메뉴 건너뛰기




Volumn 49, Issue 2, 2010, Pages 304-311

Nuclear receptor Nur77 suppresses inflammatory response dependent on COX-2 in macrophages induced by oxLDL

Author keywords

Atherosclerosis; COX 2; Macrophages; Nur77; OxLDL

Indexed keywords

CYCLOOXYGENASE 2; MERCAPTOPURINE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; NUCLEAR RECEPTOR NUR77; OXIDIZED LOW DENSITY LIPOPROTEIN; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR ALPHA;

EID: 77953722723     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2010.03.023     Document Type: Article
Times cited : (43)

References (32)
  • 1
    • 17644412023 scopus 로고    scopus 로고
    • Inflammation, atherosclerosis, and coronary artery disease
    • Hansson G.K. Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med 2005, 352:1685-1695.
    • (2005) N Engl J Med , vol.352 , pp. 1685-1695
    • Hansson, G.K.1
  • 2
    • 0037388984 scopus 로고    scopus 로고
    • Lack of Interleukin-1β decreases the severity of atherosclerosis in ApoE-deficient mice
    • Kirii Hirokazu, Niwa Tamikazu, Yamada Yasuhiro Lack of Interleukin-1β decreases the severity of atherosclerosis in ApoE-deficient mice. Arterioscler Thromb Vasc Biol 2003, 23:656-660.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 656-660
    • Kirii, H.1    Niwa, T.2    Yamada, Y.3
  • 3
    • 47649095117 scopus 로고    scopus 로고
    • Oxidized low-density lipoprotein induces differentiation of RAW264.7 murine macrophage cell line into dendritic-like cells
    • Shen L.H., Zhou L., Wang B.Y., Pu J., Hu L.H., Chai D.J., et al. Oxidized low-density lipoprotein induces differentiation of RAW264.7 murine macrophage cell line into dendritic-like cells. Atherosclerosis 2008, 199:257-264.
    • (2008) Atherosclerosis , vol.199 , pp. 257-264
    • Shen, L.H.1    Zhou, L.2    Wang, B.Y.3    Pu, J.4    Hu, L.H.5    Chai, D.J.6
  • 4
    • 23844468795 scopus 로고    scopus 로고
    • Induction of NR4A orphan nuclear receptor expression in macrophages in response to inflammatory stimuli
    • Pei L., Castrillo A., Chen M., Hoffmann A., Tontonoz P. Induction of NR4A orphan nuclear receptor expression in macrophages in response to inflammatory stimuli. J Biol Chem 2005, 280:29256-29262.
    • (2005) J Biol Chem , vol.280 , pp. 29256-29262
    • Pei, L.1    Castrillo, A.2    Chen, M.3    Hoffmann, A.4    Tontonoz, P.5
  • 5
    • 33749061994 scopus 로고    scopus 로고
    • Nuclear receptors Nur77, Nurr1, and NOR-1 expressed in atherosclerotic lesion macrophages reduce lipid loading and inflammatory responses
    • Bonta P.I., van Tiel C.M., Vos M., Pols T.W., van Thienen J.V., Ferreira V., et al. Nuclear receptors Nur77, Nurr1, and NOR-1 expressed in atherosclerotic lesion macrophages reduce lipid loading and inflammatory responses. Arterioscler Thromb Vasc Biol 2006, 26:2288-2294.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 2288-2294
    • Bonta, P.I.1    van Tiel, C.M.2    Vos, M.3    Pols, T.W.4    van Thienen, J.V.5    Ferreira, V.6
  • 6
    • 47949094965 scopus 로고    scopus 로고
    • Integration of metabolism and inflammation by lipid-activated nuclear receptors
    • Bensinger S.J., Tontonoz P. Integration of metabolism and inflammation by lipid-activated nuclear receptors. Nature 2008, 454:470-477.
    • (2008) Nature , vol.454 , pp. 470-477
    • Bensinger, S.J.1    Tontonoz, P.2
  • 7
    • 64249110598 scopus 로고    scopus 로고
    • Nur77 orphaned at birth but adopted by the nuclear factor kB signaling pathway
