메뉴 건너뛰기




Volumn 80, Issue 1, 2010, Pages 74-82

Hypoglycemic and antioxidant effects of honey supplementation in streptozotocin-induced diabetic rats

Author keywords

Antioxidant enzymes; Diabetes mellitus; Honey; Oxidative stress; Streptozotocin

Indexed keywords

AGROMAS; ANTIDIABETIC AGENT; ANTIOXIDANT; CATALASE; GLUCOSE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; LIPID; NATURAL PRODUCT; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

EID: 77953527612     PISSN: 03009831     EISSN: None     Source Type: Journal    
DOI: 10.1024/0300-9831/a000008     Document Type: Article
Times cited : (150)

References (36)
  • 1
    • 0033533807 scopus 로고    scopus 로고
    • Nephropathy in patients with type 2 diabetes mellitus
    • Ritz, E. and Orth, S.R. (1999) Nephropathy in patients with type 2 diabetes mellitus. N. Engl. J. Med. 341, 1127-1133.
    • (1999) N. Engl. J. Med. , vol.341 , pp. 1127-1133
    • Ritz, E.1    Orth, S.R.2
  • 2
    • 0003145765 scopus 로고
    • Kidney diseases in diabetes
    • (Harris, M.I., Cowie,C.C., Stern, M.P., Boyko, E.J., Reiber,G.E. and Bennett P.H., eds.), National Institutes of Health, Rockville, MD
    • Nelson, R.G., Knowler,W.C., Pettitt,D.J. and Bennett, P.H. (1995) Kidney diseases in diabetes. In: Diabetes in America (Harris, M.I., Cowie,C.C., Stern, M.P., Boyko, E.J., Reiber,G.E. and Bennett P.H., eds.), pp. 349-400, National Institutes of Health, Rockville, MD.
    • (1995) Diabetes in America , pp. 349-400
    • Nelson, R.G.1    Knowler, W.C.2    Pettitt, D.J.3    Bennett, P.H.4
  • 3
    • 0025732948 scopus 로고
    • Role of oxidative stress in development of complications in diabetes
    • Baynes, J.W. (1991) Role of oxidative stress in development of complications in diabetes. Diabetes 40, 405-412.
    • (1991) Diabetes , vol.40 , pp. 405-412
    • Baynes, J.W.1
  • 4
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
    • Diabetes Control and Complications Trial (DCCT) Research Group
    • Diabetes Control and Complications Trial (DCCT) Research Group. (1993) The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N. Engl. J. Med. 323, 977-986.
    • (1993) N. Engl. J. Med. , vol.323 , pp. 977-986
  • 5
    • 0021258409 scopus 로고
    • Lipid peroxidation, oxygen radicals, cell damage and antioxidant therapy
    • Halliwell, B. and Gutterridge, J.M.C. (1994) Lipid peroxidation, oxygen radicals, cell damage and antioxidant therapy. Lancet 1, 1396-1397.
    • (1994) Lancet , vol.1 , pp. 1396-1397
    • Halliwell, B.1    Gutterridge, J.M.C.2
  • 6
    • 0026049732 scopus 로고
    • The relationship of oxidative stress to thrombotic tendency in type 1 diabetic patients with nephropathy
    • Jennings, P. E., McLaren, M., Scott, N.A., Saniabadi, A.R. and Belch, J.J.F. (1991) The relationship of oxidative stress to thrombotic tendency in type 1 diabetic patients with nephropathy. Diabet. Med. 8, 860-865.
    • (1991) Diabet. Med. , vol.8 , pp. 860-865
    • Jennings, P.E.1    McLaren, M.2    Scott, N.A.3    Saniabadi, A.R.4    Belch, J.J.F.5
  • 7
    • 0026636441 scopus 로고
    • Free radicals, antioxidants and human disease: Where are we now?
    • Halliwell, B., Gutteridge, J.M. and Cross, C.E. (1992) Free radicals, antioxidants and human disease: where are we now? J. Lab. Clin. Med. 119, 598-620.
    • (1992) J. Lab. Clin. Med. , vol.119 , pp. 598-620
    • Halliwell, B.1    Gutteridge, J.M.2    Cross, C.E.3
  • 8
    • 0035430412 scopus 로고    scopus 로고
