메뉴 건너뛰기




Volumn 95, Issue 2, 2002, Pages 103-117

From cannabis to cannabinergics: New therapeutic opportunities

Author keywords

Anandamide; Cannabimimetics; Cannabinergics; Cannabinoid receptors; CB1; Therapeutics

Indexed keywords

2 ARACHIDONOYLGLYCEROL; 2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; 3 (2 IODO 5 NITROBENZOYL) 1 (1 METHYL 2 PIPERIDINYLMETHYL)INDOLE; 4 (1,1 DIMETHYLHEPTYL) 1',2',3',4',5',6' HEXAHYDRO 2,3' DIHYDROXY 6' (3 HYDROXYPROPYL)BIPHENYL; 4 [4 (1,1 DIMETHYLHEPTYL) 2,6 DIMETHOXYPHENYL] 6,6 DIMETHYLBICYCLO[3.1.1]HEPT 2 EN 2 YLMETHANOL; 5 (1,1 DIMETHYLHEPTYL) 2 (3 HYDROXY 7 HYDROXYMETHYLDECAHYDRO 1 NAPHTHYL)PHENOL; 5 (4 CHLORO 3 METHYLPHENYL) 1 (4 METHYLBENZYL) N (1,3,3 TRIMETHYLBICYCLO[2.2.1]HEPTAN 2 YL) 3 PYRAZOLECARBOXAMIDE; 6 IODO 3 (4 METHOXYBENZOYL) 2 METHYL 1 (2 MORPHOLINOETHYL)INDOLE; AM 1116; AM 374; AM 919; AMG 3; AMIDASE; ANANDAMIDE; ARACHIDONYL TRIFLUOROMETHYL KETONE; ARACHIDONYLETHANOLAMIDE AMIDOHYDROLASE; CANNABINOID; CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; CANNABIS; DRONABINOL; HEXADECYLSULFONYL FLUORIDE; LIGAND; METHANANDAMIDE; N (4 HYDROXYPHENYL)ARACHIDONAMIDE; NABILONE; O 1064; RECEPTOR PROTEIN; RIMONABANT; UNCLASSIFIED DRUG;

EID: 0036669789     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0163-7258(02)00250-4     Document Type: Review
Times cited : (100)

References (117)
  • 2
    • 0032468166 scopus 로고    scopus 로고
    • Anandamide, an endogenous cannabinoid has a very low physical dependence potential
    • Aceto M.D., Scates S.M., Razdan R.K., Martin B.R. Anandamide, an endogenous cannabinoid has a very low physical dependence potential. J Pharmacol Exp Ther. 287:1998;598-605.
    • (1998) J Pharmacol Exp Ther , vol.287 , pp. 598-605
    • Aceto, M.D.1    Scates, S.M.2    Razdan, R.K.3    Martin, B.R.4
  • 3
    • 0030738512 scopus 로고    scopus 로고
    • Selective inhibition of sucrose and ethanol intake by SR 141716, an antagonist of central cannabinoid (CB1) receptors
    • Arnone M., Maruani J., Chaperon F., Thiébot M.-H., Poncelet M., Soubrié P., Le Fur G. Selective inhibition of sucrose and ethanol intake by SR 141716, an antagonist of central cannabinoid (CB1) receptors. Psychopharmacology. 132:1997;104-106.
    • (1997) Psychopharmacology , vol.132 , pp. 104-106
    • Arnone, M.1    Maruani, J.2    Chaperon, F.3    Thiébot, M.-H.4    Poncelet, M.5    Soubrié, P.6    Le Fur, G.7
  • 4
    • 0034594905 scopus 로고    scopus 로고
    • Cannabinoids control spasticity and tremor in a multiple sclerosis model
    • Baker D., Pryce G., Croxford J.L. Cannabinoids control spasticity and tremor in a multiple sclerosis model. Nature. 404:2000;84-87.
    • (2000) Nature , vol.404 , pp. 84-87
    • Baker, D.1    Pryce, G.2    Croxford, J.L.3
  • 7
    • 0030865871 scopus 로고    scopus 로고
    • Functional role of high-affinity anandamide transport, as revealed by selective inhibition
    • Beltramo M., Stella N., Calignano A., Lin S., Makriyannis A., Piomelli D. Functional role of high-affinity anandamide transport, as revealed by selective inhibition. Science. 277:1997;1094-1097.
    • (1997) Science , vol.277 , pp. 1094-1097
    • Beltramo, M.1    Stella, N.2    Calignano, A.3    Lin, S.4    Makriyannis, A.5    Piomelli, D.6
  • 9
    • 0029012765 scopus 로고
    • Stimulation of cannabinoid receptor CB1 induces krox-24 expression in human astrocytoma cells
    • Bouabula M.B., Bourrier B., Rinaldi-Carmona M., Shire D., LeFur G., Casellas P. Stimulation of cannabinoid receptor CB1 induces krox-24 expression in human astrocytoma cells. J Biol Chem. 270:1995;13973-13980.
