메뉴 건너뛰기




Volumn 12, Issue 2, 2010, Pages 181-191

[11C]Gefitinib ([11C]Iressa): Radiosynthesis, In Vitro uptake, and In Vivo imaging of intact murine fibrosarcoma

Author keywords

Carbon 11; Carbon ion radiotherapy; CIRT; Fibrosarcoma; Gefitinib; Iressa; Positron emission tomography

Indexed keywords

CARBON 11; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE; GEFITINIB; CARBON; DIAGNOSTIC AGENT; QUINAZOLINE DERIVATIVE;

EID: 77953534901     PISSN: 15361632     EISSN: 18602002     Source Type: Journal    
DOI: 10.1007/s11307-009-0265-5     Document Type: Article
Times cited : (52)

References (38)
  • 2
    • 7144227965 scopus 로고    scopus 로고
    • Epidermal growth factor receptor (EGFR) and EGFR mutations, function and possible role in clinical trials
    • Voldborg BR, Damstrup L, Spang-Thomsen M, Poulsen HS (1997) Epidermal growth factor receptor (EGFR) and EGFR mutations, function and possible role in clinical trials. Ann Oncol 8:1197-1206
    • (1997) Ann Oncol , vol.8 , pp. 1197-1206
    • Voldborg, B.R.1    Damstrup, L.2    Spang-Thomsen, M.3    Poulsen, H.S.4
  • 3
    • 0036718328 scopus 로고    scopus 로고
    • 4-Anilino-3-quinolinecarbonitriles: An emerging class of kinase inhibitors
    • Boschelli DH (2002) 4-Anilino-3-quinolinecarbonitriles: an emerging class of kinase inhibitors. Curr Top Med Chem 2:1051-1063
    • (2002) Curr Top Med Chem , vol.2 , pp. 1051-1063
    • Boschelli, D.H.1
  • 4
    • 0033757709 scopus 로고    scopus 로고
    • Epidermal growth factor receptor tyrosine kinase as a target for anticancer therapy
    • Raymond E, Faivre S, Armand JP (2000) Epidermal growth factor receptor tyrosine kinase as a target for anticancer therapy. Drugs 60 (suppl 1):15-23
    • (2000) Drugs , vol.60 , Issue.SUPPL. 1 , pp. 15-23
    • Raymond, E.1    Faivre, S.2    Armand, J.P.3
  • 6
    • 0035893560 scopus 로고    scopus 로고
    • Epidermal growth factor receptor (HER1) tyrosine kinase inhibitor ZD1839 (Iressa) inhibits HER2/neu (erbB2)-overexpressing breast cancer cells in vitro and in vivo
    • Moulder SL, Yakes FM, Muthuswamy SK, Bianco R, Simpson JF, Arteaga CL (2001) Epidermal growth factor receptor (HER1) tyrosine kinase inhibitor ZD1839 (Iressa) inhibits HER2/neu (erbB2)-over-expressing breast cancer cells in vitro and in vivo. Cancer Res 61:8887-8895 (Pubitemid 34013905)
    • (2001) Cancer Research , vol.61 , Issue.24 , pp. 8887-8895
    • Moulder, S.L.1    Yakes, F.M.2    Muthuswamy, S.K.3    Bianco, R.4    Simpson, J.F.5    Arteaga, C.L.6
  • 7
    • 0037109014 scopus 로고    scopus 로고
    • ZD1839 (Iressa): An orally active inhibitor of epidermal growth factor signaling with potential for cancer therapy
    • Wakeling AE, Guy SP, Woodburn JR et al (2002) ZD1839 (Iressa): an orally active inhibitor of epidermal growth factor signaling with potential for cancer therapy. Cancer Res 62:5749-5754
    • (2002) Cancer Res , vol.62 , pp. 5749-5754
    • Wakeling, A.E.1    Guy, S.P.2    Woodburn, J.R.3
  • 8
    • 0037388251 scopus 로고    scopus 로고
    • ZD1839, a specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, induces the formation of inactive EGFR/HER2 and EGFR/HER3 heterodimers and prevents heregulin signaling in HER2-overexpressing breast cancer cells
