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Volumn 2, Issue 6, 2010, Pages 965-973

Directed embryonic stem cell differentiation with small molecules

Author keywords

[No Author keywords available]

Indexed keywords

4 [4 (1,3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL]BENZAMIDE; ACTIVIN A; CARDIOGENOL C; CYMARIN; DORSOMORPHIN; DRUG; FLUOXETINE; GLYCOGEN SYNTHASE KINASE 3 INHIBITOR; ICARITIN; IDE 1; IMIPRAMINE; KHS 101; NATURAL PRODUCT; PLURIPOTIN; PURMORPHAMINE; RETINOIC ACID; SARMENTOGENIN; SELEGILINE; STAUPRIMIDE; SULFONYLHYDRAZONE; TWS 119; UNCLASSIFIED DRUG;

EID: 77953645136     PISSN: 17568919     EISSN: None     Source Type: Journal    
DOI: 10.4155/fmc.10.190     Document Type: Article
Times cited : (13)

References (33)
  • 1
    • 0019826665 scopus 로고
    • Establishment in culture of pluripotential cells from mouse embryos
    • Evans MJ, Kaufman MH. Establishment in culture of pluripotential cells from mouse embryos. Nature 292(5819), 154-156 (1981).
    • (1981) Nature , vol.292 , Issue.5819 , pp. 154-156
    • Evans, M.J.1    Kaufman, M.H.2
  • 2
    • 0001007610 scopus 로고
    • Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells
    • Martin GR. Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc. Natl Acad. Sci. USA 78(12), 7634-7638 (1981).
    • (1981) Proc. Natl Acad. Sci. USA , vol.78 , Issue.12 , pp. 7634-7638
    • Martin, G.R.1
  • 3
    • 0032491416 scopus 로고    scopus 로고
    • Embryonic stem cell lines derived from human blastocysts
    • Thomson JA, Itskovitz-Eldor J, Shapiro SS et al. Embryonic stem cell lines derived from human blastocysts. Science 282(5391), 1145-1147 (1998).
    • (1998) Science , vol.282 , Issue.5391 , pp. 1145-1147
    • Thomson, J.A.1    Itskovitz-Eldor, J.2    Shapiro, S.S.3
  • 4
    • 66149179125 scopus 로고    scopus 로고
    • Deconstructing stem cell tumorigenicity: A roadmap to safe regenerative medicine
    • Knoepfler PS. Deconstructing stem cell tumorigenicity: a roadmap to safe regenerative medicine. Stem Cells 27(5), 1050-1056 (2009).
    • (2009) Stem Cells , vol.27 , Issue.5 , pp. 1050-1056
    • Knoepfler, P.S.1
  • 5
    • 70349863066 scopus 로고    scopus 로고
    • Derivation of insulin-producing cells from human embryonic stem cells
    • van Hoof D, D'Amour KA, German MS. Derivation of insulin-producing cells from human embryonic stem cells. Stem Cell Res. 3(2-3), 73-87 (2009).
    • (2009) Stem Cell Res , vol.3 , Issue.2-3 , pp. 73-87
    • Van Hoof, D.1    D'Amour, K.A.2    German, M.S.3
  • 6
    • 15544383394 scopus 로고    scopus 로고
    • Embryonic stem cells: Prospects for developmental biology and cell therapy
    • Wobus AM, Boheler KR. Embryonic stem cells: prospects for developmental biology and cell therapy. Physiol. Rev. 85(2), 635-678 (2005).
    • (2005) Physiol. Rev. , vol.85 , Issue.2 , pp. 635-678
    • Wobus, A.M.1    Boheler, K.R.2
  • 7
    • 60849086260 scopus 로고    scopus 로고
    • Engineering the embryoid body microenvironment to direct embryonic stem cell differentiation
    • Bratt-Leal AM, Carpenedo RL, McDevitt TC. Engineering the embryoid body microenvironment to direct embryonic stem cell differentiation. Biotechnol. Prog. 25(1), 43-51 (2009).
    • (2009) Biotechnol. Prog. , vol.25 , Issue.1 , pp. 43-51
    • Bratt-Leal, A.M.1    Carpenedo, R.L.2    McDevitt, T.C.3
  • 8
    • 67649410314 scopus 로고    scopus 로고
    • Small molecules for stem cells