    • (1995) J Biol Chem , vol.270 , pp. 13973-13980
    • Bouabula, M.B.1    Bourrier, B.2    Rinaldi-Carmona, M.3    Shire, D.4    LeFur, G.5    Casellas, P.6
  • 11
    • 0032466390 scopus 로고    scopus 로고
    • The functional neuroanatomy of brain cannabinoid receptors
    • Breivogel C.S., Childers S.R. The functional neuroanatomy of brain cannabinoid receptors. Neurobiol Dis. 5:1998;417-431.
    • (1998) Neurobiol Dis , vol.5 , pp. 417-431
    • Breivogel, C.S.1    Childers, S.R.2
  • 12
    • 0031739073 scopus 로고    scopus 로고
    • Adjuncts to dopamine replacement, a pragmatic approach to reducing the problem of dyskinesia in Parkinson's disease
    • Brotchie J.M. Adjuncts to dopamine replacement, a pragmatic approach to reducing the problem of dyskinesia in Parkinson's disease. Mot Disord. 13:1998;871-876.
    • (1998) Mot Disord , vol.13 , pp. 871-876
    • Brotchie, J.M.1
  • 13
    • 0001429144 scopus 로고    scopus 로고
    • Marijuana and the immune system
    • G.G. Nahas, K.M. Sutin, D.J. Harvey, & S. Agurell. Totowa: Humana Press
    • Cabral G.A. Marijuana and the immune system. Nahas G.G., Sutin K.M., Harvey D.J., Agurell S. Marijuana and Medicine. 1999;317-325 Humana Press, Totowa.
    • (1999) Marijuana and Medicine , pp. 317-325
    • Cabral, G.A.1
  • 14
    • 0002866783 scopus 로고
    • Marijuana decreases macrophage antiviral and antitumor activities
    • Cabral G.A., Vasquez R. Marijuana decreases macrophage antiviral and antitumor activities. Adv Biosci. 80:1991;93-105.
    • (1991) Adv Biosci , vol.80 , pp. 93-105
    • Cabral, G.A.1    Vasquez, R.2
  • 15
    • 0029889256 scopus 로고    scopus 로고
    • Biosynthesis of an endogenous cannabinoid precursor in neurons and its control by calcium and cAMP
    • Cadas H., Gaillet S., Beltramo M., Venance L., Piomelli D. Biosynthesis of an endogenous cannabinoid precursor in neurons and its control by calcium and cAMP. J Neurosci. 16:1996;3934-3942.
    • (1996) J Neurosci , vol.16 , pp. 3934-3942
    • Cadas, H.1    Gaillet, S.2    Beltramo, M.3    Venance, L.4    Piomelli, D.5
  • 16
    • 0031033841 scopus 로고    scopus 로고
    • Occurrence and biosynthesis of endogenous cannabinoid precursor, N-arachidonyl phosphatidylethanolamine, in rat brain
    • Cadas H., di Tomaso E., Piomelli D. Occurrence and biosynthesis of endogenous cannabinoid precursor, N-arachidonyl phosphatidylethanolamine, in rat brain. J Neurosci. 17:1997;1226-1242.
    • (1997) J Neurosci , vol.17 , pp. 1226-1242
    • Cadas, H.1    Di Tomaso, E.2    Piomelli, D.3
  • 17
    • 0032537734 scopus 로고    scopus 로고
    • Control of pain initiation by endogenous cannabinoids
    • Calignano A., LaRana G., Giuffrida A., Piomelli D. Control of pain initiation by endogenous cannabinoids. Nature. 394:1998;277-281.
    • (1998) Nature , vol.394 , pp. 277-281
    • Calignano, A.1    LaRana, G.2    Giuffrida, A.3    Piomelli, D.4
  • 19
    • 0031972779 scopus 로고    scopus 로고
    • Ligand binding and modulation of cyclic AMP levels depend on the chemical nature of residue 192 of the human cannabinoid receptor 1
    • Chin C.N., Lucas-Lenard J., Abadji V., Kendall D.A. Ligand binding and modulation of cyclic AMP levels depend on the chemical nature of residue 192 of the human cannabinoid receptor 1. J Neurochem. 70:1998;366-373.
    • (1998) J Neurochem , vol.70 , pp. 366-373
    • Chin, C.N.1    Lucas-Lenard, J.2    Abadji, V.3    Kendall, D.A.4
  • 20
    • 0035967179 scopus 로고    scopus 로고
    • Cannabinoids act backwards
    • Christie M.J., Vaughan C.W. Cannabinoids act backwards. Nature. 410:2001;527-530.
    • (2001) Nature , vol.410 , pp. 527-530
    • Christie, M.J.1    Vaughan, C.W.2
  • 21
    • 0032451280 scopus 로고    scopus 로고
    • Brain cannabinoid systems as targets for the therapy of neurological disorders
    • Consroe P. Brain cannabinoid systems as targets for the therapy of neurological disorders. Neurobiol Dis. 5:1998;534-551.