    • Anido J, Matar P, Albanell J et al (2003) ZD1839, a specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, induces the formation of inactive EGFR/HER2 and EGFR/HER3 heterodimers and prevents heregulin signaling in HER2-overexpressing breast cancer cells. Clin Cancer Res 9:1274-1283
    • (2003) Clin Cancer Res , vol.9 , pp. 1274-1283
    • Anido, J.1    Matar, P.2    Albanell, J.3
  • 9
    • 34447498780 scopus 로고    scopus 로고
    • CT perfusion for the monitoring of neoadjuvant chemotherapy and radiation therapy in rectal carcinoma: Initial experience
    • Bellomi M, Petralia G, Sonzogni A, Zampino MG, Rocca A (2007) CT perfusion for the monitoring of neoadjuvant chemotherapy and radiation therapy in rectal carcinoma: initial experience. Radiology 244:486-493
    • (2007) Radiology , vol.244 , pp. 486-493
    • Bellomi, M.1    Petralia, G.2    Sonzogni, A.3    Zampino, M.G.4    Rocca, A.5
  • 11
    • 33746517933 scopus 로고    scopus 로고
    • Use of FDG-PET to monitor response to chemotherapy and radiotherapy in patients with lymphomas
    • Mikhaeel NG (2006) Use of FDG-PET to monitor response to chemotherapy and radiotherapy in patients with lymphomas. Eur J Nucl Med Mol Imaging 33(Suppl 1):22-26
    • (2006) Eur J Nucl Med Mol Imaging , vol.33 , Issue.SUPPL. 1 , pp. 22-26
    • Mikhaeel, N.G.1
  • 12
    • 38449116698 scopus 로고    scopus 로고
    • Monitoring response to radiotherapy in human squamous cell cancer bearing nude mice: Comparison of 2′-deoxy-2′-[18F]fluoro-D-glucose (FDG) and 3′-[18F] fluoro-3′-deoxythymidine (FLT)
    • Molthoff CF, Klabbers BM, Berkhof J et al (2007) Monitoring response to radiotherapy in human squamous cell cancer bearing nude mice: comparison of 2′-deoxy-2′-[18F]fluoro-D-glucose (FDG) and 3′-[18F] fluoro-3′-deoxythymidine (FLT). Mol Imaging Biol 9:340-347
    • (2007) Mol Imaging Biol , vol.9 , pp. 340-347
    • Molthoff, C.F.1    Klabbers, B.M.2    Berkhof, J.3
  • 13
    • 0346037190 scopus 로고    scopus 로고
    • Nuclear medicine imaging to predict response to radiotherapy: A review
    • Van de Wiele C, Lahorte C, Oyen W et al (2003) Nuclear medicine imaging to predict response to radiotherapy: a review. Int J Radiat Oncol Biol Phys 55:5-15
    • (2003) Int J Radiat Oncol Biol Phys , vol.55 , pp. 5-15
    • Van De Wiele, C.1    Lahorte, C.2    Oyen, W.3
  • 14
    • 34748856245 scopus 로고    scopus 로고
    • Use of molecular biomarkers for predicting the response to radiotherapy with or without chemotherapy
    • Riesterer O, Milas L, Ang KK (2007) Use of molecular biomarkers for predicting the response to radiotherapy with or without chemotherapy. J Clin Oncol 25:4075-4083
    • (2007) J Clin Oncol , vol.25 , pp. 4075-4083
    • Riesterer, O.1    Milas, L.2    Ang, K.K.3
  • 15
    • 0037942884 scopus 로고    scopus 로고
    • PET screening of anticancer drugs. A faster route to drug/target evaluations in vivo
    • Fredriksson A, Stone-Elander S (2003) PET screening of anticancer drugs. A faster route to drug/target evaluations in vivo. Methods Mol Med 85:279-294
    • (2003) Methods Mol Med , vol.85 , pp. 279-294
    • Fredriksson, A.1    Stone-Elander, S.2
  • 16
    • 46749137956 scopus 로고    scopus 로고
    • Imaging of cell proliferation: Status and prospects