    • Kochegarov A. Small molecules for stem cells. Expert Opin. Ther. Pat. 19(3), 275-281 (2009).
    • (2009) Expert Opin. Ther. Pat. , vol.19 , Issue.3 , pp. 275-281
    • Kochegarov, A.1
  • 9
    • 69849089425 scopus 로고    scopus 로고
    • Synthesis at the interface of chemistry and biology
    • Wu X, Schultz PG. Synthesis at the interface of chemistry and biology. J. Am. Chem. Soc. 131(35), 12497-12515 (2009).
    • (2009) J. Am. Chem. Soc. , vol.131 , Issue.35 , pp. 12497-12515
    • Wu, X.1    Schultz, P.G.2
  • 10
    • 65349086683 scopus 로고    scopus 로고
    • A small molecule primes embryonic stem cells for differentiation
    • Zhu S, Wurdak H, Wang J et al. A small molecule primes embryonic stem cells for differentiation. Cell Stem Cell 4(5), 416-426 (2009).
    • (2009) Cell Stem Cell , vol.4 , Issue.5 , pp. 416-426
    • Zhu, S.1    Wurdak, H.2    Wang, J.3
  • 11
    • 0347915660 scopus 로고    scopus 로고
    • Nodal signaling and vertebrate germ layer formation
    • Weng W, Stemple DL. Nodal signaling and vertebrate germ layer formation. Birth Defects Res. C Embryo Today 69(4), 325-332 (2003).
    • (2003) Birth Defects Res. C Embryo Today , vol.69 , Issue.4 , pp. 325-332
    • Weng, W.1    Stemple, D.L.2
  • 12
    • 62949210744 scopus 로고    scopus 로고
    • Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells
    • Borowiak M, Maehr R, Chen S et al. Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells. Cell Stem Cell 4(4), 348-358 (2009).
    • (2009) Cell Stem Cell , vol.4 , Issue.4 , pp. 348-358
    • Borowiak, M.1    Maehr, R.2    Chen, S.3
  • 14
    • 62549088238 scopus 로고    scopus 로고
    • Enhanced co-expression of b-tubulin III and choline acetyltransferase in neurons from mouse embryonic stem cells promoted by icaritin in an estrogen receptor-independent manner
    • Wang Z, Wang H, Wu J et al. Enhanced co-expression of b-tubulin III and choline acetyltransferase in neurons from mouse embryonic stem cells promoted by icaritin in an estrogen receptor-independent manner. Chem. Biol. Interact. 179(2-3), 375-385 (2009).
    • (2009) Chem. Biol. Interact. , vol.179 , Issue.2-3 , pp. 375-385
    • Wang, Z.1    Wang, H.2    Wu, J.3
  • 15
    • 0037596751 scopus 로고    scopus 로고
    • Synthetic small molecules that control stem cell fate
    • Ding S, Wu TY, Brinker A et al. Synthetic small molecules that control stem cell fate. Proc. Natl Acad. Sci. USA 100(13), 7632-7637 (2003).
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , Issue.13 , pp. 7632-7637
    • Ding, S.1    Wu, T.Y.2    Brinker, A.3
  • 16
    • 51449091152 scopus 로고    scopus 로고
    • Dorsomorphin, a selective small molecule inhibitor of BMP signaling, promotes cardiomyogenesis in embryonic stem cells
    • Hao J, Daleo MA, Murphy CK et al. Dorsomorphin, a selective small molecule inhibitor of BMP signaling, promotes cardiomyogenesis in embryonic stem cells. PLoS One 3(8), E2904 (2008).
    • (2008) PLoS One , vol.3 , Issue.8
    • Hao, J.1    Ma, D.2    Murphy, C.K.3
  • 17
    • 43149119978 scopus 로고    scopus 로고
    • Cardiogenic small molecules that enhance myocardial repair by stem cells
    • Sadek H, Hannack B, Choe E et al. Cardiogenic small molecules that enhance myocardial repair by stem cells. Proc. Natl Acad. Sci. USA 105(16), 6063-6068 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , Issue.16 , pp. 6063-6068
    • Sadek, H.1    Hannack, B.2    Choe, E.3
