-
1
-
-
60749137451
-
Beyond chemotherapy: Targeted therapies in ovarian cancer
-
Yap TA, Carden CP, Kaye SB. Beyond chemotherapy: targeted therapies in ovarian cancer. Nat Rev Cancer 2009; 9:167-81.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 167-181
-
-
Yap, T.A.1
Carden, C.P.2
Kaye, S.B.3
-
3
-
-
14644440555
-
Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis
-
Hicklin DJ, Ellis LM. Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis. J Clin Oncol 2005; 23:1011-27.
-
(2005)
J Clin Oncol
, vol.23
, pp. 1011-1027
-
-
Hicklin, D.J.1
Ellis, L.M.2
-
4
-
-
0036174025
-
Vascular endothelial growth factor-165 overexpression stimulates angiogenesis and induces cyst formation and macrophage infiltration in human ovarian cancer xenografts
-
Duyndam MC, Hilhorst MC, Schluper HM, Verheul HM, van Diest PJ, Kraal G, et al. Vascular endothelial growth factor-165 overexpression stimulates angiogenesis and induces cyst formation and macrophage infiltration in human ovarian cancer xenografts. Am J Pathol 2002; 160:537-48. (Pubitemid 34160331)
-
(2002)
American Journal of Pathology
, vol.160
, Issue.2
, pp. 537-548
-
-
Duyndam, M.C.A.1
Hilhorst, M.C.G.W.2
Schluper, H.M.M.3
Verheul, H.M.W.4
Van Diest, P.J.5
Kraal, G.6
Pinedo, H.M.7
Boven, E.8
-
6
-
-
0034648765
-
Angiogenesis in cancer and other diseases
-
Carmeliet P, Jain RK. Angiogenesis in cancer and other diseases. Nature 2000; 407:249-57.
-
(2000)
Nature
, vol.407
, pp. 249-257
-
-
Carmeliet, P.1
Jain, R.K.2
-
7
-
-
16644395747
-
The role of VEGF in the regulation of physiological and pathological angiogenesis
-
Ferrara N. The role of VEGF in the regulation of physiological and pathological angiogenesis. Exs 2005:209-31.
-
(2005)
Exs
, pp. 209-231
-
-
Ferrara, N.1
-
8
-
-
16644381982
-
Role of pericytes in vascular morphogenesis
-
Betsholtz C, Lindblom P, Gerhardt H. Role of pericytes in vascular morphogenesis. Exs 2005; 115-25.
-
(2005)
Exs
, pp. 115-125
-
-
Betsholtz, C.1
Lindblom, P.2
Gerhardt, H.3
-
9
-
-
0242405617
-
Endothelial-pericyte interactions in angiogenesis
-
Gerhardt H, Betsholtz C. Endothelial-pericyte interactions in angiogenesis. Cell Tissue Res 2003; 314:15-23.
-
(2003)
Cell Tissue Res
, vol.314
, pp. 15-23
-
-
Gerhardt, H.1
Betsholtz, C.2
-
10
-
-
12344312042
-
Cellular abnormalities of blood vessels as targets in cancer
-
DOI 10.1016/j.gde.2004.12.005, PII S0959437X04001911, Oncogenes and Cell Proliferation
-
Baluk P, Hashizume H, McDonald DM. Cellular abnormalities of blood vessels as targets in cancer. Curr Opin Genet Dev 2005; 15:102-11. (Pubitemid 40127638)
-
(2005)
Current Opinion in Genetics and Development
, vol.15
, Issue.1
, pp. 102-111
-
-
Baluk, P.1
Hashizume, H.2
McDonald, D.M.3
-
11
-
-
0035972251
-
Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis
-
Hellstrom M, Gerhardt H, Kalen M, Li X, Eriksson U, Wolburg H, et al. Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis. J Cell Biol 2001; 153:543-53. (Pubitemid 34280141)
-
(2001)
Journal of Cell Biology
, vol.152
, Issue.3
, pp. 543-553
-
-
Hellstrom, M.1
Gerhardt, H.2
Kalen, M.3
Li, X.4
Eriksson, U.5
Wolburg, H.6
Betsholtz, C.7
-
12
-
-
0030756325
-
Pericyte loss and microaneurysm formation in PDGF-B-deficient mice
-
DOI 10.1126/science.277.5323.242
-
Lindahl P, Johansson BR, Leveen P, Betsholtz C. Pericyte loss and microaneurysm formation in PDGF-B-deficient mice. Science 1997; 277:242-5. (Pubitemid 27446080)
-
(1997)
Science
, vol.277
, Issue.5323
, pp. 242-245
-
-
Lindahl, P.1
Johansson, B.R.2
Leveen, P.3
Betsholtz, C.4
-
13
-
-
0036124520
-
Abnormalities in pericytes on blood vessels and endothelial sprouts in tumors
-
Morikawa S, Baluk P, Kaidoh T, Haskell A, Jain RK, McDonald DM. Abnormalities in pericytes on blood vessels and endothelial sprouts in tumors. Am J Pathol 2002; 160:985-1000. (Pubitemid 34224587)
-
(2002)
American Journal of Pathology
, vol.160
, Issue.3
, pp. 985-1000
-
-
Morikawa, S.1
Baluk, P.2
Kaidoh, T.3
Haskell, A.4
Jain, R.K.5
McDonald, D.M.6
-
14
-
-
41349089301
-
Impact of vessel maturation on antiangiogenic therapy in ovarian cancer
-
Lu C, Thaker PH, Lin YG, Spannuth W, Landen CN, Merritt WM, et al. Impact of vessel maturation on antiangiogenic therapy in ovarian cancer. Am J Obstet Gynecol 2008; 198:477.
