Antifungal activity of the essential oil of thymus x viciosoi against candida, cryptococcus, aspergillus and dermatophyte species

Planta Medica

Volumn 76, Issue 9, 2010, Pages 882-888

  Vale Silva, Luís André ^a   Gonçalves, Maria José ^b   Cavaleiro, Carlos ^b   Salgueiro, Lígia ^b   Pinto, Eugénia ^a  

^a UNIVERSITY OF PORTO   (Portugal)

^b UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

antifungal activity; Candida albicans; cytoplasmic membrane disruption; flow cytometry; Lamiaceae; phenolic oil; Thymus x viciosoi (Pau) R. Morales

Indexed keywords

CARVACROL; ESSENTIAL OIL; PARA CYMENE; THYMOL;

ANGIOSPERM; ANTIFUNGAL ACTIVITY; ARTICLE; ASPERGILLUS; CANDIDA ALBICANS; CELL DEATH; CELL MEMBRANE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CRYPTOCOCCUS; DERMATOPHYTE; FLOW CYTOMETRY; FUNGICIDAL ACTIVITY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; THYMUS X VICIOSOI;

ANTIFUNGAL AGENTS; ARTHRODERMATACEAE; CANDIDA; CRYPTOCOCCUS; MICROBIAL SENSITIVITY TESTS; OILS, VOLATILE; PLANT EXTRACTS; THYMUS PLANT;

ASPERGILLUS; CANDIDA; CANDIDA ALBICANS; LAMIACEAE; THYMUS (THYME);

EID: 77953864483     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0029-1240799     Document Type: Article

References (25)

1. Richardson M, Lass-Florl C. Changing epidemiology of systemic fungal infections. Clin Microbiol Infect 2008 14 (Suppl.4) 5-24
2. Edmond M B., Wallace S E., McClish D K., Pfaller M A., Jones R N., Wenzel R P. Nosocomial bloodstream infections in United States hospitals: a three-year analysis. Clin Infect Dis 1999 29 239-244
3. Eggimann P, Garbino J, Pittet D. Epidemiology of Candida species infections in critically ill non-immunosuppressed patients. Lancet Infect Dis 2003 3 685-702
4. Gupta A K., Cooper E A. Update in antifungal therapy of dermatophytosis. Mycopathologia 2008 166 353-367
5. de Pauw B E., Picazo J J. Present situation in the treatment of invasive fungal infection. Int J Antimicrob Agents 2008 32 (Suppl. 2) S167-S171
6. Pauli A. Anticandidal low molecular compounds from higher plants with special reference to compounds from essential oils. Med Res Rev 2006 26 223-268
7. Edris A E. Pharmaceutical and therapeutic potentials of essential oils and their individual volatile constituents: a review. Phytother Res 2007 21 308-323
8. Kalemba D, Kunicka A. Antibacterial and antifungal properties of essential oils. Curr Med Chem 2003 10 813-829
9. Bakkali F, Averbeck S, Averbeck D, Idaomar M. Biological effects of essential oils a review. Food Chem Toxicol 2008 46 446-475
10. Figueiredo A C., Barroso J G., Pedro L G., Salgueiro L, Miguel M G., Faleiro M L. Portuguese Thymbra and Thymus species volatiles: chemical composition and biological activities. Curr Pharm Des 2008 14 3120-3140
11. Pina-Vaz C, Rodrigues A G., Pinto E, Costa-de-Oliveira S, Tavares C, Salgueiro L, Cavaleiro C, Gonçalves M J., Martinez-de-Oliveira J. Antifungal activity of Thymus oils and their major compounds. J Eur Acad Dermatol Venereol 2004 18 73-78
12. Pinto E, Pina-Vaz C, Salgueiro L, Gonçalves M J., Costa-de-Oliveira S, Cavaleiro C, Palmeira A, Rodrigues A, Martinez-de-Oliveira J. Antifungal activity of the essential oil of Thymus pulegioides on Candida, Aspergillus and dermatophyte species. J Med Microbiol 2006 55 1367-1373 (Pubitemid 44651663)
13. Salgueiro L R., Pinto E, Goncalves M J., Costa I, Palmeira A, Cavaleiro C, Pina-Vaz C, Rodrigues A G., Martinez-de-Oliveira J. Antifungal activity of the essential oil of Thymus capitellatus against Candida, Aspergillus and dermatophyte strains. Flavour Fragrance J 2006 21 749-753 (Pubitemid 44349528)
14. Sokovic M, Glamoclija J, Ciric A, Kataranovski D, Marin P D., Vukojevic J, Brkic D. Antifungal activity of the essential oil of Thymus vulgaris L. and thymol on experimentally induced dermatomycoses. Drug Dev Ind Pharm 2008 34 1388-1393
15. das Neves J, Pinto E, Teixeira B, Dias G, Rocha P, Cunha T, Santos B, Amaral M H., Bahia M F. Local treatment of vulvovaginal candidosis general and practical considerations. Drugs 2008 68 1787-1802
16. Saville S P., Lazzell A L., Bryant A P., Fretzen A, Monreal A, Solberg E O., Monteagudo C, Lopez-Ribot J L., Milne G T. Inhibition of filamentation can be used to treat disseminated candidiasis. Antimicrob Agents Chemother 2006 50 3312-3316
17. Adams R P. Identification of essential oil components by gas chromatography/mass spectroscopy. Carol Stream Allured Publishing Corporation 2004
18. Joulain D, Konig W A. The atlas of spectral data of sesquiterpene hydrocarbons. Hamburg E. B. Verlag Hamburg 1998
19. Clinical and Laboratory Standards Institute (CLSI). Reference method for broth dilution antifungal susceptibility testing of yeasts; Approved standard, third edition M27-A3. Wayne Clinical and Laboratory Standards Institute 2008
20. Clinical and Laboratory Standards Institute (CLSI). Reference method for broth dilution antifungal susceptibility testing of yeasts, third informational supplement M27-S3. Wayne Clinical and Laboratory Standards Institute 2008
21. Clinical and Laboratory Standards Institute (CLSI). Reference method for broth dilution antifungal susceptibility testing of filamentous fungi; approved standard, second edition M38-A2. Wayne Clinical and Laboratory Standards Institute 2008
22. Marichal P, Gorrens J, Vancutsem J, Vandenbossche H. Culture media for the study of the effects of azole derivatives on germ tube formation and hyphal growth of Candida albicans. Mykosen 1986 29 76-81
23. Mitchell A P. Dimorphism and virulence in Candida albicans. Curr Opin Microbiol 1998 1 687-692
24. Millard P J., Roth B L., Thi H P., Yue S T., Haugland R P. Development of the FUN-1 family of fluorescent probes for vacuole labeling and viability testing of yeasts. Appl Environ Microbiol 1997 63 2897-2905
25. Pinto E, Queiroz M J., Vale-Silva L A., Oliveira J F., Begouin A, Begouin J M., Kirsch G. Antifungal activity of synthetic di(hetero)arylamines based on the benzo[b]thiophene moiety. Bioorg Med Chem 2008 16 8172-8177