-
1
-
-
0019826665
-
Establishment in culture of pluripotential cells from mouse embryos
-
Evans MJ, Kaufman MH. Establishment in culture of pluripotential cells from mouse embryos. Nature 292(5819), 154-156 (1981).
-
(1981)
Nature
, vol.292
, Issue.5819
, pp. 154-156
-
-
Evans, M.J.1
Kaufman, M.H.2
-
2
-
-
0001007610
-
Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells
-
Martin GR. Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc. Natl Acad. Sci. USA 78(12), 7634-7638 (1981).
-
(1981)
Proc. Natl Acad. Sci. USA
, vol.78
, Issue.12
, pp. 7634-7638
-
-
Martin, G.R.1
-
3
-
-
0032491416
-
Embryonic stem cell lines derived from human blastocysts
-
Thomson JA, Itskovitz-Eldor J, Shapiro SS et al. Embryonic stem cell lines derived from human blastocysts. Science 282(5391), 1145-1147 (1998).
-
(1998)
Science
, vol.282
, Issue.5391
, pp. 1145-1147
-
-
Thomson, J.A.1
Itskovitz-Eldor, J.2
Shapiro, S.S.3
-
4
-
-
66149179125
-
Deconstructing stem cell tumorigenicity: A roadmap to safe regenerative medicine
-
Knoepfler PS. Deconstructing stem cell tumorigenicity: a roadmap to safe regenerative medicine. Stem Cells 27(5), 1050-1056 (2009).
-
(2009)
Stem Cells
, vol.27
, Issue.5
, pp. 1050-1056
-
-
Knoepfler, P.S.1
-
5
-
-
70349863066
-
Derivation of insulin-producing cells from human embryonic stem cells
-
van Hoof D, D'Amour KA, German MS. Derivation of insulin-producing cells from human embryonic stem cells. Stem Cell Res. 3(2-3), 73-87 (2009).
-
(2009)
Stem Cell Res
, vol.3
, Issue.2-3
, pp. 73-87
-
-
Van Hoof, D.1
D'Amour, K.A.2
German, M.S.3
-
6
-
-
15544383394
-
Embryonic stem cells: Prospects for developmental biology and cell therapy
-
Wobus AM, Boheler KR. Embryonic stem cells: prospects for developmental biology and cell therapy. Physiol. Rev. 85(2), 635-678 (2005).
-
(2005)
Physiol. Rev.
, vol.85
, Issue.2
, pp. 635-678
-
-
Wobus, A.M.1
Boheler, K.R.2
-
7
-
-
60849086260
-
Engineering the embryoid body microenvironment to direct embryonic stem cell differentiation
-
Bratt-Leal AM, Carpenedo RL, McDevitt TC. Engineering the embryoid body microenvironment to direct embryonic stem cell differentiation. Biotechnol. Prog. 25(1), 43-51 (2009).
-
(2009)
Biotechnol. Prog.
, vol.25
, Issue.1
, pp. 43-51
-
-
Bratt-Leal, A.M.1
Carpenedo, R.L.2
McDevitt, T.C.3
-
8
-
-
67649410314
-
Small molecules for stem cells
-
Kochegarov A. Small molecules for stem cells. Expert Opin. Ther. Pat. 19(3), 275-281 (2009).
-
(2009)
Expert Opin. Ther. Pat.
, vol.19
, Issue.3
, pp. 275-281
-
-
Kochegarov, A.1
-
9
-
-
69849089425
-
Synthesis at the interface of chemistry and biology
-
Wu X, Schultz PG. Synthesis at the interface of chemistry and biology. J. Am. Chem. Soc. 131(35), 12497-12515 (2009).
-
(2009)
J. Am. Chem. Soc.
, vol.131
, Issue.35
, pp. 12497-12515
-
-
Wu, X.1
Schultz, P.G.2
-
10
-
-
65349086683
-
A small molecule primes embryonic stem cells for differentiation
-
Zhu S, Wurdak H, Wang J et al. A small molecule primes embryonic stem cells for differentiation. Cell Stem Cell 4(5), 416-426 (2009).
