Role of growth factor receptor transactivation in high glucose-induced increased levels of Gq/11α and signaling in vascular smooth muscle cells

Journal of Molecular and Cellular Cardiology

Volumn 49, Issue 2, 2010, Pages 221-233

  Descorbeth, Magda ^a   Anand Srivastava, Madhu B ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

CSrc; Gq protein; Growth factor receptor; High glucose; PI turnover; PLC ; VSMC

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; 4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; 6,7 DIMETHYL 2 PHENYLQUINOXALINE; DACTINOMYCIN; ENDOTHELIN 1; EPIDERMAL GROWTH FACTOR RECEPTOR; GROWTH FACTOR RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; INOSITOL TRISPHOSPHATE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHOLIPASE C BETA1; PHOSPHOLIPASE C BETA2; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN KINASE B; WORTMANNIN;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CELL PROLIFERATION; CONTROLLED STUDY; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; TRANSACTIVATION; VASCULAR SMOOTH MUSCLE;

ANIMALS; AORTA; CELL PROLIFERATION; DACTINOMYCIN; ENDOTHELIN-1; ENZYME ACTIVATION; GLUCOSE; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; INOSITOL 1,4,5-TRISPHOSPHATE; MITOGEN-ACTIVATED PROTEIN KINASES; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PHOSPHOLIPASE C BETA; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; STREPTOZOCIN; TRANSCRIPTIONAL ACTIVATION;

EID: 77953727457     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2009.12.010     Document Type: Article

References (54)

