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Volumn 15, Issue 1, 2010, Pages 76-85

Pancreatic islet PEGylation as an immunological polymeric restraint

Author keywords

Diabetes mellitus; Immunoprotection; Pancreatic islet; PEGylation; Transplantation

Indexed keywords

DIABETES MELLITUS; IMMUNE TOLERANCES; IMMUNO-ISOLATION; IMMUNOGENICITY; IMMUNOPROTECTION; PANCREATIC ISLET; PEGYLATION; SYNERGISTIC EFFECT; TYPE 1 DIABETES MELLITUS;

EID: 77953583276     PISSN: 12268372     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12257-009-3063-7     Document Type: Review
Times cited : (9)

References (75)
  • 1
    • 2542471878 scopus 로고    scopus 로고
    • Diabetes complications
    • Bloomgarden, Z. T. (2004) Diabetes complications. Diabetes Care 27: 1506-1514.
    • (2004) Diabetes Care , vol.27 , pp. 1506-1514
    • Bloomgarden, Z.T.1
  • 2
    • 7044241096 scopus 로고    scopus 로고
    • Identifying and managing the complications of diabetes
    • Hill, J. (2004) Identifying and managing the complications of diabetes. Nurs. Times 100: 40-44.
    • (2004) Nurs. Times , vol.100 , pp. 40-44
    • Hill, J.1
  • 3
    • 1842731851 scopus 로고    scopus 로고
    • Clinical islet transplantation: Advances and immunological challenges
    • Ricordi, C. and T. B. Strom (2004) Clinical islet transplantation: advances and immunological challenges. Nat. Rev. Immunol. 4: 259-268.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 259-268
    • Ricordi, C.1    Strom, T.B.2
  • 4
    • 0344984343 scopus 로고    scopus 로고
    • Clinical islet transplant: Current and future directions towards tolerance
    • Shapiro, A. M. J., S. A. Nanji, and J. R. Lakey (2003) Clinical islet transplant: current and future directions towards tolerance. Immunol. Rev. 196: 219-236.
    • (2003) Immunol. Rev. , vol.196 , pp. 219-236
    • Shapiro, A.M.J.1    Nanji, S.A.2    Lakey, J.R.3
  • 5
    • 0035752662 scopus 로고    scopus 로고
    • Diabetes. Islet cell transplantation
    • Shapiro, A. M. J., E. A. Ryan, and J. R. Lakey (2001) Diabetes. Islet cell transplantation. Lancet 358: 21.
    • (2001) Lancet , vol.358 , pp. 21
    • Shapiro, A.M.J.1    Ryan, E.A.2    Lakey, J.R.3
  • 6
    • 0035084212 scopus 로고    scopus 로고
    • Current limitation of islet transplantation
    • Mathieu, C. (2001) Current limitation of islet transplantation. Transplantation proceedings 33: 1707-1708.
    • (2001) Transplantation Proceedings , vol.33 , pp. 1707-1708
    • Mathieu, C.1
  • 8
    • 0026512194 scopus 로고
    • Microencapsulated islet grafts in the BB/E rat: A possible role for cytokines in graft failure
    • Cole, D. R., M. Waterfall, M. McIntyre, and J. D. Baird (1992) Microencapsulated islet grafts in the BB/E rat: a possible role for cytokines in graft failure. Diabetologia 35: 231-237.
    • (1992) Diabetologia , vol.35 , pp. 231-237
    • Cole, D.R.1    Waterfall, M.2    McIntyre, M.3    Baird, J.D.4
  • 9
    • 0023779707 scopus 로고
    • Destruction of rat islet cell monolayers by cytokines. Synergistic interactions of interferon-gamma, tumor necrosis factor, lymphotoxin, and interleukin 1
    • Pukel, C., H. Baquerizo, and A. Rabinovitch (1988) Destruction of rat islet cell monolayers by cytokines. Synergistic interactions of interferon-gamma, tumor necrosis factor, lymphotoxin, and interleukin 1. Diabetes 37: 133-136.
