Different effects of surfactant proteins B and C - Implications for development of synthetic surfactants

Neonatology

Volumn 97, Issue 4, 2010, Pages 367-372

  Curstedt, Tore ^a   Johansson, Jan ^b  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

Author keywords

Lung disease; Peptide analogues; Pulmonary surfactant; Respiratory distress syndrome; Surfactant protein B; Surfactant protein C; Synthetic surfactant

Indexed keywords

BERACTANT; CALFACTANT; DIPALMITOYLPHOSPHATIDYLCHOLINE; KL 4 LUNG SURFACTANT; LUNG SURFACTANT; LYSINE DERIVATIVE; NITROGEN; PALMITIC ACID; PALMITOYLOLEOYLPHOSPHATIDYLGLYCEROL; PEPTIDE DERIVATIVE; PHOSPHATIDYLGLYCEROL; PORACTANT; SURFACTANT PROTEIN B; SURFACTANT PROTEIN C; SURFACTANT PROTEIN C 33; TROMETAMOL; UNCLASSIFIED DRUG; RECOMBINANT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; BOLUS INJECTION; CONFERENCE PAPER; CONTROLLED STUDY; DRUG EFFECT; DRUG MIXTURE; LIPID COMPOSITION; LUNG COLLAPSE; LUNG VOLUME; NEWBORN; NONHUMAN; POSITIVE END EXPIRATORY PRESSURE; PREMATURITY; PRIORITY JOURNAL; RABBIT; TIDAL VOLUME; ANIMAL; CHEMISTRY; DISEASE MODEL; EVALUATION STUDY; HUMAN; PATHOLOGY; PHYSIOLOGY; RESPIRATORY DISTRESS SYNDROME, NEWBORN; SYNTHESIS;

ORYCTOLAGUS CUNICULUS;

ANIMALS; DISEASE MODELS, ANIMAL; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; PULMONARY SURFACTANT-ASSOCIATED PROTEIN B; PULMONARY SURFACTANT-ASSOCIATED PROTEIN C; PULMONARY SURFACTANTS; RABBITS; RECOMBINANT PROTEINS; RESPIRATORY DISTRESS SYNDROME, NEWBORN;

EID: 77953785077     PISSN: 16617800     EISSN: 16617819     Source Type: Journal    
DOI: 10.1159/000297767     Document Type: Conference Paper

References (33)