    • Bading JR, Shields AF (2008) Imaging of cell proliferation: status and prospects. J Nucl Med 49(Suppl 2):64S-80S
    • (2008) J Nucl Med , vol.49 , Issue.SUPPL. 2
    • Bading, J.R.1    Shields, A.F.2
  • 17
    • 33750341469 scopus 로고    scopus 로고
    • Risk factors of late rectal bleeding after carbon ion therapy for prostate cancer
    • Ishikawa H, Tsuji H, Kamada T et al (2006) Risk factors of late rectal bleeding after carbon ion therapy for prostate cancer. Int J Radiat Oncol Biol Phys 66:1084-1091
    • (2006) Int J Radiat Oncol Biol Phys , vol.66 , pp. 1084-1091
    • Ishikawa, H.1    Tsuji, H.2    Kamada, T.3
  • 18
    • 34249042721 scopus 로고    scopus 로고
    • Clinical results of carbon ion radiotherapy at NIRS
    • Tsuji H, Mizoe J, Kamada T et al (2007) Clinical results of carbon ion radiotherapy at NIRS. J Radiat Res 48S:A1-A13
    • (2007) J Radiat Res , vol.48 S
    • Tsuji, H.1    Mizoe, J.2    Kamada, T.3
  • 19
    • 61449102735 scopus 로고    scopus 로고
    • Carbon ion radiotherapy for elderly patients 80 years and older with stage I non-small cell lung cancer
    • Sugane T, Baba M, Imai R et al (2009) Carbon ion radiotherapy for elderly patients 80 years and older with stage I non-small cell lung cancer. Lung Cancer 64:45-50
    • (2009) Lung Cancer , vol.64 , pp. 45-50
    • Sugane, T.1    Baba, M.2    Imai, R.3
  • 20
    • 11144356204 scopus 로고    scopus 로고
    • 11C]Methionine positron emission tomography and survival in patients with bone and soft tissue sarcomas treated by carbon ion radiotherapy
    • 11C]Methionine positron emission tomography and survival in patients with bone and soft tissue sarcomas treated by carbon ion radiotherapy. Clin Cancer Res 10:1764-1772
    • (2004) Clin Cancer Res , vol.10 , pp. 1764-1772
    • Zhang, H.1    Yoshikawa, K.2    Tamura, K.3
  • 21
    • 53649110097 scopus 로고    scopus 로고
    • 11C-Methionine-PET for evaluation of carbon ion radiotherapy in patients with pelvic recurrence of rectal cancer
    • 11C-Methionine-PET for evaluation of carbon ion radiotherapy in patients with pelvic recurrence of rectal cancer. Mol Imaging Biol 10:374-380
    • (2008) Mol Imaging Biol , vol.10 , pp. 374-380
    • Koizumi, M.1    Saga, T.2    Yoshikawa, K.3
  • 22
    • 33749471170 scopus 로고    scopus 로고
    • 11C]gefitinib for imaging epidermal growth factor receptor tyrosine kinase with positron emission tomography
    • 11C]gefitinib for imaging epidermal growth factor receptor tyrosine kinase with positron emission tomography. J Labelled Comp Radio-pharm 49:883-888
    • (2006) J Labelled Comp Radio-Pharm , vol.49 , pp. 883-888
    • Holt, D.P.1    Ravert, H.T.2    Dannals, R.F.3    Pomper, M.G.4
  • 23
    • 33748423744 scopus 로고    scopus 로고
    • 11C]Iressa as a new potential PET cancer imaging agent for epidermal growth factor receptor tyrosine kinase
    • 11C]Iressa as a new potential PET cancer imaging agent for epidermal growth factor receptor tyrosine kinase. Bioorg Med Chem Lett 16:4102-4106
    • (2006) Bioorg Med Chem Lett , vol.16 , pp. 4102-4106
    • Wang, J.Q.1    Gao, M.2    Miller, K.D.3    Sledge, G.W.4    Zheng, Q.H.5
  • 25
    • 43749125020 scopus 로고    scopus 로고