    • Effect of Antioxidant Treatment of Streptozotocin-Induced Diabetic Rats on Endoneurial Blood Flow, Motor Nerve Conduction Velocity, and Vascular Reactivity of Epineurial Arterioles of the Sciatic Nerve
    • Coppey, L.J., Gellett, J.S., Davidson, E.P., Dunlap, J.A., Lund, D.D. and Yorek, M.A. (2001) Effect of antioxidant treatment of streptozotocin-induced diabetic rats on endoneurial blood flow, motor nerve conduction velocity and vascular reactivity of epineurial arterioles of the sciatic nerve. Diabetes 50, 1927-1937. (Pubitemid 33641615)
    • (2001) Diabetes , vol.50 , Issue.8 , pp. 1927-1937
    • Coppey, L.J.1    Gellett, J.S.2    Davidson, E.P.3    Dunlap, J.A.4    Lund, D.D.5    Yorek, M.A.6
  • 10
    • 0344911324 scopus 로고
    • Honey catalase: Occurrence and some kinetic properties
    • Schepartz, A.I. (1966) Honey catalase: occurrence and some kinetic properties. J. Apical Res. 5, 167-176.
    • (1966) J. Apical Res. , vol.5 , pp. 167-176
    • Schepartz, A.I.1
  • 11
    • 0037048732 scopus 로고    scopus 로고
    • Identification and quantification of antioxidant components of honeys from various floral sources
    • Gheldof, N., Wang, X.H. and Engeseth, N.J. (2002) Identification and quantification of antioxidant components of honeys from various floral sources. J. Agric. Food Chem. 50, 5870-5877.
    • (2002) J. Agric. Food Chem. , vol.50 , pp. 5870-5877
    • Gheldof, N.1    Wang, X.H.2    Engeseth, N.J.3
  • 13
    • 0023952554 scopus 로고
    • A simple method for clinical assay of superoxide dismutase
    • Sun, Y.I., Oberley, L.W. and Ying, L. (1988) A simple method for clinical assay of superoxide dismutase. Clin. Chem. 34 (3), 497-500.
    • (1988) Clin. Chem. , vol.34 , Issue.3 , pp. 497-500
    • Sun, Y.I.1    Oberley, L.W.2    Ying, L.3
  • 14
    • 0026032095 scopus 로고
    • A simple method for determination of serum catalase activity and revision of reference range
    • Gott, L. (1991) A simple method for determination of serum catalase activity and revision of reference range. Clin. Chim. Acta 196 (2-3), 143-151.
    • (1991) Clin. Chim. Acta , vol.196 , Issue.2-3 , pp. 143-151
    • Gott, L.1
  • 15
    • 0028028353 scopus 로고
    • Oxidative enzymes of polymorphonuclear leucocytes and plasma fibrinogen, ceruloplasmin, and copper levels in Behcet's disease
    • Dogan, P., Tanrikulu, G., Soyuer, U. and Kose, K. (1994) Oxidative enzymes of polymorphonuclear leucocytes and plasma fibrinogen, ceruloplasmin, and copper levels in Behcet's disease. Clin. Biochem. 27, 413-418.
    • (1994) Clin. Biochem. , vol.27 , pp. 413-418
    • Dogan, P.1    Tanrikulu, G.2    Soyuer, U.3    Kose, K.4
  • 16
    • 0001528839 scopus 로고
    • Assay of glutathione reductase
    • (Bergmeyen HV, ed.), Verlag Chemie, Deerfield Beach, FL
    • Goldberg, D. M. and Spooner, R.J. (1983) Assay of glutathione reductase. In: Methods of Enzymatic Analysis (Bergmeyen HV, ed.), pp. 258-265, Verlag Chemie, Deerfield Beach, FL.
    • (1983) Methods of Enzymatic Analysis , pp. 258-265
    • Goldberg, D.M.1    Spooner, R.J.2
  • 17
    • 0016275313 scopus 로고
    • Glutathione-S-transferases: The First enzymatic step in mercapturic acid formation
    • Habig, W. H., Pabst, M.J. and Jakoby, W.B. (1974) Glutathione-S- transferases: The First enzymatic step in mercapturic acid formation. J. Biol. Chem. 249, 7130-7139.
    • (1974) J. Biol. Chem. , vol.249 , pp. 7130-7139
    • Habig, W.H.1    Pabst, M.J.2    Jakoby, W.B.3
  • 18
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
