Synthesis of [11C]gefitinib for imaging epidermal growth factor receptor tyrosine kinase with positron emission tomography

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 49, Issue 10, 2006, Pages 883-888

  Holt, Daniel P ^a   Ravert, Hayden T ^a   Dannals, Robert F ^a   Pomper, Martin G ^a   Morgan, Russell H ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Carbon 11; EGFR TK; Gefitinib; Iressa

Indexed keywords

ALKYLATION; AMINO ACIDS; CARBON; ENZYMES;

CARBON-11; EPIDERMAL GROWTH FACTOR RECEPTOR TYROSINE KINASE; EPIDERMAL GROWTH FACTOR RECEPTORS; GEFITINIB; IRESSUM; METHOXY; METHYL TRIFLATES; RADIOCHEMICAL YIELD; RECEPTOR-TYROSINE KINASE; SYNTHESISED;

POSITRON EMISSION TOMOGRAPHY;

CARBON 11; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE; GEFITINIB; GEFITINIB C 11; N (3 CHLORO 4 FLUOROPHENYL) 7 METHOXY 6 [3 (MORPHOLIN 4 YL)PROPOXY]QUINAZOLIN 4 AMINE C 11; RADIOISOTOPE; TRIFLUOROMETHANESULFONIC ACID; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DRUG STRUCTURE; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IC 50; METHYLATION; POSITRON EMISSION TOMOGRAPHY; RADIOACTIVITY; RADIOASSAY;

EID: 33749471170     PISSN: 03624803     EISSN: 10991344     Source Type: Journal    
DOI: 10.1002/jlcr.1104     Document Type: Article

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