The effect of social isolation on rat brain expression of genes associated with endocannabinoid signaling

Brain Research

Volumn 1343, Issue , 2010, Pages 153-167

  Robinson, Stephanie A ^a   Loiacono, Richard E ^a   Christopoulos, Arthur ^a   Sexton, Patrick M ^a   Malone, Daniel T ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

Endocannabinoid; Social isolation

Indexed keywords

ACYLGLYCEROL LIPASE; ANANDAMIDE; CANNABINOID 1 RECEPTOR; ENDOCANNABINOID; FATTY ACID AMIDASE; ISOENZYME; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN REGION; CONTROLLED STUDY; ENZYME SYNTHESIS; GENE EXPRESSION; GENETIC ASSOCIATION; HISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; NONHUMAN; PERINATAL PERIOD; PREFRONTAL CORTEX; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; SOCIAL ISOLATION; SUBSTANTIA NIGRA; THALAMUS; VENTRAL TEGMENTUM;

ANIMALS; BRAIN CHEMISTRY; DISEASE MODELS, ANIMAL; ENDOCANNABINOIDS; GENE EXPRESSION REGULATION; MALE; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SOCIAL ISOLATION; STRESS, PSYCHOLOGICAL; UP-REGULATION;

RATTUS;

EID: 77953612299     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2010.04.031     Document Type: Article

References (74)

