메뉴 건너뛰기




Volumn 5, Issue 3, 2010, Pages 309-323

Pitavastatin: A distinctive lipid-lowering drug

Author keywords

cardiovascularb disease; dyslipidemia; hydroxymethylglutaryl coA reductase inhibitor; pitavastatin; primary hypercholesterolemia

Indexed keywords

APOLIPOPROTEIN A1; APOLIPOPROTEIN B; ATORVASTATIN; BEZAFIBRATE; CERIVASTATIN; CYCLOSPORIN A; CYTOCHROME P450 3A4; DIGOXIN; EZETIMIBE; FENOFIBRATE; FLUINDOSTATIN; GEMFIBROZIL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; ITRACONAZOLE; LACTONE; MEVINOLIN; PITAVASTATIN; PRAVASTATIN; ROSUVASTATIN; SIMVASTATIN; TRIACYLGLYCEROL;

EID: 77953819724     PISSN: 17460875     EISSN: None     Source Type: Journal    
DOI: 10.2217/clp.10.28     Document Type: Review
Times cited : (16)

References (63)
  • 1
    • 70450081001 scopus 로고    scopus 로고
    • Major lipids, apolipoproteins, and risk of vascular disease
    • Emerging Risk Factors Collaboration
    • Di Angelantonio E, Sarwar N, Perry P et al.; Emerging Risk Factors Collaboration: Major lipids, apolipoproteins, and risk of vascular disease. JAMA 302, 1993-2000 (2009).
    • (2009) JAMA , vol.302 , pp. 1993-2000
    • Di Angelantonio, E.1    Sarwar, N.2    Perry, P.3
  • 2
    • 26244432388 scopus 로고    scopus 로고
    • Efficacy and safety of cholesterol-lowering treatment: Prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins
    • Cholesterol Treatment Trialists' (CTT) Collaborators
    • Baigent C, Keech A, Kearney PM et al.; Cholesterol Treatment Trialists' (CTT) Collaborators: Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins. Lancet 366, 1267-1278 (2005).
    • (2005) Lancet , vol.366 , pp. 1267-1278
    • Baigent, C.1    Keech, A.2    Kearney, P.M.3
  • 3
    • 9644252909 scopus 로고    scopus 로고
    • Incidence of hospitalized rhabdomyolysis in patients treated with lipid-lowering drugs
    • Graham DJ, Staffa JA, Shatin D et al.: Incidence of hospitalized rhabdomyolysis in patients treated with lipid-lowering drugs. JAMA 292, 2585-2590 (2004).
    • (2004) JAMA , vol.292 , pp. 2585-2590
    • Graham, D.J.1    Staffa, J.A.2    Shatin, D.3
  • 4
    • 33645875021 scopus 로고    scopus 로고
    • Statin safety: An assessment using an administrative claims database
    • Cziraky MJ, Willey VJ, McKenney JM et al.: Statin safety: an assessment using an administrative claims database. Am. J. Cardiol. 97, 61C-68C (2006).
    • (2006) Am. J. Cardiol. , vol.97
    • Cziraky, M.J.1    Willey, V.J.2    McKenney, J.M.3
  • 5
    • 0034266349 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitors: Assessing differences in drug interactions and safety profiles
    • Beaird SL: HMG-CoA reductase inhibitors: assessing differences in drug interactions and safety profiles. J. Am. Pharm. Assoc. 40, 637-644 (2000).
    • (2000) J. Am. Pharm. Assoc. , vol.40 , pp. 637-644
    • Beaird, S.L.1
  • 7
    • 42149184153 scopus 로고    scopus 로고
    • ApoB/ApoA1 ratio and subclinical atherosclerosis
    • Panayiotou A, Griffin M, Georgiou N et al.: ApoB/ApoA1 ratio and subclinical atherosclerosis. Int. Angiol. 27, 74-80 (2008).
