Protein adducts of 1,4-benzoquinone and benzene oxide among smokers and nonsmokers exposed to benzene in China

Cancer Epidemiology Biomarkers and Prevention

Volumn 10, Issue 8, 2001, Pages 831-838

  Yeowell O'Connell, Karen ^a   Rothman, Nathaniel ^b   Waidyanatha, Suramya ^a   Smith, Martyn T ^c   Hayes, Richard B ^b   Li, Guilan ^d   Bechtold, William E ^e   Dosemeci, Mustafa ^b   Zhang, Luopin ^c   Yin, Songnian ^d   Rappaport, Stephen M ^a  

^a University of North Carolina at Chapel Hill   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^e LOVELACE RESPIRATORY RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 BENZOQUINONE; ALBUMIN; BENZENE; BENZENE DERIVATIVE; BENZENE EPOXIDE; BIOLOGICAL MARKER; HEMOGLOBIN; HYDROQUINONE; PHENOL; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL ANALYSIS; CHINA; CIGARETTE SMOKING; CLINICAL ARTICLE; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; GAS CHROMATOGRAPHY; HUMAN; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN ANALYSIS;

BENZENE; BENZOQUINONES; CROSS-SECTIONAL STUDIES; CYCLOHEXANES; ENVIRONMENTAL EXPOSURE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HEMOGLOBINS; HUMANS; SMOKING;

EID: 0034896132     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Benzene
2. The toxicology of benzene
3. Measurement of benzene oxide in the blood of rats following administration of benzene
4. An overview of benzene metabolism
5. Reduction of benzene metabolism and toxicity in mice that lack CYP2E1 expression
6. Chemistry of muconaldehydes of possible relevance to the toxicology of benzene
7. Metabolic basis of benzene toxicity
8. The use of protein adducts to investigate the disposition of reactive metabolites of benzene
9. Synthesis and characterization of deoxyguanosine-benzoquinone adducts
10. 14C-deoxyguanosine 5′-phosphate
11. Peroxidase-dependent metabolism of benzene's phenolic metabolites and its potential role in benzene toxicity and carcinogenicity
12. Interaction of p-benzoquinone and p-biphenoquinone with microtubule proteins in vitro
13. Differential inhibition of DNA synthesis in human T cells by the cigarette tar components hydroquinone and catechol
14. Formation of hemoglobin and albumin adducts of benzene oxide in mouse, rat, and human blood
15. Determination of catechol and quinol in the urine of workers exposed to benzene
16. Human exposure to naturally occurring hydroquinone
17. Validation of biomarkers in humans exposed to benzene: Urine metabolites
18. Hemoglobin and albumin adducts of benzene oxide among workers exposed to high levels of benzene
19. S-phenylcysteine in albumin as a benzene biomarker
20. A new assay for albumin and hemoglobin adducts of 1,2- and 1,4-benzoquinones
21. Measurement of adducts of benzoquinone with hemoglobin and albumin
22. 6]benzene
23. Analysis of hemoglobin adducts of benzene oxide by gas chromatography-mass spectrometry
24. Urinary excretion of phenol, catechol, hydroquinone, and muconic acid by workers occupationally exposed to benzene
25. Urinary benzene as a biomarker of exposure among occupationally-exposed and unexposed subjects
26. Hematotoxicity among Chinese workers heavily exposed to benzene
27. Identification of multi-S-substituted conjugates of hydroquinone by HPLC-coulometric electrode array analysis and mass spectrometry
28. Assessment of long-term exposures to toxic substances in air
29. Unequal variances
30. Environmental exposure to benzene: An update
31. Analysis of S-phenyl-L-cysteine in globin as a marker of benzene exposure
32. Shifting from a conventional diet to an uncooked vegan diet reversibly alters fecal hydrolytic activities in humans
33. A high performance liquid chromatographic determination of major phenolic compounds in tobacco smoke
34. Relationships between smoking habits, smoking-associated hematological changes, and urinary benzene metabolites
35. Elevated levels of benzene-related compounds in the urine of cigarette smokers
36. 6] benzene to rats