    • (1988) Diabetes , vol.37 , pp. 133-136
    • Pukel, C.1    Baquerizo, H.2    Rabinovitch, A.3
  • 10
    • 0030478712 scopus 로고    scopus 로고
    • Cytotoxicity of peritoneal murine macrophages against encapsulated pancreatic rat islets: In vivo and in vitro studies
    • Kessler, L., C. Jesser, Y. Lombard, V. Karsten, A. Belcourt, M. Pinget, and P. Poindron (1996) Cytotoxicity of peritoneal murine macrophages against encapsulated pancreatic rat islets: in vivo and in vitro studies. J. Leukoc. Biol. 60: 729-736.
    • (1996) J. Leukoc. Biol. , vol.60 , pp. 729-736
    • Kessler, L.1    Jesser, C.2    Lombard, Y.3    Karsten, V.4    Belcourt, A.5    Pinget, M.6    Poindron, P.7
  • 11
    • 0025685395 scopus 로고
    • Inhibition of insulin secretion by interleukin-1 beta and tumour necrosis factor-alpha via an L-arginine-dependent nitric oxide generating mechanism
    • Southern, C., D. Schulster, and I. C. Green (1990) Inhibition of insulin secretion by interleukin-1 beta and tumour necrosis factor-alpha via an L-arginine-dependent nitric oxide generating mechanism. FEBS Lett. 276: 42-44.
    • (1990) FEBS Lett. , vol.276 , pp. 42-44
    • Southern, C.1    Schulster, D.2    Green, I.C.3
  • 12
    • 0030807633 scopus 로고    scopus 로고
    • Co-culture of pancreatic islets and allogeneic lymphocytes: Alterations of responder and stimulator cells
    • Kuttler, B., H. Wanka, and H. J. Hahn (1997) Co-culture of pancreatic islets and allogeneic lymphocytes: alterations of responder and stimulator cells. Transplantation 64: 480-489.
    • (1997) Transplantation , vol.64 , pp. 480-489
    • Kuttler, B.1    Wanka, H.2    Hahn, H.J.3
  • 14
    • 0023784346 scopus 로고
    • IFN-gamma and tumor necrosis factor-alpha. Cytotoxicity to murine islets of Langerhans
    • Campbell, I. L., A. Iscaro, and L. C. Harrison (1988) IFN-gamma and tumor necrosis factor-alpha. Cytotoxicity to murine islets of Langerhans. J. Immunol. 141: 2325-2329.
    • (1988) J. Immunol. , vol.141 , pp. 2325-2329
    • Campbell, I.L.1    Iscaro, A.2    Harrison, L.C.3
  • 15
    • 0025753951 scopus 로고
    • Activated macrophages kill pancreatic syngeneic islet cells via arginine-dependent nitric oxide generation
    • Kroncke, K. D., V. Kolb-Bachofen, B. Berschick, V. Burkart, and H. Kolb (1991) Activated macrophages kill pancreatic syngeneic islet cells via arginine-dependent nitric oxide generation. Biochem. Biophys. Res. Commun. 175: 752-758.
    • (1991) Biochem. Biophys. Res. Commun. , vol.175 , pp. 752-758
    • Kroncke, K.D.1    Kolb-Bachofen, V.2    Berschick, B.3    Burkart, V.4    Kolb, H.5
  • 16
    • 0034721255 scopus 로고    scopus 로고
    • Islet transplantation in seven patients with type i diabetes mellitus using a glucocorticoid-free immunosuppressive regimen
    • Shapiro, A. M. J., J. R. Lakey, E. A. Ryan, G. S. Korbutt, E. Toth, G. L. Warnock, N. M. Kneteman, and R. V. Rajotte (2000) Islet transplantation in seven patients with type I diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N. Engl. J. Med. 343: 230-238.
    • (2000) N. Engl. J. Med. , vol.343 , pp. 230-238
    • Shapiro, A.M.J.1    Lakey, J.R.2    Ryan, E.A.3    Korbutt, G.S.4    Toth, E.5    Warnock, G.L.6    Kneteman, N.M.7    Rajotte, R.V.8
  • 18
    • 1442265579 scopus 로고    scopus 로고
    • Islet transplantation as a treatment of diabetes - A work in progress
    • Robertson, R. P. (2004) Islet transplantation as a treatment of diabetes - a work in progress. N. Engl. J. Med. 350: 694-705.