    • (2008) Int. Angiol. , vol.27 , pp. 74-80
    • Panayiotou, A.1    Griffin, M.2    Georgiou, N.3
  • 8
    • 0037524291 scopus 로고    scopus 로고
    • Effectiveness of statin titration on low-density lipoprotein cholesterol goal attainment in patients at high risk of atherogenic events
    • Foley KA, Simpson RJ Jr, Crouse JR III, Weiss TW, Markson LE, Alexander CM: Effectiveness of statin titration on low-density lipoprotein cholesterol goal attainment in patients at high risk of atherogenic events. Am. J. Cardiol. 92, 79-81 (2003).
    • (2003) Am. J. Cardiol. , vol.92 , pp. 79-81
    • Foley, K.A.1    Simpson Jr., R.J.2    Crouse III, J.R.3    Weiss, T.W.4    Markson, L.E.5    Alexander, C.M.6
  • 9
    • 57749179983 scopus 로고    scopus 로고
    • Prevalence and predictors of lipid abnormalities in patients treated with statins in the UK general practice
    • Phatak H, Wentworth C, Sazonov V, Burke T: Prevalence and predictors of lipid abnormalities in patients treated with statins in the UK general practice. Atherosclerosis 202, 225-233 (2009).
    • (2009) Atherosclerosis , vol.202 , pp. 225-233
    • Phatak, H.1    Wentworth, C.2    Sazonov, V.3    Burke, T.4
  • 10
    • 52949154682 scopus 로고    scopus 로고
    • A large-scale, long-term, prospective post-marketing surveillance of pitavastatin (LIVALO Tablet): LIVALO Effectiveness and Safety (LIVES) study
    • Kurihara Y, Douzono T, Kawakita K, Nagasaki Y: A large-scale, long-term, prospective post-marketing surveillance of pitavastatin (LIVALO Tablet): LIVALO Effectiveness and Safety (LIVES) study. Jpn Pharmacol. Ther. 36, 709-731 (2008).
    • (2008) Jpn Pharmacol. Ther. , vol.36 , pp. 709-731
    • Kurihara, Y.1    Douzono, T.2    Kawakita, K.3    Nagasaki, Y.4
  • 12
    • 0028929401 scopus 로고
    • Pharmacology of competitive inhibitors of HMG-CoA reductase
    • Corsini A, Maggi FM, Catapano AL: Pharmacology of competitive inhibitors of HMG-CoA reductase. Pharmacol. Res. 31, 9-27 (1995).
    • (1995) Pharmacol. Res. , vol.31 , pp. 9-27
    • Corsini, A.1    Maggi, F.M.2    Catapano, A.L.3
  • 13
    • 33748042671 scopus 로고    scopus 로고
    • Pharmacokinetic and pharmacodynamic alterations of 3-hydroxy- 3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors: Drug-drug interactions and interindividual differences in transporter and metabolic enzyme functions
    • Shitara Y, Sugiyama Y: Pharmacokinetic and pharmacodynamic alterations of 3-hydroxy- 3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors: drug-drug interactions and interindividual differences in transporter and metabolic enzyme functions. Pharmacol. Ther. 112, 71-105 (2006).
    • (2006) Pharmacol. Ther. , vol.112 , pp. 71-105
    • Shitara, Y.1    Sugiyama, Y.2
  • 14
    • 33646536542 scopus 로고    scopus 로고
    • Drug and bile acid transporters in rosuvastatin hepatic uptake: Function, expression, and pharmacogenetics
    • Ho RH, Tirona RG, Leake BF et al.: Drug and bile acid transporters in rosuvastatin hepatic uptake: function, expression, and pharmacogenetics. Gastroenterology 130, 1793-1806 (2006).
    • (2006) Gastroenterology , vol.130 , pp. 1793-1806
    • Ho, R.H.1    Tirona, R.G.2    Leake, B.F.3
  • 15
    • 0033601257 scopus 로고    scopus 로고
    • A novel human hepatic organic anion transporting polypeptide (OATP2) Identification of a liver-specific human organic anion transporting polypeptide and identification of rat and human hydroxymethylglutaryl- CoA reductase inhibitor transporters
    • Hsiang B, Zhu Y, Wang Z et al.: A novel human hepatic organic anion transporting polypeptide (OATP2) Identification of a liver-specific human organic anion transporting polypeptide and identification of rat and human hydroxymethylglutaryl- CoA reductase inhibitor transporters. J. Biol. Chem. 274, 37161-37168 (1999).
