-
1
-
-
68849092509
-
Impact of regulatory polymorphisms in organic anion transporter genes in the human liver
-
Aoki M, Terada T, Ogasawara K, Katsura T, Hatano E, Ikai I, and Inui K (2009) Impact of regulatory polymorphisms in organic anion transporter genes in the human liver. Pharmacogenet Genomics 19:647-656.
-
(2009)
Pharmacogenet Genomics
, vol.19
, pp. 647-656
-
-
Aoki, M.1
Terada, T.2
Ogasawara, K.3
Katsura, T.4
Hatano, E.5
Ikai, I.6
Inui, K.7
-
2
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254.
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
3
-
-
0026712825
-
Gadoliniumethoxybenzyl-DTPA, a new liver-specific magnetic resonance contrast agent. Kinetic and enhancement patterns in normal and cholestatic rats
-
Clément O, Mühler A, Vexler V, Berthezène Y, and Brasch RC (1992) Gadoliniumethoxybenzyl-DTPA, a new liver-specific magnetic resonance contrast agent. Kinetic and enhancement patterns in normal and cholestatic rats. Invest Radiol 27:612-619.
-
(1992)
Invest Radiol
, vol.27
, pp. 612-619
-
-
Clément, O.1
Mühler, A.2
Vexler, V.3
Berthezène, Y.4
Brasch, R.C.5
-
4
-
-
0035971239
-
Hepatic uptake of bilirubin and its conjugates by the human organic anion transporter SLC21A6
-
Cui Y, Konig J, Leier I, Buchholz U, and Keppler D (2001) Hepatic uptake of bilirubin and its conjugates by the human organic anion transporter SLC21A6. J Biol Chem 276:9626-9630.
-
(2001)
J Biol Chem
, vol.276
, pp. 9626-9630
-
-
Cui, Y.1
Konig, J.2
Leier, I.3
Buchholz, U.4
Keppler, D.5
-
5
-
-
33845524038
-
Organic anion transporting polypeptide 2B1 is a high-affinity transporter for atorvastatin and is expressed in the human heart
-
Grube M, Köck K, Oswald S, Draber K, Meissner K, Eckel L, Böhm M, Felix SB, Vogelgesang S, Jedlitschky G, et al. (2006) Organic anion transporting polypeptide 2B1 is a high-affinity transporter for atorvastatin and is expressed in the human heart. Clin Pharmacol Ther 80:607-620.
-
(2006)
Clin Pharmacol Ther
, vol.80
, pp. 607-620
-
-
Grube, M.1
Köck, K.2
Oswald, S.3
Draber, K.4
Meissner, K.5
Eckel, L.6
Böhm, M.7
Felix, S.B.8
Vogelgesang, S.9
Jedlitschky, G.10
-
6
-
-
0028231206
-
Molecular cloning, chromosomal localization, and functional characterization of a human liver Na+/bile acid cotransporter
-
Hagenbuch B and Meier PJ (1994) Molecular cloning, chromosomal localization, and functional characterization of a human liver Na+/bile acid cotransporter. J Clin Invest 93:1326-1331. (Pubitemid 24087193)
-
(1994)
Journal of Clinical Investigation
, vol.93
, Issue.3
, pp. 1326-1331
-
-
Hagenbuch, B.1
Meier, P.J.2
-
7
-
-
0035036756
-
Multidrug resistance P-glycoprotein 2 is essential for the biliary excretion of indocyanine green
-
Huang L and Vore M (2001) Multidrug resistance p-glycoprotein 2 is essential for the biliary excretion of indocyanine green. Drug Metab Dispos 29:634-637. (Pubitemid 32374562)
-
(2001)
Drug Metabolism and Disposition
, vol.29
, Issue.5
, pp. 634-637
-
-
Vore, M.1
-
8
-
-
0036895706
-
Gadoliniumethoxybenzyl-diethylenetriamine-pentaacetic acid interaction with clinical drugs in rats
-
Kato N, Yokawa T, Tamura A, Heshiki A, Ebert W, and Weinmann HJ (2002) Gadoliniumethoxybenzyl-diethylenetriamine-pentaacetic acid interaction with clinical drugs in rats. Invest Radiol 37:680-684.
-
(2002)
Invest Radiol
, vol.37
, pp. 680-684
-
-
Kato, N.1
Yokawa, T.2
Tamura, A.3
Heshiki, A.4
Ebert, W.5
Weinmann, H.J.6
-
9
-
-
0242469240
-
Organic anion-transporting polypeptide (OATP) transporter family and drug disposition
-
Kim RB (2003) Organic anion-transporting polypeptide (OATP) transporter family and drug disposition. Eur J Clin Invest 33 (Suppl 2):1-5.