1. Halliday HL: Recent clinical trials of surfactant treatment for neonates. Biol Neonate 2006; 89: 323-329.
2. Kattwinkel J: Synthetic surfactants: the search goes on. Pediatrics 2005; 115: 1075-1076.
3. Berggren P, Curstedt T, Grossmann G, Nilsson R, Robertson B: Physiological activity of pulmonary surfactant with low protein content: effect of enrichment with synthetic phospholipids. Exp Lung Res 1985; 8: 29-51.
4. Johansson J, Curstedt T: Molecular structures and interactions of pulmonary surfactant components. Eur J Biochem 1997; 244: 675-693.
5. Curstedt T, Johansson J: New synthetic surfactants - basic science. Biol Neonate 2005; 87: 332-337.
6. Curstedt T, Johansson J: New synthetic surfactant - how and when? Biol Neonate 2006; 89: 336-339.
7. Hawgood S, Ogawa A, Yukitake K, Schlueter M, Brown C, White T, Buckley D, Lesikar D, Benson B: Lung function in premature rabbits treated with recombinant human surfactant protein-C. Am J Respir Crit Care Med 1996; 154: 484-490.
8. Davis AJ, Jobe AH, Häfner D, Ikegami M: Lung function in premature lambs and rabbits treated with a recombinant SP-C surfactant. Am J Respir Crit Care Med 1998; 157: 553-559.
9. Nilsson G, Gustafsson M, Vandenbussche G, Veldhuizen E, Griffiths WJ, Sjövall J, Haagsman HP, Ruysschaert JM, Robertson B, Curstedt T, Johansson J: Synthetic peptidecontaining surfactants. Evaluation of transmembrane versus amphipathic helices and surfactant protein C poly-valyl to poly-leucyl substitution. Eur J Biochem 1998; 255: 116-124.
10. Johansson J, Some M, Linderholm BM, Almlén A, Curstedt T, Robertson B: A synthetic surfactant based on a poly-Leu SP-C analog and phospholipids: effects on tidal volumes and lung gas volumes in ventilated immature newborn rabbits. J Appl Physiol 2003; 95: 2055-2063.
11. Revak SD, Merritt TA, Cochrane CG, Heldt GP, Alberts MS, Anderson DW, Kheiter A: Efficacy of synthetic peptide-containing surfactant in the treatment of respiratory distress syndrome in preterm infant rhesus monkeys. Pediatr Res 1996; 39: 715-724.
12. Gastiasoro-Cuesta E, Alvarez-Diaz FJ, Rey- Santano C, Arnaiz-Renedo A, Loureiro- Gonzalez B, Valls-i-Soler A: Acute and sustained effects of lucinactant versus poractant- α on pulmonary gas exchange and mechanics in premature lambs with respiratory distress syndrome. Pediatrics 2006; 117: 295-303.
13. Michna J, Jobe AH, Ikegami M: Positive endexpiratory pressure preserves surfactant function in preterm lambs. Am J Respir Crit Care Med 1999; 160: 634-639.
14. Merritt TA, Kheiter A, Cochrane CG: Positive end-expiratory pressure during KL 4 surfactant instillation enhances intrapulmonary distribution in a simian model of respiratory distress syndrome. Pediatr Res 1995; 38: 211-217.
15. Waring AJ, Walther FJ, Gordon LM, Hernandez- Juviel JM, Hong T, Sherman MA, Alonso C, Alig T, Braun A, Bacon D, Zasadzinski JA: The role of charged amphipathic helices in the structure and function of surfactant protein B. J Peptide Res 2005; 66: 364-374.
16. Balaraman V, Meister J, Ku TL, Sood SL, Tam E, Killeen J, Uyehara CF, Egan E, Easa D: Lavage administration of dilute surfactants after acute lung injury in neonatal piglets. Am J Respir Crit Care Med 1998; 158: 12-17.
17. Walther FJ, Hernández-Juviel JM, Gordon LM, Waring AJ, Stenger P, Zasadzinski JA: Comparison of three lipid formulations for synthetic surfactant with a surfactant protein B analog. Exp Lung Res 2005; 31: 563-579.
18. Spragg RG, Smith RM, Harris K, Lewis J, Häfner D, Germann P: Effect of recombinant SP-C surfactant in a porcine lavage model of acute lung injury. J Appl Physiol 2000; 88: 674-681.
19. Cochrane CG, Revak SD: Pulmonary surfactant protein B (SP-B): structure-function relationships. Science 1991; 254: 566-568.
20. Gustafsson M, Vandenbussche G, Curstedt T, Ruysschaert JM, Johansson J: The 21-residue surfactant peptide (LysLeu 4 ) 4 Lys (KL 4 ) is a transmembrane α -helix with a mixed nonpolar/polar surface. FEBS Lett 1996; 384: 185-188.
21. Moya FR, Gadzinowski J, Bancalari E, Salinas V, Kopelman B, Bancalari A, Kornacka MK, Merritt TA, Segal R, Schaber CJ, Tsai H, Massaro J, d'Agostino R, for the International Surfaxin Collaborative Study Group: A multicenter, randomized, masked, comparison trial of lucinactant, colfosceril palmitate, and beractant for the prevention of respiratory distress syndrome among very preterm infants. Pediatrics 2005; 115: 1018-1029.
22. Almlén A, Stichtenoth G, Robertson B, Johansson J, Curstedt T: Concentration dependence of a poly-leucine surfactant protein C analogue on in vitro and in vivo surfactant activity. Neonatology 2007; 92: 194-200.
23. Almlén A, Stichtenoth G, Linderholm B, Haegerstrand-Björkman M, Robertson B, Johansson J, Curstedt T: Surfactant proteins B and C are both necessary for alveolar stability at end-expiration in premature rabbits with respiratory distress syndrome. J Appl Physiol 2008; 104: 1101-1108.
24. Almlén A, Walther FJ, Waring AJ, Robertson B, Johansson J, Curstedt T: Synthetic surfactant based on analogues of SP-B and SP-C is superior to single-peptide surfactants in ventilated premature rabbits. Neonatology 2010; 98: 91-99.
25. Scherle W: A simple method for volumetry of organs in quantitative stereology. Mikroskopie 1970; 26: 57-60.
26. Enhorning G, Shennan A, Possmayer F, Dunn M, Chen CP, Milligan J: Prevention of neonatal respiratory distress syndrome by tracheal instillation of surfactant: a randomized clinical trial. Pediatrics 1985; 76: 145-153.
27. Curstedt T, Johansson J, Robertson B, Persson P, Löwenadler B, Jörnvall H: Structure and function of hydrophobic surfactant-associated proteins; in Bevilaqua G, Parmigiani S, Robertson B (eds): Surfactant in Clinical Practice. Chur, Harwood, 1993, pp 55-60.
28. Gortner L, Pohlandt F, Disse B, Weller E: Effects of bovine surfactant in premature lambs after intratracheal application. Eur J Pediatr 1990; 149: 280-283.
29. Bernhard W, Mottaghian J, Gebert A, Rau GA, Von Der Hardt, H, Poets CF: Commercial versus native surfactants. Am J Respir Crit Care Med 2000; 162: 1524-1533.
30. Notter RH, Wang Z, Egan EA, Holm BA: Component-specific surface and physiological activity in bovine-derived lung surfactants. Chem Phys Lipids 2002; 114: 21-34.
31. Rüdiger M, Tölle A, Meier W, Rüstow B: Naturally derived commercial surfactants differ in composition of surfactant lipids and in surface viscosity. Am J Physiol 2005; 288: L379-L383.
32. Ramanathan R: Animal-derived surfactants: where are we? The evidence from randomized, controlled clinical trials. J Perinatol 2009; 29(suppl 2):S38-S43.
33. Ramanathan R: Choosing a right surfactant for respiratory distress syndrome treatment. Neonatology 2009; 95: 1-5.