    • (1999) J. Biol. Chem. , vol.274 , pp. 37161-37168
    • Hsiang, B.1    Zhu, Y.2    Wang, Z.3
  • 16
    • 34547178337 scopus 로고    scopus 로고
    • Substrate-dependent drug-drug interactions between gemfibrozil, fluvastatin and other organic anion-transporting peptide (OATP) substrates on OATP1B1, OATP2B1, and OATP1B3
    • Noé J, Portmann R, Brun ME, Funk C: Substrate-dependent drug-drug interactions between gemfibrozil, fluvastatin and other organic anion-transporting peptide (OATP) substrates on OATP1B1, OATP2B1, and OATP1B3. Drug Metab. Dispos. 35, 1308-1314 (2007).
    • (2007) Drug Metab. Dispos. , vol.35 , pp. 1308-1314
    • Noé, J.1    Portmann, R.2    Brun, M.E.3    Funk, C.4
  • 17
    • 0012908222 scopus 로고    scopus 로고
    • Pharmacological profile of a novel synthetic inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase
    • Aoki T, Nishimura H, Nakagawa S et al.: Pharmacological profile of a novel synthetic inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. Arzneimittelforschung 47, 904-909 (1997).
    • (1997) Arzneimittelforschung , vol.47 , pp. 904-909
    • Aoki, T.1    Nishimura, H.2    Nakagawa, S.3
  • 18
    • 0034570787 scopus 로고    scopus 로고
    • Relative induction of mRNA for HMG CoA reductase and LDL receptor by five different HMG-CoA reductase inhibitors in cultured human cells
    • Morikawa S, Umetani M, Nakagawa S et al.: Relative induction of mRNA for HMG CoA reductase and LDL receptor by five different HMG-CoA reductase inhibitors in cultured human cells. J. Atheroscler. Thromb. 7, 138-144 (2000).
    • (2000) J. Atheroscler. Thromb. , vol.7 , pp. 138-144
    • Morikawa, S.1    Umetani, M.2    Nakagawa, S.3
  • 20
    • 5144220807 scopus 로고    scopus 로고
    • Effect of pitavastatin on apolipoprotein A-I production in HepG2 cell
    • Maejima T, Yamazaki H, Aoki T et al.: Effect of pitavastatin on apolipoprotein A-I production in HepG2 cell. Biochem. Biophys. Res. Commun. 324, 835-839 (2004).
    • (2004) Biochem. Biophys. Res. Commun. , vol.324 , pp. 835-839
    • Maejima, T.1    Yamazaki, H.2    Aoki, T.3
  • 21
    • 33845420011 scopus 로고    scopus 로고
    • Drug interactions with lipid-lowering drugs: Mechanisms and clinical relevance
    • Neuvonen PJ, Niemi M, Backman JT: Drug interactions with lipid-lowering drugs: mechanisms and clinical relevance. Clin. Pharmacol. Ther. 80, 565-581 (2006).
    • (2006) Clin. Pharmacol. Ther. , vol.80 , pp. 565-581
    • Neuvonen, P.J.1    Niemi, M.2    Backman, J.T.3
  • 22
    • 0001224909 scopus 로고    scopus 로고
    • Studies on the Metabolic Fate of NK-104, a new inhibitor of HMG-CoA reductase (5) in vitro metabolism and plasma protein binding in animals and human
    • Fujino H, Yamada I, Kojima J, Hirano M, Matsumoto H, Yoneda M: Studies on the Metabolic Fate of NK-104, a new inhibitor of HMG-CoA reductase (5) in vitro metabolism and plasma protein binding in animals and human. Xenob. Metab. Dis. 14, 415-424 (1999).
