-
1
-
-
33645524176
-
Effect of very highintensity statin therapy on regression of coronary atherosclerosis: The ASTEROID trial
-
Nissen SE, Nicholls SJ, Sipahi I, et al.: Effect of very highintensity statin therapy on regression of coronary atherosclerosis: the ASTEROID trial. JAMA 2006, 295:1556-1565.
-
(2006)
JAMA
, vol.295
, pp. 1556-1565
-
-
Nissen, S.E.1
Nicholls, S.J.2
Sipahi, I.3
-
2
-
-
42149154618
-
Microsomal prostaglandin E synthase-1 inhibition in cardiovascular inflammatory disease
-
Wang M, Song WL, Cheng Y, Fitzgerald GA: Microsomal prostaglandin E synthase-1 inhibition in cardiovascular inflammatory disease. J Intern Med 2008, 263:500-505.
-
(2008)
J Intern Med
, vol.263
, pp. 500-505
-
-
Wang, M.1
Song, W.L.2
Cheng, Y.3
Fitzgerald, G.A.4
-
3
-
-
69849107198
-
Inhibition of soluble epoxide hydrolase attenuated atherosclerosis, abdominal aortic aneurysm formation, and dyslipidemia
-
This article investigated the antiinflammatory mechanisms involved in the anti-atherosclerotic effects of sEH inhibitors
-
Zhang LN, Vincelette J, Cheng Y, et al.: Inhibition of soluble epoxide hydrolase attenuated atherosclerosis, abdominal aortic aneurysm formation, and dyslipidemia. Arterioscler Thromb Vasc Biol 2009, 29:1265-1270. This article investigated the antiinflammatory mechanisms involved in the anti-atherosclerotic effects of sEH inhibitors.
-
(2009)
Arterioscler Thromb Vasc Biol
, vol.29
, pp. 1265-1270
-
-
Zhang, L.N.1
Vincelette, J.2
Cheng, Y.3
-
4
-
-
58149350130
-
Soluble epoxide hydrolase inhibitors reduce the development of atherosclerosis in apolipoprotein e-knockout mouse model
-
This is the first article to demonstrate the antiatherosclerotic effects of sEH inhibitors and correlation of these effects with plasma epoxide to diol levels
-
Ulu A, Davis BB, Tsai HJ, et al.: Soluble epoxide hydrolase inhibitors reduce the development of atherosclerosis in apolipoprotein e-knockout mouse model. J Cardiovasc Pharmacol 2008, 52:314-323. This is the first article to demonstrate the antiatherosclerotic effects of sEH inhibitors and correlation of these effects with plasma epoxide to diol levels.
-
(2008)
J Cardiovasc Pharmacol
, vol.52
, pp. 314-323
-
-
Ulu, A.1
Davis, B.B.2
Tsai, H.J.3
-
5
-
-
0030973315
-
Epoxyeicosatrienoic acids activate K+ channels in coronary smooth muscle through a guanine nucleotide binding protein
-
Li PL, Campbell WB: Epoxyeicosatrienoic acids activate K+ channels in coronary smooth muscle through a guanine nucleotide binding protein. Circ Res 1997, 80:877-884.
-
(1997)
Circ Res
, vol.80
, pp. 877-884
-
-
Li, P.L.1
Campbell, W.B.2
-
6
-
-
1542722060
-
Cytochrome P450 epoxygenases as EDHF synthase (s)
-
Fleming I: Cytochrome P450 epoxygenases as EDHF synthase (s). Pharmacol Res 2004, 49:525-533.
-
(2004)
Pharmacol Res
, vol.49
, pp. 525-533
-
-
Fleming, I.1
-
7
-
-
33644654633
-
An orally active epoxide hydrolase inhibitor lowers blood pressure and provides renal protection in salt-sensitive hypertension
-
Imig JD, Zhao X, Zaharis CZ, Olearczyk JJ, Pollock DM, Newman JW, Kim IH, Watanabe T, Hammock BD: An orally active epoxide hydrolase inhibitor lowers blood pressure and provides renal protection in salt-sensitive hypertension. Hypertension 2005, 46:975-981.
-
(2005)
Hypertension
, vol.46
, pp. 975-981
-
-
Imig, J.D.1
Zhao, X.2
Zaharis, C.Z.3
Olearczyk, J.J.4
Pollock, D.M.5
Newman, J.W.6
Kim, I.H.7
Watanabe, T.8
Hammock, B.D.9
-
8
-
-
0035955607
-
Cytochrome p450 and vascular homeostasis
-
Fleming I: Cytochrome p450 and vascular homeostasis. Circ Res 2001, 89:753-762.
