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77953547855
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Sequential silylketenimine formation and iodination is currently the most general route to iodonitriles but is limited to arylacetonitriles
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Sequential silylketenimine formation and iodination is currently the most general route to iodonitriles but is limited to arylacetonitriles
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Commercially available from SynQuest Fluorochemicals
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Commercially available from SynQuest Fluorochemicals.
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30
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77953549848
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In an extensive screening of halogenating agents no electrophilic halogen source was as effective as 2-chloro-2-fluoro-2-phenylacetonitrile (6)
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In an extensive screening of halogenating agents no electrophilic halogen source was as effective as 2-chloro-2-fluoro-2-phenylacetonitrile (6).
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77953606241
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The conversion with secondary nitriles is low and considerable dimerization is observed. A similar limitation exists for the iodination of aldehyde enolates
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The conversion with secondary nitriles is low and considerable dimerization is observed. A similar limitation exists for the iodination of aldehyde enolates
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77953571548
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77953574526
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Spectrally indistinguishable to previously reported material
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Spectrally indistinguishable to previously reported material
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45
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The chloronitrile 8a requires room temperature, whereas the corresponding bromonitrile exchanges with i -PrMgCl virtually instantaneously at - 78 °C. (3)
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The chloronitrile 8a requires room temperature, whereas the corresponding bromonitrile exchanges with i -PrMgCl virtually instantaneously at - 78 °C. (3)
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