Numerical and experimental investigation of capping mechanisms during pharmaceutical tablet compaction

Powder Technology

Volumn 181, Issue 2, 2008, Pages 121-129

  Wu, C Y ^a   Hancock, B C ^b   Mills, A ^c   Bentham, A C ^c   Best, S M ^a   Elliott, J A ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

^c PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

Author keywords

Capping; Failure mechanisms; Finite element modelling; Powder compaction; Tablet; X ray tomography

Indexed keywords

COMPACTION; COMPUTER SIMULATION; NUMERICAL METHODS; TENSILE STRENGTH;

CAPPING; FAILURE MECHANISMS; FINITE ELEMENT MODELING; POWDER COMPACTION; X-RAY TOMOGRAPHY;

DRUG PRODUCTS;

LACTOSE;

COMPACTION; COMPUTER SIMULATION; DRUG PRODUCTS; NUMERICAL METHODS; TENSILE STRENGTH;

ARTICLE; FINITE ELEMENT ANALYSIS; FRICTION; LUBRICATION; POWDER; SCANNING ELECTRON MICROSCOPE; SHEAR STRESS; SURFACE PROPERTY; TABLET COMPRESSION; TABLET THICKNESS; TENSILE STRENGTH; X RAY MICROANALYSIS;

EID: 38149005462     PISSN: 00325910     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.powtec.2006.12.017     Document Type: Article

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