-
(2001)
Circ Res
, vol.89
, pp. 753-762
-
-
Fleming, I.1
-
9
-
-
0033529767
-
Potent urea and carbamate inhibitors of soluble epoxide hydrolases
-
Morisseau C, Goodrow MH, Dowdy D, et al.: Potent urea and carbamate inhibitors of soluble epoxide hydrolases. Proc Natl Acad Sci U S A 1999, 96:8849-8854.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 8849-8854
-
-
Morisseau, C.1
Goodrow, M.H.2
Dowdy, D.3
-
10
-
-
0033588034
-
Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids
-
Node K, Huo Y, Ruan X, et al.: Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids. Science 1999, 285:1276-1279.
-
(1999)
Science
, vol.285
, pp. 1276-1279
-
-
Node, K.1
Huo, Y.2
Ruan, X.3
-
11
-
-
13844316739
-
Epoxide hydrolases: Mechanisms, inhibitor designs, and biological roles
-
Morisseau C, Hammock BD: Epoxide hydrolases: mechanisms, inhibitor designs, and biological roles. Annu Rev Pharmacol Toxicol 2005, 45:311-333.
-
(2005)
Annu Rev Pharmacol Toxicol
, vol.45
, pp. 311-333
-
-
Morisseau, C.1
Hammock, B.D.2
-
12
-
-
22244443733
-
Soluble epoxide hydrolase is a therapeutic target for acute inflammation
-
Schmelzer KR, Kubala L, Newman JW, et al.: Soluble epoxide hydrolase is a therapeutic target for acute inflammation. Proc Natl Acad Sci U S A 2005, 102:9772-9777.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 9772-9777
-
-
Schmelzer, K.R.1
Kubala, L.2
Newman, J.W.3
-
13
-
-
34548755151
-
The soluble epoxide hydrolase as a pharmaceutical target for hypertension
-
Chiamvimonvat N, Ho CM, Tsai HJ, Hammock BD: The soluble epoxide hydrolase as a pharmaceutical target for hypertension. J Cardiovasc Pharmacol 2007, 50:225-237.
-
(2007)
J Cardiovasc Pharmacol
, vol.50
, pp. 225-237
-
-
Chiamvimonvat, N.1
Ho, C.M.2
Tsai, H.J.3
Hammock, B.D.4
-
14
-
-
0034711488
-
Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids
-
Yu Z, Xu F, Huse LM, et al.: Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids. Circ Res 2000, 87:992-998.
-
(2000)
Circ Res
, vol.87
, pp. 992-998
-
-
Yu, Z.1
Xu, F.2
Huse, L.M.3
-
15
-
-
15744382006
-
Soluble epoxide hydrolase is a main effector of angiotensin II-induced hypertension
-
Jung O, Brandes RP, Kim IH, Soluble epoxide hydrolase is a main effector of angiotensin II-induced hypertension. Hypertension 2005, 45:759-765.
-
(2005)
Hypertension
, vol.45
, pp. 759-765
-
-
Jung, O.1
Brandes, R.P.2
Kim, I.H.3
-
16
-
-
58849115391
-
Soluble epoxide hydrolase plays an essential role in angiotensin II-induced cardiac hypertrophy
-
Ai D, Pang W, Li N, et al.: Soluble epoxide hydrolase plays an essential role in angiotensin II-induced cardiac hypertrophy. Proc Natl Acad Sci U S A 2009, 106:564-569.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 564-569
-
-
Ai, D.1
Pang, W.2
Li, N.3
-
17
-
-
33750529521
-
Inhibition of soluble epoxide hydrolase reduces LPS-induced thermal hyperalgesia and mechanical allodynia in a rat model of inflammatory pain
-
Inceoglu B, Jinks SL, Schmelzer KR, et al.: Inhibition of soluble epoxide hydrolase reduces LPS-induced thermal hyperalgesia and mechanical allodynia in a rat model of inflammatory pain. Life Sci 2006, 79:2311-2319.
-
(2006)
Life Sci
, vol.79
, pp. 2311-2319
-
-
Inceoglu, B.1
Jinks, S.L.2
Schmelzer, K.R.3
-
18
-
-
34347407952
-
Soluble epoxide hydrolase: A novel therapeutic target in stroke
-
Zhang W, Koerner IP, Noppens R, et al.: Soluble epoxide hydrolase: a novel therapeutic target in stroke. J Cereb Blood Flow Metab 2007, 27:1931-1940.