-
(2009)
Cell Stem Cell
, vol.4
, Issue.5
, pp. 416-426
-
-
Zhu, S.1
Wurdak, H.2
Wang, J.3
-
11
-
-
0347915660
-
Nodal signaling and vertebrate germ layer formation
-
Weng W, Stemple DL. Nodal signaling and vertebrate germ layer formation. Birth Defects Res. C Embryo Today 69(4), 325-332 (2003).
-
(2003)
Birth Defects Res. C Embryo Today
, vol.69
, Issue.4
, pp. 325-332
-
-
Weng, W.1
Stemple, D.L.2
-
12
-
-
62949210744
-
Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells
-
Borowiak M, Maehr R, Chen S et al. Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells. Cell Stem Cell 4(4), 348-358 (2009).
-
(2009)
Cell Stem Cell
, vol.4
, Issue.4
, pp. 348-358
-
-
Borowiak, M.1
Maehr, R.2
Chen, S.3
-
13
-
-
62149125434
-
Highly efficient neural conversion of human ES and IPS cells by dual inhibition of SMAD signaling
-
Chambers SM, Fasano CA, Papapetrou EP, Tomishima M, Sadelain M, Studer L. Highly efficient neural conversion of human ES and IPS cells by dual inhibition of SMAD signaling. Nat. Biotechnol. 27(3), 275-280 (2009).
-
(2009)
Nat. Biotechnol.
, vol.27
, Issue.3
, pp. 275-280
-
-
Chambers, S.M.1
Fasano, C.A.2
Papapetrou, E.P.3
Tomishima, M.4
Sadelain, M.5
Studer, L.6
-
14
-
-
62549088238
-
Enhanced co-expression of b-tubulin III and choline acetyltransferase in neurons from mouse embryonic stem cells promoted by icaritin in an estrogen receptor-independent manner
-
Wang Z, Wang H, Wu J et al. Enhanced co-expression of b-tubulin III and choline acetyltransferase in neurons from mouse embryonic stem cells promoted by icaritin in an estrogen receptor-independent manner. Chem. Biol. Interact. 179(2-3), 375-385 (2009).
-
(2009)
Chem. Biol. Interact.
, vol.179
, Issue.2-3
, pp. 375-385
-
-
Wang, Z.1
Wang, H.2
Wu, J.3
-
15
-
-
0037596751
-
Synthetic small molecules that control stem cell fate
-
Ding S, Wu TY, Brinker A et al. Synthetic small molecules that control stem cell fate. Proc. Natl Acad. Sci. USA 100(13), 7632-7637 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, Issue.13
, pp. 7632-7637
-
-
Ding, S.1
Wu, T.Y.2
Brinker, A.3
-
16
-
-
51449091152
-
Dorsomorphin, a selective small molecule inhibitor of BMP signaling, promotes cardiomyogenesis in embryonic stem cells
-
Hao J, Daleo MA, Murphy CK et al. Dorsomorphin, a selective small molecule inhibitor of BMP signaling, promotes cardiomyogenesis in embryonic stem cells. PLoS One 3(8), E2904 (2008).
-
(2008)
PLoS One
, vol.3
, Issue.8
-
-
Hao, J.1
Ma, D.2
Murphy, C.K.3
-
17
-
-
43149119978
-
Cardiogenic small molecules that enhance myocardial repair by stem cells
-
Sadek H, Hannack B, Choe E et al. Cardiogenic small molecules that enhance myocardial repair by stem cells. Proc. Natl Acad. Sci. USA 105(16), 6063-6068 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, Issue.16
, pp. 6063-6068
-
-
Sadek, H.1
Hannack, B.2
Choe, E.3
-
18
-
-
1242336840
-
Small molecules that induce cardiomyogenesis in embryonic stem cells
-
Wu X, Ding S, Ding Q, Gray NS, Schultz PG. Small molecules that induce cardiomyogenesis in embryonic stem cells. J. Am. Chem. Soc. 126(6), 1590-1591 (2004).
