Persistence of full-length caspase-12 and its relation to malaria in West and Central African populations

European Cytokine Network

Volumn 21, Issue 2, 2010, Pages 77-83

  McCall, Matthew B B ^a   Ferwerda, Bart ^a   Hopman, Joost ^a   Ploemen, Ivo ^a   Maiga, Boubacar ^b   Daou, Modibo ^b   Dolo, Amagana ^b   Hermsen, Cornelus C ^a   Doumbo, Ogobara K ^b   Bedu Addo, George ^c   Van Der Meer, Jos W ^a   Troye Blomberg, Marita ^d   Van Der Ven, André J A M ^a   Schumann, Ralf R ^e   Sauerwein, Robert W ^a   Mockenhaupt, Frank P ^e   Netea, Mihai G ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF BAMAKO   (Mali)

^c KWAME NKRUMAH UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Ghana)

^d STOCKHOLM UNIVERSITY   (Sweden)

^e CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Caspase 12; Cytokines; Genetic selection; P. falciparum malaria; Pregnancy

Indexed keywords

CASPASE 12; GAMMA INTERFERON;

ADOLESCENT; ADULT; AFRICA; ARTICLE; CENTRAL AFRICA; CHILD; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENE FREQUENCY; GENETIC DRIFT; GENOTYPE; HETEROZYGOTE; HOMOZYGOTE; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALARIA; MALARIA FALCIPARUM; MALE; MONONUCLEAR CELL; NONHUMAN; OBSTETRICS; PARAMETER; PERINATAL MORTALITY; PLASMODIUM; PLASMODIUM FALCIPARUM; POPULATION; PREGNANCY OUTCOME; PRESCHOOL CHILD; PREVALENCE; SCHOOL CHILD;

AFRICA, CENTRAL; AFRICA, WESTERN; ALLELES; CASPASE 12; FEMALE; GENOTYPE; HUMANS; MALARIA, FALCIPARUM; MALE; PREGNANCY; PREGNANCY COMPLICATIONS, PARASITIC;

PLASMODIUM FALCIPARUM;

EID: 77953883725     PISSN: 11485493     EISSN: None     Source Type: Journal    
DOI: 10.1684/ecn.2010.0187     Document Type: Article

References (35)