-
(2007)
J Cereb Blood Flow Metab
, vol.27
, pp. 1931-1940
-
-
Zhang, W.1
Koerner, I.P.2
Noppens, R.3
-
19
-
-
17444380409
-
Association of soluble epoxide hydrolase gene polymorphism with insulin resistance in type 2 diabetic patients
-
Ohtoshi K, Kaneto H, Node K, et al.: Association of soluble epoxide hydrolase gene polymorphism with insulin resistance in type 2 diabetic patients. Biochem Biophys Res Commun 2005, 331:347-350.
-
(2005)
Biochem Biophys Res Commun
, vol.331
, pp. 347-350
-
-
Ohtoshi, K.1
Kaneto, H.2
Node, K.3
-
20
-
-
57749091900
-
Soluble epoxide hydrolase and epoxyeicosatrienoic acids modulate two distinct analgesic pathways
-
Inceoglu B, Jinks SL, Ulu A, et al.: Soluble epoxide hydrolase and epoxyeicosatrienoic acids modulate two distinct analgesic pathways. Proc Natl Acad Sci U S A 2008, 105:18901-18906.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 18901-18906
-
-
Inceoglu, B.1
Jinks, S.L.2
Ulu, A.3
-
21
-
-
34547468357
-
Angiotensin II up-regulates soluble epoxide hydrolase in vascular endothelium in vitro and in vivo
-
Ai D, Fu Y, Guo D, et al.: Angiotensin II up-regulates soluble epoxide hydrolase in vascular endothelium in vitro and in vivo. Proc Natl Acad Sci U S A 2007, 104:9018-9023.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 9018-9023
-
-
Ai, D.1
Fu, Y.2
Guo, D.3
-
22
-
-
33845474465
-
Prevention and reversal of cardiac hypertrophy by soluble epoxide hydrolase inhibitors
-
Xu D, Li N, He Y, et al.: Prevention and reversal of cardiac hypertrophy by soluble epoxide hydrolase inhibitors. Proc Natl Acad Sci U S A 2006, 103:18733-18738.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 18733-18738
-
-
Xu, D.1
Li, N.2
He, Y.3
-
23
-
-
70350604449
-
Beneficial effects of soluble epoxide hydrolase inhibitors in myocardial infarction model: Insight gained using metabolomic approaches
-
Li N, Liu JY, Timofeyev V, et al.: Beneficial effects of soluble epoxide hydrolase inhibitors in myocardial infarction model: Insight gained using metabolomic approaches. J Mol Cell Cardiol 2009, 47:835-845.
-
(2009)
J Mol Cell Cardiol
, vol.47
, pp. 835-845
-
-
Li, N.1
Liu, J.Y.2
Timofeyev, V.3
-
24
-
-
60549106716
-
Administration of a substituted adamantyl urea inhibitor of soluble epoxide hydrolase protects the kidney from damage in hypertensive Goto-Kakizaki rats
-
Olearczyk JJ, Quigley JE, Mitchell BC, et al.: Administration of a substituted adamantyl urea inhibitor of soluble epoxide hydrolase protects the kidney from damage in hypertensive Goto-Kakizaki rats. Clin Sci (Lond) 2009, 116:61-70.
-
(2009)
Clin Sci (Lond)
, vol.116
, pp. 61-70
-
-
Olearczyk, J.J.1
Quigley, J.E.2
Mitchell, B.C.3
-
25
-
-
33644697099
-
An epoxide hydrolase inhibitor, 12-(3-adamantan-1-yl-ureido)dodecanoic acid (AUDA), reduces ischemic cerebral infarct size in strokeprone spontaneously hypertensive rats
-
Dorrance AM, Rupp N, Pollock DM, et al.: An epoxide hydrolase inhibitor, 12-(3-adamantan-1-yl-ureido)dodecanoic acid (AUDA), reduces ischemic cerebral infarct size in strokeprone spontaneously hypertensive rats. J Cardiovasc Pharmacol 2005, 46:842-848.