1. Giugliano D., Ceriello A., Paolisso G. Oxidative stress and diabetic vascular complications. Diabetes Care 1996, 19:257-267.
2. Koya D., King G.L. Protein kinase C activation and the development of diabetic complications. Diabetes 1998, 47:859-866.
3. Akiyama N., Naruse K., Kobayashi Y., Nakamura N., Hamada Y., Nakashima E., et al. High glucose-induced upregulation of Rho/Rho-kinase via platelet-derived growth factor receptor-beta increases migration of aortic smooth muscle cells. J. Mol. Cell Cardiol. 2008, 45:326-332.
4. Berridge M.J. Inositol trisphosphate as a second messenger in signal transduction. Ann. N.Y. Acad. Sci. 1987, 494:39-51.
5. Smrcka A.V., Hepler J.R., Brown K.O., Sternweis P.C. Regulation of polyphosphoinositide-specific phospholipase C activity by purified Gq. Science 1991, 251:804-807.
6. Brass L.F., Shaller C.C., Belmonte E.J. Inositol 1,4,5-triphosphate-induced granule secretion in platelets. Evidence that the activation of phospholipase C mediated by platelet thromboxane receptors involves a guanine nucleotide binding protein-dependent mechanism distinct from that of thrombin. J. Clin. Invest. 1987, 79:1269-1275.
7. Shenker A., Goldsmith P., Unson C.G., Spiegel A.M. The G protein coupled to the thromboxane A2 receptor in human platelets is a member of the novel Gq family. J. Biol. Chem. 1991, 266:9309-9313.
8. Goraya T.Y., Wilkins P., Douglas J.G., Zhou J., Berti-Mattera L.N. Signal transduction alterations in peripheral nerves from streptozotocin-induced diabetic rats. J. Neurosci. Res. 1995, 41:518-525.
9. Inoguchi T., Battan R., Handler E., Sportsman J.R., Heath W., King G.L. Preferential elevation of protein kinase C isoform beta II and diacylglycerol levels in the aorta and heart of diabetic rats: differential reversibility to glycemic control by islet cell transplantation. Proc. Natl. Acad. Sci. U. S. A. 1992, 89:11059-11063.
10. Shiba T., Inoguchi T., Sportsman J.R., Heath W.F., Bursell S., King G.L. Correlation of diacylglycerol level and protein kinase C activity in rat retina to retinal circulation. Am. J. Physiol. 1993, 265:E783-E793.
11. Tappia P.S., Asemu G., Aroutiounova N., Dhalla N.S. Defective sarcolemmal phospholipase C signaling in diabetic cardiomyopathy. Mol. Cell Biochem. 2004, 261:193-199.
12. Yang J.M., Cho C.H., Kong K.A., Jang I.S., Kim H.W., Juhnn Y.S. Increased expression of Galphaq protein in the heart of streptozotocin-induced diabetic rats. Exp. Mol. Med. 1999, 31:179-184.
13. Ramana K.V., Friedrich B., Tammali R., West M.B., Bhatnagar A., Srivastava S.K. Requirement of aldose reductase for the hyperglycemic activation of protein kinase C and formation of diacylglycerol in vascular smooth muscle cells. Diabetes 2005, 54:818-829.
14. Williams B., Gallacher B., Patel H., Orme C. Glucose-induced protein kinase C activation regulates vascular permeability factor mRNA expression and peptide production by human vascular smooth muscle cells in vitro. Diabetes 1997, 46:1497-1503.
15. Descorbeth M., Anand-Srivastava M.B. High glucose increases the expression of Gq/11{alpha} and PLC-{beta} proteins and associated signaling in vascular smooth muscle cells. Am. J. Physiol. Heart Circ. Physiol. 2008, 295:H2135-H2142.
16. Campbell M., Allen W.E., Silversides J.A., Trimble E.R. Glucose-induced phosphatidylinositol 3-kinase and mitogen-activated protein kinase-dependent upregulation of the platelet-derived growth factor-beta receptor potentiates vascular smooth muscle cell chemotaxis. Diabetes 2003, 52:519-526.
17. Kawano M., Koshikawa T., Kanzaki T., Morisaki N., Saito Y., Yoshida S. Diabetes mellitus induces accelerated growth of aortic smooth muscle cells: association with overexpression of PDGF beta-receptors. Eur. J. Clin. Invest. 1993, 23:84-90.
18. Nakamura J., Kasuya Y., Hamada Y., Nakashima E., Naruse K., Yasuda Y., et al. Glucose-induced hyperproliferation of cultured rat aortic smooth muscle cells through polyol pathway hyperactivity. Diabetologia 2001, 44:480-487.
19. Yamaguchi H., Igarashi M., Hirata A., Sugae N., Tsuchiya H., Jimbu Y., et al. Altered PDGF-BB-induced p38 MAP kinase activation in diabetic vascular smooth muscle cells: roles of protein kinase C-delta. Arterioscler. Thromb. Vasc. Biol. 2004, 24:2095-2101.