1. Lamkanfi M, Kalai M, Vandenabeele P. Caspase-12: an overview. Cell Death Differ 2004; 11: 365-8.
2. Roy S, Sharom JR, Houde C, et al. Confinement of caspase-12 proteolytic activity to autoprocessing. Proc Natl Acad Sci USA 2008; 105: 4133-8.
3. Scott AM, Saleh M. The inflammatory caspases: guardians against infections and sepsis. Cell Death Differ 2007; 14: 23-31. (Pubitemid 44911891)
4. LeBlanc PM, Yeretssian G, Rutherford N, et al. Caspase-12 modulates NOD signaling and regulates antimicrobial peptide production and mucosal immunity. Cell Host Microbe 2008; 3: 146-57. (Pubitemid 351325760)
5. Saleh M, Mathison JC, Wolinski MK, et al. Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice. Nature 2006; 440: 1064-8.
6. Eckhart L, Ballaun C, Hermann M, et al. Identification of novel mammalian caspases reveals an important role of gene loss in shaping the human caspase repertoire. Mol Biol Evol 2008; 25: 831-41.
7. Saleh M, Vaillancourt JP, Graham RK, et al. Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms. Nature 2004; 429: 75-9.
8. Kachapati K, O'Brien TR, Bergeron J, et al. Population distribution of the functional caspase-12 allele. Hum Mutat 2006; 27: 975.
9. Xue Y, Daly A, Yngvadottir B, et al. Spread of an inactive form of caspase-12 in humans is due to recent positive selection. Am J Hum Genet 2006; 78: 659-70.
10. Kwiatkowski DP. How malaria has affected the human genome and what human genetics can teach us about malaria. Am J Hum Genet 2005; 77: 171-92.
11. Flint J, Harding RM, Clegg JB, et al. Why are some genetic diseases common? Distinguishing selection from other processes by molecular analysis of globin gene variants. Hum Genet 1993; 91: 91-117. (Pubitemid 23159164)
12. Bennett S, Allen SJ, Olerup O, et al. Human leucocyte antigen (HLA) and malaria morbidity in a Gambian community. Trans R Soc Trop Med Hyg 1993; 87: 286-7. (Pubitemid 23212359)
13. Hill AV, Allsopp CE, Kwiatkowski D, et al. Common west HLA antigens are associated with protection from severe malaria. Nature 1991; 352: 595-600. (Pubitemid 21912384)
14. Ferwerda B, McCall MB, Alonso S, et al. TLR4 polymorphisms, infectious diseases, and evolutionary pressure during migration of modern humans. Proc Natl Acad Sci U S A 2007; 104: 16645-50.
15. Khor CC, Chapman SJ, Vannberg FO, et al. A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis. Nat Genet 2007; 39: 523-8.
16. McGuire W, Hill AV, Allsopp CE, et al. Variation in the TNF-alpha promoter region associated with susceptibility to cerebral malaria. Nature 1994; 371: 508-10.
17. Mockenhaupt FP, Hamann L, von GC, et al. Common polymorphisms of toll-like receptors 4 and 9 are associated with the clinical manifestation of malaria during pregnancy. J Infect Dis 2006; 194: 184-8.
18. Mockenhaupt FP, Cramer JP, Hamann L, et al. Toll-like receptor (TLR) polymorphisms in African children: Common TLR-4 variants predispose to severe malaria. Proc Natl Acad Sci USA 2006; 103: 177-82.
19. Dolo A, Modiano D, Maiga B, et al. Difference in susceptibility to malaria between two sympatric ethnic groups in Mali. Am J Trop Med Hyg 2005; 72: 243-8.
20. Hermsen CC, Konijnenberg Y, Mulder L, et al. Circulating concentrations of soluble granzyme A and B increase during natural and experimental Plasmodium falciparum infections. Clin Exp Immunol 2003; 132: 467-72.
21. Severe falciparum malaria. World Health Organization, Communicable Diseases Cluster. Trans R Soc Trop Med Hyg 2000; 94 (Suppl. 1): S1-90.
22. Mockenhaupt FP, Bedu-Addo G, von Gaertner C, et al. Detection and clinical manifestation of placental malaria in southern Ghana. Malar J 2006; 5: 119.
23. Snounou G, Viriyakosol S, Zhu XP, et al. High sensitivity of detection of human malaria parasites by the use of nested polymerase chain reaction. Mol Biochem Parasitol 1993; 61: 315-20.
24. Finnstrom O. Studies on maturity in newborn infants. IX. Further observations on the use of external characteristics in estimating gestational age. Acta Paediatr Scand 1977; 66: 601-4.
25. Ghayur T, Banerjee S, Hugunin M, et al. Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production. Nature 1997; 386: 619-23.
26. Gu Y, Kuida K, Tsutsui H, et al. Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme. Science 1997; 275: 206-9.
27. Mackintosh CL, Beeson JG, Marsh K. Clinical features and pathogenesis of severe malaria. Trends Parasitol 2004; 20: 597-603.
28. Kossodo S, Monso C, Juillard P, et al. Interleukin-10 modulates susceptibility in experimental cerebral malaria. Immunology 1997; 91: 536-40.
29. Li C, Corraliza I, Langhorne J. A defect in interleukin-10 leads to enhanced malarial disease in Plasmodium chabaudi chabaudi infection in mice. Infect Immun 1999; 67: 4435-42. (Pubitemid 29400417)
30. Awandare GA, Goka B, Boeuf P, et al. Increased levels of inflammatory mediators in children with severe Plasmodium falciparum malaria with respiratory distress. J Infect Dis 2006; 194: 1438-46. (Pubitemid 44706513)
31. Day NP, Hien TT, Schollaardt T, et al. The prognostic and pathophysiologic role of pro- and antiinflammatory cytokines in severe malaria. J Infect Dis 1999; 180: 1288-97. (Pubitemid 30070216)
32. John CC, Opika-Opoka R, Byarugaba J, et al. Low levels of RANTES are associated with mortality in children with cerebral malaria. J Infect Dis 2006; 194: 837-45. (Pubitemid 44344133)
33. Kurtzhals JA, Adabayeri V, Goka BQ, et al. Low plasma concentrations of interleukin 10 in severe malarial anaemia compared with cerebral and uncomplicated malaria. Lancet 1998; 351: 1768-72. (Pubitemid 28269187)
34. May J, Lell B, Luty AJ, et al. Plasma interleukin-10: Tumor necrosis factor (TNF)-alpha ratio is associated with TNF promoter variants and predicts malarial complications. J Infect Dis 2000; 182: 1570-3.
35. Lyke KE, Burges R, Cissoko Y, et al. Serum levels of the proinflammatory cytokines interleukin-1 beta (IL-1beta), IL-6, IL-8, IL-10, tumor necrosis factor alpha, and IL-12(p70) in Malian children with severe Plasmodium falciparum malaria and matched uncomplicated malaria or healthy controls. Infect Immun 2004; 72: 5630-7.