    • (1999) Xenob. Metab. Dis. , vol.14 , pp. 415-424
    • Fujino, H.1    Yamada, I.2    Kojima, J.3    Hirano, M.4    Matsumoto, H.5    Yoneda, M.6
  • 23
    • 0030953045 scopus 로고    scopus 로고
    • Pharmacodynamics and pharmacokinetics of the HMG-CoA reductase inhibitors. Similarities and differences
    • Lennernäs H, Fager G: Pharmacodynamics and pharmacokinetics of the HMG-CoA reductase inhibitors. Similarities and differences. Clin. Pharmacokinet. 32, 403-425 (1997).
    • (1997) Clin. Pharmacokinet. , vol.32 , pp. 403-425
    • Lennernäs, H.1    Fager, G.2
  • 24
    • 0036708020 scopus 로고    scopus 로고
    • A review of the pharmacologic and pharmacokinetic aspects of rosuvastatin
    • White CM: A review of the pharmacologic and pharmacokinetic aspects of rosuvastatin. J. Clin. Pharmacol. 42, 963-970 (2002).
    • (2002) J. Clin. Pharmacol. , vol.42 , pp. 963-970
    • White, C.M.1
  • 25
    • 0042531819 scopus 로고    scopus 로고
    • Metabolic fate of pitavastatin, a new inhibitor of HMG-CoA reductase: Similarities and difference in the metabolism of pitavastatin in monkeys and humans
    • Yamada I, Fujino H, Shimada S, Kojima J: Metabolic fate of pitavastatin, a new inhibitor of HMG-CoA reductase: similarities and difference in the metabolism of pitavastatin in monkeys and humans. Xenobiotica 33, 789-803 (2003).
    • (2003) Xenobiotica , vol.33 , pp. 789-803
    • Yamada, I.1    Fujino, H.2    Shimada, S.3    Kojima, J.4
  • 26
    • 4644364576 scopus 로고    scopus 로고
    • Contribution of OATP2 (OATP1B1) and OATP8 (OATP1B3) to the hepatic uptake of pitavastatin in humans
    • Hirano M, Maeda K, Shitara Y, Sugiyama Y: Contribution of OATP2 (OATP1B1) and OATP8 (OATP1B3) to the hepatic uptake of pitavastatin in humans. J. Pharmacol. Exp. Ther. 311, 139-146 (2004).
    • (2004) J. Pharmacol. Exp. Ther. , vol.311 , pp. 139-146
    • Hirano, M.1    Maeda, K.2    Shitara, Y.3    Sugiyama, Y.4
  • 28
    • 27444434929 scopus 로고    scopus 로고
    • Effects of grapefruit juice on the pharmacokinetics of pitavastatin and atorvastatin
    • Ando H, Tsuruoka S, Yanagihara H et al.: Effects of grapefruit juice on the pharmacokinetics of pitavastatin and atorvastatin. Br. J. Clin. Pharmacol. 60, 494-497 (2005).
    • (2005) Br. J. Clin. Pharmacol. , vol.60 , pp. 494-497
    • Ando, H.1    Tsuruoka, S.2    Yanagihara, H.3
  • 29
    • 77952419584 scopus 로고    scopus 로고
    • Pitavastatin is not subject to clinically relevant pharmacokinetic interactions when administered with CYP3A4 inhibitors in healthy volunteers
    • Nakagawa S, Hounslow N: Pitavastatin is not subject to clinically relevant pharmacokinetic interactions when administered with CYP3A4 inhibitors in healthy volunteers. Eur. Heart J. 30(Abstract Suppl.), 958 (2009).
    • (2009) Eur. Heart J. , vol.30 , Issue.SUPPL. , pp. 958
    • Nakagawa, S.1    Hounslow, N.2
  • 30
    • 4644272415 scopus 로고    scopus 로고
    • An open-label study on the pharmacokinetics (PK) of pitavastatin (NK-104) when administered concomitantly with fenofibrate or gemfibrozil in healthy volunteers
    • Mathew P, Cuddy T, Tracewell WG, Salazar D: An open-label study on the pharmacokinetics (PK) of pitavastatin (NK-104) when administered concomitantly with fenofibrate or gemfibrozil in healthy volunteers. Clin. Pharmacol. Ther. 75, P33 (2004).
