oncol , vol.18 , pp. 2852-2861
    • Basser, R.L.1    Underhill, C.2    Davis, I.3
  • 35
    • 72149125815 scopus 로고    scopus 로고
    • Long-term safety profile of romiplostim in patients with chronic immune thrombocytopenia (ITP) [abstract]
    • Liebman H., Henry D., Lefrere F., et al. Long-term safety profile of romiplostim in patients with chronic immune thrombocytopenia (ITP) [abstract]. ASH Annual Meeting Abstracts 2008, 112:3415.
    • (2008) ASH Annual Meeting Abstracts , vol.112 , pp. 3415
    • Liebman, H.1    Henry, D.2    Lefrere, F.3
  • 36
    • 79251631806 scopus 로고    scopus 로고
    • Thromboembolic events observed in eltrombopag clinical trials in chronic immune thrombocytopenic purpura [abstract]
    • Bussel J.B., Cheng G., Saleh M.N., Vasey S., Aivado M., Brainsky A. Thromboembolic events observed in eltrombopag clinical trials in chronic immune thrombocytopenic purpura [abstract]. ASH Annual Meeting Abstracts 2009, 114:2423.
    • (2009) ASH Annual Meeting Abstracts , vol.114 , pp. 2423
    • Bussel, J.B.1    Cheng, G.2    Saleh, M.N.3    Vasey, S.4    Aivado, M.5    Brainsky, A.6
  • 37
    • 77953896621 scopus 로고    scopus 로고
    • Platelet counts following eltrombopag discontinuation in patients with chronic immune thrombocytopenic purpura [abstract]
    • Cheng G., Tarantino M., Gernsheimer T., Meyer O., Brainsky A., Stone N.L. Platelet counts following eltrombopag discontinuation in patients with chronic immune thrombocytopenic purpura [abstract]. ASH Annual Meeting Abstracts 2009, 114:3517.
    • (2009) ASH Annual Meeting Abstracts , vol.114 , pp. 3517
    • Cheng, G.1    Tarantino, M.2    Gernsheimer, T.3    Meyer, O.4    Brainsky, A.5    Stone, N.L.6
  • 38
    • 33750517284 scopus 로고    scopus 로고
    • Autoimmune diseases, asthma and risk of haematological malignancies: a nationwide case-control study in Sweden
    • Söderberg K.C., Jonsson F., Winqvist O., Hagmar L., Feychting M. Autoimmune diseases, asthma and risk of haematological malignancies: a nationwide case-control study in Sweden. Eur J Cancer 2006, 42:3028-3033.
    • (2006) Eur J Cancer , vol.42 , pp. 3028-3033
    • Söderberg, K.C.1    Jonsson, F.2    Winqvist, O.3    Hagmar, L.4    Feychting, M.5
  • 39
    • 33749002249 scopus 로고    scopus 로고
    • Autoimmunity and susceptibility to Hodgkin lymphoma: a population-based case-control study in Scandinavia
    • Landgren O., Engels E.A., Pfeiffer R.M., et al. Autoimmunity and susceptibility to Hodgkin lymphoma: a population-based case-control study in Scandinavia. J Natl Cancer Inst 2006, 98:1321-1330.
    • (2006) J Natl Cancer Inst , vol.98 , pp. 1321-1330
    • Landgren, O.1    Engels, E.A.2    Pfeiffer, R.M.3
  • 40
    • 80051590648 scopus 로고    scopus 로고
    • Risk of blood cancers among patients with chronic idiopathic thrombocytopenic purpura (ITP) [abstract]
    • s
    • Bennett I., Forssen U., Enger C., Nelson J. Risk of blood cancers among patients with chronic idiopathic thrombocytopenic purpura (ITP) [abstract]. EHA Annual Meeting Abstracts 2008, 93(s1):1449.
    • (2008) EHA Annual Meeting Abstracts , vol.93 , Issue.1 , pp. 1449
    • Bennett, I.1    Forssen, U.2    Enger, C.3    Nelson, J.4
  • 42
    • 70449726874 scopus 로고    scopus 로고
    • Effect of the nonpeptide thrombopoietin receptor agonist eltrombopag on bone marrow cells from patients with acute myeloid leukemia and myelodysplastic syndrome
    • Will B., Kawahara M., Luciano J.P., et al. Effect of the nonpeptide thrombopoietin receptor agonist eltrombopag on bone marrow cells from patients with acute myeloid leukemia and myelodysplastic syndrome. Blood 2009, 114:3899-3908.
    • (2009) Blood , vol.114 , pp. 3899-3908
    • Will, B.1    Kawahara, M.2    Luciano, J.P.3
  • 43
    • 0033485568 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled study with pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) as an adjunct to chemotherapy for adults with de novo acute myeloid leukemia
    • Archimbaud E., Ottoman O.G., Yin J.A., et al. A randomized, double-blind, placebo-controlled study with pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) as an adjunct to chemotherapy for adults with de novo acute myeloid leukemia. Blood 1999, 94:3694-3701.
    • (1999) Blood , vol.94 , pp. 3694-3701
    • Archimbaud, E.1    Ottoman, O.G.2    Yin, J.A.3
  • 44
    • 0035886697 scopus 로고    scopus 로고
    • Safety and efficacy of romiplostim in patients with lower-risk myelodysplastic syndrome and thrombocytopenia. Epub 2009 December 14,10.1200/JCO.2009.24.7999. Available from
    • Kantarjian H, Fenaux P, Sekeres MA, et al. Safety and efficacy of romiplostim in patients with lower-risk myelodysplastic syndrome and thrombocytopenia. J Clin Oncol. Epub 2009 December 14,10.1200/JCO.2009.24.7999. Available from: http://jco.ascopubs.org.
