Influence of CYP3A5 and MDR1 Genetic Polymorphisms on Urinary 6β-Hydroxycortisol/ Cortisol Ratio after Grapefruit Juice Intake in Healthy Chinese

Journal of Clinical Pharmacology

Volumn 50, Issue 7, 2010, Pages 775-784

  Li, Dan ^a   Abudula, Aziguli ^b   Abulahake, Muhutar ^b   Zhu, An Ping ^c   Lou, Ya Qing ^a   Zhang, Guo Liang ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b MINZU UNIVERSITY OF CHINA   (China)

^c Department of Outpatient Clinic   (China)

Author keywords

Chinese; CYP3A activity; Genetic polymorphism; Grapefruit juice; MDR1

Indexed keywords

6BETA HYDROXYHYDROCORTISONE; CYTOCHROME P450 3A5; HYDROCORTISONE; MULTIDRUG RESISTANCE PROTEIN 1;

ADULT; ARTICLE; CHINESE; FEMALE; FOOD INTAKE; GENETIC POLYMORPHISM; GENOTYPE; GRAPEFRUIT JUICE; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; PHENOTYPE; URINALYSIS;

ADULT; BEVERAGES; CHINA; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CITRUS PARADISI; CYTOCHROME P-450 CYP3A; DNA; ETHNIC GROUPS; FEMALE; FOOD-DRUG INTERACTIONS; GENOTYPE; HUMANS; HYDROCORTISONE; MALE; P-GLYCOPROTEIN; PHENOTYPE; POLYMORPHISM, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; YOUNG ADULT;

EID: 77953780100     PISSN: 00912700     EISSN: 15524604     Source Type: Journal    
DOI: 10.1177/0091270009354997     Document Type: Article

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