    • (1998) Neurobiol Dis , vol.5 , pp. 534-551
    • Consroe, P.1
  • 23
    • 0003015977 scopus 로고
    • Functional significance of cannabinoid receptors in brain
    • R.G. Pertwee. London, San Diego: Academic Press
    • Deadwyler S., Hampson R.E., Childers S.R. Functional significance of cannabinoid receptors in brain. Pertwee R.G. Cannabinoid Receptors. 1995;206-227 Academic Press, London, San Diego.
    • (1995) Cannabinoid Receptors , pp. 206-227
    • Deadwyler, S.1    Hampson, R.E.2    Childers, S.R.3
  • 24
    • 0028903996 scopus 로고
    • Anandamide amidohydrolase activity in rat brain microsomes
    • Desarnaud F., Cadas H., Piomelli D. Anandamide amidohydrolase activity in rat brain microsomes. J Biol Chem. 270:1995;6030-6035.
    • (1995) J Biol Chem , vol.270 , pp. 6030-6035
    • Desarnaud, F.1    Cadas, H.2    Piomelli, D.3
  • 25
    • 0027180394 scopus 로고
    • Enzymatic synthesis and degradation of ananadmide, a cannabinoid receptor agonist
    • Deutsch D., Chin S.A. Enzymatic synthesis and degradation of ananadmide, a cannabinoid receptor agonist. Biochem Pharmacol. 46:1993;791-796.
    • (1993) Biochem Pharmacol , vol.46 , pp. 791-796
    • Deutsch, D.1    Chin, S.A.2
  • 26
  • 30
    • 0031605955 scopus 로고    scopus 로고
    • 2-Arachidonyl-glycerol as an endocannabinoid: Limelight for a formerly neglected metabolite
    • Di Marzo V. 2-Arachidonyl-glycerol as an endocannabinoid: limelight for a formerly neglected metabolite. Biochemistry (Moscow). 63:1998;13-21.
    • (1998) Biochemistry (Moscow) , vol.63 , pp. 13-21
    • Di Marzo, V.1
  • 31
    • 0032784084 scopus 로고    scopus 로고
    • Cannabimimetic fatty acid derivatives: Anandamide family and other 'endocannabinoids'
    • Di Marzo V., Bisogno T., De Petrocellis L., Melck D., Martin B.R. Cannabimimetic fatty acid derivatives: anandamide family and other 'endocannabinoids'. Curr Med Chem. 6:1999;721-744.
    • (1999) Curr Med Chem , vol.6 , pp. 721-744
    • Di Marzo, V.1    Bisogno, T.2    De Petrocellis, L.3    Melck, D.4    Martin, B.R.5
  • 32
    • 0033567190 scopus 로고    scopus 로고
    • Biosynthesis and inactivation of the endocannabinoid 2-arachidonoylglycerol in circulating and tumoral macrophages
    • Di Marzo V., Bisogno T., De Petrocellis L., Melck D., Orlando P., Wagner J.A., Kunos G. Biosynthesis and inactivation of the endocannabinoid 2-arachidonoylglycerol in circulating and tumoral macrophages. Eur J Biochem. 264:1999;258-267.
    • (1999) Eur J Biochem , vol.264 , pp. 258-267
    • Di Marzo, V.1    Bisogno, T.2    De Petrocellis, L.3    Melck, D.4    Orlando, P.5    Wagner, J.A.6    Kunos, G.7
  • 36
    • 0034613209 scopus 로고    scopus 로고
    • 2-Arachidonylglycerol, an endogenous cannabinoid, inhibits tumor necrosis factor-α production in murine macrophages, and in mice
    • Gallily R., Breuer A., Mechoulam R. 2-Arachidonylglycerol, an endogenous cannabinoid, inhibits tumor necrosis factor-α production in murine macrophages, and in mice. Eur J Pharmacol. 406:2000;R5-R7.
    • (2000) Eur J Pharmacol , vol.406
    • Gallily, R.1    Breuer, A.2    Mechoulam, R.3
  • 37
    • 0032461050 scopus 로고    scopus 로고
    • Cannabinoid transmission and reward-related events
    • Gardner E.L., Vorel R. Cannabinoid transmission and reward-related events. Neurobiol Dis. 5:1998;501-533.
    • (1998) Neurobiol Dis , vol.5 , pp. 501-533
    • Gardner, E.L.1    Vorel, R.2
  • 39
    • 0025878961 scopus 로고
    • Molecular cloning of a human cannabinoid receptor which is also expressed in testis
    • Gerard C.M., Molerau C., Vassart G., Parmentier M. Molecular cloning of a human cannabinoid receptor which is also expressed in testis. Biochem J. 279:1991;129-134.
    • (1991) Biochem J , vol.279 , pp. 129-134
    • Gerard, C.M.1    Molerau, C.2    Vassart, G.3    Parmentier, M.4
  • 41
    • 0027527324 scopus 로고
    • Loss of cannabinoid receptors in the substantia nigra in Huntington's disease
    • Glass M., Faull R.L.M., Dregnow M. Loss of cannabinoid receptors in the substantia nigra in Huntington's disease. Neuroscience. 56:1993;523-527.