-
(2004)
J. Am. Chem. Soc.
, vol.126
, Issue.6
, pp. 1590-1591
-
-
Wu, X.1
Ding, S.2
Ding, Q.3
Gray, N.S.4
Schultz, P.G.5
-
19
-
-
44349152907
-
High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells
-
Desbordes SC, Placantonakis DG, Ciro A et al. High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells. Cell Stem Cell 2(6), 602-612 (2008).
-
(2008)
Cell Stem Cell
, vol.2
, Issue.6
, pp. 602-612
-
-
Desbordes, S.C.1
Placantonakis, D.G.2
Ciro, A.3
-
20
-
-
33751239783
-
Self-renewal of embryonic stem cells by a small molecule
-
Chen S, Do JT, Zhang Q et al. Self-renewal of embryonic stem cells by a small molecule. Proc. Natl Acad. Sci. USA 103(46), 17266-17271 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, Issue.46
, pp. 17266-17271
-
-
Chen, S.1
Do, J.T.2
Zhang, Q.3
-
21
-
-
33646576842
-
Genetic selection of SOX1GFP-expressing neural precursors removes residual tumorigenic pluripotent stem cells and attenuates tumor formation after transplantation
-
Chung S, Shin BS, Hedlund E et al. Genetic selection of SOX1GFP-expressing neural precursors removes residual tumorigenic pluripotent stem cells and attenuates tumor formation after transplantation. J. Neurochem. 97(5), 1467-1480 (2006).
-
(2006)
J. Neurochem.
, vol.97
, Issue.5
, pp. 1467-1480
-
-
Chung, S.1
Shin, B.S.2
Hedlund, E.3
-
22
-
-
72849140856
-
Assessment of embryonic myocardial cell differentiation using a dual fluorescent reporter system
-
McMullen NM, Zhang F, Pasumarthi KB. Assessment of embryonic myocardial cell differentiation using a dual fluorescent reporter system. J. Cell Mol. Med. 13(9A), 2834-2842 (2009).
-
(2009)
J. Cell Mol. Med.
, vol.13
, Issue.9 A
, pp. 2834-2842
-
-
McMullen, N.M.1
Zhang, F.2
Pasumarthi, K.B.3
-
23
-
-
40549132870
-
Mouse ES cell-derived cardiac precursor cells are multipotent and facilitate identification of novel cardiac genes
-
Christoforou N, Miller RA, Hill CM, Jie CC, McCallion AS, Gearhart JD. Mouse ES cell-derived cardiac precursor cells are multipotent and facilitate identification of novel cardiac genes. J. Clin. Invest. 118(3), 894-903 (2008).
-
(2008)
J. Clin. Invest.
, vol.118
, Issue.3
, pp. 894-903
-
-
Christoforou, N.1
Miller, R.A.2
Hill, C.M.3
Jie, C.C.4
McCallion, A.S.5
Gearhart, J.D.6
-
24
-
-
33750846133
-
Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells
-
D'Amour KA, Bang AG, Eliazer S et al. Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells. Nat. Biotechnol. 24(11), 1392-1401 (2006).
-
(2006)
Nat. Biotechnol.
, vol.24
, Issue.11
, pp. 1392-1401
-
-
D'Amour, K.A.1
Bang, A.G.2
Eliazer, S.3
-
25
-
-
28644448149
-
Efficient differentiation of human embryonic stem cells to definitive endoderm
-
D'Amour KA, Agulnick AD, Eliazer S, Kelly OG, Kroon E, Baetge EE. Efficient differentiation of human embryonic stem cells to definitive endoderm. Nat. Biotechnol. 23(12), 1534-1541 (2005).
-
(2005)
Nat. Biotechnol.
, vol.23
, Issue.12
, pp. 1534-1541
-
-
D'Amour, K.A.1
Agulnick, A.D.2
Eliazer, S.3
Kelly, O.G.4
Kroon, E.5
Baetge, E.E.6
-
26
-
-
41849151748
-
Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo
-
Kroon E, Martinson LA, Kadoya K et al. Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo. Nat. Biotechnol. 26(4), 443-452 (2008).