20. Konishi A., Berk B.C. Epidermal growth factor receptor transactivation is regulated by glucose in vascular smooth muscle cells. J. Biol. Chem. 2003, 278:35049-35056.
21. Wu D., Peng F., Zhang B., Ingram A.J., Gao B., Krepinsky J.C. Collagen I induction by high glucose levels is mediated by epidermal growth factor receptor and phosphoinositide 3-kinase/Akt signalling in mesangial cells. Diabetologia 2007, 50:2008-2018.
22. Andrae J., Gallini R., Betsholtz C. Role of platelet-derived growth factors in physiology and medicine. Genes Dev. 2008, 22:1276-1312.
23. Scaltriti M., Baselga J. The epidermal growth factor receptor pathway: a model for targeted therapy. Clin. Cancer Res. 2006, 12:5268-5272.
24. Graf K., Xi X.P., Yang D., Fleck E., Hsueh W.A., Law R.E. Mitogen-activated protein kinase activation is involved in platelet-derived growth factor-directed migration by vascular smooth muscle cells. Hypertension 1997, 29:334-339.
25. Kim T.J., Yun Y.P. Antiproliferative activity of NQ304, a synthetic 1,4-naphthoquinone, is mediated via the suppressions of the PI3K/Akt and ERK1/2 signaling pathways in PDGF-BB-stimulated vascular smooth muscle cells. Vascul. Pharmacol. 2007, 46:43-51.
26. Belmadani S., Zerfaoui M., Boulares H.A., Palen D.I., Matrougui K. Microvessel vascular smooth muscle cells contribute to collagen type I deposition through ERK1/2 MAP kinase, alphavbeta3-integrin, and TGF-beta1 in response to ANG II and high glucose. Am. J. Physiol. Heart Circ. Physiol. 2008, 295:H69-H76.
27. Campbell M., Allen W.E., Sawyer C., Vanhaesebroeck B., Trimble E.R. Glucose-potentiated chemotaxis in human vascular smooth muscle is dependent on cross-talk between the PI3K and MAPK signaling pathways. Circ. Res. 2004, 95:380-388.
28. Chen H., Brahmbhatt S., Gupta A., Sharma A.C. Duration of streptozotocin-induced diabetes differentially affects p38-mitogen-activated protein kinase (MAPK) phosphorylation in renal and vascular dysfunction. Cardiovasc. Diabetol. 2005, 4:3.
29. Lappas G., Daou G.B., Anand-Srivastava M.B. Oxidative stress contributes to the enhanced expression of Gialpha proteins and adenylyl cyclase signaling in vascular smooth muscle cells from spontaneously hypertensive rats. J. Hypertens. 2005, 23:2251-2261.
30. Northcott C.A., Hayflick J., Watts S.W. Upregulated function of phosphatidylinositol-3-kinase in genetically hypertensive rats: a moderator of arterial hypercontractility. Clin. Exp. Pharmacol. Physiol. 2005, 32:851-858.
31. Yousif M.H. Phosphoinositide 3-kinase contributes to diabetes-induced abnormal vascular reactivity in rat perfused mesenteric bed. Cell Biochem. Funct. 2008, 26:451-458.
32. Anand-Srivastava M.B., Franks D.J., Cantin M., Genest J. Presence of "Ra" and "P"-site receptors for adenosine coupled to adenylate cyclase in cultured vascular smooth muscle cells. Biochem. Biophys. Res. Commun. 1982, 108:213-219.
33. Anand-Srivastava M.B., de C.J., Thibault C. DOCA-salt hypertensive rat hearts exhibit altered expression of G-proteins. Am. J. Hypertens. 1993, 6:72-75.
34. Mouawad R., Li Y., nand-Srivastava M.B. Atrial natriuretic peptide-C receptor-induced attenuation of adenylyl cyclase signaling activates phosphatidylinositol turnover in A10 vascular smooth muscle cells. Mol. Pharmacol. 2004, 65:917-924.
35. Dean N.M., Beaven M.A. Methods for the analysis of inositol phosphates. Anal. Biochem. 1989, 183:199-209.
36. Saito S., Frank G.D., Mifune M., Ohba M., Utsunomiya H., Motley E.D., et al. Ligand-independent trans-activation of the platelet-derived growth factor receptor by reactive oxygen species requires protein kinase C-delta and c-Src. J. Biol. Chem. 2002, 277:44695-44700.
37. Ushio-Fukai M., Griendling K.K., Becker P.L., Hilenski L., Halleran S., Alexander R.W. Epidermal growth factor receptor transactivation by angiotensin II requires reactive oxygen species in vascular smooth muscle cells. Arterioscler. Thromb. Vasc. Biol. 2001, 21:489-495.
38. Li Y., Descorbeth M., nand-Srivastava M.B. Role of oxidative stress in high glucose-induced decreased expression of Gialpha proteins and adenylyl cyclase signaling in vascular smooth muscle cells. Am. J. Physiol. Heart Circ. Physiol. 2008, 294:H2845-H2854.