-
(2005)
J Cardiovasc Pharmacol
, vol.46
, pp. 842-848
-
-
Dorrance, A.M.1
Rupp, N.2
Pollock, D.M.3
-
26
-
-
0036790708
-
Polymorphism in soluble epoxide hydrolase and blood pressure in spontaneously hypertensive rats
-
Fornage M, Hinojos CA, Nurowska BW, et al.: Polymorphism in soluble epoxide hydrolase and blood pressure in spontaneously hypertensive rats. Hypertension 2002, 40:485-490.
-
(2002)
Hypertension
, vol.40
, pp. 485-490
-
-
Fornage, M.1
Hinojos, C.A.2
Nurowska, B.W.3
-
27
-
-
20844452556
-
Risk of coronary artery disease associated with polymorphism of the cytochrome P450 epoxygenase CYP2J2
-
Spiecker M, Darius H, Hankeln T, et al.: Risk of coronary artery disease associated with polymorphism of the cytochrome P450 epoxygenase CYP2J2. Circulation 2004, 110:2132-2136.
-
(2004)
Circulation
, vol.110
, pp. 2132-2136
-
-
Spiecker, M.1
Darius, H.2
Hankeln, T.3
-
28
-
-
33845535114
-
Sequence variation in the soluble epoxide hydrolase gene and subclinical coronary atherosclerosis: Interaction with cigarette smoking
-
Wei Q, Doris PA, Pollizotto MV, et al.: Sequence variation in the soluble epoxide hydrolase gene and subclinical coronary atherosclerosis: interaction with cigarette smoking. Atherosclerosis 2007, 190:26-34.
-
(2007)
Atherosclerosis
, vol.190
, pp. 26-34
-
-
Wei, Q.1
Doris, P.A.2
Pollizotto, M.V.3
-
29
-
-
21244457581
-
Tobacco smoke dysregulates endothelial vasoregulatory transcripts in vivo
-
Maresh JG, Xu H, Jiang N, et al.: Tobacco smoke dysregulates endothelial vasoregulatory transcripts in vivo. Physiol Genomics 2005, 21:308-313.
-
(2005)
Physiol Genomics
, vol.21
, pp. 308-313
-
-
Maresh, J.G.1
Xu, H.2
Jiang, N.3
-
30
-
-
33745222033
-
Genetic variation in soluble epoxide hydrolase (EPHX2) and risk of coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) study
-
Lee CR, North KE, Bray MS, et al.: Genetic variation in soluble epoxide hydrolase (EPHX2) and risk of coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) study. Hum Mol Genet 2006, 15:1640-1649.
-
(2006)
Hum Mol Genet
, vol.15
, pp. 1640-1649
-
-
Lee, C.R.1
North, K.E.2
Bray, M.S.3
-
31
-
-
10744225519
-
Soluble epoxide hydrolase variant (Glu287Arg) modifies plasma total cholesterol and triglyceride phenotype in familial hypercholesterolemia: Intrafamilial association study in an eight-generation hyperlipidemic kindred
-
Sato K, Emi M, Ezura Y, et al.: Soluble epoxide hydrolase variant (Glu287Arg) modifies plasma total cholesterol and triglyceride phenotype in familial hypercholesterolemia: intrafamilial association study in an eight-generation hyperlipidemic kindred. J Hum Genet 2004, 49:29-34.
-
(2004)
J Hum Genet
, vol.49
, pp. 29-34
-
-
Sato, K.1
Emi, M.2
Ezura, Y.3
-
32
-
-
38549111871
-
Altered soluble epoxide hydrolase gene expression and function and vascular disease risk in the stroke-prone spontaneously hypertensive rat
-
Corenblum MJ, Wise VE, Georgi K, et al.: Altered soluble epoxide hydrolase gene expression and function and vascular disease risk in the stroke-prone spontaneously hypertensive rat. Hypertension 2008, 51:567-573.
-
(2008)
Hypertension
, vol.51
, pp. 567-573
-
-
Corenblum, M.J.1
Wise, V.E.2
Georgi, K.3
-
33
-
-
25844438367
-
The Prevalence of CYP2C8, 2C9, 2J2, and soluble epoxide hydrolase polymorphisms in African Americans with hypertension
-
Dreisbach AW, Japa S, Sigel A, et al.: The Prevalence of CYP2C8, 2C9, 2J2, and soluble epoxide hydrolase polymorphisms in African Americans with hypertension. Am J Hypertens 2005, 18:1276-1281.