  • 18
    • 1242336840 scopus 로고    scopus 로고
    • Small molecules that induce cardiomyogenesis in embryonic stem cells
    • Wu X, Ding S, Ding Q, Gray NS, Schultz PG. Small molecules that induce cardiomyogenesis in embryonic stem cells. J. Am. Chem. Soc. 126(6), 1590-1591 (2004).
    • (2004) J. Am. Chem. Soc. , vol.126 , Issue.6 , pp. 1590-1591
    • Wu, X.1    Ding, S.2    Ding, Q.3    Gray, N.S.4    Schultz, P.G.5
  • 19
    • 44349152907 scopus 로고    scopus 로고
    • High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells
    • Desbordes SC, Placantonakis DG, Ciro A et al. High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells. Cell Stem Cell 2(6), 602-612 (2008).
    • (2008) Cell Stem Cell , vol.2 , Issue.6 , pp. 602-612
    • Desbordes, S.C.1    Placantonakis, D.G.2    Ciro, A.3
  • 20
    • 33751239783 scopus 로고    scopus 로고
    • Self-renewal of embryonic stem cells by a small molecule
    • Chen S, Do JT, Zhang Q et al. Self-renewal of embryonic stem cells by a small molecule. Proc. Natl Acad. Sci. USA 103(46), 17266-17271 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , Issue.46 , pp. 17266-17271
    • Chen, S.1    Do, J.T.2    Zhang, Q.3
  • 21
    • 33646576842 scopus 로고    scopus 로고
    • Genetic selection of SOX1GFP-expressing neural precursors removes residual tumorigenic pluripotent stem cells and attenuates tumor formation after transplantation
    • Chung S, Shin BS, Hedlund E et al. Genetic selection of SOX1GFP-expressing neural precursors removes residual tumorigenic pluripotent stem cells and attenuates tumor formation after transplantation. J. Neurochem. 97(5), 1467-1480 (2006).
    • (2006) J. Neurochem. , vol.97 , Issue.5 , pp. 1467-1480
    • Chung, S.1    Shin, B.S.2    Hedlund, E.3
  • 22
    • 72849140856 scopus 로고    scopus 로고
    • Assessment of embryonic myocardial cell differentiation using a dual fluorescent reporter system
    • McMullen NM, Zhang F, Pasumarthi KB. Assessment of embryonic myocardial cell differentiation using a dual fluorescent reporter system. J. Cell Mol. Med. 13(9A), 2834-2842 (2009).
    • (2009) J. Cell Mol. Med. , vol.13 , Issue.9 A , pp. 2834-2842
    • McMullen, N.M.1    Zhang, F.2    Pasumarthi, K.B.3
  • 23
    • 40549132870 scopus 로고    scopus 로고
    • Mouse ES cell-derived cardiac precursor cells are multipotent and facilitate identification of novel cardiac genes
    • Christoforou N, Miller RA, Hill CM, Jie CC, McCallion AS, Gearhart JD. Mouse ES cell-derived cardiac precursor cells are multipotent and facilitate identification of novel cardiac genes. J. Clin. Invest. 118(3), 894-903 (2008).
    • (2008) J. Clin. Invest. , vol.118 , Issue.3 , pp. 894-903
    • Christoforou, N.1    Miller, R.A.2    Hill, C.M.3    Jie, C.C.4    McCallion, A.S.5    Gearhart, J.D.6
  • 24
    • 33750846133 scopus 로고    scopus 로고
    • Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells
    • D'Amour KA, Bang AG, Eliazer S et al. Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells. Nat. Biotechnol. 24(11), 1392-1401 (2006).
    • (2006) Nat. Biotechnol. , vol.24 , Issue.11 , pp. 1392-1401
    • D'Amour, K.A.1    Bang, A.G.2    Eliazer, S.3
  • 26
    • 41849151748 scopus 로고    scopus 로고
    • Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo
    • Kroon E, Martinson LA, Kadoya K et al. Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo. Nat. Biotechnol. 26(4), 443-452 (2008).