    • (2004) N. Engl. J. Med. , vol.350 , pp. 694-705
    • Robertson, R.P.1
  • 19
    • 0027968617 scopus 로고
    • Nephrotoxicity following orthotopic liver transplantation: A comparison between cyclosporine and FK506
    • Platz, K. P., A. R. Mueller, G. Blumhardt, S. Bachmann, W. O. Bechstein, A. Kahl and P. Neuhaus (1994) Nephrotoxicity following orthotopic liver transplantation. A comparison between cyclosporine and FK506. Transplantation 58: 170-178. (Pubitemid 24236210)
    • (1994) Transplantation , vol.58 , Issue.2 , pp. 170-178
    • Platz, K.-P.1    Mueller, A.R.2    Blumhardt, G.3    Bachmann, S.4    Bechstein, W.-O.5    Kahl, A.6    Neuhaus, P.7
  • 20
    • 0030448982 scopus 로고    scopus 로고
    • Role of steroid dose in hypertension early after liver transplantation with tacrolimus (FK506) and cyclosporine
    • Taler, S. J., S. C. Textor, V. J. Canzanello, L. Schwartz, M. Porayko, R. H. Wiesner, and R. A. Krom (1996) Role of steroid dose in hypertension early after liver transplantation with tacrolimus (FK506) and cyclosporine. Transplantation 62: 1588-1592.
    • (1996) Transplantation , vol.62 , pp. 1588-1592
    • Taler, S.J.1    Textor, S.C.2    Canzanello, V.J.3    Schwartz, L.4    Porayko, M.5    Wiesner, R.H.6    Krom, R.A.7
  • 22
    • 0029758419 scopus 로고    scopus 로고
    • Microangiopathic hemolytic anemia complicating FK506 (tacrolimus) therapy
    • Mach-Pascual, S., K. Samii, and P. Beris (1996) Microangiopathic hemolytic anemia complicating FK506 (tacrolimus) therapy. Am. J. Hematol. 52: 310-312.
    • (1996) Am. J. Hematol. , vol.52 , pp. 310-312
    • MacH-Pascual, S.1    Samii, K.2    Beris, P.3
  • 24
    • 0036192342 scopus 로고    scopus 로고
    • Considerations for successful transplantation of encapsulated pancreatic islets
    • DOI 10.1007/s00125-001-0729-x
    • de Vos, P., A. F. Hamel, and K. Tatarkiewicz (2002) Considerations for successful transplantation of encapsulated pancreatic islets. Diabetologia 45: 159-173. (Pubitemid 34208378)
    • (2002) Diabetologia , vol.45 , Issue.2 , pp. 159-173
    • De Vos, P.1    Hamel, A.F.2    Tatarkiewicz, K.3
  • 25
    • 0029027755 scopus 로고
    • Xenotransplantation of porcine and bovine islets without immunosuppression using uncoated alginate microspheres
    • Lanza, R. P., W. M. Kuhtreiber, D. Ecker, J. E. Staruk, and W. L. Chick (1995) Xenotransplantation of porcine and bovine islets without immunosuppression using uncoated alginate microspheres. Transplantation 59: 1377-1384.
    • (1995) Transplantation , vol.59 , pp. 1377-1384
    • Lanza, R.P.1    Kuhtreiber, W.M.2    Ecker, D.3    Staruk, J.E.4    Chick, W.L.5
  • 27
    • 34548020945 scopus 로고    scopus 로고
    • Isletencapsulation in ultra-thin layer-by-layer membranes of poly(vinyl alcohol) anchored to poly(ethylene glycol)-lipids in the cell membrane
    • Teramura, Y., Y. Kaneda, and H. Iwata (2007) Isletencapsulation in ultra-thin layer-by-layer membranes of poly(vinyl alcohol) anchored to poly(ethylene glycol)-lipids in the cell membrane. Biomaterials 28: 4818-4825.
    • (2007) Biomaterials , vol.28 , pp. 4818-4825
    • Teramura, Y.1    Kaneda, Y.2    Iwata, H.3
  • 30
    • 3242732200 scopus 로고    scopus 로고
    • Cytoprotection of PEG-modified adult porcine pancreatic islets for improved xenotransplantation
    • Xie, D., C. A. Smyth, C. Eckstein, G. Bilbao, J. Mays, D. E. Eckhoff, and J. L. Contreras (2005) Cytoprotection of PEG-modified adult porcine pancreatic islets for improved xenotransplantation. Biomaterials 26: 403-412.