-
(2003)
Eur J Clin Invest
, vol.33
, Issue.SUPPL. 2
, pp. 1-5
-
-
Kim, R.B.1
-
10
-
-
0032732615
-
Modulation by drugs of human hepatic sodium-dependent bile acid transporter (sodium taurocholate cotransporting polypeptide) activity
-
Kim RB, Leake B, Cvetkovic M, Roden MM, Nadeau J, Walubo A, and Wilkinson GR (1999) Modulation by drugs of human hepatic sodium-dependent bile acid transporter (sodium taurocholate cotransporting polypeptide) activity. J Pharmacol Exp Ther 291:1204-1209.
-
(1999)
J Pharmacol Exp Ther
, vol.291
, pp. 1204-1209
-
-
Kim, R.B.1
Leake, B.2
Cvetkovic, M.3
Roden, M.M.4
Nadeau, J.5
Walubo, A.6
Wilkinson, G.R.7
-
12
-
-
0034725617
-
Localization and genomic organization of a new hepatocellular organic anion transporting polypeptide
-
König J, Cui Y, Nies AT, and Keppler D (2000b) Localization and genomic organization of a new hepatocellular organic anion transporting polypeptide. J Biol Chem 275:23161-23168.
-
(2000)
J Biol Chem
, vol.275
, pp. 23161-23168
-
-
König, J.1
Cui, Y.2
Nies, A.T.3
Keppler, D.4
-
14
-
-
25144494314
-
Human hepatobiliary transport of organic anions analyzed by quadruple-transfected cells
-
Kopplow K, Letschert K, König J, Walter B, and Keppler D (2005) Human hepatobiliary transport of organic anions analyzed by quadruple- transfected cells. Mol Pharmacol 68:1031-1038.
-
(2005)
Mol Pharmacol
, vol.68
, pp. 1031-1038
-
-
Kopplow, K.1
Letschert, K.2
König, J.3
Walter, B.4
Keppler, D.5
-
15
-
-
0030838171
-
Chlorambucil-taurocholate is transported by bile acid carriers expressed in human hepatocellular carcinomas
-
Kullak-Ublick GA, Glasa J, Böker C, Oswald M, Grützner U, Hagenbuch B, Stieger B, Meier PJ, Beuers U, Kramer W, et al. (1997) Chlorambucil-taurocholate is transported by bile acid carriers expressed in human hepatocellular carcinomas. Gastroenterology 113:1295-1305.
-
(1997)
Gastroenterology
, vol.113
, pp. 1295-1305
-
-
Kullak-Ublick, G.A.1
Glasa, J.2
Böker, C.3
Oswald, M.4
Grützner, U.5
Hagenbuch, B.6
Stieger, B.7
Meier, P.J.8
Beuers, U.9
Kramer, W.10
-
16
-
-
0035125407
-
Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver
-
Kullak-Ublick GA, Ismair MG, Stieger B, Landmann L, Huber R, Pizzagalli F, Fattinger K, Meier PJ, and Hagenbuch B (2001) Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver. Gastroenterology 120:525-533.
-
(2001)
Gastroenterology
, vol.120
, pp. 525-533
-
-
Kullak-Ublick, G.A.1
Ismair, M.G.2
Stieger, B.3
Landmann, L.4
Huber, R.5
Pizzagalli, F.6
Fattinger, K.7
Meier, P.J.8
Hagenbuch, B.9
-
17
-
-
34248562942
-
Differential inhibition of rat and human Na+-dependent taurocholate cotransporting polypeptide (NTCP/SLC10A1) by bosentan: A mechanism for species differences in hepatotoxicity
-
Leslie EM, Watkins PB, Kim RB, and Brouwer KL (2007) Differential inhibition of rat and human Na+-dependent taurocholate cotransporting polypeptide (NTCP/SLC10A1) by bosentan: a mechanism for species differences in hepatotoxicity. J Pharmacol Exp Ther 321:1170-1178.
