Ultraviolet irradiation induces thrombospondin-1 which attenuates type I procollagen downregulation in human dermal fibroblasts

Journal of Dermatological Science

Volumn 59, Issue 1, 2010, Pages 16-24

  Seo, Jo Eun ^a,b,c,d   Kim, Sangmin ^a,b,c   Shin, Mi Hee ^a,b,c   Kim, Mi Sun ^a,b,c   Eun, Hee Chul ^a,b,c   Park, Chi Hyun ^a,b,c   Chung, Jin Ho ^a,b,c  

^a Seoul National University College of Medicine   (South Korea)

^b Seoul National University   (South Korea)

^c Seoul National University Hospital   (South Korea)

^d Inje University   (South Korea)

Author keywords

Dermis; Fibroblasts; Procollagen; TSP 1; UV irradiation

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PROCOLLAGEN; PROCOLLAGEN TYPE 1; SMAD3 PROTEIN; SMALL INTERFERING RNA; THROMBOSPONDIN 1; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; COLLAGEN TYPE 1; MTOR PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE; SIGNAL PEPTIDE; TARGET OF RAPAMYCIN KINASE;

ADULT; ARTICLE; ATTENUATION; BUTTOCK; DERMIS; DOWN REGULATION; ENZYME REPRESSION; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO CULTURE; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; ULTRAVIOLET IRRADIATION; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; CHEMISTRY; METABOLISM; RADIATION RESPONSE; SKIN; ULTRAVIOLET RADIATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADULT; COLLAGEN TYPE I; DOWN-REGULATION; FIBROBLASTS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; PROTEIN-SERINE-THREONINE KINASES; RNA, MESSENGER; SKIN; THROMBOSPONDIN 1; ULTRAVIOLET RAYS; PHOSPHATIDYLINOSITOL 3-KINASES; TOR SERINE-THREONINE KINASES;

EID: 77953614906     PISSN: 09231811     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2010.04.010     Document Type: Article

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