Erythropoietin activates mitochondrial biogenesis and couples red cell mass to mitochondrial mass in the heart

Circulation Research

Volumn 106, Issue 11, 2010, Pages 1722-1730

  Carraway, Martha S ^a,b   Suliman, Hagir B ^a   Jones, W Schuyler ^a   Chen, Chien Wen ^a,c   Babiker, Abdelwahid ^a,d   Piantadosi, Claude A ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^c TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^d KING KHALID UNIVERSITY   (Saudi Arabia)

Author keywords

Akt1 protein kinase B; Cardiac metabolism; Erythropoietin; Mitochondrial biogenesis; Nitric oxide

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; ERYTHROPOIETIN RECEPTOR; GREEN FLUORESCENT PROTEIN; HEMOGLOBIN; MITOCHONDRIAL DNA; MITOCHONDRIAL TRANSCRIPTION FACTOR A; NUCLEAR RESPIRATORY FACTOR 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROTEIN KINASE B; RECOMBINANT ERYTHROPOIETIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BREATHING; CONTROLLED STUDY; COPY NUMBER VARIATION; DRUG EFFECT; ENERGY EXPENDITURE; EXERCISE; HEART LEFT VENTRICLE MASS; HEART MITOCHONDRION; HEART MUSCLE CELL; HEMATOCRIT; HEMOGLOBIN BLOOD LEVEL; HYPOXIA; LIGAND BINDING; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; TRANSCRIPTION INITIATION;

ANIMALS; CELL RESPIRATION; CELL SURVIVAL; DNA, MITOCHONDRIAL; DNA-BINDING PROTEINS; ECHOCARDIOGRAPHY; ELECTRON TRANSPORT COMPLEX II; ENERGY METABOLISM; ERYTHROCYTES; ERYTHROPOIETIN, RECOMBINANT; GREEN FLUORESCENT PROTEINS; HEMOGLOBINS; HUMANS; INJECTIONS, SUBCUTANEOUS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MITOCHONDRIA, HEART; MITOCHONDRIAL PROTEINS; MYOCYTES, CARDIAC; NITRIC OXIDE SYNTHASE TYPE III; NUCLEAR RESPIRATORY FACTOR 1; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, ERYTHROPOIETIN; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME FACTORS; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

EID: 77953808996     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.109.214353     Document Type: Article

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