-
(2005)
Am J Hypertens
, vol.18
, pp. 1276-1281
-
-
Dreisbach, A.W.1
Japa, S.2
Sigel, A.3
-
34
-
-
1642458135
-
Polymorphism of the soluble epoxide hydrolase is associated with coronary artery calcification in African-American subjects: The coronary artery risk development in young adults (CARDIA) study
-
Fornage M, Boerwinkle E, Doris PA, et al.: Polymorphism of the soluble epoxide hydrolase is associated with coronary artery calcification in African-American subjects: the Coronary Artery Risk Development in Young Adults (CARDIA) study. Circulation 2004, 109:335-339.
-
(2004)
Circulation
, vol.109
, pp. 335-339
-
-
Fornage, M.1
Boerwinkle, E.2
Doris, P.A.3
-
35
-
-
26444506849
-
The soluble epoxide hydrolase gene harbors sequence variation associated with susceptibility to and protection from incident ischemic stroke
-
Fornage M, Lee CR, Doris PA, et al.: The soluble epoxide hydrolase gene harbors sequence variation associated with susceptibility to and protection from incident ischemic stroke. Hum Mol Genet 2005, 14:2829-2837.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 2829-2837
-
-
Fornage, M.1
Lee, C.R.2
Doris, P.A.3
-
37
-
-
33846433034
-
Angiotensin II-induced aortic aneurysms
-
Edited by Xu Q. Chichester, England: Life and Medical Sciences, John Wiley & Sons
-
Wang YX, Cassis LA: Angiotensin II-induced aortic aneurysms. In A Handbook of Mouse Models for Cardiovascular Diseases. Edited by Xu Q. Chichester, England: Life and Medical Sciences, John Wiley & Sons; 2006:125-136.
-
(2006)
A Handbook of Mouse Models for Cardiovascular Diseases
, pp. 125-136
-
-
Wang, Y.X.1
Cassis, L.A.2
-
38
-
-
34447264052
-
Monocyte chemoattractant protein-1 or macrophage inflammatory protein-1alpha deficiency does not affect angiotensin IIinduced intimal hyperplasia in carotid artery ligation model
-
Zhang LN, da Cunha V, Martin-McNulty B, et al.: Monocyte chemoattractant protein-1 or macrophage inflammatory protein-1alpha deficiency does not affect angiotensin IIinduced intimal hyperplasia in carotid artery ligation model. Cardiovasc Pathol 2007, 16:231-236.
-
(2007)
Cardiovasc Pathol
, vol.16
, pp. 231-236
-
-
Zhang, L.N.1
Da Cunha, V.2
Martin-McNulty, B.3
-
39
-
-
43249113686
-
Mechanisms of intimal hyperplasia learned from a murine carotid artery ligation model
-
This review article discussed a mouse model of carotid artery ligation-induced vascular remodeling used in the cited study
-
Zhang LN, Parkinson JF, Haskell C, Wang YX: Mechanisms of intimal hyperplasia learned from a murine carotid artery ligation model. Curr Vasc Pharmacol 2008, 6:37-43. This review article discussed a mouse model of carotid artery ligation-induced vascular remodeling used in the cited study.
-
(2008)
Curr Vasc Pharmacol
, vol.6
, pp. 37-43
-
-
Zhang, L.N.1
Parkinson, J.F.2
Haskell, C.3
Wang, Y.X.4
-
40
-
-
39449112172
-
Interferon-beta attenuates angiotensin II-accelerated atherosclerosis and vascular remodeling in apolipoprotein E deficient mice
-
Zhang LN, Velichko S, Vincelette J, et al.: Interferon-beta attenuates angiotensin II-accelerated atherosclerosis and vascular remodeling in apolipoprotein E deficient mice. Atherosclerosis 2008, 197:204-211.
-
(2008)
Atherosclerosis
, vol.197
, pp. 204-211
-
-
Zhang, L.N.1
Velichko, S.2
Vincelette, J.3
-
41
-
-
33646715317
-
Endothelial NO synthase deficiency promotes smooth muscle progenitor cells in association with upregulation of stromal cell-derived factor- 1alpha in a mouse model of carotid artery ligation
-
Zhang LN, Wilson DW, da Cunha V, et al.: Endothelial NO synthase deficiency promotes smooth muscle progenitor cells in association with upregulation of stromal cell-derived factor- 1alpha in a mouse model of carotid artery ligation. Arterioscler Thromb Vasc Biol 2006, 26:765-772.
