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Volumn 12, Issue 12, 2010, Pages 2810-2813

Metalated nitrile and enolate chlorinations

Author keywords

[No Author keywords available]

Indexed keywords


EID: 77953584940     PISSN: 15237060     EISSN: 15237052     Source Type: Journal    
DOI: 10.1021/ol100897y     Document Type: Article
Times cited : (11)

References (64)
  • 11
    • 77953579540 scopus 로고    scopus 로고
    • For reviews see
    • For reviews see
  • 14
    • 77953556914 scopus 로고    scopus 로고
    • Halonitriles are also generated by halogenating cyanohydrins
    • Halonitriles are also generated by halogenating cyanohydrins
  • 26
    • 77953547855 scopus 로고    scopus 로고
    • Sequential silylketenimine formation and iodination is currently the most general route to iodonitriles but is limited to arylacetonitriles
    • Sequential silylketenimine formation and iodination is currently the most general route to iodonitriles but is limited to arylacetonitriles
  • 29
    • 77953579875 scopus 로고    scopus 로고
    • Commercially available from SynQuest Fluorochemicals
    • Commercially available from SynQuest Fluorochemicals.
  • 30
    • 77953549848 scopus 로고    scopus 로고
    • In an extensive screening of halogenating agents no electrophilic halogen source was as effective as 2-chloro-2-fluoro-2-phenylacetonitrile (6)
    • In an extensive screening of halogenating agents no electrophilic halogen source was as effective as 2-chloro-2-fluoro-2-phenylacetonitrile (6).
  • 34
    • 77953606241 scopus 로고    scopus 로고
    • The conversion with secondary nitriles is low and considerable dimerization is observed. A similar limitation exists for the iodination of aldehyde enolates
    • The conversion with secondary nitriles is low and considerable dimerization is observed. A similar limitation exists for the iodination of aldehyde enolates
  • 39
    • 77953571548 scopus 로고    scopus 로고
    • For related halogenating agents, see
    • For related halogenating agents, see
  • 44
    • 77953574526 scopus 로고    scopus 로고
    • Spectrally indistinguishable to previously reported material
    • Spectrally indistinguishable to previously reported material
  • 49
    • 77953558184 scopus 로고    scopus 로고
    • The chloronitrile 8a requires room temperature, whereas the corresponding bromonitrile exchanges with i -PrMgCl virtually instantaneously at - 78 °C. (3)
    • The chloronitrile 8a requires room temperature, whereas the corresponding bromonitrile exchanges with i -PrMgCl virtually instantaneously at - 78 °C. (3)
  • 60
    • 77953605927 scopus 로고    scopus 로고
    • For examples involving transition metals, see
    • For examples involving transition metals, see


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.