    • (1993) Neuroscience , vol.56 , pp. 523-527
    • Glass, M.1    Faull, R.L.M.2    Dregnow, M.3
  • 42
    • 0032898720 scopus 로고    scopus 로고
    • Enzymes of porcine brain hydrolyzing 2-arachidonoylglycerol, an endogenous ligand of cannabinoid receptors
    • Goparaju S.K., Ueda N., Taniguchi K., Yamamoto S. Enzymes of porcine brain hydrolyzing 2-arachidonoylglycerol, an endogenous ligand of cannabinoid receptors. Biochem Pharmacol. 57:1999;417-423.
    • (1999) Biochem Pharmacol , vol.57 , pp. 417-423
    • Goparaju, S.K.1    Ueda, N.2    Taniguchi, K.3    Yamamoto, S.4
  • 43
    • 0034944559 scopus 로고    scopus 로고
    • Stereochemical selectivity of methanandamides for the CB1 and CB2 cannabinoid receptors and their metabolic stability
    • Goutopoulos A., Fan P., Khanolkar A.D., Xie X.Q., Lin S.Y., Makriyannis A. Stereochemical selectivity of methanandamides for the CB1 and CB2 cannabinoid receptors and their metabolic stability. Bioorg Med Chem. 9:2001;1673-1684.
    • (2001) Bioorg Med Chem , vol.9 , pp. 1673-1684
    • Goutopoulos, A.1    Fan, P.2    Khanolkar, A.D.3    Xie, X.Q.4    Lin, S.Y.5    Makriyannis, A.6
  • 44
    • 0002647518 scopus 로고    scopus 로고
    • Marijuana and intraocular pressure
    • G.G. Nahas, K.M. Sutin, D.J. Harvey, & S. Agurell. Totowa: Humana Press
    • Green K. Marijuana and intraocular pressure. Nahas G.G., Sutin K.M., Harvey D.J., Agurell S. Marijuana and Medicine. 1999;581-589 Humana Press, Totowa.
    • (1999) Marijuana and Medicine , pp. 581-589
    • Green, K.1
  • 45
    • 0032467776 scopus 로고    scopus 로고
    • Role of cannabinoid receptors in memory storage
    • Hampson R.E., Deadwyler S.A. Role of cannabinoid receptors in memory storage. Neurobiol Dis. 5:1998;474-482.
    • (1998) Neurobiol Dis , vol.5 , pp. 474-482
    • Hampson, R.E.1    Deadwyler, S.A.2
  • 46
    • 0033538441 scopus 로고    scopus 로고
    • Cannabinoids, hippocampal function and memory
    • Hampson R.E., Deadwyler S.A. Cannabinoids, hippocampal function and memory. Life Sci. 65:1999;715-723.
    • (1999) Life Sci , vol.65 , pp. 715-723
    • Hampson, R.E.1    Deadwyler, S.A.2
  • 47
    • 0027489995 scopus 로고
    • Two new unsaturated fatty acid ethanolamides in brain that bind to the cannabinoid receptor
    • Hanus L., Gopher A., Almog S., Mechoulam R. Two new unsaturated fatty acid ethanolamides in brain that bind to the cannabinoid receptor. J Med Chem. 36:1993;3032-3034.
    • (1993) J Med Chem , vol.36 , pp. 3032-3034
    • Hanus, L.1    Gopher, A.2    Almog, S.3    Mechoulam, R.4
  • 50
    • 0031443586 scopus 로고    scopus 로고
    • Biochemistry and pharmacology of arachidonylethanolamide, a putative endogenous cannabinoid
    • Hillard C.J., Cambell W.B. Biochemistry and pharmacology of arachidonylethanolamide, a putative endogenous cannabinoid. J Lipid Res. 38:1997;2383-2398.
    • (1997) J Lipid Res , vol.38 , pp. 2383-2398
    • Hillard, C.J.1    Cambell, W.B.2
  • 51
    • 0031697763 scopus 로고    scopus 로고
    • Differential receptor-G-protein coupling evoked by dissimilar cannabinoid receptor agonists
    • Houston D., Howlett A.C. Differential receptor-G-protein coupling evoked by dissimilar cannabinoid receptor agonists. Cell Signal. 10:1998;667-674.
    • (1998) Cell Signal , vol.10 , pp. 667-674
    • Houston, D.1    Howlett, A.C.2
  • 52
    • 0032216738 scopus 로고    scopus 로고
    • The CB1 cannabinoid receptor in the brain
    • Howlett A.C. The CB1 cannabinoid receptor in the brain. Neurob Dis. 5:1998;405-416.
    • (1998) Neurob Dis , vol.5 , pp. 405-416
    • Howlett, A.C.1
  • 58
    • 0001535921 scopus 로고
    • The discovery of nonclassical cannabinoid analgesics
    • R. Mechoulam. Boca Raton: CRC Press
    • Johnson M.R., Melvin L.S. The discovery of nonclassical cannabinoid analgesics. Mechoulam R. Cannabinoids as Therapeutic Agents. 1986;121-145 CRC Press, Boca Raton.
