From fertilization to gastrulation: Axis formation in the mouse embryo

Current Opinion in Genetics and Development

Volumn 11, Issue 4, 2001, Pages 384-392

  Lu, C C ^a   Brennan, J ^a   Robertson, E J ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLASTOCYST; CELL INTERACTION; CELL LINEAGE; ECTODERM; EMBRYO AXIS; EMBRYO PATTERN FORMATION; EMBRYO POLARITY; ENDODERM; FERTILIZATION; GASTRULATION; NIDATION; NONHUMAN; PRIMITIVE STREAK; PRIORITY JOURNAL; REVIEW; SPERMATOZOON PENETRATION;

EID: 0035427229     PISSN: 0959437X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-437X(00)00208-2     Document Type: Review

References (49)

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2. From cortical rotation to organizer gene expression: Toward a molecular explanation of axis specification in Xenopus
3. Role for sperm in spatial patterning of the early mouse embryo
4. The early blastocyst is bilaterally symmetrical and its axis of symmetry is aligned with the animal-vegetal axis of the zygote in the mouse
5. Animal and vegetal poles of the mouse egg predict the polarity of the embryonic axis, yet are nonessential for development
6. Fertile offspring derived from mammalian eggs lacking either animal or vegetal poles
7. Oct-4 transcription factor is differentially expressed in the mouse embryo during establishment of the first two extraembryonic cell lineages involved in implantation
8. Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4
9. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells
10. Taube nuss is a novel gene essential for the survival of pluripotent cells of early mouse embryos
11. Eomesodermin is required for mouse trophoblast development and mesoderm formation
12. Polarity of the mouse embryo is anticipated before implantation
13. The allocation of epiblast cells to ectodermal and germ-line lineages is influenced by the position of the cells in the gastrulating mouse embryo
14. Stage-specific tissue and cell interactions play key roles in mouse germ cell specification
15. Bmp4 is required for the generation of primordial germ cells in the mouse embryo
16. Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse
17. Nodal signalling in the epiblast patterns the early mouse embryo
18. Axis development and early asymmetry in mammals
19. Anterior primitive endoderm may be responsible for patterning the anterior neural plate in the mouse embryo
20. Hex: A homeobox gene revealing peri-implantation asymmetry in the mouse embryo and an early transient marker of endothelial cell precursors
21. Visceral endoderm mediates forebrain development by suppressing posteriorizing signals
22. Smad2 signaling in extraembryonic tissues determines anterior-posterior polarity of the early mouse embryo
23. HNF3β and Lim1 interact in the visceral endoderm to regulate primitive streak formation and anterior-posterior polarity in the mouse embryo
24. Visceral endoderm-restricted translation of Otx1 mediates recovery of Otx2 requirements for specification of anterior neural plate and normal gastrulation
25. Sequential roles for Otx2 in visceral endoderm and neuroectoderm for forebrain and midbrain induction and specification
26. Cripto is required for correct orientation of the anterior-posterior axis in the mouse embryo
27. Otx2 is required for visceral endoderm movement and for the restriction of posterior signals in the epiblast of the mouse embryo
28. Anterior patterning by synergistic activity of the early gastrula organizer and the anterior germ layer tissues of the mouse embryo
29. Requirement for Wnt3 in vertebrate axis formation
30. Hematopoietic induction and respecification of A-P identity by visceral endoderm signaling in the mouse embryo
31. Cooperation of endoderm-derived BMP2 and extraembryonic ectoderm-derived BMP4 in primordial germ cell generation in the mouse
32. The amnionless gene, essential for mouse gastrulation, encodes a visceral-endoderm-specific protein with an extracellular cysteine-rich domain
33. Induction of a second neural axis by the mouse node
34. Impact of node ablation on the morphogenesis of the body axis and the lateral asymmetry of the mouse embryo during early organogenesis
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37. Establishment and organization of germ layers in the gastrulating mouse embryo
38. The homeobox gene Hex is required in definitive endodermal tissues for normal forebrain, liver and thyroid formation
39. The morphogenetic role of midline mesendoderm and ectoderm in the development of the forebrain and the midbrain of the mouse embryo
40. FoxH1 (Fast) functions to specify the anterior primitive streak in the mouse
41. Induction of the mammalian node requires Arkadia function in the extraembryonic lineages
42. Arkadia enhances nodal-related signalling to induce mesendoderm
43. Nodal expression in the primitive endoderm is required for specification of the anterior axis during mouse gastrulation
44. Formation of the definitive endoderm in mouse is a Smad2-dependent process
45. The winged-helix transcription factor HNF-3β is required for notochord development in the mouse embryo
46. HNF-3β is essential for node and notochord formation in mouse development
47. Lim1 is required in both primitive streak-derived tissues and visceral endoderm for head formation in the mouse
48. The transcription factor FoxH1 (FAST) mediates Nodal signaling during anterior-posterior patterning and node formation in the mouse