Valid μ finite element models of vertebral trabecular bone can be obtained using tissue properties measured with nanoindentation under wet conditions

Journal of Biomechanics

Volumn 43, Issue 9, 2010, Pages 1731-1737

  Wolfram, Uwe ^a   Wilke, Hans Joachim ^a   Zysset, Philippe K ^b  

^a UNIVERSITY OF ULM   (Germany)

^b VIENNA UNIVERSITY OF TECHNOLOGY   (Austria)

Author keywords

Finite element; Material properties; Micro CT; Nanoindentation; Trabecular bone

Indexed keywords

CONTINUUM LEVEL; CORRELATION COEFFICIENT; CT SCAN; DRY AND WET; EFFECTIVE PROPERTY; FE MODEL; FE-SIMULATION; FINITE ELEMENT; FINITE ELEMENT MODELS; FINITE ELEMENT SIMULATIONS; LINEAR ELASTIC; MACROSCOPIC MATERIALS; MATERIAL PROPERTIES; MECHANICAL COMPRESSION; MICRO CT; MOIST CONDITIONS; NON DESTRUCTIVE; PUBLIC HEALTH; SURGICAL INTERVENTIONS; TENSION AND COMPRESSION; TESTING CONDITIONS; TISSUE MODULUS; TISSUE PROPERTIES; TORSION TESTS; TRABECULAR BONES; VERTEBRAL FRACTURES; VERTEBRAL TRABECULAR BONE; VERTEBROPLASTY; WET CONDITIONS; WET TISSUES;

BONE; COMPUTERIZED TOMOGRAPHY; EXPERIMENTS; FRACTURE; HEALTH RISKS; MATERIALS PROPERTIES; NANOINDENTATION; TORSION TESTING; TORSIONAL STRESS;

FINITE ELEMENT METHOD;

ADULT; AGED; ARTICLE; BIOMECHANICS; BONE TISSUE; COMPRESSIVE STRENGTH; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; FEMALE; FINITE ELEMENT ANALYSIS; HUMAN; HUMAN TISSUE; INTERMETHOD COMPARISON; MALE; MECHANICAL TORSION; MOISTURE; NANOANALYSIS; PRIORITY JOURNAL; STATISTICAL MODEL; TISSUE SPECIFICITY; TRABECULAR BONE; VALIDATION STUDY; VERTEBRA; YOUNG MODULUS; BIOLOGICAL MODEL; COMPUTER SIMULATION; HARDNESS; IN VITRO STUDY; INSTRUMENTATION; LUMBAR VERTEBRA; MECHANICAL STRESS; METHODOLOGY; MIDDLE AGED; NANOTECHNOLOGY; PHYSIOLOGY; WETTABILITY;

ADULT; AGED; AGED, 80 AND OVER; COMPRESSIVE STRENGTH; COMPUTER SIMULATION; ELASTIC MODULUS; FEMALE; FINITE ELEMENT ANALYSIS; HARDNESS TESTS; HUMANS; LUMBAR VERTEBRAE; MALE; MIDDLE AGED; MODELS, BIOLOGICAL; NANOTECHNOLOGY; STRESS, MECHANICAL; THORACIC VERTEBRAE; WETTABILITY;

EID: 77953536589     PISSN: 00219290     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiomech.2010.02.026     Document Type: Article

References (37)