    • (2004) Clin. Pharmacol. Ther. , vol.75
    • Mathew, P.1    Cuddy, T.2    Tracewell, W.G.3    Salazar, D.4
  • 31
    • 0033758172 scopus 로고    scopus 로고
    • NK-104: A novel synthetic HMG-CoA reductase inhibitor
    • Kajinami K, Mabuchi H, Saito Y: NK-104: a novel synthetic HMG-CoA reductase inhibitor. Exp. Opin. Invest. Drugs 9, 2653-2661 (2000).
    • (2000) Exp. Opin. Invest. Drugs , vol.9 , pp. 2653-2661
    • Kajinami, K.1    Mabuchi, H.2    Saito, Y.3
  • 33
    • 0033678688 scopus 로고    scopus 로고
    • Atorvastatin coadministration may increase digoxin concentrations by inhibition of intestinal P-glycoprotein-mediated secretion
    • Boyd RA, Stern RH, Stewart BH et al.: Atorvastatin coadministration may increase digoxin concentrations by inhibition of intestinal P-glycoprotein- mediated secretion. J. Clin. Pharmacol. 40, 91-98 (2000).
    • (2000) J. Clin. Pharmacol. , vol.40 , pp. 91-98
    • Boyd, R.A.1    Stern, R.H.2    Stewart, B.H.3
  • 34
    • 34548103493 scopus 로고    scopus 로고
    • Role of OATP transporters in the disposition of drugs
    • Niemi M: Role of OATP transporters in the disposition of drugs. Pharmacogenomics 8, 787-802 (2007).
    • (2007) Pharmacogenomics , vol.8 , pp. 787-802
    • Niemi, M.1
  • 35
    • 4644301418 scopus 로고    scopus 로고
    • Gemfibrozil and its glucuronide inhibit the organic anion transporting polypeptide 2 (OATP2/OATP1B1:SLC21A6)-mediated hepatic uptake and CYP2C8-mediated metabolism of cerivastatin: Analysis of the mechanism of the clinically relevant drug-drug interaction between cerivastatin and gemfibrozil
    • Shitara Y, Hirano M, Sato H, Sugiyama Y: Gemfibrozil and its glucuronide inhibit the organic anion transporting polypeptide 2 (OATP2/OATP1B1:SLC21A6)- mediated hepatic uptake and CYP2C8-mediated metabolism of cerivastatin: analysis of the mechanism of the clinically relevant drug-drug interaction between cerivastatin and gemfibrozil. J. Pharmacol. Exp. Ther. 311, 228-236 (2004).
    • (2004) J. Pharmacol. Exp. Ther. , vol.311 , pp. 228-236
    • Shitara, Y.1    Hirano, M.2    Sato, H.3    Sugiyama, Y.4
  • 36
    • 3242789902 scopus 로고    scopus 로고
    • The drug-drug interactions of pitavastatin (NK-104), a novel HMG-CoA reductase inhibitor and cyclosporine
    • Hasunuma T, Masahiko N, Takashi Y et al.: The drug-drug interactions of pitavastatin (NK-104), a novel HMG-CoA reductase inhibitor and cyclosporine. J. Clin. Ther. Med. 19, 381-389 (2003).
    • (2003) J. Clin. Ther. Med. , vol.19 , pp. 381-389
    • Hasunuma, T.1    Masahiko, N.2    Takashi, Y.3
  • 37
    • 70350048926 scopus 로고    scopus 로고
    • Impact of OATP transporters on pharmacokinetics
    • Kalliokoski A, Niemi M: Impact of OATP transporters on pharmacokinetics. Br. J. Pharmacol. 158, 693-705 (2009).
    • (2009) Br. J. Pharmacol. , vol.158 , pp. 693-705
    • Kalliokoski, A.1    Niemi, M.2
  • 38
    • 68249161945 scopus 로고    scopus 로고
    • Imaging of cyclosporine inhibition of P-glycoprotein activity using 11C-verapamil in the brain: Studies of healthy humans
    • Muzi M, Mankoff DA, Link JM et al.: Imaging of cyclosporine inhibition of P-glycoprotein activity using 11C-verapamil in the brain: studies of healthy humans. J. Nucl. Med. 50, 1267-1275 (2009).