    • (1986) Cannabinoids as Therapeutic Agents , pp. 121-145
    • Johnson, M.R.1    Melvin, L.S.2
  • 59
    • 0027998221 scopus 로고
    • Suppression of the humoral immune response by cannabinoids is partially mediated through inhibition of adenylate cyclase by a pertussis toxin-sensitive G-protein coupled mechanism
    • Kaminski N.E., Koh W.S., Yang K.H., Lee M., Kessler F.K. Suppression of the humoral immune response by cannabinoids is partially mediated through inhibition of adenylate cyclase by a pertussis toxin-sensitive G-protein coupled mechanism. Biochem Pharmacol. 48:1994;1899-1908.
    • (1994) Biochem Pharmacol , vol.48 , pp. 1899-1908
    • Kaminski, N.E.1    Koh, W.S.2    Yang, K.H.3    Lee, M.4    Kessler, F.K.5
  • 61
    • 0035142565 scopus 로고    scopus 로고
    • Synergistic effects of opioid and cannabinoid antagonists on food uptake
    • Kirkham T.C., Williams M. Synergistic effects of opioid and cannabinoid antagonists on food uptake. Psychopharmacology (Berlin). 153:2001;267-270.
    • (2001) Psychopharmacology (Berlin) , vol.153 , pp. 267-270
    • Kirkham, T.C.1    Williams, M.2
  • 62
    • 0035053627 scopus 로고    scopus 로고
    • Retrograde inhibition of presynaptic calcium influx by endogenous cannabinoids at excitatory synapses onto Purkinje cells
    • Kreitzer A.C., Regehr W.G. Retrograde inhibition of presynaptic calcium influx by endogenous cannabinoids at excitatory synapses onto Purkinje cells. Neuron. 29:2001;717-727.
    • (2001) Neuron , vol.29 , pp. 717-727
    • Kreitzer, A.C.1    Regehr, W.G.2
  • 63
    • 0034961493 scopus 로고    scopus 로고
    • Effects of topical anandamide-transport inhibitors, AM404 and olvanil, on intraocular pressure in normotensive rabbits
    • Laine K., Jarvinen T., Savinainen J., Laitinen J.T., Pate D.W., Jarvinen K. Effects of topical anandamide-transport inhibitors, AM404 and olvanil, on intraocular pressure in normotensive rabbits. Pharm Res. 18:2001;494-499.
    • (2001) Pharm Res , vol.18 , pp. 494-499
    • Laine, K.1    Jarvinen, T.2    Savinainen, J.3    Laitinen, J.T.4    Pate, D.W.5    Jarvinen, K.6
  • 65
    • 0002817950 scopus 로고
    • Cannabinoids as antiemetics in cancer chemotherapy
    • R. Mechoulam. Boca Raton: CRC Press
    • Levitt M. Cannabinoids as antiemetics in cancer chemotherapy. Mechoulam R. Cannabinoids as Therapeutic Agents. 1986;71-83 CRC Press, Boca Raton.
    • (1986) Cannabinoids as Therapeutic Agents , pp. 71-83
    • Levitt, M.1
  • 66
    • 0034666557 scopus 로고    scopus 로고
    • SR 141716A enhances spatial memory as assessed in a radial-arm maze task in rats
    • Lichtman A.H. SR 141716A enhances spatial memory as assessed in a radial-arm maze task in rats. Eur J Pharmacol. 404:2000;175-179.
    • (2000) Eur J Pharmacol , vol.404 , pp. 175-179
    • Lichtman, A.H.1
  • 68
    • 0034655926 scopus 로고    scopus 로고
    • Relation between decreased anandamide hydrolase concentrations in human lymphocytes and miscarriage
    • Maccarone M., Valensise H., Bari M., Lazzarin N., Romanini C., Finazzi-Agrò A. Relation between decreased anandamide hydrolase concentrations in human lymphocytes and miscarriage. Lancet. 355:2000;1326-1329.
    • (2000) Lancet , vol.355 , pp. 1326-1329
    • Maccarone, M.1    Valensise, H.2    Bari, M.3    Lazzarin, N.4    Romanini, C.5    Finazzi-Agrò, A.6
  • 69
    • 0026603679 scopus 로고
    • Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells
    • Mackie K., Hille B. Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells. Proc Natl Acad Sci USA. 89:1992;3825-3829.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 3825-3829
    • Mackie, K.1    Hille, B.2
  • 70
    • 0025600887 scopus 로고
    • The molecular basis of cannabinoid activity
    • Makriyannis A., Rapaka R.S. The molecular basis of cannabinoid activity. Life Sci. 24:1990;2173-2184.