-
(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, pp. 765-772
-
-
Zhang, L.N.1
Wilson, D.W.2
Da Cunha, V.3
-
43
-
-
0033984125
-
The evolving role of statins in the management of atherosclerosis
-
Vaughan CJ, Gotto AM Jr, Basson CT: The evolving role of statins in the management of atherosclerosis. J Am Coll Cardiol 2000, 35:1-10.
-
(2000)
J Am Coll Cardiol
, vol.35
, pp. 1-10
-
-
Vaughan, C.J.1
Gotto Jr., A.M.2
Basson, C.T.3
-
44
-
-
61349115586
-
Opposite regulation of cholesterol levels by the phosphatase and hydrolase domains of soluble epoxide hydrolase
-
EnayetAllah AE, Luria A, Luo B, et al.: Opposite regulation of cholesterol levels by the phosphatase and hydrolase domains of soluble epoxide hydrolase. J Biol Chem 2008, 283:36592-36598.
-
(2008)
J Biol Chem
, vol.283
, pp. 36592-36598
-
-
EnayetAllah, A.E.1
Luria, A.2
Luo, B.3
-
45
-
-
33751198051
-
Abdominal aortic aneurysm: Pathogenesis and implications for management
-
Golledge J, Muller J, Daugherty A, Norman P: Abdominal aortic aneurysm: pathogenesis and implications for management. Arterioscler Thromb Vasc Biol 2006, 26:2605-2613.
-
(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, pp. 2605-2613
-
-
Golledge, J.1
Muller, J.2
Daugherty, A.3
Norman, P.4
-
47
-
-
0032693599
-
Atherosclerosis is an inflammatory disease
-
Ross R: Atherosclerosis is an inflammatory disease. Am Heart J 1999, 138(5 Pt 2):S419-S420.
-
(1999)
Am Heart J
, vol.138
, Issue.5 PART 2
-
-
Ross, R.1
-
48
-
-
0012614193
-
Mechanisms of abdominal aortic aneurysm formation
-
Daugherty A, Cassis LA: Mechanisms of abdominal aortic aneurysm formation. Curr Atheroscler Rep 2002, 4:222-227.
-
(2002)
Curr Atheroscler Rep
, vol.4
, pp. 222-227
-
-
Daugherty, A.1
Cassis, L.A.2
-
49
-
-
10744224870
-
17 Betaestradiol attenuates development of angiotensin II-induced aortic abdominal aneurysm in apolipoprotein E-deficient mice
-
Martin-McNulty B, Tham DM, da Cunha V, et al.: 17 Betaestradiol attenuates development of angiotensin II-induced aortic abdominal aneurysm in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol 2003, 23:1627-1632.
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 1627-1632
-
-
Martin-McNulty, B.1
Tham, D.M.2
Da Cunha, V.3
-
50
-
-
0037009883
-
Angiotensin II is associated with activation of NF-kappaB-mediated genes and downregulation of PPARs
-
Tham DM, Martin-McNulty B, Wang YX, et al.: Angiotensin II is associated with activation of NF-kappaB-mediated genes and downregulation of PPARs. Physiol Genomics 2002, 11:21-30.
-
(2002)
Physiol Genomics
, vol.11
, pp. 21-30
-
-
Tham, D.M.1
Martin-McNulty, B.2
Wang, Y.X.3
-
51
-
-
0034790633
-
Angiotensin II increases urokinase-type plasminogen activator expression and induces aneurysm in the abdominal aorta of apolipoprotein E-deficient mice
-
Wang YX, Martin-McNulty B, Freay AD, et al.: Angiotensin II increases urokinase-type plasminogen activator expression and induces aneurysm in the abdominal aorta of apolipoprotein E-deficient mice. Am J Pathol 2001, 159:1455-1464.
-
(2001)
Am J Pathol
, vol.159
, pp. 1455-1464
-
-
Wang, Y.X.1
Martin-McNulty, B.2
Freay, A.D.3
-
53
-
-
33645891172
-
Cytokines in atherosclerosis: Pathogenic and regulatory pathways
-
Tedgui A, Mallat Z: Cytokines in atherosclerosis: pathogenic and regulatory pathways. Physiol Rev 2006, 86:515-581.
-
(2006)
Physiol Rev
, vol.86
, pp. 515-581
-
-
Tedgui, A.1
Mallat, Z.2
-
54
-
-
0035805539
-
Pathways of epoxyeicosatrienoic acid metabolism in endothelial cells. Implications for the vascular effects of soluble epoxide hydrolase inhibition
-
Fang X, Kaduce TL, Weintraub NL, et al.: Pathways of epoxyeicosatrienoic acid metabolism in endothelial cells. Implications for the vascular effects of soluble epoxide hydrolase inhibition. J Biol Chem 2001, 276:14867-14874.