    • J Clin Oncol
    • Kantarjian, H.1    Fenaux, P.2    Sekeres, M.A.3
  • 45
    • 77953900978 scopus 로고    scopus 로고
    • Randomized phase II study evaluating the efficacy and safety of romiplostim treatment of patients with low or intermediate risk myelodysplastic syndrome (MDS) receiving lenalidomide [abstract]
    • Lyons R.M., Larson R.A., Kosmo M.A., et al. Randomized phase II study evaluating the efficacy and safety of romiplostim treatment of patients with low or intermediate risk myelodysplastic syndrome (MDS) receiving lenalidomide [abstract]. ASH Annual Meeting Abstracts 2009, 114:1770.
    • (2009) ASH Annual Meeting Abstracts , vol.114 , pp. 1770
    • Lyons, R.M.1    Larson, R.A.2    Kosmo, M.A.3
  • 46
    • 66749128758 scopus 로고    scopus 로고
    • Effect of romiplostim in patients with low or intermediate risk myelodysplastic syndrome (MDS) receiving azacytidine [abstract]
    • Kantarjian H., Giles F., Greenberg P., et al. Effect of romiplostim in patients with low or intermediate risk myelodysplastic syndrome (MDS) receiving azacytidine [abstract]. ASH Annual Meeting Abstracts 2008, 112:224.
    • (2008) ASH Annual Meeting Abstracts , vol.112 , pp. 224
    • Kantarjian, H.1    Giles, F.2    Greenberg, P.3
  • 47
    • 77953887831 scopus 로고    scopus 로고
    • Efficacy and safety of romiplostim in patients with low or intermediate-risk myelodysplastic syndrome (MDS) receiving decitabine [abstract]
    • Greenberg P.L., Garcia-Manero G., Moore M.R., et al. Efficacy and safety of romiplostim in patients with low or intermediate-risk myelodysplastic syndrome (MDS) receiving decitabine [abstract]. ASH Annual Meeting Abstracts 2009, 114:1769.
    • (2009) ASH Annual Meeting Abstracts , vol.114 , pp. 1769
    • Greenberg, P.L.1    Garcia-Manero, G.2    Moore, M.R.3
  • 48
    • 0037100423 scopus 로고    scopus 로고
    • Effects of pegylated recombinant human megakaryocyte growth and development factor in patients with idiopathic thrombocytopenic purpura
    • Nomura S., Dan K., Hotta T., Fujimura K., Ikeda Y. Effects of pegylated recombinant human megakaryocyte growth and development factor in patients with idiopathic thrombocytopenic purpura. Blood 2002, 100:728-730.
    • (2002) Blood , vol.100 , pp. 728-730
    • Nomura, S.1    Dan, K.2    Hotta, T.3    Fujimura, K.4    Ikeda, Y.5
  • 49
    • 0035469813 scopus 로고    scopus 로고
    • Thrombopoietin therapy increases platelet yields in healthy platelet donors
    • Kuter D.J., Goodnough L.T., Romo J., et al. Thrombopoietin therapy increases platelet yields in healthy platelet donors. Blood 2001, 98:1339-1345.
    • (2001) Blood , vol.98 , pp. 1339-1345
    • Kuter, D.J.1    Goodnough, L.T.2    Romo, J.3
  • 50
    • 0035760892 scopus 로고    scopus 로고
    • Thrombocytopenia caused by the development of antibodies to thrombopoietin
    • Li J., Yang C., Xia Y., et al. Thrombocytopenia caused by the development of antibodies to thrombopoietin. Blood 2001, 98:3241-3248.
    • (2001) Blood , vol.98 , pp. 3241-3248
    • Li, J.1    Yang, C.2    Xia, Y.3
  • 51
    • 77953902678 scopus 로고    scopus 로고
    • Evaluation of hepatobiliary parameters during eltrombopag treatment in patients with chronic immune thrombocytopenic purpura [abstract]
    • Maddrey W.C., Cheng G., Khelif A., Wroblewski S.L., Brainsky A. Evaluation of hepatobiliary parameters during eltrombopag treatment in patients with chronic immune thrombocytopenic purpura [abstract]. ASH Annual Meeting Abstracts 2009, 114:2410.
    • (2009) ASH Annual Meeting Abstracts , vol.114 , pp. 2410
    • Maddrey, W.C.1    Cheng, G.2    Khelif, A.3    Wroblewski, S.L.4    Brainsky, A.5
  • 52
    • 36549047972 scopus 로고    scopus 로고
    • Eltrombopag for thrombocytopenia in patients with cirrhosis associated with hepatitis C
    • McHutchison J.G., Dusheiko G., Shiffman M.L., et al. Eltrombopag for thrombocytopenia in patients with cirrhosis associated with hepatitis C. N Engl J Med 2007, 357:2227-2236.
    • (2007) N Engl J Med , vol.357 , pp. 2227-2236
    • McHutchison, J.G.1    Dusheiko, G.2    Shiffman, M.L.3
  • 53
    • 0035353206 scopus 로고    scopus 로고
    • Morbidity and mortality in adults with idiopathic thrombocytopenic purpura
    • Portielje J.E., Westendorp R.G., Kluin-Nelemans H.C., Brand A. Morbidity and mortality in adults with idiopathic thrombocytopenic purpura. Blood 2001, 97:2549-2554.
    • (2001) Blood , vol.97 , pp. 2549-2554
    • Portielje, J.E.1    Westendorp, R.G.2    Kluin-Nelemans, H.C.3    Brand, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.