1. Baker D., Pryce G., Giovannoni G., and Thompson A.J. The therapeutic potential of cannabis. Lancet Neurol. 2 (2003) 291-298
2. Ballmaier M., Bortolato M., Rizzetti C., Zoli M., Gessa G., Heinz A., and Spano P. Cannabinoid receptor antagonists counteract sensorimotor gating deficits in the phencyclidine model of psychosis. Neuropsychopharmacology 32 (2007) 2098-2107
3. Bisogno T., Howell F., Williams G., Minassi A., Cascio M.G., Ligresti A., Matias I., Schiano-Moriello A., Paul P., Williams E.J., Gangadharan U., Hobbs C., Di Marzo V., and Doherty P. Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain. J. Cell Biol. 163 (2003) 463-468
4. Braff D.L., Geyer M.A., and Swerdlow N.R. Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies. Psychopharmacology (Berl) 156 (2001) 234-258
5. Brenes Saenz J.C., Villagra O.R., and Fornaguera Trias J. Factor analysis of Forced Swimming test, Sucrose Preference test and Open Field test on enriched, social and isolated reared rats. Behav. Brain Res. 169 (2006) 57-65
6. Brusco A., Tagliaferro P.A., Saez T., and Onaivi E.S. Ultrastructural localization of neuronal brain CB2 cannabinoid receptors. Ann. N. Y. Acad. Sci. 1139 (2008) 450-457
7. Cabranes A., Pryce G., Baker D., and Fernandez-Ruiz J. Changes in CB1 receptors in motor-related brain structures of chronic relapsing experimental allergic encephalomyelitis mice. Brain Res. 1107 (2006) 199-205
8. Cravatt B.F., Demarest K., Patricelli M.P., Bracey M.H., Giang D.K., Martin B.R., and Lichtman A.H. Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase. PNAS 98 (2001) 9371-9376
9. De Marchi N., De Petrocellis L., Orlando P., Daniele F., Fezza F., and Di Marzo V. Endocannabinoid signalling in the blood of patients with schizophrenia. Lipids Health Dis. 2 (2003) 5
10. 3H]CP-55940 binding in the human central nervous system: regional specific changes in density of cannabinoid-1 receptors associated with schizophrenia and cannabis use. Neuroscience 103 (2001) 9-15
11. Deng C., Han M., and Huang X.F. No changes in densities of cannabinoid receptors in the superior temporal gyrus in schizophrenia. Neurosci. Bull. 23 (2007) 341-347
12. Di Marzo V., Fontana A., Cadas H., Schinelli S., Cimino G., Schwartz J.C., and Piomelli D. Formation and inactivation of endogenous cannabinoid anandamide in central neurons. Nature 372 (1994) 686-691
13. Di Marzo V., Bifulco M., and De Petrocellis L. The endocannabinoid system and its therapeutic exploitation. Nat. Rev. Drug Discov. 3 (2004) 771-784
14. Dinh T.P., Carpenter D., Leslie F.M., Freund T.F., Katona I., Sensi S.L., Kathuria S., and Piomelli D. Brain monoglyceride lipase participating in endocannabinoid inactivation. Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 10819-10824
15. Duarte J.M., Nogueira C., Mackie K., Oliveira C.R., Cunha R.A., and Kofalvi A. Increase of cannabinoid CB1 receptor density in the hippocampus of streptozotocin-induced diabetic rats. Exp. Neurol. 204 (2007) 479-484
16. Egertova M., Simon G.M., Cravatt B.F., and Elphick M.R. Localization of N-acyl phosphatidylethanolamine phospholipase D (NAPE-PLD) expression in mouse brain: a new perspective on N-acylethanolamines as neural signaling molecules. J. Comp. Neurol. 506 (2008) 604-615
17. Eggan S.M., Hashimoto T., and Lewis D.A. Reduced cortical cannabinoid 1 receptor messenger RNA and protein expression in schizophrenia. Arch. Gen. Psychiatry 65 (2008) 772-784
18. Elsohly M.A., and Slade D. Chemical constituents of marijuana: the complex mixture of natural cannabinoids. Life Sci. 78 (2005) 539-548
19. Emrich H.M., Leweke F.M., and Schneider U. Towards a cannabinoid hypothesis of schizophrenia: cognitive impairments due to dysregulation of the endogenous cannabinoid system. Pharmacol. Biochem. Behav. 56 (1997) 803-807
20. Fan F., Tao Q., Abood M., and Martin B.R. Cannabinoid receptor down-regulation without alteration of the inhibitory effect of CP 55,940 on adenylyl cyclase in the cerebellum of CP 55,940-tolerant mice. Brain Res. 706 (1996) 13-20
21. Felder C.C., Nielsen A., Briley E.M., Palkovits M., Priller J., Axelrod J., Nguyen D.N., Richardson J.M., Riggin R.M., Koppel G.A., Paul S.M., and Becker G.W. Isolation and measurement of the endogenous cannabinoid receptor agonist, anandamide, in brain and peripheral tissues of human and rat. FEBS Lett. 393 (1996) 231-235
22. Fone K.C., and Porkess M.V. Behavioural and neurochemical effects of post-weaning social isolation in rodents-relevance to developmental neuropsychiatric disorders. Neurosci. Biobehav. Rev. 32 (2008) 1087-1102
23. Geyer M.A., Wilkinson L.S., Humby T., and Robbins T.W. Isolation rearing of rats produces a deficit in prepulse inhibition of acoustic startle similar to that in schizophrenia. Biol. Psychiatry 34 (1993) 361-372