    • (1990) Life Sci , vol.24 , pp. 2173-2184
    • Makriyannis, A.1    Rapaka, R.S.2
  • 74
    • 0032459476 scopus 로고    scopus 로고
    • Cannabinoid transmission and pain perception
    • Martin B., Lichtman A.H. Cannabinoid transmission and pain perception. Neurobiol Dis. 5:1998;447-461.
    • (1998) Neurobiol Dis , vol.5 , pp. 447-461
    • Martin, B.1    Lichtman, A.H.2
  • 75
    • 0033538561 scopus 로고    scopus 로고
    • Discovery and characterization of endogenous cannabinoids
    • Martin B.R., Mechoulam R., Razdan R.K. Discovery and characterization of endogenous cannabinoids. Life Sci. 65:1999;573-595.
    • (1999) Life Sci , vol.65 , pp. 573-595
    • Martin, B.R.1    Mechoulam, R.2    Razdan, R.K.3
  • 76
    • 0025325535 scopus 로고
    • Structure of a cannabinoid receptor and functional expression of the cloned cDNA
    • Matsuda L.A., Lolait S.J., Brownstein M.J., Young A.C., Bonner T.I. Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature. 346:1990;561-564.
    • (1990) Nature , vol.346 , pp. 561-564
    • Matsuda, L.A.1    Lolait, S.J.2    Brownstein, M.J.3    Young, A.C.4    Bonner, T.I.5
  • 77
    • 0002828258 scopus 로고
    • The unpaved road to the endogenous brain cannabinoid ligands, the anandamides
    • R.G. Pertwee. London, San Diego: Academic Press
    • Mechoulam R., Feigenbaum E. The unpaved road to the endogenous brain cannabinoid ligands, the anandamides. Pertwee R.G. Cannabinoid Receptors. 1995;233-258 Academic Press, London, San Diego.
    • (1995) Cannabinoid Receptors , pp. 233-258
    • Mechoulam, R.1    Feigenbaum, E.2
  • 78
    • 33947489961 scopus 로고
    • Isolation, structure and partial synthesis of an active constituent of hashish
    • Mechoulam R., Gaoni Y. Isolation, structure and partial synthesis of an active constituent of hashish. J Am Chem Soc. 86:1967;1646-1647.
    • (1967) J Am Chem Soc , vol.86 , pp. 1646-1647
    • Mechoulam, R.1    Gaoni, Y.2
  • 80
    • 0003895305 scopus 로고    scopus 로고
    • Cannabinoid geometry and biological activity
    • G.G. Nahas, K.M. Sutin, D.J. Harvey, & S. Agurell. Totowa: Humana Press
    • Mechoulam R., Devane W.A., Glaser R. Cannabinoid geometry and biological activity. Nahas G.G., Sutin K.M., Harvey D.J., Agurell S. Marijuana and Medicine. 1999;65-90 Humana Press, Totowa.
    • (1999) Marijuana and Medicine , pp. 65-90
    • Mechoulam, R.1    Devane, W.A.2    Glaser, R.3
  • 82
    • 0031649545 scopus 로고    scopus 로고
    • Cannabinoids: Possible role in the patho-physiology and therapy of Gilles de la Tourette syndrome
    • Muller-Vahl K.R., Kolbe H., Schneider U., Emrich H.M. Cannabinoids: possible role in the patho-physiology and therapy of Gilles de la Tourette syndrome. Acta Psychiatr Scand. 98:1998;502-506.
    • (1998) Acta Psychiatr Scand , vol.98 , pp. 502-506
    • Muller-Vahl, K.R.1    Kolbe, H.2    Schneider, U.3    Emrich, H.M.4
  • 83
    • 0027515373 scopus 로고
    • Molecular characterization of a peripheral receptor for cannabinoids
    • Munro S., Thomas K.L., Abu-Shaar M. Molecular characterization of a peripheral receptor for cannabinoids. Nature. 365:1993;61-65.
    • (1993) Nature , vol.365 , pp. 61-65
    • Munro, S.1    Thomas, K.L.2    Abu-Shaar, M.3
  • 84
    • 0344938184 scopus 로고    scopus 로고
    • Function of cannabinoid receptors in the neuroendocrine regulation of hormone secretion
    • Murphy L.L., Munoz R.M., Adrian B.A., Villnua M.A. Function of cannabinoid receptors in the neuroendocrine regulation of hormone secretion. Neurobiol Dis. 5:1998;432-446.
    • (1998) Neurobiol Dis , vol.5 , pp. 432-446
    • Murphy, L.L.1    Munoz, R.M.2    Adrian, B.A.3    Villnua, M.A.4
  • 86
    • 0003895305 scopus 로고    scopus 로고
    • G.G. Nahas, K.M. Sutin, D.J. Harvey, & S. Agurell. Totowa: Humana Press
    • Nahas G.G., Sutin K.M., Harvey D.J., Agurell S. Marijuana and Medicine. 1999;Humana Press, Totowa.