    • 18F]gefitinib as a molecular imaging probe for the assessment of the epidermal growth factor receptor status in malignant tumors
    • 18F]gefitinib as a molecular imaging probe for the assessment of the epidermal growth factor receptor status in malignant tumors. Eur J Nucl Med Mol Imaging 35:1089-1099
    • (2008) Eur J Nucl Med Mol Imaging , vol.35 , pp. 1089-1099
    • Su, H.1    Seimbille, Y.2    Ferl, G.Z.3
  • 26
    • 0021246955 scopus 로고
    • Independent effect of a mixed-beam regimen of fast neutrons and gamma rays on a murine fibrosarcoma
    • Ando K, Koike S, Fukuda N, Kanehira C (1984) Independent effect of a mixed-beam regimen of fast neutrons and gamma rays on a murine fibrosarcoma. Radiat Res 98:96-106
    • (1984) Radiat Res , vol.98 , pp. 96-106
    • Ando, K.1    Koike, S.2    Fukuda, N.3    Kanehira, C.4
  • 27
    • 0032904140 scopus 로고    scopus 로고
    • Accelerated reoxygenation of a murine fibrosarcoma after carbon-ion radiation
    • Ando K, Koike S, Ohira C et al (1999) Accelerated reoxygenation of a murine fibrosarcoma after carbon-ion radiation. Int J Radiat Biol 75:505-512
    • (1999) Int J Radiat Biol , vol.75 , pp. 505-512
    • Ando, K.1    Koike, S.2    Ohira, C.3
  • 28
    • 18544399873 scopus 로고    scopus 로고
    • Relative biological effectiveness of 290 Mev/u carbon ions for the growth delay of a radioresistant murine fibrosarcoma
    • Koike S, Ando K, Oohira C et al (2002) Relative biological effectiveness of 290 MeV/u carbon ions for the growth delay of a radioresistant murine fibrosarcoma. J Radiat Res 43:247-255
    • (2002) J Radiat Res , vol.43 , pp. 247-255
    • Koike, S.1    Ando, K.2    Oohira, C.3
  • 29
    • 18044384245 scopus 로고    scopus 로고
    • Biological gain of carbon-ion radiotherapy for the early response of tumor growth delay and against early response of skin reaction in mice
    • Ando K, Koike S, Uzawa A et al (2005) Biological gain of carbon-ion radiotherapy for the early response of tumor growth delay and against early response of skin reaction in mice. J Radiat Res 46:51-57
    • (2005) J Radiat Res , vol.46 , pp. 51-57
    • Ando, K.1    Koike, S.2    Uzawa, A.3
  • 30
    • 0022203215 scopus 로고
    • Computer-controlled large scale production of high specific activity [11C]Ro 15-1788 for PET studies of benzodiazepine receptors
    • Suzuki K, Inoue O, Hashimoto K, Yamasaki T, Kuchiki M, Tamate K (1985) Computer-controlled large scale production of high specific activity [11C]Ro 15-1788 for PET studies of benzodiazepine receptors. Int J Appl Radiat Isot 36:971-976
    • (1985) Int J Appl Radiat Isot , vol.36 , pp. 971-976
    • Suzuki, K.1    Inoue, O.2    Hashimoto, K.3    Yamasaki, T.4    Kuchiki, M.5    Tamate, K.6
  • 31
    • 0035076237 scopus 로고    scopus 로고
    • Sensitive measurement of positron emitters eluted from HPLC
    • Takei M, Kida T, Suzuki K (2001) Sensitive measurement of positron emitters eluted from HPLC. Appl Radiat Isot 55:229-234
    • (2001) Appl Radiat Isot , vol.55 , pp. 229-234
    • Takei, M.1    Kida, T.2    Suzuki, K.3
  • 32
    • 20144389530 scopus 로고    scopus 로고
    • Multidrug transporter ABCG2 prevents tumor cell death induced by the epidermal growth factor receptor inhibitor iressa (ZD1839, gefitinib)