-
(2007)
J Pharmacol Exp Ther
, vol.321
, pp. 1170-1178
-
-
Leslie, E.M.1
Watkins, P.B.2
Kim, R.B.3
Brouwer, K.L.4
-
18
-
-
0030725999
-
Substrate specificity of sinusoidal bile acid and organic anion uptake systems in rat and human liver
-
Meier PJ, Eckhardt U, Schroeder A, Hagenbuch B, and Stieger B (1997) Substrate specificity of sinusoidal bile acid and organic anion uptake systems in rat and human liver. Hepatology 26:1667-1677. (Pubitemid 27520039)
-
(1997)
Hepatology
, vol.26
, Issue.6
, pp. 1667-1677
-
-
Meier, P.J.1
Eckhardt, U.2
Schroeder, A.3
Hagenbuch, B.4
Stieger, B.5
-
19
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
-
Mosmann T (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65:55-63.
-
(1983)
J Immunol Methods
, vol.65
, pp. 55-63
-
-
Mosmann, T.1
-
20
-
-
70350456265
-
Liver parenchymal enhancement of hepatocyte-phase images in Gd-EOB-DTPA-enhanced MR imaging: Which biological markers of the liver function affect the enhancement?
-
Motosugi U, Ichikawa T, Sou H, Sano K, Tominaga L, Kitamura T, and Araki T (2009) Liver parenchymal enhancement of hepatocyte-phase images in Gd-EOB-DTPA-enhanced MR imaging: which biological markers of the liver function affect the enhancement? J Magn Reson Imaging 30:1042-1046.
-
(2009)
J Magn Reson Imaging
, vol.30
, pp. 1042-1046
-
-
Motosugi, U.1
Ichikawa, T.2
Sou, H.3
Sano, K.4
Tominaga, L.5
Kitamura, T.6
Araki, T.7
-
21
-
-
0026729113
-
Hepatobiliary enhancement with Gd-EOB-DTPA: Comparison of spin-echo and STIR imaging for detection of experimental liver metastases
-
Mühler A, Clément O, Vexler V, Berthezène Y, Rosenau W, and Brasch RC (1992) Hepatobiliary enhancement with Gd-EOB-DTPA: comparison of spin-echo and STIR imaging for detection of experimental liver metastases. Radiology 184:207-213.
-
(1992)
Radiology
, vol.184
, pp. 207-213
-
-
Mühler, A.1
Clément, O.2
Vexler, V.3
Berthezène, Y.4
Rosenau, W.5
Brasch, R.C.6
-
22
-
-
0006419795
-
Complete elimination of the hepatobiliary mr contrast agent Gd-EOB-DTPA in hepatic dysfunction: An experimental study using transport-deficient, mutant rats
-
Muhler A, Oude Elferink RPJ, and Weinmann HJ (1993) Complete elimination of the hepatobiliary mr contrast agent Gd-EOB-DTPA in hepatic dysfunction: an experimental study using transport-deficient, mutant rats. Magnetic Resonance Materials in Physics, Biology and Medicine 1:134-139.
-
(1993)
Magnetic Resonance Materials in Physics, Biology and Medicine
, vol.1
, pp. 134-139
-
-
Muhler, A.1
Oude Elferink, R.P.J.2
Weinmann, H.J.3
-
23
-
-
68149084824
-
Expression of OATP1B3 determines uptake of Gd-EOB-DTPA in hepatocellular carcinoma
-
Narita M, Hatano E, Arizono S, Miyagawa-Hayashino A, Isoda H, Kitamura K, Taura K, Yasuchika K, Nitta T, Ikai I, et al. (2009) Expression of OATP1B3 determines uptake of Gd-EOB-DTPA in hepatocellular carcinoma. J Gastroenterol 44:793-798.