    • (1999) Marijuana and Medicine
  • 87
    • 0023896804 scopus 로고
    • Myelin basic protein is an endogenous inhibitor of the high affinity cannabinoid binding site in brain
    • Nye J.S., Voglmaier S., Martenson R.E., Snyder S.H. Myelin basic protein is an endogenous inhibitor of the high affinity cannabinoid binding site in brain. J Neurochem. 50:1988;1170-1178.
    • (1988) J Neurochem , vol.50 , pp. 1170-1178
    • Nye, J.S.1    Voglmaier, S.2    Martenson, R.E.3    Snyder, S.H.4
  • 88
    • 0035050883 scopus 로고    scopus 로고
    • Endogenous cannabinoids mediate retrograde signals from depolarized postsynaptic neurons to presynaptic terminals
    • Ohno-Shosaku T., Maejima T., Kano M. Endogenous cannabinoids mediate retrograde signals from depolarized postsynaptic neurons to presynaptic terminals. Neuron. 29:2001;729-738.
    • (2001) Neuron , vol.29 , pp. 729-738
    • Ohno-Shosaku, T.1    Maejima, T.2    Kano, M.3
  • 90
    • 0033671023 scopus 로고    scopus 로고
    • Ligand-receptor signaling with endocannabinoids in preimplantation embryo development and implantation
    • Paria B.C., Dey S.K. Ligand-receptor signaling with endocannabinoids in preimplantation embryo development and implantation. Chem Phys Lipids. 108:2000;211-220.
    • (2000) Chem Phys Lipids , vol.108 , pp. 211-220
    • Paria, B.C.1    Dey, S.K.2
  • 91
    • 0028785877 scopus 로고
    • The preimplantation embryo is a target for cannabinoid ligand-receptor signaling
    • Paria B.C., Das S.K., Dey S.K. The preimplantation embryo is a target for cannabinoid ligand-receptor signaling. Proc Natl Acad Sci USA. 92:1995;9460-9464.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 9460-9464
    • Paria, B.C.1    Das, S.K.2    Dey, S.K.3
  • 92
    • 0016416351 scopus 로고
    • Pharmacology of marijuana
    • Paton W.D.M. Pharmacology of marijuana. Annu Rev Pharmacol. 15:1975;191-220.
    • (1975) Annu Rev Pharmacol , vol.15 , pp. 191-220
    • Paton, W.D.M.1
  • 93
    • 0001918779 scopus 로고
    • Pharmacological, physiological and clinical implications of the discovery of cannabinoid receptors
    • R.G. Pertwee. London, San Diego: Academic Press
    • Pertwee R.G. Pharmacological, physiological and clinical implications of the discovery of cannabinoid receptors. Pertwee R.G. Cannabinoid Receptors. 1995;69-83 Academic Press, London, San Diego.
    • (1995) Cannabinoid Receptors , pp. 69-83
    • Pertwee, R.G.1
  • 94
    • 0030611978 scopus 로고    scopus 로고
    • Pharmacology of cannabinoid CB1 and CB2 receptors
    • Pertwee R.G. Pharmacology of cannabinoid CB1 and CB2 receptors. Pharmacol Ther. 74:1997;129-180.
    • (1997) Pharmacol Ther , vol.74 , pp. 129-180
    • Pertwee, R.G.1
  • 95
    • 0033921628 scopus 로고    scopus 로고
    • Cannabinoid receptor ligands: Clinical and neuropharmacological considerations, relevant to future drug discovery and development
    • Pertwee R.G. Cannabinoid receptor ligands: clinical and neuropharmacological considerations, relevant to future drug discovery and development. Expert Opin Invest Drugs. 9:2000;1-19.
    • (2000) Expert Opin Invest Drugs , vol.9 , pp. 1-19
    • Pertwee, R.G.1
  • 96
    • 0028226120 scopus 로고
    • Effects of two endogenous fatty acid ethanolamides on mouse vasa deferentia
    • Pertwee R.G., Griffin G., Hanus L., Mechoulam R. Effects of two endogenous fatty acid ethanolamides on mouse vasa deferentia. Eur J Pharmacol. 259:1994;115-120.
    • (1994) Eur J Pharmacol , vol.259 , pp. 115-120
    • Pertwee, R.G.1    Griffin, G.2    Hanus, L.3    Mechoulam, R.4
  • 97
    • 0028924860 scopus 로고
    • Effect of phenylmethylsulphonylfluoride on the potency of anandamide as an inhibitor of electrically evoked contractions in two isolated tissue preparations
    • Pertwee R.G., Fernardo S.R., Griffin G., Abadji V., Makriyannis A. Effect of phenylmethylsulphonylfluoride on the potency of anandamide as an inhibitor of electrically evoked contractions in two isolated tissue preparations. Eur J Pharmacol. 272:1995;73-78.
    • (1995) Eur J Pharmacol , vol.272 , pp. 73-78
    • Pertwee, R.G.1    Fernardo, S.R.2    Griffin, G.3    Abadji, V.4    Makriyannis, A.5
  • 101
    • 0022885592 scopus 로고
    • Structure-activity relationships in cannabinoids
    • Razdan R.K. Structure-activity relationships in cannabinoids. Pharmacol Rev. 38:1986;75-134.