    • (2009) J. Nucl. Med. , vol.50 , pp. 1267-1275
    • Muzi, M.1    Mankoff, D.A.2    Link, J.M.3
  • 40
    • 0036231636 scopus 로고    scopus 로고
    • Clinical efficacy of pitavastatin, a new 3-hydroxy-3- methylglutaryl coenzyme A reductase inhibitor, in patients with hyperlipidemia. Dose-finding study using the double-blind, three-group parallel comparison
    • Saito Y, Yamada N, Teramoto T et al.: Clinical efficacy of pitavastatin, a new 3-hydroxy-3- methylglutaryl coenzyme A reductase inhibitor, in patients with hyperlipidemia. Dose-finding study using the double-blind, three-group parallel comparison. Arzneimittelforschung 52, 251-255 (2002).
    • (2002) Arzneimittelforschung , vol.52 , pp. 251-255
    • Saito, Y.1    Yamada, N.2    Teramoto, T.3
  • 41
    • 0027987849 scopus 로고
    • Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S)
    • Scandinavian Simvastatin Survival Study Group
    • Scandinavian Simvastatin Survival Study Group: Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S). Lancet 344, 1383-1389 (1994).
    • (1994) Lancet , vol.344 , pp. 1383-1389
  • 42
    • 67249088838 scopus 로고    scopus 로고
    • Pitavastatin compared with atorvastatin in primary hypercholesterolemia or combined dyslipidemia
    • Budinski D, Arneson V, Hounslow N, Gratsiansky N: Pitavastatin compared with atorvastatin in primary hypercholesterolemia or combined dyslipidemia. Clin. Lipidol. 4(3), 291-302 (2009).
    • (2009) Clin. Lipidol. , vol.4 , Issue.3 , pp. 291-302
    • Budinski, D.1    Arneson, V.2    Hounslow, N.3    Gratsiansky, N.4
  • 43
    • 72549107976 scopus 로고    scopus 로고
    • Comparison of pitavastatin with simvastatin in primary hypercholesterolaemia or combined dyslipidaemia
    • Ose L, Budinski D, Hounslow N, Arneson V: Comparison of pitavastatin with simvastatin in primary hypercholesterolaemia or combined dyslipidaemia. Curr. Med. Res. Opin. 25(11), 2755-2764 (2009).
    • (2009) Curr. Med. Res. Opin. , vol.25 , Issue.11 , pp. 2755-2764
    • Ose, L.1    Budinski, D.2    Hounslow, N.3    Arneson, V.4
  • 44
    • 77952420085 scopus 로고    scopus 로고
    • Long-term treatment with pitavastatin is effective and well tolerated by patients with primary hypercholesterolemia or combined dyslipidemia
    • doi:10.1016/j.atherosclerosis.2009.12.009 (Epub ahead of print)
    • Ose L, Budinski D, Hounslow N, Arneson V: Long-term treatment with pitavastatin is effective and well tolerated by patients with primary hypercholesterolemia or combined dyslipidemia. Atherosclerosis (2010), doi:10.1016/j.atherosclerosis.2009.12.009 (Epub ahead of print).
    • (2010) Atherosclerosis
    • Ose, L.1    Budinski, D.2    Hounslow, N.3    Arneson, V.4
  • 45
    • 67650095320 scopus 로고    scopus 로고
    • Effect of intensive statin therapy on regression of coronary atherosclerosis in patients with acute coronary syndrome: A multicenter randomized trial evaluated by volumetric intravascular ultrasound using pitavastatin versus atorvastatin (JAPAN-ACS [Japan assessment of pitavastatin and atorvastatin in acute coronary syndrome] study)
    • JAPAN-ACS investigators
    • Hiro T, Kimura T, Morimoto T et al.; JAPAN-ACS investigators: Effect of intensive statin therapy on regression of coronary atherosclerosis in patients with acute coronary syndrome: a multicenter randomized trial evaluated by volumetric intravascular ultrasound using pitavastatin versus atorvastatin (JAPAN-ACS [Japan assessment of pitavastatin and atorvastatin in acute coronary syndrome] study). J. Am. Coll. Cardiol. 54, 293-302 (2009).
