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Volumn 4, Issue 2, 2010, Pages 176-179

Numb: A new player in EMT

Author keywords

Adhesion; Cell polarity; E cadherin; EMT; Numb; Tyrosine kinase

Indexed keywords

ATYPICAL PROTEIN KINASE C; BETA CATENIN; F ACTIN; PHOSPHOTYROSINE; PROTEIN KINASE; PROTEIN KINASE C; PROTEIN NUMB; PROTEIN PAR 3; PROTEIN TYROSINE KINASE; SCATTER FACTOR; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; UVOMORULIN; CADHERIN; MEMBRANE PROTEIN;

EID: 77953559086     PISSN: 19336918     EISSN: 19336926     Source Type: Journal    
DOI: 10.4161/cam.4.2.10690     Document Type: Note
Times cited : (28)

References (30)
  • 1
    • 33244463813 scopus 로고    scopus 로고
    • Complex networks orchestrate epithelial-mesenchymal transitions
    • Thiery JP, Sleeman JP. Complex networks orchestrate epithelial- mesenchymal transitions. Nat Rev Mol Cell Biol 2006; 7:131-42.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 131-142
    • Thiery, J.P.1    Sleeman, J.P.2
  • 2
    • 34250820373 scopus 로고    scopus 로고
    • Numb controls integrin endocytosis for directional cell migration with aPKC and PAR-3
    • Nishimura T, Kaibuchi K. Numb controls integrin endocytosis for directional cell migration with aPKC and PAR-3. Dev Cell 2007; 13:15-28.
    • (2007) Dev Cell , vol.13 , pp. 15-28
    • Nishimura, T.1    Kaibuchi, K.2
  • 3
    • 34347359603 scopus 로고    scopus 로고
    • Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors
    • Rasin MR, Gazula VR, Breunig JJ, Kwan KY, Johnson MB, Liu-Chen S, et al. Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors. Nat Neurosci 2007; 10:819-27.
    • (2007) Nat Neurosci , vol.10 , pp. 819-827
    • Rasin, M.R.1    Gazula, V.R.2    Breunig, J.J.3    Kwan, K.Y.4    Johnson, M.B.5    Liu-Chen, S.6
  • 4
    • 16244422687 scopus 로고    scopus 로고
    • Linking epithelial-mesenchymal transition to the well-known polarity protein Par6
    • Thiery JP, Huang R. Linking epithelial-mesenchymal transition to the well-known polarity protein Par6. Dev Cell 2005; 8:456-8.
    • (2005) Dev Cell , vol.8 , pp. 456-458
    • Thiery, J.P.1    Huang, R.2
  • 5
    • 45849146998 scopus 로고    scopus 로고
    • Basolateral junctions utilize warts signaling to control epithelial-mesenchymal transition and proliferation crucial for migration and invasion of Drosophila ovarian epithelial cells
    • Zhao M, Szafranski P, Hall CA, Goode S. Basolateral junctions utilize warts signaling to control epithelial-mesenchymal transition and proliferation crucial for migration and invasion of Drosophila ovarian epithelial cells. Genetics 2008; 178:1947-71.
    • (2008) Genetics , vol.178 , pp. 1947-1971
    • Zhao, M.1    Szafranski, P.2    Hall, C.A.3    Goode, S.4
  • 6
    • 69249209681 scopus 로고    scopus 로고
    • Numb regulates cell-cell adhesion and polarity in response to tyrosine kinase signalling
    • Wang Z, Sandiford S, Wu C, Li SS. Numb regulates cell-cell adhesion and polarity in response to tyrosine kinase signalling. EMBO J 2009; 28:2360-73.
    • (2009) EMBO J , vol.28 , pp. 2360-2373
    • Wang, Z.1    Sandiford, S.2    Wu, C.3    Li, S.S.4
  • 7
    • 0024980213 scopus 로고
    • Numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos
    • Uemura T, Shepherd S, Ackerman L, Jan LY, Jan YN. numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos. Cell 1989; 58:349-60.
    • (1989) Cell , vol.58 , pp. 349-360
    • Uemura, T.1    Shepherd, S.2    Ackerman, L.3    Jan, L.Y.4    Jan, Y.N.5
  • 8
    • 33847400147 scopus 로고    scopus 로고
    • PARtitioning numb
    • Casanova JE. PARtitioning numb. EMBO Rep 2007; 8:233-5.
    • (2007) EMBO Rep , vol.8 , pp. 233-235
    • Casanova, J.E.1
  • 10
    • 33845615901 scopus 로고    scopus 로고