39. Inaba T., Ishibashi S., Gotoda T., Kawamura M., Morino N., Nojima Y., et al. Enhanced expression of platelet-derived growth factor-beta receptor by high glucose. Involvement of platelet-derived growth factor in diabetic angiopathy. Diabetes 1996, 45:507-512.
40. Belmadani S., Palen D.I., Gonzalez-Villalobos R.A., Boulares H.A., Matrougui K. Elevated epidermal growth factor receptor phosphorylation induces resistance artery dysfunction in diabetic db/db mice. Diabetes 2008, 57:1629-1637.
41. Chan K.C., Wang C.J., Ho H.H., Chen H.M., Huang C.N. Simvastatin inhibits cell cycle progression in glucose-stimulated proliferation of aortic vascular smooth muscle cells by up-regulating cyclin dependent kinase inhibitors and p53. Pharmacol. Res. 2008, 58:247-256.
42. Ling H.Y., Hu B., Wang B.X., Zu X.Y., Feng S.D., Ou H.S., et al. Effects of rosiglitazone on the proliferation of vascular smooth muscle cell induced by high glucose. Cardiovasc. Drugs Ther. 2008, 22:453-460.
43. Jeong H.Y., Jeong H.Y., Kim C.D. p22phox-derived superoxide mediates enhanced proliferative capacity of diabetic vascular smooth muscle cells. Diabetes Res. Clin. Pract. 2004, 64:1-10.
44. Wang Y., Yan T., Wang Q., Wang W., Xu J., Wu X., et al. PKC-dependent extracellular signal-regulated kinase 1/2 pathway is involved in the inhibition of Ib on AngiotensinII-induced proliferation of vascular smooth muscle cells. Biochem. Biophys. Res. Commun. 2008, 375:151-155.
45. Kim T.J., Lee J.H., Lee J.J., Yu J.Y., Hwang B.Y., Ye S.K., et al. Corynoxeine isolated from the hook of Uncaria rhynchophylla inhibits rat aortic vascular smooth muscle cell proliferation through the blocking of extracellular signal regulated kinase 1/2 phosphorylation. Biol. Pharm. Bull. 2008, 31:2073-2078.
46. Radhakrishnan Y., Maile L.A., Ling Y., Graves L.M., Clemmons D.R. Insulin-like growth factor-I stimulates Shc-dependent phosphatidylinositol 3-kinase activation via Grb2-associated p85 in vascular smooth muscle cells. J. Biol. Chem. 2008, 283:16320-16331.
47. Hashim S., Li Y., Anand-Srivastava M.B. Small cytoplasmic domain peptides of natriuretic peptide receptor-C attenuate cell proliferation through Gialpha protein/MAP kinase/PI3-kinase/AKT pathways. Am. J. Physiol. Heart Circ. Physiol. 2006, 291:H3144-H3153.
48. Ge C., Anand-Srivastava M.B. Involvement of phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways in AII-mediated enhanced expression of Gi proteins in vascular smooth muscle cells. Biochem. Biophys. Res. Commun. 1998, 251:570-575.
49. Kim J., Lee C.K., Park H.J., Kim H.J., So H.H., Lee K.S., et al. Epidermal growth factor induces vasoconstriction through the phosphatidylinositol 3-kinase-mediated mitogen-activated protein kinase pathway in hypertensive rats. J. Pharmacol. Sci. 2006, 101:135-143.
50. Lee C.K., Lee H.M., Kim H.J., Park H.J., Won K.J., Roh H.Y., et al. Syk contributes to PDGF-BB-mediated migration of rat aortic smooth muscle cells via MAPK pathways. Cardiovasc. Res. 2007, 74:159-168.
51. Son D.J., Kang J., Kim T.J., Song H.S., Sung K.J., Yun d.Y., et al. Melittin, a major bioactive component of bee venom toxin, inhibits PDGF receptor beta-tyrosine phosphorylation and downstream intracellular signal transduction in rat aortic vascular smooth muscle cells. J.Toxicol.Environ.Health A 2007, 70:1350-1355.
52. Zhang L.J., Ma W.D., Yang Y., Wang R.M., Chen P., Yan J.B., et al. AcSDKP attenuates PDGF-induced cardiac fibroblasts proliferation and collagen expression: role of extracellular regulated protein kinase 1/2 pathway]. Zhonghua Xin Xue Guan Bing Za Zhi 2008, 36:444-448.
53. Suzaki Y., Yoshizumi M., Kagami S., Nishiyama A., Ozawa Y., Kyaw M., et al. BMK1 is activated in glomeruli of diabetic rats and in mesangial cells by high glucose conditions. Kidney Int. 2004, 65:1749-1760.
54. Montezano A.C., Callera G.E., Yogi A., He Y., Tostes R.C., He G., et al. Aldosterone and angiotensin II synergistically stimulate migration in vascular smooth muscle cells through c-Src-regulated redox-sensitive RhoA pathways. Arterioscler. Thromb. Vasc. Biol. 2008, 28:1511-1518.