24. Geyer M.A., Krebs-Thomson K., Braff D.L., and Swerdlow N.R. Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review. Psychopharmacology (Berl) 156 (2001) 117-154
25. Giuffrida A., Beltramo M., and Piomelli D. Mechanisms of endocannabinoid inactivation: biochemistry and pharmacology. J. Pharmacol. Exp. Ther. 298 (2001) 7-14
26. Giuffrida A., Leweke F.M., Gerth C.W., Schreiber D., Koethe D., Faulhaber J., Klosterkotter J., and Piomelli D. Cerebrospinal anandamide levels are elevated in acute schizophrenia and are inversely correlated with psychotic symptoms. Neuropsychopharmacology 29 (2004) 2108-2114
27. Goutopoulos A., and Makriyannis A. From cannabis to cannabinergics: new therapeutic opportunities. Pharmacol. Ther. 95 (2002) 103-117
28. Gray J.A. Dopamine release in the nucleus accumbens: the perspective from aberrations of consciousness in schizophrenia. Neuropsychologia 33 (1995) 1143-1153
29. Grimsey N.L., Goodfellow C.E., Scotter E.L., Dowie M.J., Glass M., and Graham E.S. Specific detection of CB1 receptors; cannabinoid CB1 receptor antibodies are not all created equal!. J. Neurosci. Methods 171 (2008) 78-86
30. Gundlach A.L., and O'Shea R.D. Quantitative analysis of in situ hybridization histochemistry. In in situ hybridization protocols for the brain. In: Wisden W., and Morris B.J. (Eds). International Review of Neurobiology Vol. 47 (2002), Academic Press, London 135-170
31. Hall F.S., Huang S., Fong G.W., Pert A., and Linnoila M. Effects of isolation-rearing on voluntary consumption of ethanol, sucrose and saccharin solutions in Fawn Hooded and Wistar rats. Psychopharmacology (Berl) 139 (1998) 210-216
32. Harte M.K., Powell S.B., Reynolds L.M., Swerdlow N.R., Geyer M.A., and Reynolds G.P. Reduced N-acetylaspartate in the temporal cortex of rats reared in isolation. Biol. Psychiatry 56 (2004) 296-299
33. Heidbreder C.A., Weiss I.C., Domeney A.M., Pryce C., Homberg J., Hedou G., Feldon J., Moran M.C., and Nelson P. Behavioral, neurochemical and endocrinological characterization of the early social isolation syndrome. Neuroscience 100 (2000) 749-768
34. Herkenham M., Lynn A.B., Little M.D., Johnson M.R., Melvin L.S., de Costa B.R., and Rice K.C. Cannabinoid receptor localization in brain. Proc. Natl. Acad. Sci. U. S. A. 87 (1990) 1932-1936
35. Ishiguro H., Horiuchi Y., Ishikawa M., Koga M., Imai K., Suzuki Y., Morikawa M., Inada T., Watanabe Y., Takahashi M., Someya T., Ujike H., Iwata N., Ozaki N., Onaivi E.S., Kunugi H., Sasaki T., Itokawa M., Arai M., Niizato K., Iritani S., Naka I., Ohashi J., Kakita A., Takahashi H., Nawa H., and Arinami T. Brain cannabinoid CB2 receptor in schizophrenia. Biol. Psychiatry 67 10 (2010) 974-982
36. Karlsson M., Contreras J.A., Hellman U., Tornqvist H., and Holm C. cDNA cloning, tissue distribution, and identification of the catalytic triad of monoglyceride lipase. Evolutionary relationship to esterases, lysophospholipases, and haloperoxidases. J. Biol. Chem. 272 (1997) 27218-27223
37. 1 cannabinoid receptor in the anterior cingulate cortex in schizophrenia, bipolar disorder, and major depression. J. Neural Transm. 114 (2007) 1055-1063
38. Lafourcade M., Elezgarai I., Mato S., Bakiri Y., Grandes P., and Manzoni O.J. Molecular components and functions of the endocannabinoid system in mouse prefrontal cortex. PLoS ONE 2 (2007) e709
39. Lapiz M.D., Fulford A., Muchimapura S., Mason R., Parker T., and Marsden C.A. Influence of postweaning social isolation in the rat on brain development, conditioned behaviour and neurotransmission. Ross. Fiziol. Zh. Im. I. M. Sechenova 87 (2001) 730-751
40. 1 receptors in the basal ganglia of a transgenic model of Huntington's disease. Brain Res. 929 (2002) 236-242
41. Leung D., Saghatelian A., Simon G.M., and Cravatt B.F. Inactivation of N-acyl phosphatidylethanolamine phospholipase D reveals multiple mechanisms for the biosynthesis of endocannabinoids. Biochemistry 45 (2006) 4720-4726
42. Leweke F.M., Giuffrida A., Wurster U., Emrich H.M., and Piomelli D. Elevated endogenous cannabinoids in schizophrenia. NeuroReport 10 (1999) 1665-1669
43. Leweke F.M., Giuffrida A., Koethe D., Schreiber D., Nolden B.M., Kranaster L., Neatby M.A., Schneider M., Gerth C.W., Hellmich M., Klosterkotter J., and Piomelli D. Anandamide levels in cerebrospinal fluid of first-episode schizophrenic patients: impact of cannabis use. Schizophr. Res. 94 (2007) 29-36
44. Li N., Wu X., and Li L. Chronic administration of clozapine alleviates reversal-learning impairment in isolation-reared rats. Behav. Pharmacol. 18 (2007) 135-145
45. Ligresti A., Cascio M.G., and Di Marzo V. Endocannabinoid metabolic pathways and enzymes. Curr. Drug Targets CNS Neurol. Disord. 4 (2005) 615-623