-
(2001)
J Biol Chem
, vol.276
, pp. 14867-14874
-
-
Fang, X.1
Kaduce, T.L.2
Weintraub, N.L.3
-
55
-
-
0036889533
-
Human coronary endothelial cells convert 14,15-EET to a biologically active chain-shortened epoxide
-
Fang X, Weintraub NL, Oltman CL, et al.: Human coronary endothelial cells convert 14,15-EET to a biologically active chain-shortened epoxide. Am J Physiol Heart Circ Physiol 2002, 283:H2306-2314.
-
(2002)
Am J Physiol Heart Circ Physiol
, vol.283
-
-
Fang, X.1
Weintraub, N.L.2
Oltman, C.L.3
-
56
-
-
36048979880
-
Vascular adhesion molecules in atherosclerosis
-
Galkina E, Ley K: Vascular adhesion molecules in atherosclerosis. Arterioscler Thromb Vasc Biol 2007, 27:2292-2301.
-
(2007)
Arterioscler Thromb Vasc Biol
, vol.27
, pp. 2292-2301
-
-
Galkina, E.1
Ley, K.2
-
57
-
-
0037123925
-
Inhibition of vascular smooth muscle cell migration by cytochrome p450 epoxygenasederived eicosanoids
-
Sun J, Sui X, Bradbury JA, et al.: Inhibition of vascular smooth muscle cell migration by cytochrome p450 epoxygenasederived eicosanoids. Circ Res 2002, 90:1020-1027.
-
(2002)
Circ Res
, vol.90
, pp. 1020-1027
-
-
Sun, J.1
Sui, X.2
Bradbury, J.A.3
-
58
-
-
0037133175
-
Inhibitors of soluble epoxide hydrolase attenuate vascular smooth muscle cell proliferation
-
Davis BB, Thompson DA, Howard LL, et al.: Inhibitors of soluble epoxide hydrolase attenuate vascular smooth muscle cell proliferation. Proc Natl Acad Sci U S A 2002, 99:2222-2227.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 2222-2227
-
-
Davis, B.B.1
Thompson, D.A.2
Howard, L.L.3
-
59
-
-
31144468654
-
Attenuation of vascular smooth muscle cell proliferation by 1-cyclohexyl-3- dodecyl urea is independent of soluble epoxide hydrolase inhibition
-
Davis BB, Morisseau C, Newman JW, et al.: Attenuation of vascular smooth muscle cell proliferation by 1-cyclohexyl-3- dodecyl urea is independent of soluble epoxide hydrolase inhibition. J Pharmacol Exp Ther 2006, 316:815-821.
-
(2006)
J Pharmacol Exp Ther
, vol.316
, pp. 815-821
-
-
Davis, B.B.1
Morisseau, C.2
Newman, J.W.3
-
60
-
-
67049119782
-
Soluble epoxide inhibition is protective against cerebral ischemia via vascular and neural protection
-
Simpkins AN, Rudic RD, Schreihofer DA, et al.: Soluble epoxide inhibition is protective against cerebral ischemia via vascular and neural protection. Am J Pathol 2009, 174:2086-2095.
-
(2009)
Am J Pathol
, vol.174
, pp. 2086-2095
-
-
Simpkins, A.N.1
Rudic, R.D.2
Schreihofer, D.A.3
-
61
-
-
70449640639
-
Variation in the human soluble epoxide hydrolase gene and risk of restenosis after percutaneous coronary intervention
-
Kullmann S, Binner P, Rackebrandt K, et al.: Variation in the human soluble epoxide hydrolase gene and risk of restenosis after percutaneous coronary intervention. BMC Cardiovasc Disord 2009, 9:48.
-
(2009)
BMC Cardiovasc Disord
, vol.9
, pp. 48
-
-
Kullmann, S.1
Binner, P.2
Rackebrandt, K.3
-
62
-
-
70349636047
-
Soluble epoxide hydrolase as a therapeutic target for cardiovascular diseases
-
This is the most recent review article on sEH as a novel therapeutic target for cardiovascular disease
-
Imig JD, Hammock BD: Soluble epoxide hydrolase as a therapeutic target for cardiovascular diseases. Nat Rev Drug Discov 2009, 8:794-805. This is the most recent review article on sEH as a novel therapeutic target for cardiovascular disease.
