Aberrant Epithelial Differentiation in Ovarian Cancer

Cancer Treatment and Research

Volumn 149, Issue , 2009, Pages 147-163

  Smith, Elizabeth R ^a   Cai, Kathy Qi ^a   Capo Chichi, Callinice D ^a   Xu, Xiang Xi ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR GATA;

CELL DIFFERENTIATION; EPITHELIUM CELL; HUMAN; NONHUMAN; OVARY CANCER; PRIORITY JOURNAL; PROTEIN FUNCTION; REVIEW; TUMOR DIFFERENTIATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CARCINOMA; CELL DEDIFFERENTIATION; CELL DIFFERENTIATION; CELL LINEAGE; ENDODERM; EPITHELIAL CELLS; FEMALE; GATA6 TRANSCRIPTION FACTOR; GENE SILENCING; HUMANS; NEOPLASM PROTEINS; NEOPLASTIC STEM CELLS; OVARIAN NEOPLASMS;

EID: 77953661371     PISSN: 09273042     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-0-387-98094-2_7     Document Type: Review

References (57)

1. Fusenig NE, Breitkreutz D, Boukamp P, Tomakidi P, Stark HJ. Differentiation and tumor progression. Recent Results Cancer Res. 1995;139:1-19.
2. Lynch RG. Differentiation and cancer: the conditional autonomy of phenotype. Proc Natl Acad Sci USA. 1995;92:647-648.
3. Rheinwald JG, Beckett MA. Defective terminal differentiation in culture as a consistent and selectable character of malignant human keratinocytes. Cell. 1980;22:629-632.
4. Richardson GS, Scully RE, Nikrui N, Nelson JH Jr. Common epithelial cancer of the ovary (2). N Engl J Med. 1985;312:474-483.
5. Capo-chichi CD, Roland IH, Vanderveer L, et al. Anomalous expression of epithelial differentiation-determining GATA factors in ovarian tumorigenesis. Cancer Res. 2003;63:4967-4977.
6. Caslini C, Capo-Chichi CD, Roland IH, Nicolas E, Yeung AT, Xu XX. Histone modifications silence the GATA transcription factor genes in ovarian cancer. Oncogene. 2006;25:5446-5461.
7. Bielinska M, Narita N, Wilson DB. Distinct roles for visceral endoderm during embryonic mouse development. Int J Dev Biol. 1999;43:183-205.
8. Lu CC, Brennan J, Robertson EJ. From fertilization to gastrulation: axis formation in the mouse embryo. Curr Opin Genet Dev. 2001;11:384-392.
9. Capo-Chichi CD, Rula ME, Smedberg JL, Vanderveer L, Parmacek MS, Morrisey EE, Godwin AK, Xu XX. Perception of differentiation cues by GATA factors in primitive endoderm lineage determination of mouse embryonic stem cells. Dev Biol. 2005;286: 574-586.
10. Molkentin JD. The zinc finger-containing transcription factors GATA-4, -5, and -6. Ubiquitously expressed regulators of tissue-specific gene expression. J Biol Chem . 2000;275:38949-38952.
11. Orkin SH. GATA-binding transcription factors in hematopoietic cells. Blood. 1992;80:575-581.
12. Simon MC. Gotta have GATA. Nat Genet. 1995;11:9-11.
13. Soudais C, Bielinska M, Heikinheimo M, et al. Targeted mutagenesis of the transcription factor GATA-4 gene in mouse embryonic stem cells disrupts visceral endoderm differentiation in vitro. Development. 1995;121:3877-3888.
14. Morrisey EE, Ip HS, Lu MM, Parmacek MS. GATA-6: a zinc finger transcription factor that is expressed in multiple cell lineages derived from lateral mesoderm. Dev Biol. 1996;177:309-322.
15. Fujikura J, Yamato E, Yonemura S, et al. Differentiation of embryonic stem cells is induced by GATA factors. Genes Dev. 2002;16:784-789.