    • (2005) Biomaterials , vol.26 , pp. 403-412
    • Xie, D.1    Smyth, C.A.2    Eckstein, C.3    Bilbao, G.4    Mays, J.5    Eckhoff, D.E.6    Contreras, J.L.7
  • 31
    • 0032810120 scopus 로고    scopus 로고
    • In vitro and in vivo performance of porcine islets encapsulated in interfacially photoplolymerized poly(ethylene glycol) diacrylate membrane
    • Cruise, G. M., O. D. Hegre, F. V. Lamberti, S. R. Hager, R. Hill, D. S. Scharp, and J. A. Hubbell (1999) In vitro and in vivo performance of porcine islets encapsulated in interfacially photoplolymerized poly(ethylene glycol) diacrylate membrane. Cell Transplant 8: 293-306.
    • (1999) Cell Transplant , vol.8 , pp. 293-306
    • Cruise, G.M.1    Hegre, O.D.2    Lamberti, F.V.3    Hager, S.R.4    Hill, R.5    Scharp, D.S.6    Hubbell, J.A.7
  • 32
    • 0031593230 scopus 로고    scopus 로고
    • Immunoisolation of adult porcine islets for the treatment of diabetes mellitus. the use of photopolymerizable polyethylene glycol in the conformal coating of massisolated porcine islets
    • Hill, R. S., G. M. Cruise, S. R. Hager, F. V. Lamberti, X. Yu, C. L. Garufis, Y. Yu, K. E. Mundwiler, J. F. Cole, J. A. Hubbell, O. D. Hegre, and D. W. Scharp (1997) Immunoisolation of adult porcine islets for the treatment of diabetes mellitus. The use of photopolymerizable polyethylene glycol in the conformal coating of massisolated porcine islets. Ann. N. Y. Acad. Sci. 831: 332-343.
    • (1997) Ann. N. Y. Acad. Sci. , vol.831 , pp. 332-343
    • Hill, R.S.1    Cruise, G.M.2    Hager, S.R.3    Lamberti, F.V.4    Yu, X.5    Garufis, C.L.6    Yu, Y.7    Mundwiler, K.E.8    Cole, J.F.9    Hubbell, J.A.10    Hegre, O.D.11    Scharp, D.W.12
  • 33
    • 0032549601 scopus 로고    scopus 로고
    • Asensitivity study of the key parameters in the interfacial photopolymerization of poly(ethylene glycol) diacrylate upon porcine islets
    • Cruise, G. M., O. D. Hegre, D. S. Scharp, and J. A. Hubbell (1998) Asensitivity study of the key parameters in the interfacial photopolymerization of poly(ethylene glycol) diacrylate upon porcine islets. Biotechnol. Bioeng. 57: 655-665.
    • (1998) Biotechnol. Bioeng. , vol.57 , pp. 655-665
    • Cruise, G.M.1    Hegre, O.D.2    Scharp, D.S.3    Hubbell, J.A.4
  • 34
    • 0029007384 scopus 로고
    • Poly(ethylene glycol) with reactive end groups. I. Modification of proteins
    • Hoofman, G., S. Herman, and E. Schacht (1995) Poly(ethylene glycol) with reactive end groups: I. Modification of proteins. J. Bioact. Compat. Pol. 10: 145-187.
    • (1995) J. Bioact. Compat. Pol. , vol.10 , pp. 145-187
    • Hoofman, G.1    Herman, S.2    Schacht, E.3
  • 35
    • 0009971781 scopus 로고    scopus 로고
    • Biochemistry and immunology of poly(ethylene glycol -modified adenosine deaminase (PEG-ADA)
    • J. M. Harris and S. Zalipsky (eds.). American Chemical Society. Washington, DC, USA
    • Hershfield, M. S. (1997) Biochemistry and immunology of poly(ethylene glycol)-modified adenosine deaminase (PEG-ADA). pp 170-181. In: J. M. Harris and S. Zalipsky (eds.). Poly(ethylene glycol) chemistry and biological applications. American Chemical Society. Washington, DC, USA.