    • (2009) J. Am. Coll. Cardiol. , vol.54 , pp. 293-302
    • Hiro, T.1    Kimura, T.2    Morimoto, T.3
  • 46
    • 69049092983 scopus 로고    scopus 로고
    • Early effect of lipid-lowering therapy with pitavastatin on regression of coronary atherosclerotic plaque. Comparison with atorvastatin
    • Toi T, Taguchi I, Yoneda S et al.: Early effect of lipid-lowering therapy with pitavastatin on regression of coronary atherosclerotic plaque. Comparison with atorvastatin. Circ. J. 73, 1466-1472 (2009).
    • (2009) Circ. J. , vol.73 , pp. 1466-1472
    • Toi, T.1    Taguchi, I.2    Yoneda, S.3
  • 48
    • 30944443950 scopus 로고    scopus 로고
    • Plasma lipoproteins and apolipoproteins as predictors of cardiovascular risk and treatment benefit in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER)
    • PROSPER Study Group
    • Packard CJ, Ford I, Robertson M et al.; PROSPER Study Group: Plasma lipoproteins and apolipoproteins as predictors of cardiovascular risk and treatment benefit in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER). Circulation 112, 3058-3065 (2005).
    • (2005) Circulation , vol.112 , pp. 3058-3065
    • Packard, C.J.1    Ford, I.2    Robertson, M.3
  • 49
    • 77953815835 scopus 로고    scopus 로고
    • Robust efficacy of pitavastatin and comparable safety to pravastatin
    • Stender S, Hounslow N: Robust efficacy of pitavastatin and comparable safety to pravastatin. Atheroscler. Suppl. 10(2), P770 (2009).
    • (2009) Atheroscler. Suppl. , vol.10 , Issue.2
    • Stender, S.1    Hounslow, N.2
  • 50
    • 73249115558 scopus 로고    scopus 로고
    • Effects of pitavastatin (LIVALO Tablet) on high density lipoprotein cholesterol (HDL-C) in hypercholesterolemia
    • Teramoto T, Shimano H, Yokote K, Urashima M: Effects of pitavastatin (LIVALO Tablet) on high density lipoprotein cholesterol (HDL-C) in hypercholesterolemia. J. Atheroscler. Thromb. 16, 654-661 (2009).
    • (2009) J. Atheroscler. Thromb. , vol.16 , pp. 654-661
    • Teramoto, T.1    Shimano, H.2    Yokote, K.3    Urashima, M.4
  • 52
    • 56649111325 scopus 로고    scopus 로고
    • Multicenter collaborative randomized parallel group comparative study of pitavastatin and atorvastatin in Japanese hypercholesterolemic patients: Collaborative study on hypercholesterolemia drug intervention and their benefits for atherosclerosis prevention (CHIBA study)
    • Yokote K, Bujo H, Hanaoka H et al.: Multicenter collaborative randomized parallel group comparative study of pitavastatin and atorvastatin in Japanese hypercholesterolemic patients: collaborative study on hypercholesterolemia drug intervention and their benefits for atherosclerosis prevention (CHIBA study). Atherosclerosis 201, 345-352 (2008).
    • (2008) Atherosclerosis , vol.201 , pp. 345-352
    • Yokote, K.1    Bujo, H.2    Hanaoka, H.3
  • 53
    • 47149104736 scopus 로고    scopus 로고
    • A 52-week, randomized, open-label, parallel-group comparison of the tolerability and effects of pitavastatin and atorvastatin on high-density lipoprotein cholesterol levels and glucose metabolism in Japanese patients with elevated levels of low-density lipoprotein cholesterol and glucose intolerance
    • Sasaki J, Ikeda Y, Kuribayashi T et al.: A 52-week, randomized, open-label, parallel-group comparison of the tolerability and effects of pitavastatin and atorvastatin on high-density lipoprotein cholesterol levels and glucose metabolism in Japanese patients with elevated levels of low-density lipoprotein cholesterol and glucose intolerance. Clin. Ther. 30(6), 1089-1101 (2008).
