Development and validation of a pressurised liquid extraction liquid chromatography-electrospray-tandem mass spectrometry method for β-lactams and sulfonamides in animal feed

Journal of Chromatography A

Volumn 1217, Issue 26, 2010, Pages 4247-4254

  Kantiani, Lina ^a   Farré, Marinella ^a   Freixiedas, Josep Manuel Grases i ^b   Barceló, Damiá ^a,c  

^a INSTITUTE OF ENVIRONMENTAL ASSESSMENT AND WATER RESEARCH   (Spain)

^b Alimentary Section   (Spain)

^c KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

Animal feed; Cephalosporins; LC ESI MS MS; Penicillins; SPE; Sulfonamides

Indexed keywords

AMOXICILLIN; ANALYTES; ANIMAL FEED; ANTIBACTERIALS; AS EXTRACTION; CEFOPERAZONE; ELECTROSPRAY TANDEM MASS SPECTROMETRY; EXTRACTION TIME; FEED SAMPLES; GROWTH PROMOTERS; ION-TRAP MASS SPECTROMETRY; LC/ESI-MS; LIMITS OF DETECTION; LINEARITY COEFFICIENT; LOW CONCENTRATIONS; MATRIX; PENICILLIN V; PRE-CONCENTRATION PROCEDURES; PRESSURISED LIQUID EXTRACTION; QUADRUPOLES; REPRODUCIBILITIES; SOLID-PHASE EXTRACTION; SULFAPYRIDINE; VALIDATED METHODS;

AMIDES; ANIMALS; DRUG PRODUCTS; LAWS AND LEGISLATION; LIQUID CHROMATOGRAPHY; LIQUIDS; MASS SPECTROMETRY; SEWAGE TREATMENT PLANTS; SULFUR COMPOUNDS;

SOLVENT EXTRACTION;

AMOXICILLIN; AMPICILLIN; BETA LACTAM; CEFALEXIN; CEFAZOLIN; CEFOPERAZONE; CEFTIOFUR; CEPHALOSPORIN DERIVATIVE; CLOXACILLIN; DICLOXACILLIN; OXACILLIN; PENICILLIN DERIVATIVE; PENICILLIN G; PENICILLIN V; SULFADIAZINE; SULFADIMETHOXINE; SULFAMETHOXYPYRIDAZINE; SULFAPYRIDINE; SULFAQUINOXALINE; SULFONAMIDE;

ANIMAL FOOD; ARTICLE; CONTROLLED STUDY; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; ION TRAP MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; PROCESS DEVELOPMENT; REPRODUCIBILITY; VALIDATION PROCESS;

ANIMAL FEED; BETA-LACTAMS; CHROMATOGRAPHY, LIQUID; SOLID PHASE EXTRACTION; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SULFONAMIDES; TANDEM MASS SPECTROMETRY;

ANIMALIA;

EID: 77953541148     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2010.04.029     Document Type: Article

References (25)

1. Tollefson L., Miller M.A. J. AOAC Int. 2000, 83:245.
2. De Baere S., De Backer P. Anal. Chim. Acta 2007, 586:319.
3. Kantiani L., Farré M., Barceló D. Trends Anal. Chem. 2009, 28:729.
4. Kan C.A., Meijer G.A.L. Anim. Feed Sci. Technol. 2007, 133:84.
5. McEvoy J.D.G., Higgins H.C., Mayne C.S., Kennedy D.G. In: Proceedings of the Euroresidue IV 2000, 753.
6. McEvoy J.D.G., Mayne C.S., Higgins H.C., Kennedy D.G. Vet. Rec. 1999, 144:470.
7. Blüthgen A.H. Bull. Int. Dairy Feder. 2000, 356:43.
8. Bogialli S., Capitolino V., Curini R., Di Corcia A., Nazzari M., Sergi M. J. Agric. Food Chem. 2004, 52:3286.
9. Wang S., Zhang H.Y., Wang L., Duan Z.J., Kennedy I. Food Addit. Contam. 2006, 23:362.
10. Commission Decision (EC) No. 2002/657/EC of 12 August 2002 implementing Council Directive 96/23/EC concerning the performance of analytical methods and the interpretation of results, Official Journal L221, 17/08/2002, pp. 8-36.
11. Commission Regulation (EC) 2377/90, Official Journal of the European Communities L 224 (26 June 1990), p. 1.
12. Council Regulation No. 2821/98 of 17 December 1998 amending, as regards withdrawal of the authorisation of certain antibiotics, Directive 70/524/EEC concerning additives in feeding stuffs, Official Journal L351, 29/12/1998, pp. 4-8.
13. Commission Regulation (EC) No. 2788/98 of 22 December 1998 amending Council Directive 70/524/EEC concerning additives in feeding stuffs as regards the withdrawal of authorisation for certain growth promoters. Official Journal L 347, 23/12/1998, pp. 31-32.
14. Commission Regulation (EC) No. 1831/2003 of 22 September 2003 on additives for use in animal nutrition, replacing Directive 70/524/EEC on additives in feeding-stuffs. Official Journal L 268, 22/09/2003, pp. 29-43.
15. Codex committee on residues of veterinary drugs in food, Comments from the European community on veterinary drugs without ADI/MRL,Available from: of 22/04/2005, accessed 10.03.10). http://ec.europa.eu/food/fs/ifsi/eupositions/ccrdvf/archives/ccrvdf_comments_2004_50_en.pdf.
16. Benito-Peña E., Urraca J.L., Moreno-Bondi M.C. J. Pharm. Biomed. Anal. 2009, 49:289.
17. Gamba V., Dusi G. Anal. Chim. Acta 2003, 483:69.
18. Pérez-Lozano P., García-Montoya E., Orriols A., Miñarro M., Ticó J.R., Suñé-Negre J.M. J. Pharm. Biomed. Anal. 2006, 42:192.
19. Vincent U., Chedin M., Yasar S., von Holst C. J. Pharm. Biomed. Anal. 2008, 47:750.
20. Kantiani L., Farré M., Sibum M., Postigo C., De Alda M.L., Barceló D. Anal. Chem. 2009, 81:4285.
21. Mastovska K., Lightfield A.R. J. Chromatogr. A 2008, 1202:118.
22. Pozo O.J., Guerrero C., Sancho J.V., Ibáñez M., Pitarch E., Hogendoorn E., Hernández F. J. Chromatogr. A 2006, 1103:83.
23. Tyczkowska K.L., Voyksner R.D., Aronson A.L. J. Chromatogr. 1992, 594:195.
24. Grunwald L., Petz M. Anal. Chim. Acta 2003, 483:73.
25. Canadian food inspection agency, Available from: (accessed 10.03.10). http://www.inspection.gc.ca/.