-
(2009)
Nat Rev Drug Discov
, vol.8
, pp. 794-805
-
-
Imig, J.D.1
Hammock, B.D.2
-
63
-
-
33748363508
-
Augmentation of myocardial production of 15-epi-lipoxin-a4 by pioglitazone and atorvastatin in the rat
-
Birnbaum Y, Ye Y, Lin Y, et al.: Augmentation of myocardial production of 15-epi-lipoxin-a4 by pioglitazone and atorvastatin in the rat. Circulation 2006, 114:929-935.
-
(2006)
Circulation
, vol.114
, pp. 929-935
-
-
Birnbaum, Y.1
Ye, Y.2
Lin, Y.3
-
64
-
-
33748363509
-
Myocardial 15-epi-lipoxin A4 generation provides a new mechanism for the immunomodulatory effects of statins and thiazolidinediones
-
Levy BD: Myocardial 15-epi-lipoxin A4 generation provides a new mechanism for the immunomodulatory effects of statins and thiazolidinediones. Circulation 2006, 114:873-875.
-
(2006)
Circulation
, vol.114
, pp. 873-875
-
-
Levy, B.D.1
-
65
-
-
77951448295
-
Lovastatin decreases acute mucosal inflammation via 15-epi-lipoxin A(4)
-
(in press)
-
Planaguma A, Pfeffer MA, Rubin G, et al.: Lovastatin decreases acute mucosal inflammation via 15-epi-lipoxin A(4). Mucosal Immunol 2010 (in press).
-
(2010)
Mucosal Immunol
-
-
Planaguma, A.1
Pfeffer, M.A.2
Rubin, G.3
-
66
-
-
74149087378
-
Inhibition of soluble epoxide hydrolase enhances the anti-inflammatory effects of aspirin and 5-lipoxygenase activation protein inhibitor in a murine model
-
Liu JY, Yang J, Inceoglu B, et al.: Inhibition of soluble epoxide hydrolase enhances the anti-inflammatory effects of aspirin and 5-lipoxygenase activation protein inhibitor in a murine model. Biochem Pharmacol 2010, 79:880-887.
-
Biochem Pharmacol
, vol.2010
, Issue.79
, pp. 880-887
-
-
Liu, J.Y.1
Yang, J.2
Inceoglu, B.3
-
67
-
-
77249096825
-
Expression and regulation of soluble epoxide hydrolase in adipose tissue
-
De Taeye BM, Morisseau C, Coyle J, et al.: Expression and regulation of soluble epoxide hydrolase in adipose tissue. Obesity (Silver Spring) 2010, 18:489-498.
-
Obesity (Silver Spring)
, vol.2010
, Issue.18
, pp. 489-498
-
-
De Taeye, B.M.1
Morisseau, C.2
Coyle, J.3
-
68
-
-
47049120789
-
An essential role for SRC-activated STAT-3 in 14,15-EET-induced VEGF expression and angiogenesis
-
Cheranov SY, Karpurapu M, Wang D, et al.: An essential role for SRC-activated STAT-3 in 14,15-EET-induced VEGF expression and angiogenesis. Blood 2008, 111:5581-5591.
-
(2008)
Blood
, vol.111
, pp. 5581-5591
-
-
Cheranov, S.Y.1
Karpurapu, M.2
Wang, D.3
-
69
-
-
33644684217
-
Preclinical and clinical development of the oral multikinase inhibitor sorafenib in cancer treatment
-
Strumberg D: Preclinical and clinical development of the oral multikinase inhibitor sorafenib in cancer treatment. Drugs Today (Barc) 2005, 41:773-784.
-
(2005)
Drugs Today (Barc)
, vol.41
, pp. 773-784
-
-
Strumberg, D.1
-
70
-
-
69049113954
-
Discovery of a highly potent, selective, and bioavailable soluble epoxide hydrolase inhibitor with excellent ex vivo target engagement
-
Shen HC, Ding F-X, Wang S, et al.: Discovery of a highly potent, selective, and bioavailable soluble epoxide hydrolase inhibitor with excellent ex vivo target engagement. J Med Chem 2009, 52:5009-5012.
-
(2009)
J Med Chem
, vol.52
, pp. 5009-5012
-
-
Shen, H.C.1
Ding, F.-X.2
Wang, S.3
|