Mutation of tyrosine residue 857 in the PDGF β-receptor affects cell proliferation but not migration

Cellular Signalling

Volumn 22, Issue 9, 2010, Pages 1363-1368

  Wardega, Piotr ^a   Heldin, Carl Henrik ^a   Lennartsson, Johan ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

Autophosphorylation; Chemotaxis; PDGF; Proliferation; SHP 2; Y857

Indexed keywords

ADAPTOR PROTEIN; CBL PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHENYLALANINE; PHOSPHOTRANSFERASE; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PROTEIN ALIX; PROTEIN KINASE B; PROTEIN STAM; PROTEIN TYROSINE PHOSPHATASE SHP 2; TYROSINE; UNCLASSIFIED DRUG;

ANIMAL CELL; AORTA; ARTICLE; AUTOPHOSPHORYLATION; CELL MIGRATION; CELL PROLIFERATION; CELL SURFACE; CHEMOTAXIS; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; GENE MUTATION; IN VITRO STUDY; INTERNALIZATION; MITOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; SWINE; VASCULAR ENDOTHELIUM; WILD TYPE;

AMINO ACID SUBSTITUTION; ANIMALS; CELL PROLIFERATION; CELLS, CULTURED; CHEMOTAXIS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; MUTATION; PHOSPHORYLATION; PLATELET-DERIVED GROWTH FACTOR; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; SIGNAL TRANSDUCTION; SWINE; TYROSINE;

EID: 77953696895     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellsig.2010.05.004     Document Type: Article

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