-
(2008)
Am J Obstet Gynecol
, vol.198
, pp. 477
-
-
Lu, C.1
Thaker, P.H.2
Lin, Y.G.3
Spannuth, W.4
Landen, C.N.5
Merritt, W.M.6
-
15
-
-
1042301958
-
Targeting the platelet-derived growth factor receptor in antivascular therapy for human ovarian carcinoma
-
Apte SM, Fan D, Killion JJ, Fidler IJ. Targeting the platelet-derived growth factor receptor in antivascular therapy for human ovarian carcinoma. Clin Cancer Res 2004; 10:897-908.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 897-908
-
-
Apte, S.M.1
Fan, D.2
Killion, J.J.3
Fidler, I.J.4
-
16
-
-
0038476608
-
Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors
-
Bergers G, Song S, Meyer-Morse N, Bergsland E, Hanahan D. Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors. J Clin Invest 2003; 111:1287-95.
-
(2003)
J Clin Invest
, vol.111
, pp. 1287-1295
-
-
Bergers, G.1
Song, S.2
Meyer-Morse, N.3
Bergsland, E.4
Hanahan, D.5
-
17
-
-
34547637867
-
Sequential loss of tumor vessel pericytes and endothelial cells after inhibition of platelet-derived growth factor B by selective aptamer AX102
-
DOI 10.1158/0008-5472.CAN-07-0293
-
Sennino B, Falcon BL, McCauley D, Le T, McCauley T, Kurz JC, et al. Sequential loss of tumor vessel pericytes and endothelial cells after inhibition of platelet-derived growth factor B by selective aptamer AX102. Cancer Res 2007; 67:7358-67. (Pubitemid 47206566)
-
(2007)
Cancer Research
, vol.67
, Issue.15
, pp. 7358-7367
-
-
Sennino, B.1
Falcon, B.L.2
McCauley, D.3
Le, T.4
McCauley, T.5
Kurz, J.C.6
Haskell, A.7
Epstein, D.M.8
McDonald, D.M.9
-
19
-
-
20044396551
-
Blockade of platelet-derived growth factor receptor-beta by CDP860, a humanized, PEGylated di-Fab', leads to fluid accumulation and is associated with increased tumor vascularized volume
-
Jayson GC, Parker GJ, Mullamitha S, Valle JW, Saunders M, Broughton L, et al. Blockade of platelet-derived growth factor receptor-beta by CDP860, a humanized, PEGylated di-Fab', leads to fluid accumulation and is associated with increased tumor vascularized volume. J Clin Oncol 2005; 23:973-81.
-
(2005)
J Clin Oncol
, vol.23
, pp. 973-981
-
-
Jayson, G.C.1
Parker, G.J.2
Mullamitha, S.3
Valle, J.W.4
Saunders, M.5
Broughton, L.6
-
20
-
-
4944266313
-
High interstitial fluid pressure - An obstacle in cancer therapy
-
DOI 10.1038/nrc1456
-
Heldin CH, Rubin K, Pietras K, Ostman A. High interstitial fluid pressure - an obstacle in cancer therapy. Nat Rev Cancer 2004; 4:806-13. (Pubitemid 39331152)
-
(2004)
Nature Reviews Cancer
, vol.4
, Issue.10
, pp. 806-813
-
-
Heldin, C.-H.1
Rubin, K.2
Pietras, K.3
Ostman, A.4
-
21
-
-
11844254414
-
Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy
-
Jain RK. Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science 2005; 307:58-62.