    • Elkind NB, Szentpetery Z, Apati A et al (2005) Multidrug transporter ABCG2 prevents tumor cell death induced by the epidermal growth factor receptor inhibitor Iressa (ZD1839, gefitinib). Cancer Res 65:1770-1777
    • (2005) Cancer Res , vol.65 , pp. 1770-1777
    • Elkind, N.B.1    Szentpetery, Z.2    Apati, A.3
  • 33
    • 23444462507 scopus 로고    scopus 로고
    • High-affinity epidermal growth factor receptor (EGFR) irreversible inhibitors with diminished chemical reactivities as positron emission tomography (PET)-imaging agent candidates of EGFR overexpressing tumors
    • Mishani E, Abourbeh G, Jacobson O et al (2005) High-affinity epidermal growth factor receptor (EGFR) irreversible inhibitors with diminished chemical reactivities as positron emission tomography (PET)-imaging agent candidates of EGFR overexpressing tumors. J Med Chem 48:5337-5348
    • (2005) J Med Chem , vol.48 , pp. 5337-5348
    • Mishani, E.1    Abourbeh, G.2    Jacobson, O.3
  • 34
    • 33748996814 scopus 로고    scopus 로고
    • Molecular imaging of EGFR kinase activity in tumors with 124I-labeled small molecular tracer and positron emission tomography
    • Pal A, Glekas A, Doubrovin M et al (2006) Molecular imaging of EGFR kinase activity in tumors with 124I-labeled small molecular tracer and positron emission tomography. Mol Imaging Biol 8:262-277
    • (2006) Mol Imaging Biol , vol.8 , pp. 262-277
    • Pal, A.1    Glekas, A.2    Doubrovin, M.3
  • 35
    • 36248944183 scopus 로고    scopus 로고
    • Cancer molecular imaging: Radio-nuclide-based biomarkers of the epidermal growth factor receptor (EGFR)
    • Mishani E, Abourbeh G (2007) Cancer molecular imaging: radio-nuclide-based biomarkers of the epidermal growth factor receptor (EGFR). Curr Top Med Chem 7:1755-1772
    • (2007) Curr Top Med Chem , vol.7 , pp. 1755-1772
    • Mishani, E.1    Abourbeh, G.2
  • 36
    • 0035428019 scopus 로고    scopus 로고
    • Rational design of potent and selective EGFR tyrosine kinase inhibitors as anticancer agents
    • Ghosh S, Liu XP, Zheng Y, Uckun FM (2001) Rational design of potent and selective EGFR tyrosine kinase inhibitors as anticancer agents. Curr Cancer Drug Targets 1:129-140
    • (2001) Curr Cancer Drug Targets , vol.1 , pp. 129-140
    • Ghosh, S.1    Liu, X.P.2    Zheng, Y.3    Uckun, F.M.4
  • 37
    • 36749002116 scopus 로고    scopus 로고
    • Rational combination of targeted therapies as a strategy to overcome the mechanisms of resistance to inhibitors of EGFR signaling
    • Bianco R, Damiano V, Gelardi T, Daniele G, Ciardiello F, Tortora G (2007) Rational combination of targeted therapies as a strategy to overcome the mechanisms of resistance to inhibitors of EGFR signaling. Curr Pharm Des 13:3358-3367
    • (2007) Curr Pharm Des , vol.13 , pp. 3358-3367
    • Bianco, R.1    Damiano, V.2    Gelardi, T.3    Daniele, G.4    Ciardiello, F.5    Tortora, G.6
  • 38
    • 34948822890 scopus 로고    scopus 로고
    • EGFR, HER2 and VEGF pathways: Validated targets for cancer treatment
    • Press MF, Lenz HJ (2007) EGFR, HER2 and VEGF pathways: validated targets for cancer treatment. Drugs 67:2045-2075
    • (2007) Drugs , vol.67 , pp. 2045-2075
    • Press, M.F.1    Lenz, H.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.