    • (1997) Poly(ethylene Glycol) Chemistry and Biological Applications , pp. 170-181
    • Hershfield, M.S.1
  • 37
    • 0033559323 scopus 로고    scopus 로고
    • Structural and functional consequences of antigenic modulation of red blood cells with methoxypoly(ethylene glycol)
    • Murad, K. L., K. L. Mahany, C. Brugnara, F. A. Kuypers, J. W. Eaton, and M. D. Scott (1999) Structural and functional consequences of antigenic modulation of red blood cells with methoxypoly(ethylene glycol). Blood 93: 2121-2127.
    • (1999) Blood , vol.93 , pp. 2121-2127
    • Murad, K.L.1    Mahany, K.L.2    Brugnara, C.3    Kuypers, F.A.4    Eaton, J.W.5    Scott, M.D.6
  • 38
    • 0033568220 scopus 로고    scopus 로고
    • Stealth cells: Prevention of major histocompatibility complex class II-mediated T-cell activation by cell surface modification
    • Murad, K. L., E. J. Gosselin, J. W. Eaton, and M. D. Scott (1999) Stealth cells: prevention of major histocompatibility complex class II-mediated T-cell activation by cell surface modification. Blood 94: 2135-2141.
    • (1999) Blood , vol.94 , pp. 2135-2141
    • Murad, K.L.1    Gosselin, E.J.2    Eaton, J.W.3    Scott, M.D.4
  • 40
    • 15244343341 scopus 로고    scopus 로고
    • Surface decoration of red blood cells with maleimidophenyl-polyethylene glycol facilitated by thiolation with iminothiolane: An approach to mask A, B, and D antigens to generate universal red blood cells
    • Nacharaju, P., F. N. Boctor, B. N. Manjula, and S. A. Acharya (2005) Surface decoration of red blood cells with maleimidophenyl-polyethylene glycol facilitated by thiolation with iminothiolane: an approach to mask A, B, and D antigens to generate universal red blood cells. Transfusion 45: 374-383.
    • (2005) Transfusion , vol.45 , pp. 374-383
    • Nacharaju, P.1    Boctor, F.N.2    Manjula, B.N.3    Acharya, S.A.4
  • 42
    • 33846595829 scopus 로고    scopus 로고
    • Functional and histological evaluation of transplanted pancreatic islets immunoprotected by PEGylation and cyclosporine for 1 year
    • Lee, D. Y., J. H. Nam, and Y. Byun (2007) Functional and histological evaluation of transplanted pancreatic islets immunoprotected by PEGylation and cyclosporine for 1 year. Biomaterials 28: 1957-1966.
    • (2007) Biomaterials , vol.28 , pp. 1957-1966
    • Lee, D.Y.1    Nam, J.H.2    Byun, Y.3
  • 43
    • 33646351744 scopus 로고    scopus 로고
    • A new strategy toward improving immunoprotection in cell therapy for diabetes mellitus: Long-functioning PEGylated islets in vitro
    • Lee, D. Y., S. J. Park, J. H. Nam, and Y. Byun (2006) A new strategy toward improving immunoprotection in cell therapy for diabetes mellitus: long-functioning PEGylated islets in vitro. Tissue Eng. 12: 615-623.
    • (2006) Tissue Eng. , vol.12 , pp. 615-623
    • Lee, D.Y.1    Park, S.J.2    Nam, J.H.3    Byun, Y.4
  • 44
    • 3142723475 scopus 로고    scopus 로고
    • Effect of polyethylene glycol grafted onto islet capsules on prevention of splenocyte and cytokine attacks
    • Lee, D. Y., J. H. Nam, and Y. Byun (2004). Effect of polyethylene glycol grafted onto islet capsules on prevention of splenocyte and cytokine attacks. J. Biomater. Sci. Polymer Edn. 15: 753-766.
    • (2004) J. Biomater. Sci. Polymer Edn. , vol.15 , pp. 753-766
    • Lee, D.Y.1    Nam, J.H.2    Byun, Y.3
  • 45
    • 0024807859 scopus 로고
    • A new phase of insulin secretion, how will it contribute to our understanding of β-cell function
    • Grodsky, G. M. (1989) A new phase of insulin secretion, how will it contribute to our understanding of β-cell function. Diabetes 38: 673-678.
