Visualization of embryonic lymphangiogenesis advances the use of the zebrafish model for research in cancer and lymphatic pathologies

Developmental Dynamics

Volumn 239, Issue 7, 2010, Pages 2128-2135

  Flores, Maria Vega ^a   Hall, Christopher J ^a   Crosier, Kathryn E ^a   Crosier, Philip S ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Drug discovery; Lymphangiogenesis; Lyve1; Rapamycin; Zebrafish

Indexed keywords

HOMEODOMAIN PROTEIN; PROTEIN LYVE1; PROTEIN PROX1; PROTEIN VEGFC; RAPAMYCIN; UNCLASSIFIED DRUG; VESICULAR TRANSPORT PROTEIN; ZEBRAFISH PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER RESEARCH; CONTROLLED STUDY; EMBRYO DEVELOPMENT; LYMPHANGIOGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEPLETION; PROTEIN EXPRESSION; ZEBRA FISH; ANIMAL; DRUG EFFECTS; EMBRYOLOGY; GENETICS; IN SITU HYBRIDIZATION; METABOLISM; MOUSE; NEOPLASM; PATHOLOGY; PHYSIOLOGY;

DANIO RERIO; MAMMALIA;

ANIMALS; IN SITU HYBRIDIZATION; LYMPHANGIOGENESIS; MICE; NEOPLASMS; SIROLIMUS; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 77953749881     PISSN: 10588388     EISSN: 10970177     Source Type: Journal    
DOI: 10.1002/dvdy.22328     Document Type: Article

References (34)