16. Kuo CT, Morrisey EE, Anandappa R, et al. GATA4 transcription factor is required for ventral morphogenesis and heart tube formation. Genes Dev. 1997;11:1048-1060.
17. Watt AJ, Zhao R, Li J, Duncan SA. Development of the mammalian liver and ventral pancreas is dependent on GATA4. BMC Dev Biol. 2007;7:37.
18. Yang H, Lu MM, Zhang L, Whitsett JA, Morrisey EE. GATA6 regulates differentiation of distal lung epithelium. Development. 2002;129:2233-2246.
19. Jacobsen CM, Narita N, Bielinska M, Syder AJ, Gordon JI, Wilson DB. Genetic mosaic analysis reveals that GATA-4 is required for proper differentiation of mouse gastric epithelium. Dev Biol. 2002;241:34-46.
20. Gao X, Sedgwick T, Shi YB, Evans T. Distinct functions are implicated for the GATA-4, -5, and -6 transcription factors in the regulation of intestine epithelial cell differentiation. Mol Cell Biol. 1998;18:2901-2911.
21. Ketola I, Rahman N, Toppari J, et al. Expression and regulation of transcription factors GATA-4 and GATA-6 in developing mouse testis. Endocrinology. 1999;140:1470-1480.
22. Heikinheimo M, Ermolaeva M, Bielinska M, et al. Expression and hormonal regulation of transcription factors GATA-4 and GATA-6 in the mouse ovary. Endocrinology. 1997;138:3505-3514.
23. Laitinen MP, Anttonen M, Ketola I, Wilson DB, Ritvos O, Butzow R, Heikinheimo M. Transcription factors GATA-4 and GATA-6 and a GATA family cofactor, FOG-2, are expressed in human ovary and sex cord-derived ovarian tumors. J Clin Endocrinol Metab. 2000;85:3476-3483.
24. Asselin-Labat ML, Sutherland KD, Barker H, et al. Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation. Nat Cell Biol. 2007;9:201-209.
25. Kouros-Mehr H, Slorach EM, Sternlicht MD, Werb Z. GATA-3 maintains the differentiation of the luminal cell fate in the mammary gland. Cell. 2006;127:1041-1055.
26. Fazili Z, Sun W, Mittelstaedt S, Cohen C, Xu XX. Disabled-2 inactivation is an early step in ovarian tumorigenicity. Oncogene. 1999;18:3104-3113.
27. Morrisey EE, Musco S, Chen MY, Lu MM, Leiden JM, Parmacek MS. The gene encoding the mitogen-responsive phosphoprotein Dab2 is differentially regulated by GATA-6 and GATA-4 in the visceral endoderm. J Biol Chem. 2000;275: 19949-19954.
28. Yang DH, Smith ER, Cohen C, et al. Molecular events associated with dysplastic morphological transformation and initiation of ovarian tumorigenicity. Cancer. 2002; 94:2380-2392.
29. Sheng Z, Sun W, Smith E, Cohen C, Sheng Z, Xu XX. Restoration of positioning control following disabled-2 expression in ovarian and breast tumor cells. Oncogene. 2000;19: 4847-4854.
30. Bai Y, Akiyama Y, Nagasaki H, et al. Distinct expression of CDX2 and GATA4/5, development- related genes, in human gastric cancer cell lines. Mol Carcinog. 2000; 28:184-188.
31. Baylin S, Bestor TH. Altered methylation patterns in cancer cell genomes: cause or consequence? Cancer Cell. 2002;1:299-305.
32. Kouros-Mehr H, Bechis SK, Slorach EM, et al. GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model. Cancer Cell. 2008;13:141-152.
33. Kamnasaran D, Qian B, Hawkins C, Stanford WL, Guha A. GATA6 is an astrocytoma tumor suppressor gene identified by gene trapping of mouse glioma model. Proc Natl Acad Sci U S A. 2007;104:8053-8058.
