Prevalence of hyperhomocysteinemia and related factors in a community-based health examination survey: A cross-sectional study

Journal of Preventive Medicine and Public Health

Volumn 42, Issue 5, 2009, Pages 337-342

  Soo, Jeong Kim ^a   Kyung, Sook Lim ^b   Mi, Sook Song ^c   Kang, Yeonji ^d   Soon, Young Lee ^d  

^a Korea University Ansan Hospital   (South Korea)

^b Korea Institute for Health and Social Affairs   (South Korea)

^c Ajou University   (South Korea)

^d Ajou University School of Medicine   (South Korea)

Author keywords

Adults; Cross sectional survey; Homocysteine; Hyperhomocysteinemia; Korea; Prevalence

Indexed keywords

HOMOCYSTEINE;

ADULT; AGED; ARTICLE; FEMALE; HUMAN; HYPERHOMOCYSTEINEMIA; KOREA; LIFESTYLE; MAJOR CLINICAL STUDY; MALE; MEDICAL EXAMINATION; PREVALENCE;

ADULT; AGE DISTRIBUTION; AGED; CARDIOVASCULAR DISEASES; CROSS-SECTIONAL STUDIES; FEMALE; HEALTH BEHAVIOR; HEALTH SURVEYS; HUMANS; HYPERHOMOCYSTEINEMIA; KOREA; LIPIDS; MALE; MIDDLE AGED; PREVALENCE; RISK FACTORS; SEX DISTRIBUTION;

EID: 77953664751     PISSN: 19758375     EISSN: None     Source Type: Journal    
DOI: 10.3961/jpmph.2009.42.5.337     Document Type: Article

References (38)