    • Notch and Numb are required for normal migration of peripheral glia in Drosophila
    • Edenfeld G, Altenhein B, Zierau A, Cleppien D, Krukkert K, Technau G, et al. Notch and Numb are required for normal migration of peripheral glia in Drosophila. Dev Biol 2007; 301:27-37.
    • (2007) Dev Biol , vol.301 , pp. 27-37
    • Edenfeld, G.1    Altenhein, B.2    Zierau, A.3    Cleppien, D.4    Krukkert, K.5    Technau, G.6
  • 11
    • 0036121308 scopus 로고    scopus 로고
    • Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex
    • Fujita Y, Krause G, Scheffner M, Zechner D, Leddy HE, Behrens J, et al. Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex. Nat Cell Biol 2002; 4:222-31.
    • (2002) Nat Cell Biol , vol.4 , pp. 222-231
    • Fujita, Y.1    Krause, G.2    Scheffner, M.3    Zechner, D.4    Leddy, H.E.5    Behrens, J.6
  • 12
    • 33750489040 scopus 로고    scopus 로고
    • Tyrosine phosphorylated Par3 regulates epithelial tight junction assembly promoted by EGFR signaling
    • Wang Y, Du D, Fang L, Yang G, Zhang C, Zeng R, et al. Tyrosine phosphorylated Par3 regulates epithelial tight junction assembly promoted by EGFR signaling. EMBO J 2006; 25:5058-70.
    • (2006) EMBO J , vol.25 , pp. 5058-5070
    • Wang, Y.1    Du, D.2    Fang, L.3    Yang, G.4    Zhang, C.5    Zeng, R.6
  • 13
    • 70350458156 scopus 로고    scopus 로고
    • Proteomic, Functional and Motif-Based Analysis of C-terminal Src Kinase (Csk)-interacting Proteins
    • Yang G, Li Q, Ren S, Lu X, Fang L, Zhou W, et al. Proteomic, Functional and Motif-Based Analysis of C-terminal Src Kinase (Csk)-interacting Proteins. Proteomics 2009.
    • (2009) Proteomics
    • Yang, G.1    Li, Q.2    Ren, S.3    Lu, X.4    Fang, L.5    Zhou, W.6
  • 15
    • 47749130863 scopus 로고    scopus 로고
    • Par3/Par6 polarity complex coordinates apical ectoplasmic specialization and blood-testis barrier restructuring during spermatogenesis
    • Wong EW, Mruk DD, Lee WM, Cheng CY. Par3/Par6 polarity complex coordinates apical ectoplasmic specialization and blood-testis barrier restructuring during spermatogenesis. Proc Natl Acad Sci USA 2008; 105:9657-62.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 9657-9662
    • Wong, E.W.1    Mruk, D.D.2    Lee, W.M.3    Cheng, C.Y.4
  • 17
    • 54549108389 scopus 로고    scopus 로고
    • Active Rab11 and functional recycling endosome are required for E-cadherin trafficking and lumen formation during epithelial morphogenesis
    • Desclozeaux M, Venturato J, Wylie FG, Kay JG, Joseph SR, Le HT, et al. Active Rab11 and functional recycling endosome are required for E-cadherin trafficking and lumen formation during epithelial morphogenesis. Am J Physiol Cell Physiol 2008; 295:545-56.
    • (2008) Am J Physiol Cell Physiol , vol.295 , pp. 545-556
    • Desclozeaux, M.1    Venturato, J.2    Wylie, F.G.3    Kay, J.G.4    Joseph, S.R.5    Le, H.T.6
  • 18
    • 24144503375 scopus 로고    scopus 로고
    • Asymmetric Rab 11 endosomes regulate delta recycling and specify cell fate in the Drosophila nervous system
    • Emery G, Hutterer A, Berdnik D, Mayer B, Wirtz-Peitz F, Gaitan MG, et al. Asymmetric Rab 11 endosomes regulate delta recycling and specify cell fate in the Drosophila nervous system. Cell 2005; 122:763-73.
    • (2005) Cell , vol.122 , pp. 763-773
    • Emery, G.1    Hutterer, A.2    Berdnik, D.3    Mayer, B.4    Wirtz-Peitz, F.5    Gaitan, M.G.6
  • 19
    • 35549001736 scopus 로고    scopus 로고
    • The PAR proteins: Fundamental players in animal cell polarization
    • Goldstein B, Macara IG. The PAR proteins: fundamental players in animal cell polarization. Dev Cell 2007; 13:609-22.
    • (2007) Dev Cell , vol.13 , pp. 609-622
    • Goldstein, B.1    Macara, I.G.2
  • 20
    • 0042346345 scopus 로고    scopus 로고