    • Ohkawa, H., Ohishi, N. and Yagi, K. (1979) Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal. Biochem. 95, 351-358.
    • (1979) Anal. Biochem. , vol.95 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3
  • 20
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford, M. (1976)A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.1
  • 21
    • 0017199138 scopus 로고
    • Hyperlipoproteinemia in streptozotocin-treated rats
    • Bar-On, H., Roheim, P.S. and Eder, H.E. (1976) Hyperlipoproteinemia in streptozotocin-treated rats. Diabetes 25, 509-515.
    • (1976) Diabetes , vol.25 , pp. 509-515
    • Bar-On, H.1    Roheim, P.S.2    Eder, H.E.3
  • 22
    • 34547341066 scopus 로고
    • (2nd ed.), J.B. Lippincott, Philadelphia, PA
    • Pamela, C.C. and Richard, A.H. (1994) Biochemistry (2nd ed.), pp. 269-280. J.B. Lippincott, Philadelphia, PA.
    • (1994) Biochemistry , pp. 269-280
    • Pamela, C.C.1    Richard, A.H.2
  • 23
    • 1842528325 scopus 로고    scopus 로고
    • Natural honey lowers plasma glucose, C-reactive protein, homocysteine and blood lipids in healthy, diabetic and hyperlipidemic subjects: Comparison with dextrose and sucrose
    • Al-Waili, N.S. (2004) Natural honey lowers plasma glucose, C-reactive protein, homocysteine and blood lipids in healthy, diabetic and hyperlipidemic subjects: comparison with dextrose and sucrose. J. Med. Food 7(1), 100-107.
    • (2004) J. Med. Food , vol.7 , Issue.1 , pp. 100-107
    • Al-Waili, N.S.1
  • 24
    • 0033712738 scopus 로고    scopus 로고
    • Anti-hyperglycemic effect of Eugenia jambolana and Tinospora cordifolia in experimental diabetes and their effects on key metabolic enzymes involved in carbohydrate metabolism
    • Grover, J.K., Vats, V., and Rathi, S.S. (2000) Anti-hyperglycemic effect of Eugenia jambolana and Tinospora cordifolia in experimental diabetes and their effects on key metabolic enzymes involved in carbohydrate metabolism. J. Ethnopharmacol. 73, 461-470.
    • (2000) J. Ethnopharmacol. , vol.73 , pp. 461-470
    • Grover, J.K.1    Vats, V.2    Rathi, S.S.3
  • 25
    • 0036322150 scopus 로고    scopus 로고
    • Small amounts of dietary fructose dramatically increase hepatic glucose uptake through a novel mechanism of glucokinase activation
    • Watford, M. (2002) Small amounts of dietary fructose dramatically increase hepatic glucose uptake through a novel mechanism of glucokinase activation. Nutr. Rev. 60, 253-257.
    • (2002) Nutr. Rev. , vol.60 , pp. 253-257
    • Watford, M.1
  • 26
    • 0037271731 scopus 로고    scopus 로고
    • Antidiabetic action of arachidonic acid and zinc in genetically diabetic Goto-Kakizaki rats
    • Song, M., Hwang, I., Rosenthal, M., Harris, D., Yamaguchi, D., Yi, I. and Go, V.(2003) Antidiabetic action of arachidonic acid and zinc in genetically diabetic Goto-Kakizaki rats. Metabolism 52, 7-12.
    • (2003) Metabolism , vol.52 , pp. 7-12
    • Song, M.1    Hwang, I.2    Rosenthal, M.3    Harris, D.4    Yamaguchi, D.5    Yi, I.6    Go, V.7
  • 27
    • 0035059234 scopus 로고    scopus 로고
    • Beneficial effect of supplementation with copper sulfate on STZ-diabetic mice (IDDM)
    • Sitasawad, S., Deshpande, M., Katdare, M., Tirth, S. and Parab, P. (2001) Beneficial effect of supplementation with copper sulfate on STZ-diabetic mice (IDDM). Diabetes Res. Clin. Pract. 52, 72-84.
    • (2001) Diabetes Res. Clin. Pract. , vol.52 , pp. 72-84
    • Sitasawad, S.1    Deshpande, M.2    Katdare, M.3    Tirth, S.4    Parab, P.5