-
(2009)
J Gastroenterol
, vol.44
, pp. 793-798
-
-
Narita, M.1
Hatano, E.2
Arizono, S.3
Miyagawa-Hayashino, A.4
Isoda, H.5
Kitamura, K.6
Taura, K.7
Yasuchika, K.8
Nitta, T.9
Ikai, I.10
-
24
-
-
0030761508
-
Pharmacokinetics of the liver-specific contrast agent Gd-EOB-DTPA in relation to contrast-enhanced liver imaging in humans
-
Schuhmann-Giampieri G, Mahler M, Röll G, Maibauer R, and Schmitz S (1997) Pharmacokinetics of the liver-specific contrast agent Gd-EOB-DTPA in relation to contrast-enhanced liver imaging in humans. J Clin Pharmacol 37:587-596. (Pubitemid 27443539)
-
(1997)
Journal of Clinical Pharmacology
, vol.37
, Issue.7
, pp. 587-596
-
-
Schuhmann-Giampieri, G.1
Mahler, M.2
Roll, G.3
Maibauer, R.4
Schmitz, S.5
-
25
-
-
0027358478
-
Biliary excretion and pharmacokinetics of a gadolinium chelate used as a liver-specific contrast agent for magnetic resonance imaging in the rat
-
DOI 10.1002/jps.2600820809
-
Schuhmann-Giampieri G, Schmitt-Willich H, Frenzel T, and Schitt-Willich H [corrected to Schmitt-Willich H] (1993) Biliary excretion and pharmacokinetics of a gadolinium chelate used as a liver-specific contrast agent for magnetic resonance imaging in the rat. J Pharm Sci 82:799-803. (Pubitemid 23314085)
-
(1993)
Journal of Pharmaceutical Sciences
, vol.82
, Issue.8
, pp. 799-803
-
-
Schuhmann-Giampieri, G.1
Schitt-Willich, H.2
Frenzel, T.3
-
26
-
-
0026533551
-
Preclinical evaluation of Gd-EOB-DTPA as a contrast agent in MR imaging of the hepatobiliary system
-
Schuhmann-Giampieri G, Schmitt-Willich H, Press WR, Negishi C, Weinmann HJ, and Speck U (1992) Preclinical evaluation of Gd-EOB-DTPA as a contrast agent in MR imaging of the hepatobiliary system. Radiology 183:59-64.
-
(1992)
Radiology
, vol.183
, pp. 59-64
-
-
Schuhmann-Giampieri, G.1
Schmitt-Willich, H.2
Press, W.R.3
Negishi, C.4
Weinmann, H.J.5
Speck, U.6
-
27
-
-
34247390725
-
The influence of macrolide antibiotics on the uptake of organic anions and drugs mediated by OATP1B1 and OATP1B3
-
Seithel A, Eberl S, Singer K, Auge D, Heinkele G, Wolf NB, Dörje F, Fromm MF, and König J (2007) The influence of macrolide antibiotics on the uptake of organic anions and drugs mediated by OATP1B1 and OATP1B3. Drug Metab Dispos 35:779-786.
-
(2007)
Drug Metab Dispos
, vol.35
, pp. 779-786
-
-
Seithel, A.1
Eberl, S.2
Singer, K.3
Auge, D.4
Heinkele, G.5
Wolf, N.B.6
Dörje, F.7
Fromm, M.F.8
König, J.9
-
28
-
-
79952454128
-
MR imaging of the biliary tract with Gd-EOB-DTPA: Effect of liver function on signal intensity
-
doi: 10.1016/j.ejrad.2009.08.008
-
Takao H, Akai H, Tajima T, Kiryu S, Watanabe Y, Imamura H, Akahane M, Yoshioka N, Kokudo N, and Ohtomo K (2009) MR imaging of the biliary tract with Gd-EOB-DTPA: Effect of liver function on signal intensity. Eur J Radiol doi: 10.1016/j.ejrad.2009.08.008.
-
(2009)
Eur J Radiol
-
-
Takao, H.1
Akai, H.2
Tajima, T.3
Kiryu, S.4
Watanabe, Y.5
Imamura, H.6
Akahane, M.7
Yoshioka, N.8
Kokudo, N.9
Ohtomo, K.10
-
29
-
-
0033045409
-
Hepatic uptake of the magnetic resonance imaging contrast agent gadoxetate by the organic anion transporting polypeptide Oatp1
-
van Montfoort JE, Stieger B, Meijer DK, Weinmann HJ, Meier PJ, and Fattinger KE (1999) Hepatic uptake of the magnetic resonance imaging contrast agent gadoxetate by the organic anion transporting polypeptide Oatp1. J Pharmacol Exp Ther 290:153-157. (Pubitemid 29302315)
-
(1999)
Journal of Pharmacology and Experimental Therapeutics
, vol.290
, Issue.1
, pp. 153-157
-
-
Van Montfoort, J.E.1
Stieger, B.2
Meijer, D.K.F.3
Weinmann, H.-J.4
Meier, P.J.5
Fattinger, K.E.6
-
30
-
-
0036293982
-
Interactions of rifamycin SV and rifampicin with organic anion uptake systems of human liver
-
Vavricka SR, Van Montfoort J, Ha HR, Meier PJ, and Fattinger K (2002) Interactions of rifamycin SV and rifampicin with organic anion uptake systems of human liver. Hepatology 36:164-172.
-
(2002)
Hepatology
, vol.36
, pp. 164-172
-
-
Vavricka, S.R.1
Van Montfoort, J.2
Ha, H.R.3
Meier, P.J.4
Fattinger, K.5
|