1. Ambrose CT. 2006. Immunology's first priority dispute - an account of the 17th-century Rudbeck-Bartholin feud. Cell Immunol 242:1-8.
2. Baldwin ME, Halford MM, Roufail S, Williams RA, Hibbs ML, Grail D, Kubo H, Stacker SA, Achen MG. 2005. Vascular endothelial growth factor D is dispensable for development of the lymphatic system. Mol Cell Biol 25:2441-2449.
3. Butler MG, Isogai S, Weinstein BM. 2009. Lymphatic development. Birth Defects Res C Embryo Today 87:222-231.
4. Cha YR, Weinstein BM. 2007. Visualization and experimental analysis of blood vessel formation using transgenic zebrafish. Birth Defects Res C Embryo Today 81:286-296.
5. Cueni LN, Detmar M. 2008. The lymphatic system in health and disease. Lymphat Res Biol 6:109-122.
6. Flores MV, Lam EY, Crosier P, Crosier K. 2006. A hierarchy of Runx transcription factors modulate the onset of chondrogenesis in craniofacial endochondral bones in zebrafish. Dev Dyn 235:3166-3176.
7. Hogan BM, Bos FL, Bussmann J, Witte M, Chi NC, Duckers HJ, Schulte-Merker S. 2009. Ccbe1 is required for embryonic lymphangiogenesis and venous sprouting. Nat Genet 41:396-398.
8. Huber S, Bruns CJ, Schmid G, Hermann PC, Conrad C, Niess H, Huss R, Graeb C, Jauch KW, Heeschen C, Guba M. 2007. Inhibition of the mammalian target of rapamycin impedes lymphangiogenesis. Kidney Int 71:771-777.
9. Isogai S, Hitomi J, Yaniv K, Weinstein BM. 2009. Zebrafish as a new animal model to study lymphangiogenesis. Anat Sci Int 84:102-111.
10. Jowett T, Yan YL. 1996. Double fluorescent in situ hybridization to zebrafish embryos. Trends Genet 12:387-389.
11. Karkkainen MJ, Haiko P, Sainio K, Partanen J, Taipale J, Petrova TV, Jeltsch M, Jackson DG, Talikka M, Rauvala H, Betsholtz C, Alitalo K. 2004. Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins. Nat Immunol 5:74-80.
12. Karpanen T, Alitalo K. 2008. Molecular biology and pathology of lymphangiogenesis. Annu Rev Pathol 3:367-397.
13. Kimmel CB, Ballard WW, Kimmel SR, Ullmann B, Schilling TF. 1995. Stages of embryonic development of the zebrafish. Dev Dyn 203:253-310.
14. Kobayashi S, Kishimoto T, Kamata S, Otsuka M, Miyazaki M, Ishikura H. 2007. Rapamycin, a specific inhibitor of the mammalian target of rapamycin, suppresses lymphangiogenesis and lymphatic metastasis. Cancer Sci 98:726-733. (Pubitemid 46563450)
15. Kuchler AM, Gjini E, Peterson-Maduro J, Cancilla B, Wolburg H, Schulte-Merker S. 2006. Development of the zebrafish lymphatic system requires VEGFC signaling. Curr Biol 16:1244-1248. (Pubitemid 43867297)
16. Larson JD, Wadman SA, Chen E, Kerley L, Clark KJ, Eide M, Lippert S, Nasevicius A, Ekker SC, Hackett PB, Essner JJ. 2004. Expression of VE-cadherin in zebrafish embryos: a new tool to evaluate vascular development. Dev Dyn 231:204-213. (Pubitemid 39095211)
17. Lee SJ, Chan TH, Chen TC, Liao BK, Hwang PP, Lee H. 2008. LPA1 is essential for lymphatic vessel development in zebrafish. FASEB J 22:3706-3715.
18. Makky K, Tekiela J, Mayer AN. 2007. Target of rapamycin (TOR) signaling controls epithelial morphogenesis in the vertebrate intestine. Dev Biol 303: 501-513.
19. Molina G, Vogt A, Bakan A, Dai W, Queiroz de Oliveira P, Znosko W, Smithgall TE, Bahar I, Lazo JS, Day BW, Tsang M. 2009. Zebrafish chemical screening reveals an inhibitor of Dusp6 that expands cardiac cell lineages. Nat Chem Biol 5:680-687.
20. Monteiro R, van Dinther M, Bakkers J, Wilkinson R, Patient R, ten Dijke P, Mummery C. 2008. Two novel type II receptors mediate BMP signalling and are required to establish left-right asymmetry in zebrafish. Dev Biol 315:55-71.
21. Mumprecht V, Detmar M. 2009. Lymphangiogenesis and cancer metastasis. J Cell Mol Med 13:1405-1416.
22. Nasevicius A, Ekker SC. 2000. Effective targeted gene 'knockdown' in zebrafish. Nat Genet 26:216-220.
23. North TE, Goessling W, Walkley CR, Lengerke C, Kopani KR, Lord AM, Weber GJ, Bowman TV, Jang IH, Grosser T, Fitzgerald GA, Daley GQ, Orkin SH, Zon LI. 2007. Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis. Nature 447:1007-1011.
24. North TE, Goessling W, Peeters M, Li P, Ceol C, Lord AM, Weber GJ, Harris J, Cutting CC, Huang P, Dzierzak E, Zon LI. 2009. Hematopoietic stem cell development is dependent on blood flow. Cell 137:736-748.
25. Ny A, Koch M, Schneider M, Neven E, Tong RT, Maity S, Fischer C, Plaisance S, Lambrechts D, Heligon C, Terclavers S, Ciesiolka M, Kalin R, Man WY, Senn I, Wyns S, Lupu F, Brandli A, Vleminckx K, Collen D, Dewerchin M, Conway EM, Moons L, Jain RK, Carmeliet P. 2005. A genetic Xenopus laevis tadpole model to study lymphangiogenesis. Nat Med 11:998-1004.
26. Perrino MA, Yelick PC. 2004. Immunolocalization of Alk8 during replacement tooth development in zebrafish. Cells Tissues Organs 176:17-27.
27. Raya A, Belmonte JC. 2006. Left-right asymmetry in the vertebrate embryo: from early information to higher-level integration. Nat Rev Genet 7:283-293.
28. Sabin FR. 1902. On the origin of the lymphatic system from the veins and the development of the lymph hearts and thoracic duct in the pig. Am J Anat 1:367-391.
29. Srinivasan RS, Dillard ME, Lagutin OV, Lin FJ, Tsai S, Tsai MJ, Samokhvalov IM, Oliver G. 2007. Lineage tracing demonstrates the venous origin of the mammalian lymphatic vasculature. Genes Dev 21:2422-2432.
30. Stacker SA, Achen MG, Jussila L, Baldwin ME, Alitalo K. 2002. Lymphangiogenesis and cancer metastasis. Nat Rev Cancer 2:573-583.
31. Tammela T, Alitalo K. 2010. Lymphangiogenesis: molecular mechanisms and future promise. Cell 140:460-476.
32. Thompson MA, Ransom DG, Pratt SJ, MacLennan H, Kieran MW, Detrich HW, 3rd, Vail B, Huber TL, Paw B, Brownlie AJ, Oates AC, Fritz A, Gates MA, Amores A, Bahary N, Talbot WS, Her H, Beier DR, Postlethwait JH, Zon LI. 1998. The cloche and spadetail genes differentially affect hematopoiesis and vasculogenesis. Dev Biol 197:248-269.
33. Yaniv K, Isogai S, Castranova D, Dye L, Hitomi J, Weinstein BM. 2006. Live imaging of lymphatic development in the zebrafish. Nat Med 12:711-716.
34. Yeh JR, Munson KM, Elagib KE, Goldfarb AN, Sweetser DA, Peterson RT. 2009. Discovering chemical modifiers of oncogene-regulated hematopoietic differentiation. Nat Chem Biol 5:236-243.