Finite element analysis of pharmaceutical tablet compaction using a density dependent material plasticity model

Powder Technology

Volumn 202, Issue 1-3, 2010, Pages 46-54

  Sinha, Tuhin ^a   Bharadwaj, Rahul ^b   Curtis, Jennifer S ^c   Hancock, Bruno C ^b   Wassgren, Carl ^a,d  

^a PURDUE UNIVERSITY   (United States)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

^c J Crayton Pruitt Family Department of Biomedical Engineering   (United States)

^d PURDUE UNIVERSITY   (United States)

Author keywords

Constitutive model; Drucker Prager Cap; Finite element method; Powder; Relative density; Tablet compaction

Indexed keywords

A-DENSITY; DRUCKER-PRAGER; DRUCKER-PRAGER CAP; DRUCKER-PRAGER CAP MODELS; EXPERIMENTAL MEASUREMENTS; FEM SIMULATIONS; FINITE ELEMENT ANALYSIS; FINITE ELEMENT METHOD SIMULATION; MATERIAL PROPERTY; PHARMACEUTICAL TABLETS; PLASTICITY MODEL; PROPERTY MODELS; RELATIVE DENSITY; SOLID FRACTION; SURFACE HARDNESS; TABLET COMPACTION;

COMPACTION; COMPUTER SIMULATION; CONSTITUTIVE MODELS; DRUG PRODUCTS; MATERIALS PROPERTIES;

FINITE ELEMENT METHOD;

DRUG;

ARTICLE; FINITE ELEMENT ANALYSIS; MATERIALS TESTING; PREDICTION; RELATIVE DENSITY; SIMULATION; SURFACE PROPERTY; TABLET COMPRESSION; TABLET HARDNESS;

EID: 77953612078     PISSN: 00325910     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.powtec.2010.04.001     Document Type: Article

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