-
(2008)
Nat. Biotechnol.
, vol.26
, Issue.4
, pp. 443-452
-
-
Kroon, E.1
Martinson, L.A.2
Kadoya, K.3
-
27
-
-
4644250693
-
Purmorphamine induces osteogenesis by activation of the hedgehog signaling pathway
-
Wu X, Walker J, Zhang J, Ding S, Schultz PG. Purmorphamine induces osteogenesis by activation of the hedgehog signaling pathway. Chem. Biol. 11(9), 1229-1238 (2004).
-
(2004)
Chem. Biol.
, vol.11
, Issue.9
, pp. 1229-1238
-
-
Wu, X.1
Walker, J.2
Zhang, J.3
Ding, S.4
Schultz, P.G.5
-
28
-
-
22144446030
-
Programmable DNA binding oligomers for control of transcription
-
Dervan PB, Doss RM, Marques MA. Programmable DNA binding oligomers for control of transcription. Curr. Med. Chem. Anticancer Agents 5(4), 373-387 (2005).
-
(2005)
Curr. Med. Chem. Anticancer Agents
, vol.5
, Issue.4
, pp. 373-387
-
-
Dervan, P.B.1
Doss, R.M.2
Ma, M.3
-
29
-
-
45749158648
-
Identification of the cellular targets of bioactive small organic molecules using affinity reagents
-
Leslie BJ, Hergenrother PJ. Identification of the cellular targets of bioactive small organic molecules using affinity reagents. Chem. Soc. Rev. 37(7), 1347-1360 (2008).
-
(2008)
Chem. Soc. Rev.
, vol.37
, Issue.7
, pp. 1347-1360
-
-
Leslie, B.J.1
Hergenrother, P.J.2
-
30
-
-
5644255981
-
Photo-affinity labeling strategies in identifying the protein ligands of bioactive small molecules: Examples of targeted synthesis of drug analog photoprobes
-
Colca JR, Harrigan GG. Photo-affinity labeling strategies in identifying the protein ligands of bioactive small molecules: examples of targeted synthesis of drug analog photoprobes. Comb. Chem. High Throughput Screen. 7(7), 699-704 (2004).
-
(2004)
Comb. Chem. High Throughput Screen.
, vol.7
, Issue.7
, pp. 699-704
-
-
Colca, J.R.1
Harrigan, G.G.2
-
31
-
-
36849087030
-
Antidepressant drugs reverse the loss of adult neural stem cells following chronic stress
-
Hitoshi S, Maruta N, Higashi M, Kumar A, Kato N, Ikenaka K. Antidepressant drugs reverse the loss of adult neural stem cells following chronic stress. J. Neurosci. Res. 85(16), 3574-3585 (2007).
-
(2007)
J. Neurosci. Res.
, vol.85
, Issue.16
, pp. 3574-3585
-
-
Hitoshi, S.1
Maruta, N.2
Higashi, M.3
Kumar, A.4
Kato, N.5
Ikenaka, K.6
-
32
-
-
31044449947
-
A synthetic small molecule that induces neuronal differentiation of adult hippocampal neural progenitor cells
-
Warashina M, Min KH, Kuwabara T et al. A synthetic small molecule that induces neuronal differentiation of adult hippocampal neural progenitor cells. Angew Chem. Int. Ed. Engl. 45(4), 591-593 (2006).
-
(2006)
Angew Chem. Int. Ed. Engl.
, vol.45
, Issue.4
, pp. 591-593
-
-
Warashina, M.1
Min, K.H.2
Kuwabara, T.3
-
33
-
-
74949133926
-
Progress toward the clinical application of patient-specific pluripotent stem cells
-
Kiskinis E, Eggan K. Progress toward the clinical application of patient-specific pluripotent stem cells. J. Clin. Invest. 120(1), 51-59 (2010).
-
(2010)
J. Clin. Invest.
, vol.120
, Issue.1
, pp. 51-59
-
-
Kiskinis, E.1
Eggan, K.2
|