Structural optimization of photoswitch ligands for surface attachment of α-chymotrypsin and regulation of its surface binding

Chemistry - A European Journal

Volumn 16, Issue 23, 2010, Pages 6983-6992

  Pearson, David ^a   Abell, Andrew D ^b  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b UNIVERSITY OF MUNICH   (Germany)

Author keywords

Azo compounds; Enzyme inhibitors; Photoswitching surface chemistry; Surface plasmon resonance

Indexed keywords

AZIDE-ALKYNE CYCLOADDITION; AZO COMPOUND; AZOBENZENE GROUP; ENZYME BINDING; ENZYME INHIBITORS; GOLD SURFACES; INHIBITION CONSTANTS; KETO ESTER; MODIFIED SURFACES; PHOTOREGULATED BINDING; PHOTOSWITCHING; PHOTOSWITCHING SURFACE CHEMISTRY; REVERSIBLE CHANGE; SURFACE ATTACHMENT; SURFACE BINDING; TRIFLUOROMETHYLKETONE; TWO-STEP PROCEDURE;

ACETYLENE; CAPILLARITY; ENZYMES; ESTERS; GOLD METALLURGY; ISOMERIZATION; KETONES; PLASMONS; STRUCTURAL DESIGN; STRUCTURAL OPTIMIZATION; SURFACE CHEMISTRY; SURFACE PLASMON RESONANCE;

ENZYME ACTIVITY;

ALPHA-CHYMOTRYPSIN; AZO COMPOUND; CHYMOTRYPSIN; CHYMOTRYPSIN A; ENZYME INHIBITOR; GOLD; LIGAND; PROTEINASE INHIBITOR;

ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; PHOTOCHEMISTRY; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION; SURFACE PROPERTY;

AZO COMPOUNDS; BINDING SITES; CHYMOTRYPSIN; ENZYME INHIBITORS; GOLD; LIGANDS; MODELS, MOLECULAR; PHOTOCHEMISTRY; PROTEASE INHIBITORS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; SURFACE PROPERTIES;

EID: 77953560752     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.200903369     Document Type: Article

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