1. Wierzbicki AS. Homocysteine and cardiovascular disease: A review of the evidence. Diab Vasc Dis Res 2007; 4(2): 143-150.
2. Caldera A, Dec GW. Hyperhomocysteinemia and transplant coronary artery disease. Transplantation 2002; 74(10): 1359-1364. (Pubitemid 35379536)
3. Vollset SE, Refsum H, Tverdal A, Nygard O, Nordrehaug JE, Tell GS, et al. Plasma total homocysteine and cardiovascular and noncardiovascular mortality: The Hordaland Homocysteine Study. Am J Clin Nutr 2001; 74(1): 130-136. (Pubitemid 32574920)
4. Stampfer MJ, Malinow MR, Willett WC, Newcomer LM, Upson B, Ullmann D, et al. A prospective study of plasma homocyst(e)ine and risk of myocardial infarction in US physicians. JAMA 1992; 268(7): 877-881.
5. Arnesen E, Refsem H, Bonaa KH, Ueland PM, Forde OH, Nordrehaug JE. Serum total homocysteine and coronary heart disease. Int J Epidemiol 1995; 24(4): 704-709.
6. Boushey CJ, Beresford SA, Omenn GS, Motulsky AG. A quantitative assessment of plasma homocysteine as a risk factor for vascular disease: Probable benefits of increasing folic acid intakes. JAMA 1995; 274(13): 1049-1057.
7. Duell PB, Malinow MR. Homocyst(e)ine: An important risk factor for atherosclerotic vascular disease. Curr Opin Lipidol 1997; 8(1): 28-34. (Pubitemid 27148505)
8. Kim JU, Kim HJ, Choi BY. Normal value for serum homocysteine and the prevalence of hyperhomocysteinemia in a rural population. Korean J Epidemiol 2008; 30(1): 100-109. (Korean)
9. Nygard O, Refsum H, Ueland PM, Vollset SE. Major lifestyle determinants of plasma total homocysteine distribution: The Hordaland Homocysteine Study. Am J Clin Nutr 1998; 67(2): 263-270. (Pubitemid 28076718)
10. Jang YS, Cho EY, Lee JH, Jeong NS. Relationship between plasma homocysteine levels and cardiovascular risk factors in healthy men. Korean Circ 1999; 29(2): 135-145. (Korean)
11. Min HS. Folate status and plasma homocysteine concentration of Korea. Korean J Nutr 2001; 34(4): 393-400. (Korean)
12. 12 status in Korean adults. Korean J Community Nutr 2001; 6(3S): 507-515. (Korean)
13. 12 concentrations in coronary artery disease. Korean Circ J 1998; 28(4): 516-522. (Korean)
14. 6 status. J Nutr 2007; 137(2): 407-413. (Pubitemid 46213457)
15. Selhub J, Jacques PF, Rosenberg IH, Rogers G, Bowman BA, Gunter EW, et al. Serum total homocysteine concentrations in the third National Health and Nutrition Examination Survey (1991-1994): Population reference ranges and contribution of vitamin status to high serum concentrations. Ann Intern Med 1999; 131(5): 331-339.
16. de Bree A, Verschuren WM, Blom HJ, Kromhout D. Lifestyle factors and plasma homocysteine concentrations in a general population sample. Am J Epidemiol 2001; 154(2): 150-154. (Pubitemid 32643130)
17. Nygard O, Refsum H, Ueland PM, Stensvold I, Nordrehaug JE, Kvale G, et al. Coffee consumption and plasma total homocysteine: The Hordaland Homocysteine Study. Am J Clin Nutr 1997; 65(1): 136-143. (Pubitemid 27020471)
18. Jacques PF, Bostom AG, Wilson PW, Rich S, Rosenberg IH, Selhub J. Determinants of plasma total homocysteine concentration in the Framingham Offspring cohort. Am J Clin Nutr 2001; 73(3): 613-621. (Pubitemid 32176514)
19. Gaume V, Mougin F, Figard H, Simon-Rigaud ML, N' Guyen UN, Callier J, et al. Physical training decreases total plasma homocysteine and cysteine in middle-aged subjects. Ann Nutr Metab 2005; 49(2): 125-131. (Pubitemid 40827635)
20. Stryker WS, Kaplan LA, Stein EA, Stampfer MJ, Sober A, Willett WC. The relation of diet, cigarette smoking, and alcohol consumption to plasma beta-carotene and alpha-tocopherol levels. Am J Epidemiol 1988; 127(2): 283-296. (Pubitemid 18056382)
21. Refsum H, Ueland PM. Recent data are not in conflict with homocysteine as a cardiovascular risk factor. Curr Opin Lipidol 1998; 9(6): 533-539. (Pubitemid 29041447)
22. Schneede J, Refsum H, Ueland PM. Biological and environmental determinants of plasma homocysteine. Semin Thromb Hemost 2000; 26(3): 263-279. (Pubitemid 30703451)
23. Nygard O, Vollset SE, Refsum H, Stensvold I, Tverdal A, Nordrehaug JE, et al. Total plasma homocysteine and cardiovascular risk profile. The Hordaland Homocysteine Study. JAMA 1995; 274(19): 1526-1533.
24. Nurk E, Tell GS, Vollset SE, Nygard O, Refsum H, Nilsen RM, et al. Changes in lifestyle and plasma total homocysteine: The Hordaland Homocysteine Study. Am J Clin Nutr 2004; 79(5): 812-819. (Pubitemid 41103881)
25. Henriquez P, Doreste J, Deulofeu R, Fiuza MD, Serra-Majem L. Nutritional determinants of plasma total homocysteine distribution in the Canary Islands. Eur J Clin Nutr 2007; 61(1): 111-118. (Pubitemid 44921123)
26. Lee SY, Lee KJ, Kim SJ, Cho SW. Prevalence and risk factors for overlaps between gastroesophageal reflux disease, dyspepsia, and irritable bowel syndrome: A population-based study. Digestion 2009; 79(3): 196-201.
27. Doumas BT. How to Define and Determine Reference Intervals in the Clinical Laboratory; Approved Guideline, C28-A2.2nd ed. Wayne, PA: Clinical and Laboratory Standards Institute; 2000.
28. Ueland PM, Nygard O, Vollset SE, Refsum H. The hordaland homocysteine studies. Lipids 2001; 36(Suppl): S33-S39.
29. Oh KW, Lee WY, Ahn YB, Song KH, Yoo SJ, Yoon KH, et al. Homocysteine, folate, and methylenetetrahydrofolate reductase polymorphism in Korean normal subjects. Korean J Intern Med 1999; 57(6): 1030-1036. (Korean)
30. Ueland PM, Refsum H, Stabler SP, Malinow MR, Andersson A, Allen RH. Total homocysteine in plasma or serum: Methods and clinical applications. Clin Chem 1993; 39(9): 1764-1779. (Pubitemid 23277003)
31. Song WO, Chung CE, Chun OK, Cho S. Serum homocysteine concentration of US adults associated with fortified cereal consumption. J Am Coll Nutr 2005; 24(6): 503-509. (Pubitemid 43373175)
32. Ganji V, Kafai MR. Demographic, health, lifestyle, and blood vitamin determinants of serum total homocysteine concentrations in the third National Health and Nutrition Examination Survey, 1988-1994. Am J Clin Nutr 2003; 77(4): 826-833.
33. Saw SM, Yuan JM, Ong CN, Arakawa K, Lee HP, Coetzee GA, et al. Genetic, dietary, and other lifestyle determinants of plasma homocysteine concentrations in middle-aged and older Chinese men and women in Singapore. Am J Clin Nutr 2001; 73(2): 232-239. (Pubitemid 32111746)
34. Ubbink JB, Fehily AM, Pickering J, Elwood PC, Vermaak WJ. Homocysteine and ischaemic heart disease in the Caerphilly cohort. Atherosclerosis 1998; 140(2): 349-356. (Pubitemid 28535326)
35. Refsum H, Nurk E, Smith AD, Ueland PM, Gjesdal CG, Bjelland I, et al. The Hordaland Homocysteine Study: A community-based study of homocysteine, its determinants, and associations with disease. J Nutr 2006; 136(6 Suppl): 1731S-1740S. (Pubitemid 43765389)
36. Nieto FJ, Comstock GW, Chambless LE, Malinow RM. Coffee consumption and plasma homocyst(e)ine: Results from the Atherosclerosis Risk in Communities Study. Am J Clin Nutr 1997; 66(6): 1475-1477.
37. Stolzenberg-Solomon RZ, Miller ER 3rd, Maguire MG, Selhub J, Appel LJ. Association of dietary protein intake and coffee consumption with serum homocysteine concentrations in an older population. Am J Clin Nutr 1999; 69(3): 467-475.
38. Di Santolo M, Banfi G, Stel G, Cauci S. Association of recreational physical activity with homocysteine, folate and lipid markers in young women. Eur J Appl Physiol 2009; 105(1): 111-118.