1. Arbenz P., van Lenthe G., Mennel U., Müller R., Sala M. A scalable multi-level preconditioner for matrix-free γ-finite element analysis of human bone structures. International Journal of Numerical Methods in Engineering 2008, 73(7):927-947.
2. Bayraktar H.H., Gupta A., Kwon R.Y., Papadopoulos P., Keaveny T.M. The modified super-ellipsoid yield criterion for human trabecular bone. Journal of Biomechanical Engineering 2004, 126(6):677-684.
3. Bayraktar H.H., Morgan E.F., Niebur G.L., Morris G.E., Wong E.K., Keaveny T.M. Comparison of the elastic and yield properties of human femoral trabecular and cortical bone tissue. Journal of Biomechanics 2004, 37(1):27-35.
4. Bevill G., Eswaran S.K., Farahmand F., Keaveny T.M. The influence of boundary conditions and loading mode on high-resolution finite element-computed trabecular tissue properties. Bone 2009, 44(4):573-578.
5. Bevill G., Keaveny T.M. Trabecular bone strength predictions using finite element analysis of micro-scale images at limited spatial resolution. Bone 2009, 44(4):579-584.
6. Bland J.M., Altman D.G. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986, 1(8476):307-310.
7. Bushby A.J., Ferguson V.L., Boyde A. Nanoindentation of bone: comparison of specimens tested in liquid and embedded in polymethylmethacrylate. Journal of Materials Research 2004, 19(1):249-259.
8. Chevalier Y., Pahr D., Allmer H., Charlebois M., Zysset P. Validation of a voxel-based FE method for prediction of the uniaxial apparent modulus of human trabecular bone using macroscopic mechanical tests and nanoindentation. Journal of Biomechanics 2007, 40(15):3333-3340.
9. Crawford P.R., Cann C.E., Keaveny T.E. Finite element models predict in-vitro vertebral body compressive strength better than quantitative computed tomography. Bone 2003, 33(4):744-750.
10. Garnier K.B., Dumas R., Rumelhart C., Arlot M.E. Mechanical characterization in shear of human femoral cancellous bone: torsion and shear tests. Medical Engineering & Physics 1999, 21(9):641-649.
11. Haddok S.M., Yeh O.C., Mummaneni P.V., Rosenberg W.S., Keaveny T.M. Similarity in the fatigue behavior of trabecular bone across site and species. Journal of Biomechanics 2004, 37(2):181-187.
12. Hengsberger S., Enstroem J., Peyrin F., Zysset P.K. How is the indentation modulus of bone tissue related to its macroscopic elastic response? A validation study. Journal of Biomechanics 2003, 36(10):1503-1509.
13. Hengsberger S., Kulik A., Zysset P.K. Nanoindentation discriminates the elastic properties of individual human bone lamellae under dry and physiological conditions. Bone 2002, 30(1):178-184.
14. Hoffler C.E., Guo X.E., Zysset P.K., Goldstein S.A. An application of nanoindentation technique to measure bone tissue lamellae properties. Journal of Biomechanical Engineering 2005, 127(7):1046-1053.
15. Hoffler C.E., Moore K.E., Kozloff K., Zysset P.K., Brown M.B., Goldstein S.A. Heterogeneity of bone lamellar-level elastic moduli. Bone 2000, 26(6):603-609.
16. Jähne B. Digital Image Processing 2005, Springer, Berlin, Heidelberg, New York.
17. Keaveny T.M., Pinilla T.P., Crawford R.P., Kopperdahl D.L., Lou A. Systematic and random errors in compression testing of trabecular bone. Journal of Orthopaedic Research 1997, 15(1):101-110.
18. Kopperdahl D.L., Keaveny T.M. Yield strain behaviour of trabecular bone. Journal of Biomechanics 1998, 31(7):601-608.
19. Lewis G., Nyman J.S. The use of nanoindentation for characterizing the properties of mineralized hard tissues: state-of-the art review. Journal of Biomedical Materials Research. Part B, Applied Biomaterials 2008, 288-303(1):87.
20. Lin L.K. A concordance correlation coefficient to evaluate reproducibility. Biometrics 1989, 45(1):255-268.
21. Morgan E.F., Bayraktar H.H., Keaveny T.M. Trabecular bone modulus-density relationships depend on anatomic site. Journal of Biomechanics 2003, 36(7):897-904.
22. Nadai, A., Phelps, R.H. (Eds.), 1950. Torsion of a Round Bar. The Stress-Strain Curve in Shear. 21 McGraw-Hill Book Company, Inc. New York, Toronto and London, pp. 347-352.
23. Niebur G.L., Feldstein M.J., Yuen J.C., Chen T.J., Keaveny T.M. High-resolution finite element models with tissue strength asymmetry accurately predict failure of trabecular bone. Journal of Biomechanics 2000, 33(12):1575-1583.
24. Oliver W., Pharr G. An improved technique for determining hardness and elastic modulus using load and displacement sensing indentation experiments. Journal of Materials Research 1992, 7(6):1564-1583.
25. R Development Core Team, 2008. R: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing, Vienna, Austria, ISBN 3-900051-07-0. http://www.R-project.org.
26. Rao R.D., Singrakhia M.D. Painful osteoporotic vertebral fracture. Journal of Bone and Joint Surgery 2003, 85A(10):2010-2022.
27. Rho J., Tsui T.Y., Pharr G.M. Elastic properties of microstructural components of human bone tissue as measured by nanoindentation. Journal of Biomedical Materials Research 1999, 45(1):48-58.
28. Rho J.-Y., Tsui T.Y., Pharr G.M. Elastic properties of human cortical and trabecular lamellar bone measured by nanoindentation. Biomaterials 1997, 20(18):1325-1330.
29. Rietbergen B.v., Huiskes R., Eckstein F., Rüegsegger P. Trabecular bone tissue strains in the healthy and osteoporotic human femur. Journal of Bone and Minerals Research 2003, 18(10):1781-1788.
30. Rietbergen B.v., Odgaard A., Kabel J., Huiskes R. Direct mechanics assessment of elastic constants of elastic symmetries and properties of trabecular bone architecture. Journal of Biomechanics 1996, 29(12):1653-1657.
31. Rietbergen B.v., Weinans H., Huiskes R., Odgaardt A. A new method to determine trabecular bone elastic properties and loading using micromechanical finite-element models. Journal of Bioimechanics 1995, 28(1):69-81.
32. Rincón-Kohli L., Zysset P. Multi-axial mechanical properties of human trabecular bone rincon. Journal of Biomechanics and Modelling in Mechanobiology 2009, 8(3):195-208.
33. Roy M.E., Rho J., Tsui T.Y., Evans N.D., Pharr G.M. Mechanical and morphological variation of the lumbar vertebral cortical and trabecular bone. Journal of Biomedical Materials Research 1999, 44(2):191-197.
34. Turner C.H., Rho J., Takano Y., Tsui T.Y., Pharr G.M. The elastic properties of trabecular and cortical bone tissues are similar: results from two microscopic measurement techniques. Journal of Biomechanics 1999, 32(4):437-441.
35. Verhulp E., Rietbergen B.V., Müller R., Huiskes R. Micro-finite element simulation of trabecular-bone post-yield behaviour-effects of material model, element size and type. Computer Methods in Biomechanics and Biomedical Engineering 2008, 11(4):389-395.
36. Wolfram U., Wilke H.-J., Zysset P.K. Rehydration of vertebral trabecular bone: influences on its anisotropy, its stiffness and the indentation work with a view to age, gender and vertebral level. Bone 2010, 46(2):348-354.
37. Zysset P.K., Guo E.X., Hoffler E.C., Moore K.E., Goldstein S.A. Elastic modulus and hardness of cortical and trabecular bone lamellae measured by nanoindentation in the human femur. Journal of Biomechanics 1999, 32(10):1005-1012.