-
(2005)
Science
, vol.307
, pp. 58-62
-
-
Jain, R.K.1
-
22
-
-
0033613119
-
Platelet-derived growth factor β receptor regulates interstitial fluid homeostasis through phosphatidylinositol-3' kinase signaling
-
DOI 10.1073/pnas.96.20.11410
-
Heuchel R, Berg A, Tallquist M, Ahlen K, Reed RK, Rubin K, et al. Platelet-derived growth factor beta receptor regulates interstitial fluid homeostasis through phosphatidylinositol-3′ kinase signaling. Proc Natl Acad Sci USA 1999; 96:11410-5. (Pubitemid 29487394)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.20
, pp. 11410-11415
-
-
Heuchel, R.1
Berg, A.2
Tallquist, M.3
Ahlen, K.4
Reed, R.K.5
Rubin, K.6
Claesson- Welsh, L.7
Heldin, C.-H.8
Soriano, P.9
-
23
-
-
0035297541
-
Ihibition of platelet-derived growth factor receptors reduces interstitial hypertension and increases transcapillary transport in tumors
-
Pietras K, Ostman A, Sjoquist M, Buchdunger E, Reed RK, Heldin CH, et al. Inhibition of platelet-derived growth factor receptors reduces interstitial hypertension and increases transcapillary transport in tumors. Cancer Res 2001; 61:2929-34. (Pubitemid 32691937)
-
(2001)
Cancer Research
, vol.61
, Issue.7
, pp. 2929-2934
-
-
Pietras, K.1
Ostman, A.2
Sjoquist, M.3
Buchdunger, E.4
Reed, R.K.5
Heldin, C.-H.6
Rubin, K.7
-
24
-
-
0141567995
-
STI571 enhances the therapeutic index of epothilone B by a tumor-selective increase of drug uptake
-
Pietras K, Stumm M, Hubert M, Buchdunger E, Rubin K, Heldin CH, et al. STI571 enhances the therapeutic index of epothilone B by a tumor-selective increase of drug uptake. Clin Cancer Res 2003; 9:3779-87. (Pubitemid 37169248)
-
(2003)
Clinical Cancer Research
, vol.9
, Issue.10 I
, pp. 3779-3787
-
-
Pietras, K.1
Stumm, M.2
Hubert, M.3
Buchdunger, E.4
Rubin, K.5
Heldin, C.-H.6
McSheehy, P.7
Wartmann, M.8
Ostman, A.9
-
25
-
-
36849019301
-
Phase II trial of bevacizumab in persistent or recurrent epithelial ovarian cancer or primary peritoneal cancer: A Gynecologic Oncology Group Study
-
Burger RA, Sill MW, Monk BJ, Greer BE, Sorosky JI. Phase II trial of bevacizumab in persistent or recurrent epithelial ovarian cancer or primary peritoneal cancer: a Gynecologic Oncology Group Study. J Clin Oncol 2007; 25:5165-71.
-
(2007)
J Clin Oncol
, vol.25
, pp. 5165-5171
-
-
Burger, R.A.1
Sill, M.W.2
Monk, B.J.3
Greer, B.E.4
Sorosky, J.I.5
-
26
-
-
37849035249
-
Phase II clinical trial of bevacizumab and low-dose metronomic oral cyclophosphamide in recurrent ovarian cancer: A trial of the California, Chicago and Princess Margaret Hospital phase II consortia
-
Garcia AA, Hirte H, Fleming G, Yang D, Tsao-Wei DD, Roman L, et al. Phase II clinical trial of bevacizumab and low-dose metronomic oral cyclophosphamide in recurrent ovarian cancer: a trial of the California, Chicago and Princess Margaret Hospital phase II consortia. J Clin Oncol 2008; 26:76-82.
-
(2008)
J Clin Oncol
, vol.26
, pp. 76-82
-
-
Garcia, A.A.1
Hirte, H.2
Fleming, G.3
Yang, D.4
Tsao-Wei, D.D.5
Roman, L.6
|