    • (1989) Diabetes , vol.38 , pp. 673-678
    • Grodsky, G.M.1
  • 46
    • 33646735392 scopus 로고    scopus 로고
    • Biological and biomaterial approaches for improved islet transplantation
    • Narang, A. S. and R. I. Mahato (2006) Biological and biomaterial approaches for improved islet transplantation. Pharmacol. Rev. 58: 194-243.
    • (2006) Pharmacol. Rev. , vol.58 , pp. 194-243
    • Narang, A.S.1    Mahato, R.I.2
  • 47
    • 0030848621 scopus 로고    scopus 로고
    • Fuzzy nanoassemblies: Toward layered polymeric multicomposites
    • Decher, G. (1997) Fuzzy nanoassemblies: toward layered polymeric multicomposites. Science 277: 1232-1237.
    • (1997) Science , vol.277 , pp. 1232-1237
    • Decher, G.1
  • 48
    • 34247570124 scopus 로고    scopus 로고
    • Next generation, sequentially assembled ultrathin films: Beyond electrostatics
    • Quinn, J. F., A. P. R. Johnston, G. K. Such, A. N. Zelikin, and F. Caruso (2007) Next generation, sequentially assembled ultrathin films: beyond electrostatics. Chem. Soc. Rev. 36: 707-718.
    • (2007) Chem. Soc. Rev. , vol.36 , pp. 707-718
    • Quinn, J.F.1    Johnston, A.P.R.2    Such, G.K.3    Zelikin, A.N.4    Caruso, F.5
  • 49
    • 4544382378 scopus 로고    scopus 로고
    • Form and function in multilayer assembly: New applications at the nanoscale
    • Hammond, P. T. (2004) Form and function in multilayer assembly: New applications at the nanoscale. Adv. Mater. 16: 1271-1293.
    • (2004) Adv. Mater. , vol.16 , pp. 1271-1293
    • Hammond, P.T.1
  • 50
    • 0032659433 scopus 로고    scopus 로고
    • Thin polymer layers formed by polyelectrolyte multilayer techniques on biological surfaces
    • Elbert, D. L., C. B. Herbert, and J. A. Hubbell (1999) Thin polymer layers formed by polyelectrolyte multilayer techniques on biological surfaces. Langmuir 15: 5355-5362.
    • (1999) Langmuir , vol.15 , pp. 5355-5362
    • Elbert, D.L.1    Herbert, C.B.2    Hubbell, J.A.3
  • 51
    • 0038208277 scopus 로고    scopus 로고
    • Nanocoatings onto arteries via layer-by-layer deposition: Toward the in vivo repair of damaged blood vessels
    • Thierry, B., F. M. Winnik, Y. Merhi, and M. Tabrizian (2003) Nanocoatings onto arteries via layer-by-layer deposition: toward the in vivo repair of damaged blood vessels. J. Am. Chem. Soc. 125: 7494-7495.
    • (2003) J. Am. Chem. Soc. , vol.125 , pp. 7494-7495
    • Thierry, B.1    Winnik, F.M.2    Merhi, Y.3    Tabrizian, M.4
  • 54
    • 0346634895 scopus 로고    scopus 로고
    • In vitro cytotoxicity testing of polycations: Influence of polymer structure on cell viability and hemolysis
    • Fischer, D., Y. X. Li, B. Ahlemeyer, J. Krieglstein, and T. Kissel (2003) In vitro cytotoxicity testing of polycations: influence of polymer structure on cell viability and hemolysis. Biomaterials 24: 1121-1131.
    • (2003) Biomaterials , vol.24 , pp. 1121-1131
    • Fischer, D.1    Li, Y.X.2    Ahlemeyer, B.3    Krieglstein, J.4    Kissel, T.5
  • 55
    • 53149100989 scopus 로고    scopus 로고
    • Layer-by-layer assembly of a conformal nanothin PEG coating for intraportal islet transplantation
    • Wilson, J. T., W. X. Cui, and E. L. Chaikof (2008) Layer-by-layer assembly of a conformal nanothin PEG coating for intraportal islet transplantation. Nano Lett. 8:1940-1948.