    • (2008) Clin. Ther. , vol.30 , Issue.6 , pp. 1089-1101
    • Sasaki, J.1    Ikeda, Y.2    Kuribayashi, T.3
  • 54
    • 0036804616 scopus 로고    scopus 로고
    • Effect of morning versus evening intake of simvastatin on the serum cholesterol level in patients with coronary heart disease
    • Lund TM, Torsvik H, Falch D, Christophersen B, Skardal R, Gullestad L: Effect of morning versus evening intake of simvastatin on the serum cholesterol level in patients with coronary heart disease. Am. J. Cardiol. 90, 784-786 (2002).
    • (2002) Am. J. Cardiol. , vol.90 , pp. 784-786
    • Lund, T.M.1    Torsvik, H.2    Falch, D.3    Christophersen, B.4    Skardal, R.5    Gullestad, L.6
  • 55
    • 0141528534 scopus 로고    scopus 로고
    • Taking simvastatin in the morning compared with in the evening: Randomised controlled trial
    • Wallace A, Chinn D, Rubin G: Taking simvastatin in the morning compared with in the evening: randomised controlled trial. BMJ 327, 788 (2003).
    • (2003) BMJ , vol.327 , pp. 788
    • Wallace, A.1    Chinn, D.2    Rubin, G.3
  • 56
    • 71949119028 scopus 로고    scopus 로고
    • Hepatic OATP1B transporters and nuclear receptors PXR and CAR: Interplay, regulation of drug disposition genes, and single nucleotide polymorphisms
    • Meyer Zu Schwabedissen HE, Kim RB: Hepatic OATP1B transporters and nuclear receptors PXR and CAR: interplay, regulation of drug disposition genes, and single nucleotide polymorphisms. Mol. Pharm. 6, 1644-1661 (2009).
    • (2009) Mol. Pharm. , vol.6 , pp. 1644-1661
    • Meyer Zu Schwabedissen, H.E.1    Kim, R.B.2
  • 58
    • 49949104757 scopus 로고    scopus 로고
    • SLCO1B1 variants and statin-induced myopathy-a genome wide study
    • SEARCH Collaborative Group
    • Link E, Parish S, Armitage A et al.; SEARCH Collaborative Group: SLCO1B1 variants and statin-induced myopathy-a genome wide study. N. Engl. J. Med. 359, 789-799 (2008).
    • (2008) N. Engl. J. Med. , vol.359 , pp. 789-799
    • Link, E.1    Parish, S.2    Armitage, A.3
  • 60
    • 2942705774 scopus 로고    scopus 로고
    • Safety of statins: Focus on clinical pharmacokinetics and drug interactions
    • Bellosta S, Paoletti R, Corsini A: Safety of statins: focus on clinical pharmacokinetics and drug interactions. Circulation 109(23 Suppl. 1), III50-III57 (2004).
    • (2004) Circulation , vol.109 , Issue.23 SUPPL. 1
    • Bellosta, S.1    Paoletti, R.2    Corsini, A.3
  • 62
    • 84863697911 scopus 로고    scopus 로고
    • Accessed 10 December 2009
    • WHO Cardiovascular diseases www.who.int/mediacentre/factsheets/fs317/ en/index.html (Accessed 10 December 2009).
    • WHO Cardiovascular Diseases
  • 63
    • 77953868971 scopus 로고    scopus 로고
    • BNF (British National Formulary), 57th Edition. British Medical Association and Royal Pharmaceutical Society of Great Britain, London, UK, (Accessed 30 June 2009)
    • BNF (British National Formulary), 57th Edition. British Medical Association and Royal Pharmaceutical Society of Great Britain, London, UK, 2009. www.bnf.org.uk/bnf/bnf/current/33422.htm (Accessed 30 June 2009).
    • (2009)


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.