  • 28
    • 0023576328 scopus 로고
    • Alterations in free radical tissue defense mechanisms in streptozotocin-induced diabetes in rat
    • Wohaieb, S.A. and Godin, D.V. (1987) Alterations in free radical tissue defense mechanisms in streptozotocin-induced diabetes in rat. Diabetes 36, 1014-1018.
    • (1987) Diabetes , vol.36 , pp. 1014-1018
    • Wohaieb, S.A.1    Godin, D.V.2
  • 29
    • 0020035640 scopus 로고
    • The effect of diabetes on the activities of the peroxide metabolism enzymes
    • Matkovics, B., Varga, S.I., Szabo, L. and Witas, H. (1982) The effect of diabetes on the activities of the peroxide metabolism enzymes. Horm. Metab. Res. 14, 77-79.
    • (1982) Horm. Metab. Res. , vol.14 , pp. 77-79
    • Matkovics, B.1    Varga, S.I.2    Szabo, L.3    Witas, H.4
  • 30
    • 0024261845 scopus 로고
    • Alterations of plasma selenium concentrations and the activities of tissue peroxide metabolism enzymes in streptozotocin-induced diabetic rats
    • Dohi, T., Kawamura, K., Morita, K., Okamoto, H. and Tsujimoto, A. (1988) Alterations of plasma selenium concentrations and the activities of tissue peroxide metabolism enzymes in streptozotocin-induced diabetic rats. Horm. Metab. Res. 20, 671-675.
    • (1988) Horm. Metab. Res. , vol.20 , pp. 671-675
    • Dohi, T.1    Kawamura, K.2    Morita, K.3    Okamoto, H.4    Tsujimoto, A.5
  • 31
    • 0025678229 scopus 로고
    • The cardioprotective effect of Mn-superoxide dismutase is lost at high doses in the postischemic rabbit heart
    • Omar, B.A. and McCord, J.M. (1990) The cardioprotective effect of Mn-superoxide dismutase is lost at high doses in the postischemic rabbit heart. Free Radic. Biol. Med. 9, 473-478.
    • (1990) Free Radic. Biol. Med. , vol.9 , pp. 473-478
    • Omar, B.A.1    McCord, J.M.2
  • 32
    • 0025940313 scopus 로고
    • The balance between Cu, Zn superoxide dismutase and catalase affects the sensitivity of mouse epidermal cells to oxidative stress
    • Amstad, P., Peskin, A. and Shah, G.L. (1991) The balance between Cu, Zn superoxide dismutase and catalase affects the sensitivity of mouse epidermal cells to oxidative stress. Biochemistry 30, 9305-9313.
    • (1991) Biochemistry , vol.30 , pp. 9305-9313
    • Amstad, P.1    Peskin, A.2    Shah, G.L.3
  • 33
    • 0033768516 scopus 로고    scopus 로고
    • Amelioration of alloxan-induced diabetes mellitus and oxidative stress in rats by oil of Eruca sativa seeds
    • El-Missiry, M.A. and El-Gindy, A.M. (2000) Amelioration of alloxan-induced diabetes mellitus and oxidative stress in rats by oil of Eruca sativa seeds. Ann. Nutr. Metab. 44, 97-100.
    • (2000) Ann. Nutr. Metab. , vol.44 , pp. 97-100
    • El-Missiry, M.A.1    El-Gindy, A.M.2
  • 34
    • 0032874845 scopus 로고    scopus 로고
    • Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defence against oxidative stress
    • Hayes, J.D. and McLellan, L.I. (1999) Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defence against oxidative stress. Free Rad. Res. 31, 273-300.
    • (1999) Free Rad. Res. , vol.31 , pp. 273-300
    • Hayes, J.D.1    McLellan, L.I.2
  • 36
    • 0031860340 scopus 로고    scopus 로고
    • Protein kinase C activation and the development of diabetic complications
    • Koya, D. and King, G.L. (1998) Protein kinase C activation and the development of diabetic complications. Diabetes 47, 859-866.
    • (1998) Diabetes , vol.47 , pp. 859-866
    • Koya, D.1    King, G.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.