    • (2008) Nano Lett. , vol.8 , pp. 1940-1948
    • Wilson, J.T.1    Cui, W.X.2    Chaikof, E.L.3
  • 56
    • 34548100653 scopus 로고    scopus 로고
    • Highly poly(ethylene) glycolylated islets improve long-term islet allograft survival without immunosuppressive medication
    • Lee, D. Y., S. J. Park, S. Lee, J. H. Nam, and Y. Byun (2007) Highly poly(ethylene) glycolylated islets improve long-term islet allograft survival without immunosuppressive medication. Tissue Eng. 13: 2133-2141.
    • (2007) Tissue Eng. , vol.13 , pp. 2133-2141
    • Lee, D.Y.1    Park, S.J.2    Lee, S.3    Nam, J.H.4    Byun, Y.5
  • 57
    • 33749679216 scopus 로고    scopus 로고
    • Multilayer nanoencapsulation. New approach for immune protection of human pancreatic islets
    • Krol, S., S. del Guerra, M. Grupillo, A. Diaspro, A. Gliozzi, and P. Marchetti (2006) Multilayer nanoencapsulation. New approach for immune protection of human pancreatic islets. Nano Lett. 6: 1933-1939.
    • (2006) Nano Lett. , vol.6 , pp. 1933-1939
    • Krol, S.1    Del Guerra, S.2    Grupillo, M.3    Diaspro, A.4    Gliozzi, A.5    Marchetti, P.6
  • 58
    • 33747846875 scopus 로고    scopus 로고
    • Encapsulation of islets with ultra-thin polyion complex membrane through poly(ethylene glycol)-phospholipids anchored to cell membrane
    • Miura, S., Y. Teramura, and H. Iwata (2006) Encapsulation of islets with ultra-thin polyion complex membrane through poly(ethylene glycol)-phospholipids anchored to cell membrane. Biomaterials 27: 5828-5835.
    • (2006) Biomaterials , vol.27 , pp. 5828-5835
    • Miura, S.1    Teramura, Y.2    Iwata, H.3
  • 59
    • 1542268860 scopus 로고    scopus 로고
    • Immune reactions of lymphocytes and macrophages against PEG-grafted pancreatic islets
    • Jang, J. Y., D. Y. Lee, S. J. Park, and Y. Byun (2004) Immune reactions of lymphocytes and macrophages against PEG-grafted pancreatic islets. Biomaterials 25: 3663-3669.
    • (2004) Biomaterials , vol.25 , pp. 3663-3669
    • Jang, J.Y.1    Lee, D.Y.2    Park, S.J.3    Byun, Y.4
  • 60
    • 0028031970 scopus 로고
    • Indirect recognition by helper cells can induce donor-specific cytotoxic T lymphocytes in vivo
    • Lee, R. S., M. J. Grusby, L. H. Glimcher, H. J. Winn, and H. Auchincloss (1994) Indirect recognition by helper cells can induce donor-specific cytotoxic T lymphocytes in vivo. J. Exp. Med. 179: 865-872.
    • (1994) J. Exp. Med. , vol.179 , pp. 865-872
    • Lee, R.S.1    Grusby, M.J.2    Glimcher, L.H.3    Winn, H.J.4    Auchincloss, H.5
  • 63
    • 0036314243 scopus 로고    scopus 로고
    • Combination therapy with sirolimus and interleukin-2 prevents spontaneous and recurrent autoimmune diabetes in NOD mice
    • Rabinovitch, A., W. L. Suarez-Pinzon, A. M. J. Shapiro, R. V. Rajotte, and R. Power (2002) Combination therapy with sirolimus and interleukin-2 prevents spontaneous and recurrent autoimmune diabetes in NOD mice. Diabetes 51: 638-645.
    • (2002) Diabetes , vol.51 , pp. 638-645
    • Rabinovitch, A.1    Suarez-Pinzon, W.L.2    Shapiro, A.M.J.3    Rajotte, R.V.4    Power, R.5
  • 64
    • 0036186826 scopus 로고    scopus 로고
    • Combination therapy with low dose sirolimus and tacrolimus is synergistic in preventing spontaneous and recurrent autoimmune diabetes in non-obese diabetic mice
    • Shapiro, A. M. J., W. L. Suarez-Pinzon, R. Power, and A. Rabinovitch (2002) Combination therapy with low dose sirolimus and tacrolimus is synergistic in preventing spontaneous and recurrent autoimmune diabetes in non-obese diabetic mice. Diabetologia 45: 224-230.