46. Lukkes J.L., Watt M.J., Lowry C.A., and Forster G.L. Consequences of post-weaning social isolation on anxiety behavior and related neural circuits in rodents. Front. Behav. Neurosci. 3 (2009) 18
47. Mailleux P., and Vanderhaeghen J.J. Distribution of neuronal cannabinoid receptor in the adult rat brain: a comparative receptor binding radioautography and in situ hybridization histochemistry. Neuroscience 48 (1992) 655-668
48. Malone D.T., Long L.E., and Taylor D.A. The effect of SR 141716 and apomorphine on sensorimotor gating in Swiss mice. Pharmacol. Biochem. Behav. 77 (2004) 839-845
49. 9-tetrahydrocannabinol on sensorimotor gating in socially isolated rats. Behav. Brain Res. 166 (2006) 101-109
50. 2 receptor and fatty acid amide hydrolase expression in rats. Neuroscience 152 (2008) 265-272
51. Matsuda L.A., Bonner T.I., and Lolait S.J. Cannabinoid receptors: which cells, where, how, and why?. NIDA Res. Monogr. 126 (1992) 48-56
52. Matsuda L.A., Bonner T.I., and Lolait S.J. Localization of cannabinoid receptor mRNA in rat brain. J. Comp. Neurol. 327 (1993) 535-550
53. McKinney M.K., and Cravatt B.F. Structure and function of fatty acid amide hydrolase. Annu. Rev. Biochem. 74 (2005) 411-432
54. Muchimapura S., Fulford A.J., Mason R., and Marsden C.A. Isolation rearing in the rat disrupts the hippocampal response to stress. Neuroscience 112 (2002) 697-705
55. Muchimapura S., Mason R., and Marsden C.A. Effect of isolation rearing on pre- and post-synaptic serotonergic function in the rat dorsal hippocampus. Synapse 47 (2003) 209-217
56. Munro S., Thomas K.L., and Abu-Shaar M. Molecular characterization of a peripheral receptor for cannabinoids. Nature 365 (1993) 61-65
57. Newell K.A., Deng C., and Huang X.F. Increased cannabinoid receptor density in the posterior cingulate cortex in schizophrenia. Exp. Brain Res. 172 (2006) 556-560
58. Okamoto Y., Morishita J., Tsuboi K., Tonai T., and Ueda N. Molecular characterization of a phospholipase D generating anandamide and its congeners. J. Biol. Chem. 279 (2004) 5298-5305
59. Pacher P., Batkai S., and Kunos G. The endocannabinoid system as an emerging target of pharmacotherapy. Pharmacol. Rev. 58 (2006) 389-462
60. Paxinos G., and Watson C. The Rat Brain in Stereotaxic Coordinates. Vol (1998), Academic Press Inc, California
61. Pradet-Balade B., Boulme F., Beug H., Mullner E.W., and Garcia-Sanz J.A. Translation control: bridging the gap between genomics and proteomics?. Trends Biochem. Sci. 26 (2001) 225-229
62. Schrijver N.C., and Wurbel H. Early social deprivation disrupts attentional, but not affective, shifts in rats. Behav. Neurosci. 115 (2001) 437-442
63. Simon G.M., and Cravatt B.F. Anandamide biosynthesis catalyzed by the phosphodiesterase GDE1 and detection of glycerophospho-N-acyl ethanolamine precursors in mouse brain. J. Biol. Chem. 283 (2008) 9341-9349
64. Swerdlow N.R., Geyer M.A., and Braff D.L. Neural circuit regulation of prepulse inhibition of startle in the rat: current knowledge and future challenges. Psychopharmacology (Berl) 156 (2001) 194-215
65. Thomas E.A., Cravatt B.F., Danielson P.E., Gilula N.B., and Sutcliffe J.G. Fatty acid amide hydrolase, the degradative enzyme for anandamide and oleamide, has selective distribution in neurons within the rat central nervous system. J. Neurosci. Res. 50 (1997) 1047-1052
66. 1 receptors in the rat central nervous system. Neuroscience 83 (1998) 393-411
67. Turner C.E., Elsohly M.A., and Boeren E.G. Constituents of Cannabis sativa L.: XVII. A review of the natural constituents. J. Nat. Prod. 43 (1980) 169-234
68. Ueda N., Kurahashi Y., Yamamoto S., and Tokunaga T. Partial purification and characterization of the porcine brain enzyme hydrolyzing and synthesizing anandamide. J. Biol. Chem. 270 (1995) 23823-23827
69. 1 cannabinoid receptors in postmortem frontal cortex of subjects with schizophrenia: effect of antipsychotic treatment. Psychopharmacology (Berl) 206 (2009) 313-324
70. Van Den Berg C.L., Van Ree J.M., and Spruijt B.M. Sequential analysis of juvenile isolation-induced decreased social behavior in the adult rat. Physiol. Behav. 67 (1999) 483-488
71. Van den Buuse M., Garner B., and Koch M. Neurodevelopmental animal models of schizophrenia: effects on prepulse inhibition. Curr. Mol. Med. 3 (2003) 459-471
72. Wilkinson L.S., Killcross S.S., Humby T., Hall F.S., Geyer M.A., and Robbins T.W. Social isolation in the rat produces developmentally specific deficits in prepulse inhibition of the acoustic startle response without disrupting latent inhibition. Neuropsychopharmacology 10 (1994) 61-72
73. 1 receptor. J. Neurosci. 26 (2006) 4740-4751
74. 1 receptors is increased in the anterior cingulate cortex in schizophrenia. Prog. Neuropsychopharmacol. Biol. Psychiatry 28 (2004) 355-360