    • Evans Paul C. Nur77 orphaned at birth but adopted by the nuclear factor kB signaling pathway. Circ Res 2009, 104:707-709.
    • (2009) Circ Res , vol.104 , pp. 707-709
    • Evans, P.C.1
  • 8
    • 34047185458 scopus 로고    scopus 로고
    • NR4A nuclear receptors in atherosclerosis and vein-graft disease
    • Bonta P.I., Pols T.W., deVries C.J. NR4A nuclear receptors in atherosclerosis and vein-graft disease. Trends Cardiovasc Med 2007, 17:105-111.
    • (2007) Trends Cardiovasc Med , vol.17 , pp. 105-111
    • Bonta, P.I.1    Pols, T.W.2    deVries, C.J.3
  • 9
    • 0030977267 scopus 로고    scopus 로고
    • Functional redundancy of the Nur77 and Nor-1 orphan steroid receptors in T-cell apoptosis
    • Cheng L.E., Chan F.K., Cado D., Winoto A. Functional redundancy of the Nur77 and Nor-1 orphan steroid receptors in T-cell apoptosis. EMBO J 1997, 16:1865-1875.
    • (1997) EMBO J , vol.16 , pp. 1865-1875
    • Cheng, L.E.1    Chan, F.K.2    Cado, D.3    Winoto, A.4
  • 10
    • 1342306819 scopus 로고    scopus 로고
    • Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3
    • Lin B., Kolluri S.K., Lin F., Liu W., Han Y.H., Cao X., et al. Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3. Cell 2004, 116:527-540.
    • (2004) Cell , vol.116 , pp. 527-540
    • Lin, B.1    Kolluri, S.K.2    Lin, F.3    Liu, W.4    Han, Y.H.5    Cao, X.6
  • 12
    • 12344296637 scopus 로고    scopus 로고
    • The NR4A subfamily of nuclear receptors: new early genes regulated by growth factors in vascular cells
    • Martinez-Gonzalez J., Badimon L. The NR4A subfamily of nuclear receptors: new early genes regulated by growth factors in vascular cells. Cardiovasc Res 2005, 65:609-618.
    • (2005) Cardiovasc Res , vol.65 , pp. 609-618
    • Martinez-Gonzalez, J.1    Badimon, L.2
  • 14
    • 68549106140 scopus 로고    scopus 로고
    • Nuclear receptor Nur77 inhibits oxidized low density lipoprotein induced lipid loading in macrophages
    • Hu L.H., He B., Shen L.H., Zhou L., Pu J., Jiang L.S., et al. Nuclear receptor Nur77 inhibits oxidized low density lipoprotein induced lipid loading in macrophages. Zhonghua Xin Xue Guan Bing Za Zhi 2008, 36:1032-1036.
    • (2008) Zhonghua Xin Xue Guan Bing Za Zhi , vol.36 , pp. 1032-1036
    • Hu, L.H.1    He, B.2    Shen, L.H.3    Zhou, L.4    Pu, J.5    Jiang, L.S.6
  • 15
    • 0000061171 scopus 로고
    • Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids
    • Steinbrecher U.P., Parthasarathy S., Leake D.S., Witztum J.L., Steinberg D. Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids. Proc Natl Acad Sci 1984, 81:3883-3887.
    • (1984) Proc Natl Acad Sci , vol.81 , pp. 3883-3887
    • Steinbrecher, U.P.1    Parthasarathy, S.2    Leake, D.S.3    Witztum, J.L.4    Steinberg, D.5
  • 16
    • 44349186200 scopus 로고    scopus 로고
    • Oxidized low density lipoprotein activates peroxisome proliferator-activated receptor-α (PPARα) and PPARγ through MAPK-dependent COX-2 expression in macrophages
    • Taketa K., Matsumura T., Yano M., Ishii N., Senokuchi T., Motoshima H., et al. Oxidized low density lipoprotein activates peroxisome proliferator-activated receptor-α (PPARα) and PPARγ through MAPK-dependent COX-2 expression in macrophages. J Biol Chem 2008, 283:9852-9862.
    • (2008) J Biol Chem , vol.283 , pp. 9852-9862
    • Taketa, K.1    Matsumura, T.2    Yano, M.3    Ishii, N.4    Senokuchi, T.5    Motoshima, H.6
  • 17
    • 0037032817 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases
    • Johnson G.L., Lapadat R. Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science 2002, 298:1911-1912.