    • Cell polarity: The ups and downs of the Par6/aPKC complex
    • Henrique D, Schweisguth F. Cell polarity: the ups and downs of the Par6/aPKC complex. Curr Opin Genet Dev 2003; 13:341-50.
    • (2003) Curr Opin Genet Dev , vol.13 , pp. 341-350
    • Henrique, D.1    Schweisguth, F.2
  • 21
    • 0036828968 scopus 로고    scopus 로고
    • Regulated protein-protein interaction between aPKC and PAR-3 plays an essential role in the polarization of epithelial cells
    • Nagai-Tamai Y, Mizuno K, Hirose T, Suzuki A, Ohno S. Regulated protein-protein interaction between aPKC and PAR-3 plays an essential role in the polarization of epithelial cells. Genes Cells 2002; 7:1161-71.
    • (2002) Genes Cells , vol.7 , pp. 1161-1171
    • Nagai-Tamai, Y.1    Mizuno, K.2    Hirose, T.3    Suzuki, A.4    Ohno, S.5
  • 22
    • 34247593781 scopus 로고    scopus 로고
    • APKC controls microtubule organization to balance adherens junction symmetry and planar polarity during development
    • Harris TJ, Peifer M. aPKC controls microtubule organization to balance adherens junction symmetry and planar polarity during development. Dev Cell 2007; 12:727-38.
    • (2007) Dev Cell , vol.12 , pp. 727-738
    • Harris, T.J.1    Peifer, M.2
  • 23
    • 0034253536 scopus 로고    scopus 로고
    • The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42
    • Joberty G, Petersen C, Gao L, Macara IG. The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42. Nat Cell Biol 2000; 2:531-9.
    • (2000) Nat Cell Biol , vol.2 , pp. 531-539
    • Joberty, G.1    Petersen, C.2    Gao, L.3    Macara, I.G.4
  • 24
    • 33750505436 scopus 로고    scopus 로고
    • Par6-aPKC uncouples ErbB2 induced disruption of polarized epithelial organization from proliferation control
    • Aranda V, Haire T, Nolan ME, Calarco JP, Rosenberg AZ, Fawcett JP, et al. Par6-aPKC uncouples ErbB2 induced disruption of polarized epithelial organization from proliferation control. Nat Cell Biol 2006; 8:1235-45.
    • (2006) Nat Cell Biol , vol.8 , pp. 1235-1245
    • Aranda, V.1    Haire, T.2    Nolan, M.E.3    Calarco, J.P.4    Rosenberg, A.Z.5    Fawcett, J.P.6
  • 25
    • 27944479854 scopus 로고    scopus 로고
    • Rho GTPases: Biochemistry and biology
    • Jaffe AB, Hall A. Rho GTPases: biochemistry and biology. Annu Rev Cell Dev Biol 2005; 21:247-69.
    • (2005) Annu Rev Cell Dev Biol , vol.21 , pp. 247-269
    • Jaffe, A.B.1    Hall, A.2
  • 27
    • 0000202186 scopus 로고    scopus 로고
    • A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity
    • Lin D, Edwards AS, Fawcett JP, Mbamalu G, Scott JD, Pawson T. A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity. Nat Cell Biol 2000; 2:540-7.
    • (2000) Nat Cell Biol , vol.2 , pp. 540-547
    • Lin, D.1    Edwards, A.S.2    Fawcett, J.P.3    Mbamalu, G.4    Scott, J.D.5    Pawson, T.6
  • 28
    • 33644858848 scopus 로고    scopus 로고
    • Role of numb in dendritic spine development with a Cdc42 GEF intersectin and EphB2
    • Nishimura T, Yamaguchi T, Tokunaga A, Hara A, Hamaguchi T, Kato K, et al. Role of numb in dendritic spine development with a Cdc42 GEF intersectin and EphB2. Mol Biol Cell 2006; 17:1273-85.
    • (2006) Mol Biol Cell , vol.17 , pp. 1273-1285
    • Nishimura, T.1    Yamaguchi, T.2    Tokunaga, A.3    Hara, A.4    Hamaguchi, T.5    Kato, K.6
  • 29
    • 14744289370 scopus 로고    scopus 로고
    • Par-3 controls tight junction assembly through the Rac exchange factor Tiam1
    • DOI 10.1038/ncb1226
    • Chen X, Macara IG. Par-3 controls tight junction assembly through the Rac exchange factor Tiam1. Nat Cell Biol 2005; 7:262-9. (Pubitemid 40331127)
    • (2005) Nature Cell Biology , vol.7 , Issue.3 , pp. 262-269
    • Chen, X.1    Macara, I.G.2
  • 30


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