34. Bleau AM, Holland EC. Trapping the mouse genome to hunt human alterations. Proc Natl Acad Sci U S A. 2007;104:7737-7738.
35. Wolffe AP. Chromatin and gene regulation at the onset of embryonic development. Reprod Nut Dev. 1996;36:581-606.
36. Jenuwein T, Allis CD. Translating the histone code. Science. 2001;293:1074-1080.
37. Gregory PD, Wagner K, Horz W. Histone acetylation and chromatin remodeling. Exp Cell Res. 2001;265:195-202.
38. Santos-Rosa H, Schneider R, Bannister AJ, et al. Active genes are tri-methylated at K4 of histone H3. Nature. 2002;419:407-411.
39. Schneider R, Bannister AJ, Myers FA, Thorne AW, Crane-Robinson C, Kouzarides T. Histone H3 lysine 4 methylation patterns in higher eukaryotic genes. Nat Cell Biol. 2004;6:73-77.
40. Lachner M, O'Carroll D, Rea S, Mechtler K, Jenuwein T. Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins. Nature. 2001;410:116-120.
41. Jones PA, Laird PW. Cancer epigenetics comes of age. Nat Genet. 1999;21:163-167.
42. Herman JG, Baylin SB, N Engl J Med. 2003;349:2042-2054.
43. Hake SB, Xiao A, Allis CD. Linking the epigenetic 'language' of covalent histone modifications to cancer. Br J Cancer. 2004;90:761-769.
44. Mutskov V, Felsenfeld G. Silencing of transgene transcription precedes methylation of promoter DNA and histone H3 lysine 9. EMBO J. 2004;23:138-149.
45. Bachman KE, Park BH, Rhee I, et al. Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene. Cancer Cell. 2003;3:89-95.
46. Wakana K, Akiyama Y, Aso T, Yuasa Y. Involvement of GATA-4/-5 transcription factors in ovarian carcinogenesis. Cancer Lett. 2006;241:281-288.
47. Dance AL, Miller M, Seragaki S, et al. Regulation of myosin-VI targeting to endocytic compartments. Traffic. 2004;5:798-813.
48. Yang DH, Cai KQ, Roland IH, Smith ER, Xu XX. Disabled-2 is an epithelial surface positioning gene. J Biol Chem. 2007;282:13114-13122.
49. Capo-chichi CD, Smith ER, Yang DH, et al. Dynamic alterations of extracellular environment of ovarian surface epithelial cells in pre-malignant transformation, tumorigenicity, and metastasis. Cancer. 2002;95:1802-1815.
50. Stenbeck F, Wasenius V-M. Basement membrane structures in tumors of the ovary. Eur J Obstet Gynec Reprod Biol. 1985;20:357-371.
51. Rossant J. Stem cells and early lineage development. Cell. 2008;132:527-531.
52. Lobo NA, Shimono Y, Qian D, Clarke MF. The biology of cancer stem cells. Annu Rev Cell Dev Biol.2007;23:675-699.
53. Polyak K. Breast cancer stem cells: a case of mistaken identity? Stem Cell Rev. 2007;3:107-109. (Pubitemid 350129711)
54. Bapat SA, Mali AM, Koppikar CB, Kurrey NK. Stem and progenitor-like cells contribute to the aggressive behavior of human epithelial ovarian cancer. Cancer Res. 2005;65:3025-3029.
55. Wani AA, Sharma N, Shouche YS, Bapat SA. Nuclear-mitochondrial genomic profiling reveals a pattern of evolution in epithelial ovarian tumor stem cells. Oncogene. 2006;25:6336-6344.
56. Szotek PP, Pieretti-Vanmarcke R, Masiakos PT, et al. Ovarian cancer side population defines cells with stem cell-like characteristics and Mullerian inhibiting substance responsiveness. Proc Natl Acad Sci U S A. 2006;103:11154-11159.
57. Bast RC Jr, Boyer CM, Jacobs I, et al. Cell growth regulation in epithelial ovarian cancer. Cancer. 1993;71:1597-1601.