    • (2002) Science , vol.298 , pp. 1911-1912
    • Johnson, G.L.1    Lapadat, R.2
  • 18
    • 0043092126 scopus 로고    scopus 로고
    • The AF-1 domain of the orphan nuclear receptor NOR-1 mediates trans-activation, coactivator recruitment, and activation by the purine anti-metabolite, 6-mercaptopurine
    • Wansa K.D., Harris J.M., Yan G., Ordentlich P., Muscat G.E. The AF-1 domain of the orphan nuclear receptor NOR-1 mediates trans-activation, coactivator recruitment, and activation by the purine anti-metabolite, 6-mercaptopurine. J Biol Chem 2003, 278:24776-24790.
    • (2003) J Biol Chem , vol.278 , pp. 24776-24790
    • Wansa, K.D.1    Harris, J.M.2    Yan, G.3    Ordentlich, P.4    Muscat, G.E.5
  • 19
    • 23644460499 scopus 로고    scopus 로고
    • Cyclooxygenase-2 promotes early atherosclerotic lesion formation in ApoE-deficient and C57BL/6 mice
    • Burleigha M.E., Babaevb V.R., Yanceyb P.G., Majorb A.S., McCalebb J.L., Oatesa J.A., et al. Cyclooxygenase-2 promotes early atherosclerotic lesion formation in ApoE-deficient and C57BL/6 mice. J Mol Cell Cardiol 2005, 39(3):443-452.
    • (2005) J Mol Cell Cardiol , vol.39 , Issue.3 , pp. 443-452
    • Burleigha, M.E.1    Babaevb, V.R.2    Yanceyb, P.G.3    Majorb, A.S.4    McCalebb, J.L.5    Oatesa, J.A.6
  • 20
    • 0026434553 scopus 로고
    • Identification of the DNA binding site for NGFI-B by genetic selection in yeast
    • Wilson T.E., Fahrner T.J., Johnston M., Milbrandt J. Identification of the DNA binding site for NGFI-B by genetic selection in yeast. Science 1991, 252:1296-1300.
    • (1991) Science , vol.252 , pp. 1296-1300
    • Wilson, T.E.1    Fahrner, T.J.2    Johnston, M.3    Milbrandt, J.4
  • 21
    • 0037126018 scopus 로고    scopus 로고
    • Protective function of transcription factor TR3 orphan receptor in atherogenesis: decreased lesion formation in carotid artery ligation model in TR3 transgenic mice
    • Arkenbout E.K., de Waard V., van Bragt M., van Achterberg T.A., Grimbergen J.M., Pichon B., et al. Protective function of transcription factor TR3 orphan receptor in atherogenesis: decreased lesion formation in carotid artery ligation model in TR3 transgenic mice. Circulation 2002, 106:1530-1535.
    • (2002) Circulation , vol.106 , pp. 1530-1535
    • Arkenbout, E.K.1    de Waard, V.2    van Bragt, M.3    van Achterberg, T.A.4    Grimbergen, J.M.5    Pichon, B.6
  • 22
    • 33744738277 scopus 로고    scopus 로고
    • TR3 nuclear orphan receptor prevents cyclic stretch-induced proliferation of venous smooth muscle cells
    • de Waard V., Arkenbout E.K., Vos M., Mocking A.I., Niessen H.W., Stooker W., et al. TR3 nuclear orphan receptor prevents cyclic stretch-induced proliferation of venous smooth muscle cells. Am J Pathol 2006, 168:2027-2035.
    • (2006) Am J Pathol , vol.168 , pp. 2027-2035
    • de Waard, V.1    Arkenbout, E.K.2    Vos, M.3    Mocking, A.I.4    Niessen, H.W.5    Stooker, W.6
  • 23
    • 33846620640 scopus 로고    scopus 로고
    • Activation of nuclear receptor Nur77 by 6-mercaptopurine protects against neointima formation
    • Pires N.M., Pols T.W., de Vries M.R., van Tiel C.M., Bonta P.I., Vos M., et al. Activation of nuclear receptor Nur77 by 6-mercaptopurine protects against neointima formation. Circulation 2007, 115:493-500.
    • (2007) Circulation , vol.115 , pp. 493-500
    • Pires, N.M.1    Pols, T.W.2    de Vries, M.R.3    van Tiel, C.M.4    Bonta, P.I.5    Vos, M.6
  • 24
    • 33645062942 scopus 로고    scopus 로고