    • (2002) Diabetologia , vol.45 , pp. 224-230
    • Shapiro, A.M.J.1    Suarez-Pinzon, W.L.2    Power, R.3    Rabinovitch, A.4
  • 65
    • 29244481989 scopus 로고    scopus 로고
    • A combination therapy of PEGylation and immunosuppressive agent for successful islet transplantation
    • Lee, D. Y., S. J. Park, J. H. Nam, and Y. Byun (2006) A combination therapy of PEGylation and immunosuppressive agent for successful islet transplantation. J. Control. Release 110: 290-295.
    • (2006) J. Control. Release , vol.110 , pp. 290-295
    • Lee, D.Y.1    Park, S.J.2    Nam, J.H.3    Byun, Y.4
  • 66
    • 33745768395 scopus 로고    scopus 로고
    • Minimization of immunosuppressive therapy for islet transplantation: Combined action of heme oxygenase-1 and PEGylation to islet
    • Lee, D. Y., J. H. Nam, and Y. Byun (2006) Minimization of immunosuppressive therapy for islet transplantation: combined action of heme oxygenase-1 and PEGylation to islet. Am. J. Transplant. 6: 1820-1828.
    • (2006) Am. J. Transplant. , vol.6 , pp. 1820-1828
    • Lee, D.Y.1    Nam, J.H.2    Byun, Y.3
  • 67
    • 0022637464 scopus 로고
    • Prolonged reversal of diabetes in the rat by transplantation of allogeneic islets from a single donor and cyclosporine treatment
    • Dibelius, A., H. Konigsberger, P. Walter, W. Permanetter, W. Brendel, and B. U. von Specht (1986) Prolonged reversal of diabetes in the rat by transplantation of allogeneic islets from a single donor and cyclosporine treatment. Transplantation 41: 426-431.
    • (1986) Transplantation , vol.41 , pp. 426-431
    • Dibelius, A.1    Konigsberger, H.2    Walter, P.3    Permanetter, W.4    Brendel, W.5    Von Specht, B.U.6
  • 68
    • 0022506020 scopus 로고
    • Immunological characteristics of purified pancreatic islet grafts
    • Gotoh, M., T. Maki, S. Satomi, J. Porter, and A. P. Monaco (1986) Immunological characteristics of purified pancreatic islet grafts. Transplantation 42: 387-390.
    • (1986) Transplantation , vol.42 , pp. 387-390
    • Gotoh, M.1    Maki, T.2    Satomi, S.3    Porter, J.4    Monaco, A.P.5
  • 70
    • 15644379473 scopus 로고    scopus 로고
    • A protective role for heme oxygenase expression in pancreatic islets exposed to interleukin-1beta
    • Ye, J. and S. G. Laychock (1998) A protective role for heme oxygenase expression in pancreatic islets exposed to interleukin-1beta. Endocrinology 139: 4155-4163.
    • (1998) Endocrinology , vol.139 , pp. 4155-4163
    • Ye, J.1    Laychock, S.G.2
  • 71
    • 0035179294 scopus 로고    scopus 로고
    • Heme oxygenase-1 protects pancreatic beta cells from apoptosis caused by various stimuli
    • Tobiasch, E., L. Gunther, and F. H. Bach (2001) Heme oxygenase-1 protects pancreatic beta cells from apoptosis caused by various stimuli. J. Investig. Med. 49: 566-571.
    • (2001) J. Investig. Med. , vol.49 , pp. 566-571
    • Tobiasch, E.1    Gunther, L.2    Bach, F.H.3
  • 72
    • 0014348401 scopus 로고
    • The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase
    • Tenhunen, R., H. S. Marver, and R. Schmid (1968) The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase. Proc. Natl. Acad. Sci. USA 61: 748-755.
    • (1968) Proc. Natl. Acad. Sci. USA , vol.61 , pp. 748-755
    • Tenhunen, R.1    Marver, H.S.2    Schmid, R.3
  • 73
    • 0036127426 scopus 로고    scopus 로고
    • Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice
    • Lee, T. S. and L. Y. Chau (2002) Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice. Nat. Med. 8: 240-246.
    • (2002) Nat. Med. , vol.8 , pp. 240-246
    • Lee, T.S.1    Chau, L.Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.