    • (1986) Pharmacol Rev , vol.38 , pp. 75-134
    • Razdan, R.K.1
  • 103
    • 0033538482 scopus 로고    scopus 로고
    • Motor actions of cannabinoids in the basal ganglia output nuclei
    • Sañudo-Peña M.C., Tsou K., Walker M. Motor actions of cannabinoids in the basal ganglia output nuclei. Life Sci. 65:1999;703-713.
    • (1999) Life Sci , vol.65 , pp. 703-713
    • Sañudo-Peña, M.C.1    Tsou, K.2    Walker, M.3
  • 104
    • 0030937829 scopus 로고    scopus 로고
    • Changes in anandamide levels in mouse uterus are associated with uterine receptivity for embryo implantation
    • Schmid P., Paria B.C., Krebsbach R., Schmid H., Dey S.K. Changes in anandamide levels in mouse uterus are associated with uterine receptivity for embryo implantation. Proc Natl Acad Sci USA. 94:1997;4188-4192.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 4188-4192
    • Schmid, P.1    Paria, B.C.2    Krebsbach, R.3    Schmid, H.4    Dey, S.K.5
  • 108
    • 0030870722 scopus 로고    scopus 로고
    • A second endogenous cannabinoid that modulates long-term potentiation
    • Stella N., Schweitzer P., Piomelli D. A second endogenous cannabinoid that modulates long-term potentiation. Nature. 388:1997;773-778.
    • (1997) Nature , vol.388 , pp. 773-778
    • Stella, N.1    Schweitzer, P.2    Piomelli, D.3
  • 109
    • 0015691532 scopus 로고
    • Single-dose effect of marijuana smoke: Bronchial dynamics and respiratory-center sensitivity in normal subjects
    • Vachon L., Fitzerald M.X., Solliday N.H., Gould I.A., Gaensler E.A. Single-dose effect of marijuana smoke: bronchial dynamics and respiratory-center sensitivity in normal subjects. N Engl J Med. 288:1973;985-989.
    • (1973) N Engl J Med , vol.288 , pp. 985-989
    • Vachon, L.1    Fitzerald, M.X.2    Solliday, N.H.3    Gould, I.A.4    Gaensler, E.A.5
  • 111
    • 0032982520 scopus 로고    scopus 로고
    • The central cannabinoid receptor (CB1) mediates inhibition of nitric oxide production by rat microglial cells
    • Waksman Y., Olson S.M., Carlisle S.J., Cabral G.A. The central cannabinoid receptor (CB1) mediates inhibition of nitric oxide production by rat microglial cells. J Pharmacol Exp Ther. 288:1999;1357-1366.
    • (1999) J Pharmacol Exp Ther , vol.288 , pp. 1357-1366
    • Waksman, Y.1    Olson, S.M.2    Carlisle, S.J.3    Cabral, G.A.4
  • 113
    • 0005116609 scopus 로고    scopus 로고
    • Anandamide induces overeating: Mediation by central cannabinoid (CB1) receptors
    • Williams M., Kirkham T.C. Anandamide induces overeating: mediation by central cannabinoid (CB1) receptors. Psychopharmacology (Berlin). 153:1999;267-270.
    • (1999) Psychopharmacology (Berlin) , vol.153 , pp. 267-270
    • Williams, M.1    Kirkham, T.C.2
  • 114
    • 0035967145 scopus 로고    scopus 로고
    • Endogenous cannabinoids mediate retrograde signaling at hippocampal synapses
    • Wilson R.I., Nicoll R.A. Endogenous cannabinoids mediate retrograde signaling at hippocampal synapses. Nature. 410:2001;588-592.
    • (2001) Nature , vol.410 , pp. 588-592
    • Wilson, R.I.1    Nicoll, R.A.2
  • 115
    • 0029064111 scopus 로고
    • Common cannabimimetic pharmacophoric requirements between aminoalkylindoles and classical cannabinoids
    • Xie X.-Q., Eissentat M., Makriyannis A. Common cannabimimetic pharmacophoric requirements between aminoalkylindoles and classical cannabinoids. Life Sci. 56:1995;1963-1970.
    • (1995) Life Sci , vol.56 , pp. 1963-1970
    • Xie, X.-Q.1    Eissentat, M.2    Makriyannis, A.3
  • 117
    • 0005159154 scopus 로고    scopus 로고
    • Effects of cannabinoids on spermatogenesis in mice
    • G.G. Nahas, K.M. Sutin, D.J. Harvey, & S. Agurell. Totowa: Humana Press
    • Zimmerman M.A., Zimmerman S., Raj A.Y. Effects of cannabinoids on spermatogenesis in mice. Nahas G.G., Sutin K.M., Harvey D.J., Agurell S. Marijuana and Medicine. 1999;347-358 Humana Press, Totowa.
    • (1999) Marijuana and Medicine , pp. 347-358
    • Zimmerman, M.A.1    Zimmerman, S.2    Raj, A.Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.