Simple and rapid liquid chromatography-tandem mass spectrometry confirmatory assay for determining amoxicillin and ampicillin in bovine tissues and milk

Journal of Agricultural and Food Chemistry

Volumn 52, Issue 11, 2004, Pages 3286-3291

  Bogialli, Sara ^a   Capitolino, Vittorio ^a   Curini, Roberta ^a   Di Corcia, Antonio ^a   Nazzari, Manuela ^a   Sergi, Manuel ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Amoxicillin; Ampicillin; Bovine; LC MS MS; Milk; Tissues

Indexed keywords

AMOXICILLIN; AMPICILLIN; PENICILLIN DERIVATIVE; PENICILLIN V;

ACIDIFICATION; ANIMAL TISSUE; ARTICLE; CATTLE; CHROMATOGRAPHY; CONTROLLED STUDY; DISPERSION; DRUG DETERMINATION; DRUG MILK LEVEL; DRUG TISSUE LEVEL; EXTRACTION; FILTRATION; KIDNEY; LIQUID CHROMATOGRAPHY; LIVER; MILK; MUSCLE; NONHUMAN; PRODUCT RECOVERY; SOLID; STANDARD; TANDEM MASS SPECTROMETRY;

AMOXICILLIN; AMPICILLIN; ANIMALS; ANTI-BACTERIAL AGENTS; CATTLE; CHROMATOGRAPHY, LIQUID; KIDNEY; LIVER; MEAT; MILK; MUSCLES; QUALITY CONTROL; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

ANIMALIA; BOS TAURUS; BOVINAE;

EID: 2542439133     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf0499572     Document Type: Article

References (20)

1. Commision Regulation (EC) 508/1999 of 4/3/1999 amending Annexes I-IV to Council Regulation (EEC) 2377/90 laying down a Community procedure for the establishment of maximum residue limits of veterinary medicinal products in foodstuffs of animal origin. Off. J. Eur. Communities 1999, No. L60, 16.
2. U.S. Food and Drug Administration. National Milk Drug Residue Base; Fiscal Year 1996 Annual Report, Oct 1, 1995-Sept 30, 1996; GLH, Inc.: Lighthouse Point, FL, Feb 10, 1997.
3. McGrane, M.; O'Keeffe M.; Smyth, M. R. Multi-residue analysis of penicillin residues in porcine tissue using solid matrix phase dispersion. Analyst 1998, 123, 2779-2783.
4. Moats, W. A.; Romanowski, R. D. Multiresidue determination of β-lactam antibiotics in milk and tissues with the aid of high-performance liquid chromatographic fractionation for clean up. J. Chromatogr. A 1998, 812, 237-247.
5. Verdon, E.; Couërdor, P. Multiresidue analytical method for the determination of eight penicillin antibiotics in muscle tissue by ion-pair reversed-phase HPLC after precolumn derivatization. J. AOAC Int. 1999, 82, 1083-1095.
6. Søorensen, L. K.; Snor, L. K.; Elkær, T.; Hansen, H. Simultaneous determination of seven penicillins in muscle, liver and kidney tissue from cattle and pigs by multiresidue high-performance liquid chromatographic method. J. Chromatogr. B 1999, 734, 307-318.
7. Gamba, V.; Dusi, G. Liquid chromatography with fluorescence detection of amoxicillin and ampicillin in feeds using pre-column derivatization, Anal. Chim. Acta 2003, 483, 69-72.
8. Ang, C. Y. W.; Liu, F. F.; Lay, J. O.; Wenong, L.; McKim, K.; Gehring, T.; Lochmann, R. Liquid chromatographic analysis of incurred amoxicillin residues in catfish muscle following oral administration of the drug. J. Agric. Food Chem. 2000, 48, 1673-1677.
9. Riediker, S.; Diserens, J.; Stadler, R. H. Analysis of β-lactam antibiotics in incurred raw milk by rapid test methods and liquid chromatography coupled with electrospray ionization tandem mass spectrometry. J. Agric. Food Chem. 2001, 49, 4171-4176.
10. De Baere, S.; Cherlet, M.; Baert, K.; De Backer, P. Quantitative analysis of amoxicillin and its major metabolites in animal tissues by liquid chromatography combined with electrospray ionization tandem mass spectrometry. Anal. Chem. 2002, 74, 1393-1401.
11. Holstege, D. M.; Puschner, B.; Whitehead, G.; Galey, F. D. Screening and mass spectral confirmation of β-lactam antibiotic residues in milk using LC-MS/MS. J. Agric. Food Chem 2002, 50, 406-411.
12. Commission Decision 2002/657/EC of 12 August 2002 Implementing Council Directive (EC) 96/23 concerning the performance of analytical methods and the interpretation of the results (text with EEA relevance). Off. J. Eur. Communities 2002, No. L221, 8-36.
13. Barker, S. A.; Long, A. R.; Short, C. R. Isolation of drug residues from tissues by solid-phase dispersion. J. Chromatogr. A 1989, 475, 353-361.
14. Barker, S. A. Matrix solid-phase dispersion. J. Chromatogr. A 2000, 885, 115-127.
15. McLaughlin, L. G.; Henion, J. D.; Kijak, P. J. Multiresidue confirmation of aminoglycoside antibiotics in bovine kidney by ion spray high-performance liquid chromatography/tandem mass spectrometry. Biol. Mass Spectrom. 1994, 23, 417-429.
16. Bogialli, S.; Curini, R.; Di Corcia, A.; Nazzari, M.; Samperi, R.A. LC-MS assay for analyzing sulfonamide antibacterials in cattle and fish muscle tissues. Anal. Chem. 2003, 75, 1798-1804.
17. Bogialli, S.; Curini, R.; Di Corcia, A.; Nazzari, M.; Sergi, M. Confirmatory analysis of sulfonamide antibacterials in bovine liver and kidney: extraction with hot water and liquid chromatography coupled to a single- or triple-quadrupole mass spectrometer. Rapid Commun. Mass Spectrom. 2003, 17, 1146-1156.
18. Bogialli, S.; Curini, R.; Di Corcia, A.; Nazzari, M.; Polci, M. L. Rapid confirmatory assay for determining 12 sulfonamide antimicrobials in milk and eggs by matrix solid-phase dispersion and liquid chromatography-mass spectrometry. J. Agric. Food Chem. 2003, 51, 4225-4232.
19. Crescenzi, C.; D'Ascenzo, G.; Di Corcia, A.; Nazzari, M.; Marchese, S.; Samperi, R. Multiresidue herbicide analysis in soil: subcritical water extraction with an on-line sorbent trap. Anal. Chem. 1999, 71, 2157-2163.
20. Matuszewski, B. K.; Constanzer, M. L.; Chavez-Eng, C. M. Matrix effect in quantitative Ic/ms/ms analyses of biological fluids: a method for determination of finasteride in human plasma at picogram per milliliter concentrations, Anal. Chem. 1998, 70, 882-889.