    • Orphan nuclear receptor TR3/Nur77 regulates VEGF-A-induced angiogenesis through its transcriptional activity
    • Zeng H., Qin L., Zhao D., Tan X., Manseau E.J., Van Hoang M., et al. Orphan nuclear receptor TR3/Nur77 regulates VEGF-A-induced angiogenesis through its transcriptional activity. J Exp Med 2006, 203:719-729.
    • (2006) J Exp Med , vol.203 , pp. 719-729
    • Zeng, H.1    Qin, L.2    Zhao, D.3    Tan, X.4    Manseau, E.J.5    Van Hoang, M.6
  • 25
    • 64249118416 scopus 로고    scopus 로고
    • The orphan nuclear receptor Nur77 suppresses endothelial cell activation through induction of IkBα expression
    • You B., Jiang Y.-Y., Chen S., Yan G., Sun J. The orphan nuclear receptor Nur77 suppresses endothelial cell activation through induction of IkBα expression. Circ Res 2009, 104:742-749.
    • (2009) Circ Res , vol.104 , pp. 742-749
    • You, B.1    Jiang, Y.-Y.2    Chen, S.3    Yan, G.4    Sun, J.5
  • 26
    • 0036035527 scopus 로고    scopus 로고
    • Inflammatory bio-markers and cardiovascular risk prediction
    • Blake G.J., Ridker P.M. Inflammatory bio-markers and cardiovascular risk prediction. J Intern Med 2002, 252:283-294.
    • (2002) J Intern Med , vol.252 , pp. 283-294
    • Blake, G.J.1    Ridker, P.M.2
  • 27
    • 4344652838 scopus 로고    scopus 로고
    • Apoptosis and plaque destabilization in atherosclerosis: the role of macrophage apoptosis induced by cholesterol
    • Tabas I. Apoptosis and plaque destabilization in atherosclerosis: the role of macrophage apoptosis induced by cholesterol. Cell Death Differ 2004, 11:s12-s16.
    • (2004) Cell Death Differ , vol.11
    • Tabas, I.1
  • 28
    • 0036855463 scopus 로고    scopus 로고
    • Protein kinase C alpha (PKC alpha): regulation and biological function
    • Nakashima S. Protein kinase C alpha (PKC alpha): regulation and biological function. J Biochem 2002, 132:669-675.
    • (2002) J Biochem , vol.132 , pp. 669-675
    • Nakashima, S.1
  • 30
    • 5644298876 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase and p38 mitogen-activated protein kinase mediate macrophage proliferation induced by oxidized low-density lipoprotein
    • Senokuchi T., Matsumura T., Sakai M., Matsuo T., Yano M., Kiritoshi S., et al. Extracellular signal-regulated kinase and p38 mitogen-activated protein kinase mediate macrophage proliferation induced by oxidized low-density lipoprotein. Atherosclerosis 2004, 176:233-245.
    • (2004) Atherosclerosis , vol.176 , pp. 233-245
    • Senokuchi, T.1    Matsumura, T.2    Sakai, M.3    Matsuo, T.4    Yano, M.5    Kiritoshi, S.6
  • 31
    • 33645411885 scopus 로고    scopus 로고
    • Regulation of macrophage inflammatory gene expression by the orphan nuclear receptor Nur77
    • Pei L., Castrillo A., Tontonoz P. Regulation of macrophage inflammatory gene expression by the orphan nuclear receptor Nur77. Mol Endocrinol 2006, 20:786-794.
    • (2006) Mol Endocrinol , vol.20 , pp. 786-794
    • Pei, L.1    Castrillo, A.2    Tontonoz, P.3
  • 32
    • 0037117652 scopus 로고    scopus 로고
    • Cyclooxygenase2 promotes early atherosclerotic lesion formation in LDL receptor-deficient mice
    • Burleigh M.E., Babaev V.R., Oates J.A., Harris R.C., Gautam S., Riendeau D., et al. Cyclooxygenase2 promotes early atherosclerotic lesion formation in LDL receptor-deficient mice. Circulation 2002, 105:1816-1823.
    • (2002) Circulation , vol.105 , pp. 1816-1823
    • Burleigh, M.E.1    Babaev, V.R.2    Oates, J.A.3    Harris, R.C.4    Gautam, S.5    Riendeau, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.