    • (2008) Nat. Biotechnol. , vol.26 , Issue.4 , pp. 443-452
    • Kroon, E.1    Martinson, L.A.2    Kadoya, K.3
  • 27
    • 4644250693 scopus 로고    scopus 로고
    • Purmorphamine induces osteogenesis by activation of the hedgehog signaling pathway
    • Wu X, Walker J, Zhang J, Ding S, Schultz PG. Purmorphamine induces osteogenesis by activation of the hedgehog signaling pathway. Chem. Biol. 11(9), 1229-1238 (2004).
    • (2004) Chem. Biol. , vol.11 , Issue.9 , pp. 1229-1238
    • Wu, X.1    Walker, J.2    Zhang, J.3    Ding, S.4    Schultz, P.G.5
  • 28
    • 22144446030 scopus 로고    scopus 로고
    • Programmable DNA binding oligomers for control of transcription
    • Dervan PB, Doss RM, Marques MA. Programmable DNA binding oligomers for control of transcription. Curr. Med. Chem. Anticancer Agents 5(4), 373-387 (2005).
    • (2005) Curr. Med. Chem. Anticancer Agents , vol.5 , Issue.4 , pp. 373-387
    • Dervan, P.B.1    Doss, R.M.2    Ma, M.3
  • 29
    • 45749158648 scopus 로고    scopus 로고
    • Identification of the cellular targets of bioactive small organic molecules using affinity reagents
    • Leslie BJ, Hergenrother PJ. Identification of the cellular targets of bioactive small organic molecules using affinity reagents. Chem. Soc. Rev. 37(7), 1347-1360 (2008).
    • (2008) Chem. Soc. Rev. , vol.37 , Issue.7 , pp. 1347-1360
    • Leslie, B.J.1    Hergenrother, P.J.2
  • 30
    • 5644255981 scopus 로고    scopus 로고
    • Photo-affinity labeling strategies in identifying the protein ligands of bioactive small molecules: Examples of targeted synthesis of drug analog photoprobes
    • Colca JR, Harrigan GG. Photo-affinity labeling strategies in identifying the protein ligands of bioactive small molecules: examples of targeted synthesis of drug analog photoprobes. Comb. Chem. High Throughput Screen. 7(7), 699-704 (2004).
    • (2004) Comb. Chem. High Throughput Screen. , vol.7 , Issue.7 , pp. 699-704
    • Colca, J.R.1    Harrigan, G.G.2
  • 31
    • 36849087030 scopus 로고    scopus 로고
    • Antidepressant drugs reverse the loss of adult neural stem cells following chronic stress
    • Hitoshi S, Maruta N, Higashi M, Kumar A, Kato N, Ikenaka K. Antidepressant drugs reverse the loss of adult neural stem cells following chronic stress. J. Neurosci. Res. 85(16), 3574-3585 (2007).
    • (2007) J. Neurosci. Res. , vol.85 , Issue.16 , pp. 3574-3585
    • Hitoshi, S.1    Maruta, N.2    Higashi, M.3    Kumar, A.4    Kato, N.5    Ikenaka, K.6
  • 32
    • 31044449947 scopus 로고    scopus 로고
    • A synthetic small molecule that induces neuronal differentiation of adult hippocampal neural progenitor cells
    • Warashina M, Min KH, Kuwabara T et al. A synthetic small molecule that induces neuronal differentiation of adult hippocampal neural progenitor cells. Angew Chem. Int. Ed. Engl. 45(4), 591-593 (2006).
    • (2006) Angew Chem. Int. Ed. Engl. , vol.45 , Issue.4 , pp. 591-593
    • Warashina, M.1    Min, K.H.2    Kuwabara, T.3
  • 33
    • 74949133926 scopus 로고    scopus 로고
    • Progress toward the clinical application of patient-specific pluripotent stem cells
    • Kiskinis E, Eggan K. Progress toward the clinical application of patient-specific pluripotent stem cells. J. Clin. Invest. 120(1), 51-59 (2010).
    • (2010) J. Clin. Invest. , vol.120 , Issue.1 , pp. 51-59
    • Kiskinis, E.1    Eggan, K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.